hTERT promoter activity identifies osteosarcoma cells with increased EMT characteristics
Tóm tắt
Từ khóa
Tài liệu tham khảo
Savage, 2011, Using epidemiology and genomics to understand osteosarcoma etiology, Sarcoma, 2011, 548151, 10.1155/2011/548151
Mirabello, 2009, Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program, Cancer, 115, 1531, 10.1002/cncr.24121
Kalluri, 2009, The basics of epithelial-mesenchymal transition, J Clin Invest, 119, 1420, 10.1172/JCI39104
De Craene, 2013, Regulatory networks defining EMT during cancer initiation and progression, Nat Rev Cancer, 13, 97, 10.1038/nrc3447
Bastid, 2012, EMT in carcinoma progression and dissemination: facts, unanswered questions, and clinical considerations, Cancer Metastasis Rev, 31, 277, 10.1007/s10555-011-9344-6
Singh, 2010, EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer, Oncogene, 29, 4741, 10.1038/onc.2010.215
May, 2011, Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression, Breast Cancer Res, 13, 202, 10.1186/bcr2789
Morel, 2008, Generation of breast cancer stem cells through epithelial-mesenchymal transition, PLoS One, 3, e2888, 10.1371/journal.pone.0002888
Bacchetti, 1995, Telomeres and telomerase in human cancer (review), Int J Oncol, 7, 423
Meyerson, 2000, Role of telomerase in normal and cancer cells, J Clin Oncol, 18, 2626, 10.1200/JCO.2000.18.13.2626
Gomez, 2012, Telomere structure and telomerase in health and disease (review), Int J Oncol, 41, 1561, 10.3892/ijo.2012.1611
Kim, 1994, Specific association of human telomerase activity with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428
Sanders, 2004, Telomerase expression predicts unfavorable outcome in osteosarcoma, J Clin Oncol, 22, 3790, 10.1200/JCO.2004.03.043
Shay, 1997, A survey of telomerase activity in human cancer, Eur J Cancer, 33, 787, 10.1016/S0959-8049(97)00062-2
Hiyama, 2001, Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues, Neoplasia, 3, 17, 10.1038/sj.neo.7900134
Liu, 2013, Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells, Oncogene, 32, 4203, 10.1038/onc.2012.441
Wick, 1999, Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT), Gene, 232, 97, 10.1016/S0378-1119(99)00108-0
Takakura, 1999, Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells, Cancer Res, 59, 551
Cong, 1999, The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter, Hum Mol Genet, 8, 137, 10.1093/hmg/8.1.137
Niinaka, 2010, Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis, Cancer Res, 70, 9483, 10.1158/0008-5472.CAN-09-3880
Funasaka, 2007, Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells, Cancer Res, 67, 4236, 10.1158/0008-5472.CAN-06-3935
Funasaka, 2009, Phosphoglucose isomerase/autocrine motility factor mediates epithelial and mesenchymal phenotype conversions in breast cancer, Cancer Res, 69, 5349, 10.1158/0008-5472.CAN-09-0488
Kirkpatrick, 2003, hTERT mRNA expression correlates with telomerase activity in human breast cancer, Eur J Surg Oncol, 29, 321, 10.1053/ejso.2002.1374
Saretzki, 2002, hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines, Cancer Lett, 176, 81, 10.1016/S0304-3835(01)00644-9
Ito, 1998, Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer, Clin Cancer Res, 4, 1603
Shigeishi, 2011, Increased telomerase activity and hTERT expression in human salivary gland carcinomas, Oncol Lett, 2, 845
Gibbs, 2011, Evidence for the osteosarcoma stem cell, Curr Orthop Pract, 22, 322, 10.1097/BCO.0b013e318221aee8
Siclari, 2010, Targeting the osteosarcoma cancer stem cell, J Orthop Surg Res, 5, 78, 10.1186/1749-799X-5-78
Marian, 2010, The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth, Clin Cancer Res, 16, 154, 10.1158/1078-0432.CCR-09-2850
Kirkpatrick, 2004, The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression, J Carcinog, 3, 1, 10.1186/1477-3163-3-1