Zinc coordination sphere in biochemical zinc sites

citation_journal_title=EMBO J; citation_title=Characterization of two distinct MHC class II binding sites in the superantigen staphylococcal enterotoxin A; citation_author=L Abrahmsen, M Dohlsten, S Segren, P Bjork, E Jonsson, T. Kalland; citation_volume=14; citation_publication_date=1995; citation_pages=2978-2986; citation_id=CR1

citation_journal_title=Biochemistry; citation_title=Kinetic and Spectroscopic Characterization of the Gamma-Carbonic Anhydrase from the Methanoarchaeon Methanosarcina thermophila ; citation_author=BE Alber, CM Colangelo, J Dong, CM Stalhandske, TT Baird, C Tu, CA Fierke, DN Silverman, RA Scott, JG. Ferry; citation_volume=38; citation_publication_date=1999; citation_pages=13119-13128; citation_id=CR2

citation_journal_title=Proc Natl Acad Sci USA; citation_title=A carbonic anhydrase from the archaeon Methanosarcina thermophila ; citation_author=BE Alber, JG. Ferry; citation_volume=91; citation_publication_date=1994; citation_pages=6909-6913; citation_id=CR3

citation_journal_title=J Mol Biol; citation_title=Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes ; citation_author=VL Arcus, T Proft, JA Sigrell, HM Baker, JD Fraser, EN. Baker; citation_volume=299; citation_publication_date=2000; citation_pages=157-168; citation_id=CR4

citation_journal_title=J Mol Biol; citation_title=Similarities in active center geometries of zinc-containing enzymes, proteases and dehydrogenases; citation_author=P Argos, RM Garavito, W Eventoff, MG Rossmann, CI. Branden; citation_volume=126; citation_publication_date=1978; citation_pages=141-158; citation_id=CR5

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Zinc plays a key role in human and bacterial GTP cyclohydrolase I; citation_author=G Auerbach, A Herrmann, A Bracher, G Bader, M Gutlich, M Fischer, M Neukamm, M Garrido-Franco, J Richardson, H Nar, R Huber, A. Bacher; citation_volume=97; citation_publication_date=2000; citation_pages=13567-13572; citation_id=CR6

citation_title=Acyl group transfer-metalloproteinases; citation_inbook_title=Enzyme Mechanisms; citation_publication_date=1987; citation_pages=241-258; citation_id=CR7; citation_author=DS. Auld; citation_publisher=Royal Society of Chemistry Burlington House

citation_journal_title=Faraday Discuss; citation_title=Astacin family of zinc proteases; citation_author=DS. Auld; citation_volume=93; citation_publication_date=1992; citation_pages=117-120; citation_id=CR8

citation_journal_title=Structure and Bonding; citation_title=Zinc catalysis in metalloproteases; citation_author=DS. Auld; citation_volume=89; citation_publication_date=1997; citation_pages=29-50; citation_id=CR9

citation_title=Carboxypeptidase A; citation_inbook_title=Handbook of Proteolytic Enzymes; citation_publication_date=1998; citation_pages=1321-1326; citation_id=CR10; citation_author=DS. Auld; citation_publisher=Academic Press

citation_title=Carboxypeptidase A2; citation_inbook_title=Handbook of Proteolytic Enzymes; citation_publication_date=1998; citation_pages=1326-1328; citation_id=CR11; citation_author=DS. Auld; citation_publisher=Academic Press

citation_title=Zinc Sites in Metalloenzymes and Related Proteins; citation_inbook_title=Handbook on Metalloproteins; citation_publication_date=2001; citation_pages=881-959; citation_id=CR12; citation_author=DS. Auld; citation_publisher=M. Dekker

citation_title=Carboxypeptidase-A; citation_inbook_title=Hydrolytic Enzymes; citation_publication_date=1987; citation_pages=201-255; citation_id=CR13; citation_author=DS Auld; citation_author=BL. Vallee; citation_publisher=Amsterdam

citation_title=Carboxypeptidase B; citation_inbook_title=Handbook of Proteolytic Enzymes; citation_publication_date=1998; citation_pages=1333-1335; citation_id=CR14; citation_author=FX Aviles; citation_author=J. Vendrel; citation_publisher=Academic Press

citation_journal_title=J Biol Chem; citation_title=Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site; citation_author=GV Avvakumov, YA Muller, GL. Hammond; citation_volume=275; citation_publication_date=2000; citation_pages=25920-25925; citation_id=CR15

citation_journal_title=Biochem J; citation_title=Histidine residues of zinc ligands in beta-lactamase II; citation_author=GS Baldwin, A Galdes, HA Hill, BE Smith, SG Waley, EP. Abraham; citation_volume=175; citation_publication_date=1978; citation_pages=441-447; citation_id=CR16

citation_journal_title=Structure; citation_title=Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 Å resolution; citation_author=A Banbula, J Potempa, J Travis, C Fernandez-Catalan, K Mann, R Huber, W Bode, F. Medrano; citation_volume=6; citation_publication_date=1998; citation_pages=1185-1193; citation_id=CR17

citation_journal_title=CRC Crit Rev Biochem; citation_title=Aspects of the structure, function, and applications of superoxide dismutase; citation_author=JV Bannister, WH Bannister, G. Rotilio; citation_volume=22; citation_publication_date=1987; citation_pages=111-180; citation_id=CR18

citation_journal_title=J Mol Biol; citation_title=The solution structure of the Nterminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism; citation_author=G Barbato, DO Cicero, MC Nardi, C Steinkuhler, R Cortese, R De Francesco, R. Bazzo; citation_volume=289; citation_publication_date=1999; citation_pages=371-384; citation_id=CR19

