hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease
Yujie Fan1,2,3, James Hackland1,2, Arianna Baggiolini1,2, Lin Y. Hung4, Huiyong Zhao5,6, Paul Zumbo7,8, Polina Oberst1,2, Andrew P. Minotti1,2,3, Emiliano Hergenreder1,2,3, Sarah Najjar4, Zixing Huang4, Nelly M. Cruz9, Aaron Zhong1,2,10, Mega Sidharta1,2,10, Ting Zhou1,2,10, Elisa de Stanchina5,6, Doron Betel8,11, Richard M. White9, Michael Gershon12, Kara Gross Margolis4,13
1The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
2Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
3Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10065, USA
4Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA
5Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
6Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
7Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA
8Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA
9Cancer Biology and Genetics and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
10The SKI Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
11Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA
12Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA
13Department of Pediatrics, NYU Grossman School of Medicine, New York, NY 10010, USA
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Cell Stem Cell
Tập 30
264-282.e9
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