Barrett AJ, Rawlings ND. 2001 MEROPS the Peptidase Database. http://www.merops.co.uk.

citation_title=Introduction: Clan MC containing metallocarboxypeptidases; citation_inbook_title=Handbook of Proteolytic Enzymes; citation_publication_date=1998; citation_pages=1318-1320; citation_id=CR21; citation_author=AJ Barrett; citation_author=ND Rawlings; citation_author=JF. Woessner; citation_publisher=Academic Press

citation_journal_title=J Mol Biol; citation_title=Crystal structure of the 50 kDa metallo protease from Serratia marcescens ; citation_author=U. Baumann; citation_volume=242; citation_publication_date=1994; citation_pages=244-251; citation_id=CR22

citation_journal_title=J Mol Biol; citation_title=Crystal structure of a complex between Serratia marcescens metallo-protease and an inhibitor from Erwinia chrysanthemi ; citation_author=U Baumann, M Bauer, S Letoffe, P Delepelaire, C. Wandersman; citation_volume=248; citation_publication_date=1995; citation_pages=653-661; citation_id=CR23

citation_journal_title=EMBO J; citation_title=Threedimensional structure of the alkaline protease of Pseudomonas aeruginosa: a two-domain protein with a calcium binding parallel beta roll motif; citation_author=U Baumann, S Wu, KM Flaherty, DB. McKay; citation_volume=12; citation_publication_date=1993; citation_pages=3357-3364; citation_id=CR24

citation_journal_title=Structure; citation_title=Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins; citation_author=B Bax, TL Blundell, J Murray-Rust, NQ. McDonald; citation_volume=5; citation_publication_date=1997; citation_pages=1275-1285; citation_id=CR25

citation_journal_title=Nat Struct Biol; citation_title=Iron center, substrate recognition and mechanism of peptide deformylase; citation_author=A Becker, I Schlichting, W Kabsch, D Groche, S Schultz, AF. Wagner; citation_volume=5; citation_publication_date=1998; citation_pages=1053-1058; citation_id=CR26

citation_journal_title=Protein Sci; citation_title=Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme; citation_author=JW Becker, AI Marcy, LL Rokosz, MG Axel, JJ Burbaum, PM Fitzgerald, PM Cameron, CK Esser, WK Hagmann, JD Hermes, JP. Springer; citation_volume=4; citation_publication_date=1995; citation_pages=1966-1976; citation_id=CR27

citation_journal_title=Biochemistry; citation_title=Threedimensional structure of phosphotriesterase: an enzyme capable of detoxifying organophosphate nerve agents; citation_author=MM Benning, JM Kuo, FM Raushel, HM. Holden; citation_volume=33; citation_publication_date=1994; citation_pages=15001-15007; citation_id=CR28

citation_journal_title=Science; citation_title=The galvanization of biology: a growing appreciation for the roles of zinc; citation_author=JM Berg, Y. Shi; citation_volume=271; citation_publication_date=1996; citation_pages=1081-1085; citation_id=CR29

citation_journal_title=Proteins; citation_title=Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+ ; citation_author=MB Berry, GN Phillips; citation_volume=32; citation_publication_date=1998; citation_pages=276-288; citation_id=CR30

citation_journal_title=Eur Biophys J; citation_title=The influence of anions and inhibitors on the catalytic metal ion in Co(II)-substituted horse liver alcohol dehydrogenase; citation_author=I Bertini, G Lanini, C Luchinat, C Haas, W Maret, M. Zeppezauer; citation_volume=14; citation_publication_date=1987; citation_pages=431-439; citation_id=CR31

citation_journal_title=J Mol Biol; citation_title=Cytidine deaminase. The 2.3 Å crystal structure of an enzyme: transition-state analog complex; citation_author=L Betts, S Xiang, SA Short, R Wolfenden, CW Carter; citation_volume=235; citation_publication_date=1994; citation_pages=635-656; citation_id=CR32

citation_journal_title=Eur J Biochem; citation_title=1.8-Å crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile; citation_author=M Betz, P Huxley, SJ Davies, Y Mushtaq, M Pieper, H Tschesche, W Bode, FX. Gomis-Ruth; citation_volume=247; citation_publication_date=1997; citation_pages=356-363; citation_id=CR33

citation_journal_title=Nat Struct Biol; citation_title=Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels; citation_author=KA Bixby, MH Nanao, NV Shen, A Kreusch, H Bellamy, PJ Pfaffinger, S. Choe; citation_volume=6; citation_publication_date=1999; citation_pages=38-43; citation_id=CR34

citation_journal_title=Nature; citation_title=Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases; citation_author=W Bode, FX Gomis-Ruth, R Huber, R Zwilling, W. Stocker; citation_volume=358; citation_publication_date=1992; citation_pages=164-167; citation_id=CR35

citation_journal_title=EMBO J; citation_title=The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity; citation_author=W Bode, P Reinemer, R Huber, T Kleine, S Schnierer, H. Tschesche; citation_volume=13; citation_publication_date=1994; citation_pages=1263-1269; citation_id=CR36

citation_journal_title=EMBO J; citation_title=Novel topology of a zinc-binding domain from a protein involved in regulating early Xenopus development; citation_author=KL Borden, JM Lally, SR Martin, NJ O'Reilly, LD Etkin, PS. Freemont; citation_volume=14; citation_publication_date=1995; citation_pages=5947-5956; citation_id=CR37

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-Å resolution: implications for catalytic proton transfer and inhibitor design; citation_author=PA Boriack-Sjodin, RW Heck, PJ Laipis, DN Silverman, DW. Christianson; citation_volume=92; citation_publication_date=1995; citation_pages=10949-10953; citation_id=CR38

citation_journal_title=J Mol Biol; citation_title=Structure of recombinant mouse collagenase-3 (MMP-13); citation_author=I Botos, E Meyer, SM Swanson, V Lemaitre, Y Eeckhout, EF. Meyer; citation_volume=292; citation_publication_date=1999; citation_pages=837-844; citation_id=CR39

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase; citation_author=Y Bourne, SM Redford, HM Steinman, JR Lepock, JA Tainer, ED Getzoff; citation_volume=93; citation_publication_date=1996; citation_pages=12774-12779; citation_id=CR40

citation_journal_title=Biochemistry; citation_title=Spinach carbonic anhydrase: investigation of the zinc-binding ligands by site-directed mutagenesis, elemental analysis, and EXAFS; citation_author=MH Bracey, J Christiansen, P Tovar, SP Cramer, SG. Bartlett; citation_volume=33; citation_publication_date=1994; citation_pages=13126-13131; citation_id=CR41

citation_journal_title=Biochemistry; citation_title=Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states; citation_author=DE Brodersen, J Nyborg, M. Kjeldgaard; citation_volume=38; citation_publication_date=1999; citation_pages=1695-1704; citation_id=CR42

citation_journal_title=Biochemistry; citation_title=Matrilysin-inhibitor complexes: common themes among metalloproteases; citation_author=MF Browner, WW Smith, AL. Castelhano; citation_volume=34; citation_publication_date=1995; citation_pages=6602-6610; citation_id=CR43

citation_journal_title=Biochemistry; citation_title=Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family; citation_author=JL Buchbinder, RC Stephenson, MJ Dresser, JW Pitera, TS Scanlan, RJ. Fletterick; citation_volume=37; citation_publication_date=1998; citation_pages=5096-5106; citation_id=CR44

citation_journal_title=Biochemistry; citation_title=Native carboxypeptidase A in a new crystal environment reveals a different conformation of the important tyrosine 248; citation_author=JT Bukrinsky, MJ Bjerrum, A. Kadziola; citation_volume=37; citation_publication_date=1998; citation_pages=16555-16564; citation_id=CR45

citation_journal_title=JMol Biol; citation_title=6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding; citation_author=DM Burgisser, B Thony, U Redweik, D Hess, CW Heizmann, R Huber, H. Nar; citation_volume=253; citation_publication_date=1995; citation_pages=358-369; citation_id=CR46

citation_journal_title=J Mol Biol; citation_title=Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin; citation_author=SK Burley, PR David, RM Sweet, A Taylor, WN. Lipscomb; citation_volume=224; citation_publication_date=1992; citation_pages=113-140; citation_id=CR47

citation_journal_title=Mol Cell; citation_title=The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance; citation_author=DE Bussiere, SD Pratt, L Katz, JM Severin, T Holzman, CH. Park; citation_volume=2; citation_publication_date=1998; citation_pages=75-84; citation_id=CR48

citation_journal_title=Nat Struct Biol; citation_title=Solution structure of the N-terminal zinc binding domain of HIV-1 integrase; citation_author=M Cai, R Zheng, M Caffrey, R Craigie, GM Clore, AM. Gronenborn; citation_volume=4; citation_publication_date=1997; citation_pages=567-577; citation_id=CR49

citation_journal_title=EMBO J; citation_title=Crystal structure of human glyoxalase I-evidence for gene duplication and 3D domain swapping; citation_author=AD Cameron, B Olin, M Ridderstrom, B Mannervik, TA. Jones; citation_volume=16; citation_publication_date=1997; citation_pages=3386-3395; citation_id=CR50

citation_journal_title=Biochemistry; citation_title=Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue; citation_author=AD Cameron, M Ridderstrom, B Olin, MJ Kavarana, DJ Creighton, B. Mannervik; citation_volume=38; citation_publication_date=1999; citation_pages=13480-13490; citation_id=CR51

citation_journal_title=Structure Fold Des; citation_title=Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue; citation_author=AD Cameron, M Ridderstrom, B Olin, B. Mannervik; citation_volume=7; citation_publication_date=1999; citation_pages=1067-1078; citation_id=CR52

citation_journal_title=Acta Cryst D; citation_title=1.85 Å resolution structure of the zinc (II) beta-lactamase from Bacillus cereus ; citation_author=A Carfi, E Duee, M Galleni, JM Frere, O. Dideberg; citation_volume=54; citation_publication_date=1998; citation_pages=313-323; citation_id=CR53

citation_journal_title=Acta Cryst D Biol Cryst; citation_title=X-ray structure of the ZnII beta-lactamase from Bac-teroides fragilis in an orthorhombic crystal form; citation_author=A Carfi, E Duee, R Paul-Soto, M Galleni, JM Frere, O. Dideberg; citation_volume=54; citation_publication_date=1998; citation_pages=45-57; citation_id=CR54

citation_journal_title=EMBO J; citation_title=The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold; citation_author=A Carfi, S Pares, E Duee, M Galleni, C Duez, JM Frere, O. Dideberg; citation_volume=14; citation_publication_date=1995; citation_pages=4914-4921; citation_id=CR55

citation_journal_title=Biochemistry; citation_title=Cytidine Deaminases from B. subtilis and E. coli: Compensating effects of changing zinc coordination and quaternary structure; citation_author=DC Carlow, CW Carter, N Mejlhede, J Neuhard, R. Wolfenden; citation_volume=38; citation_publication_date=1999; citation_pages=12258-12265; citation_id=CR56

citation_journal_title=FEBS Lett; citation_title=Crystal structure of the cyanideinhibited Xenopus laevis Cu,Zn superoxide dismutase at 98 K; citation_author=KD Carugo, A Battistoni, MT Carri, F Polticelli, A Desideri, G Rotilio, A Coda, M. Bolognesi; citation_volume=349; citation_publication_date=1994; citation_pages=93-98; citation_id=CR57

citation_journal_title=Biochemistry; citation_title=Site-directed mutagenesis of the active site glutamate in human matrilysin: investigation of its role in catalysis; citation_author=J Cha, DS. Auld; citation_volume=36; citation_publication_date=1997; citation_pages=16019-16024; citation_id=CR58

citation_journal_title=Biochemistry; citation_title=Crystal structure of the Escherichia coli peptide deformylase; citation_author=MK Chan, W Gong, PT Rajagopalan, B Hao, CM Tsai, D. Pei; citation_volume=36; citation_publication_date=1997; citation_pages=13904-13909; citation_id=CR59

citation_journal_title=EMBO J; citation_title=Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization; citation_author=L Chantalat, D Leroy, O Filhol, A Nueda, MJ Benitez, EM Chambaz, C Cochet, O. Dideberg; citation_volume=18; citation_publication_date=1999; citation_pages=2930-2940; citation_id=CR60

citation_journal_title=J Mol Biol; citation_title=Crystal structure of the stromelysin catalytic domain at 2.0 Å resolution: inhibitor-induced conformational changes; citation_author=L Chen, TJ Rydel, F Gu, CM Dunaway, S Pikul, KM Dunham, BL. Barnett; citation_volume=293; citation_publication_date=1999; citation_pages=545-557; citation_id=CR61

citation_journal_title=Biochemistry; citation_title=Structural characterization of the active site of Brucella abortus Cu-Zn superoxide dismutase: a 15N and 1H NMR investigation; citation_author=YL Chen, S Park, RW Thornburg, LB Tabatabai, A. Kintanar; citation_volume=34; citation_publication_date=1995; citation_pages=12265-12275; citation_id=CR62

citation_journal_title=Proc Natl Acad Sci USA; citation_title=The structure of bacteriophage T7 lysozyme, a zinc amidase and an inhibitor of T7 RNA polymerase; citation_author=X Cheng, X Zhang, JW Pflugrath, FW. Studier; citation_volume=91; citation_publication_date=1994; citation_pages=4034-4038; citation_id=CR63

citation_journal_title=Eur J Biochem; citation_title=The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit; citation_author=B Chevrier, H D'Orchymont, C Schalk, C Tarnus, D. Moras; citation_volume=237; citation_publication_date=1996; citation_pages=393-398; citation_id=CR64

citation_journal_title=Structure; citation_title=Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family; citation_author=B Chevrier, C Schalk, H D'Orchymont, JM Rondeau, D Moras, C. Tarnus; citation_volume=2; citation_publication_date=1994; citation_pages=283-291; citation_id=CR65

citation_journal_title=Biochemistry; citation_title=Flexibility of liver alcohol dehydrogenase in stereoselective binding of 3-butylthiolane 1-oxides; citation_author=H Cho, S Ramaswamy, BV. Plapp; citation_volume=36; citation_publication_date=1997; citation_pages=382-389; citation_id=CR66

citation_journal_title=Biochemistry; citation_title=Inhibition of carboxypeptidase A by D-pencillamine: Mechanism and implications for drug design; citation_author=CR Chong, DS. Auld; citation_volume=39; citation_publication_date=2000; citation_pages=7580-7588; citation_id=CR67

citation_journal_title=Annu Rev Biochem; citation_title=Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymes; citation_author=DW Christianson, JD. Cox; citation_volume=68; citation_publication_date=1999; citation_pages=33-57; citation_id=CR68

citation_journal_title=Acc Chem Res; citation_title=Carbonic anhydrase: Evolution of the design of the zinc binding site by nature and by design; citation_author=DW Christianson, CA. Fierke; citation_volume=29; citation_publication_date=1996; citation_pages=331-339; citation_id=CR69

citation_journal_title=Acc Chem Res; citation_title=Carboxypeptidase A; citation_author=DW Christianson, WN. Lipscomb; citation_volume=22; citation_publication_date=1989; citation_pages=62-69; citation_id=CR70

citation_journal_title=Nat Struct Biol; citation_title=The X-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution; citation_author=A Cleasby, A Wonacott, T Skarzynski, RE Hubbard, GJ Davies, AE Proudfoot, AR Bernard, MA Payton, TN. Wells; citation_volume=3; citation_publication_date=1996; citation_pages=470-479; citation_id=CR71

citation_journal_title=Biochemistry; citation_title=Overproduction and characterization of a dimeric non-zinc glyoxalase I from Escherichia coli: evidence for optimal activation by nickel ions; citation_author=SL Clugston, JF Barnard, R Kinach, D Miedema, R Ruman, E Daub, JF. Honek; citation_volume=37; citation_publication_date=1998; citation_pages=8754-8763; citation_id=CR72

citation_journal_title=Annu Rev Biophys Biomol Struct; citation_title=Structure and mechanism of alkaline phosphatase; citation_author=JE. Coleman; citation_volume=21; citation_publication_date=1992; citation_pages=441-483; citation_id=CR73

citation_journal_title=Curr Opin Chem Biol; citation_title=Zinc enzymes; citation_author=JE. Coleman; citation_volume=2; citation_publication_date=1998; citation_pages=222-234; citation_id=CR74

citation_journal_title=EMBO J; citation_title=Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity; citation_author=M Coll, A Guasch, FX Aviles, R. Huber; citation_volume=10; citation_publication_date=1991; citation_pages=1-9; citation_id=CR75

citation_journal_title=J Biol Chem; citation_title=Interdomain motion in liver alcohol dehydrogenase. Structural and energetic analysis of the hinge bending mode; citation_author=F Colonna-Cesari, D Perahia, M Karplus, H Eklund, CI Branden, O. Tapia; citation_volume=261; citation_publication_date=1986; citation_pages=15273-15280; citation_id=CR76

citation_journal_title=Biochemistry; citation_title=Crystal structure of the IMP-1 metallo betalactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor; citation_author=NO Concha, CA Janson, P Rowling, S Pearson, CA Cheever, BP Clarke, C Lewis, M Galleni, JM Frere, DJ Payne, JH Bateson, SS. Abdel-Meguid; citation_volume=39; citation_publication_date=2000; citation_pages=4288-4298; citation_id=CR77

citation_journal_title=Structure; citation_title=Crystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis ; citation_author=NO Concha, BA Rasmussen, K Bush, O. Herzberg; citation_volume=4; citation_publication_date=1996; citation_pages=823-836; citation_id=CR78

citation_journal_title=Science; citation_title=Structure of nitric oxide synthase oxygenase dimer with pterin and substrate; citation_author=BR Crane, AS Arvai, DK Ghosh, C Wu, ED Getzoff, DJ Stuehr, JA. Tainer; citation_volume=279; citation_publication_date=1998; citation_pages=2121-2126; citation_id=CR79

citation_journal_title=EMBO J; citation_title=Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding; citation_author=DS Daniels, CD Mol, AS Arvai, S Kanugula, AE Pegg, JA. Tainer; citation_volume=19; citation_publication_date=2000; citation_pages=1719-1730; citation_id=CR80

citation_journal_title=J Biol Chem; citation_title=X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding; citation_author=GJ Davis, WF Bosron, CL Stone, K Owusu-Dekyi, TD. Hurley; citation_volume=271; citation_publication_date=1996; citation_pages=17057-17061; citation_id=CR81

citation_journal_title=Biochemistry; citation_title=A zinc binding site in viral serine proteinases; citation_author=R De Francesco, A Urbani, MC Nardi, L Tomei, C Steinkuhler, A. Tramontano; citation_volume=35; citation_publication_date=1996; citation_pages=13282-13287; citation_id=CR82

citation_journal_title=Structure; citation_title=Xray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily; citation_author=V Dhanaraj, QZ Ye, LL Johnson, DJ Hupe, DF Ortwine, JB Dunbar, JR Rubin, A Pavlovsky, C Humblet, TL. Blundell; citation_volume=4; citation_publication_date=1996; citation_pages=375-386; citation_id=CR83

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Zinc-dependent dimers observed in crystals of human endostatin; citation_author=YH Ding, K Javaherian, KM Lo, R Chopra, T Boehm, J Lanciotti, BA Harris, Y Li, R Shapiro, E Hohenester, R Timpl, J Folkman, DC. Wiley; citation_volume=95; citation_publication_date=1998; citation_pages=10443-10448; citation_id=CR84

citation_journal_title=J Mol Biol; citation_title=Crystal structure of yeast Cu,Zn superoxide dismutase. Crystallographic refinement at 2.5 Å resolution; citation_author=K Djinovic, G Gatti, A Coda, L Antolini, G Pelosi, A Desideri, M Falconi, F Marmocchi, G Rotilio, M. Bolognesi; citation_volume=225; citation_publication_date=1992; citation_pages=791-809; citation_id=CR85

citation_journal_title=Klin Wochenschr; citation_title=New type of hepatic porphyria with porphobilinogen synthase defect and intermittent acute clinical manifestation; citation_author=M Doss, R von Tiepermann, J Schneider, H. Schmid; citation_volume=57; citation_publication_date=1979; citation_pages=1123-1127; citation_id=CR86

citation_journal_title=J Mol Biol; citation_title=The spatial structure of the class II Lfuculose-1-phosphate aldolase from Escherichia coli ; citation_author=MK Dreyer, GE. Schulz; citation_volume=231; citation_publication_date=1993; citation_pages=549-553; citation_id=CR87

citation_journal_title=J Mol Biol; citation_title=Catalytic mechanism of the metaldependent fuculose aldolase from Escherichia coli as derived from the structure; citation_author=MK Dreyer, GE. Schulz; citation_volume=259; citation_publication_date=1996; citation_pages=458-466; citation_id=CR88

citation_journal_title=Biochemistry; citation_title=The methionyl aminopeptidase from Escherichia coli can function as an iron(II) enzyme; citation_author=VM D'souza, RC. Holz; citation_volume=38; citation_publication_date=1999; citation_pages=11079-11085; citation_id=CR89

citation_journal_title=J Biol Chem; citation_title=The astacin family of metalloendopeptidases; citation_author=E Dumermuth, EE Sterchi, WP Jiang, RL Wolz, JS Bond, AV Flannery, RJ. Beynon; citation_volume=266; citation_publication_date=1991; citation_pages=21381-21385; citation_id=CR90

citation_journal_title=Protein Sci; citation_title=Structure of streptococcal pyrogenic exotoxin A reveals a novel metal cluster; citation_author=CA Earhart, GM Vath, M Roggiani, PM Schlievert, DH. Ohlendorf; citation_volume=9; citation_publication_date=2000; citation_pages=1847-1851; citation_id=CR91

citation_journal_title=J Mol Biol; citation_title=Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate; citation_author=MP Egloff, PT Cohen, P Reinemer, D. Barford; citation_volume=254; citation_publication_date=1995; citation_pages=942-959; citation_id=CR92

citation_journal_title=Curr Biol; citation_title=The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc; citation_author=AP Eijkelenboom, FM van den Ent, A Vos, JF Doreleijers, K Hard, TD Tullius, RH Plasterk, R Kaptein, R. Boelens; citation_volume=7; citation_publication_date=1997; citation_pages=739-746; citation_id=CR93

citation_journal_title=J Biomol NMR; citation_title=Refined solution structure of the dimeric N-terminal HHCC domain of HIV-2 integrase; citation_author=AP Eijkelenboom, FM van den Ent, R Wechselberger, RH Plasterk, R Kaptein, R. Boelens; citation_volume=18; citation_publication_date=2000; citation_pages=119-128; citation_id=CR94

citation_journal_title=Biochem Soc Trans; citation_title=Coenzyme binding in alcohol dehydrogenase; citation_author=H. Eklund; citation_volume=17; citation_publication_date=1989; citation_pages=293-296; citation_id=CR95

citation_title=Alcohol Dehydrogenase; citation_inbook_title=Biological Macromolecules and Assemblies: Vol. 3, Active Sites of Enzumes; citation_publication_date=1987; citation_pages=73-143; citation_id=CR96; citation_author=H Eklund; citation_author=CI. Branden; citation_publisher=John Wiley & Sons, Inc

citation_journal_title=FEBS Lett; citation_title=The structure of horse liver alcohol dehydrogenase; citation_author=H Eklund, B Nordstrom, E Zeppezauer, G Soderlund, I Ohlsson, T Boiwe, CI. Branden; citation_volume=44; citation_publication_date=1974; citation_pages=200-204; citation_id=CR97

citation_journal_title=J Mol Biol; citation_title=Three-dimensional structure of horse liver alcohol dehydrogenase at 2-4 Å resolution; citation_author=H Eklund, B Nordstrom, E Zeppezauer, G Soderlund, I Ohlsson, T Boiwe, BO Soderberg, O Tapia, CI Branden, A. Akeson; citation_volume=102; citation_publication_date=1976; citation_pages=27-59; citation_id=CR98

citation_journal_title=J Mol Biol; citation_title=Structure of a triclinic ternary complex of horse liver alcohol dehydrogenase at 2.9 Å resolution; citation_author=H Eklund, JP Samama, L Wallen, CI Branden, A Akeson, TA. Jones; citation_volume=146; citation_publication_date=1981; citation_pages=561-587; citation_id=CR99

citation_journal_title=Proteins; citation_title=Refined structure of bovine carbonic anhydrase III at 2.0 Å resolution; citation_author=AE Eriksson, A. Liljas; citation_volume=16; citation_publication_date=1993; citation_pages=29-42; citation_id=CR100

citation_journal_title=Acta Cryst D; citation_title=MAD analyses of yeast 5-aminolaevulinate dehydratase: their use in structure determination and in defining the metal-binding sites; citation_author=PT Erskine, EM Duke, IJ Tickle, NM Senior, MJ Warren, JB. Cooper; citation_volume=56; citation_publication_date=2000; citation_pages=421-430; citation_id=CR101

citation_journal_title=Protein Sci; citation_title=The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid; citation_author=PT Erskine, R Newbold, J Roper, A Coker, MJ Warren, PM Shoolingin-Jordan, SP Wood, JB. Cooper; citation_volume=8; citation_publication_date=1999; citation_pages=1250-1256; citation_id=CR102

citation_journal_title=Biochemistry; citation_title=X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 Å resolution; citation_author=PT Erskine, E Norton, JB Cooper, R Lambert, A Coker, G Lewis, P Spencer, M Sarwar, SP Wood, MJ Warren, PM. Shoolingin-Jordan; citation_volume=38; citation_publication_date=1999; citation_pages=4266-4276; citation_id=CR103

citation_journal_title=Nat Struc Biol; citation_title=X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase; citation_author=PT Erskine, N Senior, S Awan, R Lambert, G Lewis, IJ Tickle, M Sarwar, P Spencer, P Thomas, MJ Warren, PM Shoolingin-Jordan, SP Wood, JB. Cooper; citation_volume=4; citation_publication_date=1997; citation_pages=1025-1031; citation_id=CR104

citation_journal_title=Science; citation_title=Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase; citation_author=AG Estevez, JP Crow, JB Sampson, C Reiter, Y Zhuang, GJ Richardson, MM Tarpey, L Barbeito, JS. Beckman; citation_volume=286; citation_publication_date=1999; citation_pages=2498-2500; citation_id=CR105

citation_journal_title=Biochemistry; citation_title=Crystal structure of the zinc-dependent betalactamase from Bacillus cereus at 1.9 Å resolution: binuclear active site with features of a mononuclear enzyme; citation_author=SM Fabiane, MK Sohi, T Wan, DJ Payne, JH Bateson, T Mitchell, BJ. Sutton; citation_volume=37; citation_publication_date=1998; citation_pages=12404-12411; citation_id=CR106

citation_journal_title=J Biol Chem; citation_title=Structural evolution of an enzyme specificity. The structure of rat carboxypeptidase A2 at 1.9 Å-resolution; citation_author=Z Faming, B Kobe, CB Stewart, WJ Rutter, EJ. Goldsmith; citation_volume=266; citation_publication_date=1991; citation_pages=24606-24612; citation_id=CR107

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Cation-promoted association of a regulatory and target protein is controlled by protein phosphorylation; citation_author=M Feese, DW Pettigrew, ND Meadow, S Roseman, SJ. Remington; citation_volume=91; citation_publication_date=1994; citation_pages=3544-3548; citation_id=CR108

citation_journal_title=Biochemistry; citation_title=Structural studies of the Escherichia coli signal transducing protein IIAGlc: implications for target recognition; citation_author=MD Feese, L Comolli, ND Meadow, S Roseman, SJ. Remington; citation_volume=36; citation_publication_date=1997; citation_pages=16087-16096; citation_id=CR109

citation_journal_title=Nat Struct Biol; citation_title=Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation; citation_author=TO Fischmann, A Hruza, XD Niu, JD Fossetta, CA Lunn, E Dolphin, AJ Prongay, P Reichert, DJ Lundell, SK Narula, PC. Weber; citation_volume=6; citation_publication_date=1999; citation_pages=233-242; citation_id=CR110

citation_journal_title=J Mol Biol; citation_title=Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface; citation_author=KT Forest, PR Langford, JS Kroll, ED Getzoff; citation_volume=296; citation_publication_date=2000; citation_pages=145-153; citation_id=CR111

citation_journal_title=J Mol Biol; citation_title=Methionyl-tRNA synthetase zinc binding domain. Three-dimensional structure and homology with rubredoxin and gag retroviral proteins; citation_author=D Fourmy, F Dardel, S. Blanquet; citation_volume=231; citation_publication_date=1993; citation_pages=1078-1089; citation_id=CR112

citation_journal_title=J Mol Biol; citation_title=Mapping of the zinc binding domain of Escherichia coli methionyl-tRNA synthetase; citation_author=D Fourmy, T Meinnel, Y Mechulam, S. Blanquet; citation_volume=231; citation_publication_date=1993; citation_pages=1068-1077; citation_id=CR113

citation_journal_title=Biochemistry; citation_title= Pseudomonas aeruginosa contains a novel type V porphobilinogen synthase with no required catalytic metal ions; citation_author=N Frankenberg, D Jahn, EK. Jaffe; citation_volume=38; citation_publication_date=1999; citation_pages=13976-13982; citation_id=CR114

citation_journal_title=Mol Med Today; citation_title=Superantigens-powerful modifiers of the immune system; citation_author=J Fraser, V Arcus, P Kong, E Baker, T. Proft; citation_volume=6; citation_publication_date=2000; citation_pages=125-132; citation_id=CR115

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Zinc regulates the function of two superantigens; citation_author=JD Fraser, RG Urban, JL Strominger, H. Robinson; citation_volume=89; citation_publication_date=1992; citation_pages=5507-5511; citation_id=CR116

citation_journal_title=Nat Struct Biol; citation_title=Novel zincbinding centre in thermoacidophilic archaeal ferredoxins [letter]; citation_author=T Fujii, Y Hata, T Wakagi, N Tanaka, T. Oshima; citation_volume=3; citation_publication_date=1996; citation_pages=834-837; citation_id=CR117

citation_journal_title=J Mol Biol; citation_title=Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 Å resolution; citation_author=M Fujinaga, MN. James; citation_volume=195; citation_publication_date=1987; citation_pages=373-396; citation_id=CR118

citation_journal_title=Cell; citation_title=Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase; citation_author=S Fukai, O Nureki, S Sekine, A Shimada, J Tao, DG Vassylyev, S. Yokoyama; citation_volume=103; citation_publication_date=2000; citation_pages=793-803; citation_id=CR119

citation_journal_title=Biochemistry; citation_title=X-ray absorption studies of the Zn2+ site of glyoxalase I; citation_author=L Garcia-Iniguez, L Powers, B Chance, S Sellin, B Mannervik, AS. Mildvan; citation_volume=23; citation_publication_date=1984; citation_pages=685-689; citation_id=CR120

citation_journal_title=EMBO J; citation_title=The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen; citation_author=I Garcia-Saez, D Reverter, J Vendrell, FX Aviles, M. Coll; citation_volume=16; citation_publication_date=1997; citation_pages=6906-6913; citation_id=CR121

citation_journal_title=Biochemistry; citation_title=Significance of metal ions in galactose-1-phosphate uridylyltransferase: An essential structural zinc and a nonessential structural iron; citation_author=S Geeganage, PA. Frey; citation_volume=38; citation_publication_date=1999; citation_pages=13398-133406; citation_id=CR122

citation_journal_title=EMBO J; citation_title=Inducible ni-tric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction; citation_author=DK Ghosh, BR Crane, S Ghosh, D Wolan, R Gachhui, C Crooks, A Presta, JA Tainer, ED Getzoff, DJ. Stuehr; citation_volume=18; citation_publication_date=1999; citation_pages=6260-6270; citation_id=CR123

citation_title=Evolution of DD-peptidases and betalactamases; citation_inbook_title=Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function; citation_publication_date=1988; citation_pages=268-284; citation_id=CR124; citation_author=JM. Ghuysen; citation_publisher=American Society for Microbiology

citation_journal_title=Annu Rev Pharmacol Toxicol; citation_title=The potential of farnesyltransferase inhibitors as cancer chemotherapeutics; citation_author=JB Gibbs, A. Oliff; citation_volume=37; citation_publication_date=1997; citation_pages=143-166; citation_id=CR125

citation_journal_title=Acta Cryst D; citation_title=Interactions of Streptomyces griseus aminopeptidase with a methionine product analogue: a structural study at 1.53 Å resolution; citation_author=R Gilboa, HM Greenblatt, M Perach, A Spungin-Bialik, U Lessel, G Wohlfahrt, D Schomburg, S Blumberg, G. Shoham; citation_volume=56; citation_publication_date=2000; citation_pages=551-558; citation_id=CR126

citation_journal_title=EMBO J; citation_title=Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily; citation_author=FX Gomis-Ruth, V Companys, Y Qian, LD Fricker, J Vendrell, FX Aviles, M. Coll; citation_volume=18; citation_publication_date=1999; citation_pages=5817-5826; citation_id=CR127

citation_journal_title=EMBO J; citation_title=The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C; citation_author=FX Gomis-Ruth, M Gomez, W Bode, R Huber, FX. Aviles; citation_volume=14; citation_publication_date=1995; citation_pages=4387-4394; citation_id=CR128

citation_journal_title=EMBO J; citation_title=First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/ collagenases; citation_author=FX Gomis-Ruth, LF Kress, W. Bode; citation_volume=12; citation_publication_date=1993; citation_pages=4151-4157; citation_id=CR129

citation_journal_title=JMol Biol; citation_title=Refined 2.0 Å X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin; citation_author=FX Gomis-Ruth, LF Kress, J Kellermann, I Mayr, X Lee, R Huber, W. Bode; citation_volume=239; citation_publication_date=1994; citation_pages=513-544; citation_id=CR130

citation_journal_title=J Mol Biol; citation_title=Refined 1.8 Å X-ray crystal structure of astacin, a zincendopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin; citation_author=FX Gomis-Ruth, W Stocker, R Huber, R Zwilling, W. Bode; citation_volume=229; citation_publication_date=1993; citation_pages=945-968; citation_id=CR131

citation_journal_title=J Mol Biol; citation_title=Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus ; citation_author=W Gong, X Zhu, S Liu, M Teng, L. Niu; citation_volume=283; citation_publication_date=1998; citation_pages=657-668; citation_id=CR132

citation_journal_title=Nat Struct Biol; citation_title=The NMR structure of the inhibited catalytic domain of human stromelysin-1; citation_author=PR Gooley, JF O'Connell, AI Marcy, GC Cuca, SP Salowe, BL Bush, JD Hermes, CK Esser, WK Hagmann, JP Springer, BA. Johnson; citation_volume=1; citation_publication_date=1994; citation_pages=111-118; citation_id=CR133

citation_journal_title=Nat Struct Biol; citation_title=Structure of astacin with a transitionstate analogue inhibitor [letter]; citation_author=F Grams, V Dive, A Yiotakis, I Yiallouros, S Vassiliou, R Zwilling, W Bode, W. Stocker; citation_volume=3; citation_publication_date=1996; citation_pages=671-675; citation_id=CR134

citation_journal_title=J Mol Biol; citation_title= Streptomyces griseus aminopeptidase: X-ray crystallographic structure at 1.75 Å resolution; citation_author=HM Greenblatt, O Almog, B Maras, A Spungin-Bialik, D Barra, S Blumberg, G. Shoham; citation_volume=265; citation_publication_date=1997; citation_pages=620-636; citation_id=CR135

citation_journal_title=Cell; citation_title=X-ray structure of calcineurin inhibited by the immunophilinimmunosuppressant FKBP12-FK506 complex; citation_author=JP Griffith, JL Kim, EE Kim, MD Sintchak, JA Thomson, MJ Fitzgibbon, MA Fleming, PR Caron, K Hsiao, MA. Navia; citation_volume=82; citation_publication_date=1995; citation_pages=507-522; citation_id=CR136

citation_journal_title=J Mol Biol; citation_title=Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation; citation_author=A Guasch, M Coll, FX Aviles, R. Huber; citation_volume=224; citation_publication_date=1992; citation_pages=141-157; citation_id=CR137

citation_journal_title=Structure Fold Des; citation_title=Crystal structure of mammalian purple acid phosphatase; citation_author=LW Guddat, AS McAlpine, D Hume, S Hamilton, J de Jersey, JL. Martin; citation_volume=7; citation_publication_date=1999; citation_pages=757-767; citation_id=CR138

citation_journal_title=Cell; citation_title=Crystal structure of the delta’ subunit of the clamp-loader complex of E. coli DNA polymerase III; citation_author=B Guenther, R Onrust, A Sali, M O'Donnell, J. Kuriyan; citation_volume=91; citation_publication_date=1997; citation_pages=335-345; citation_id=CR139

citation_journal_title=Biochem Biophys Res Commun; citation_title=Leukotriene A4 hydrolase: a zinc metalloenzyme; citation_author=JZ Haeggstrom, A Wetterholm, R Shapiro, BL Vallee, B. Samuelsson; citation_volume=172; citation_publication_date=1990; citation_pages=965-700; citation_id=CR140

citation_journal_title=J Mol Biol; citation_title=The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules; citation_author=M Hakansson, K Petersson, H Nilsson, G Forsberg, P Bjork, P Antonsson, LA. Svensson; citation_volume=302; citation_publication_date=2000; citation_pages=527-537; citation_id=CR141

citation_journal_title=Nature; citation_title=A potential catalytic site revealed by the 1.7-Å crystal structure of the aminoterminal signalling domain of Sonic hedgehog; citation_author=TM Hall, JA Porter, PA Beachy, DJ. Leahy; citation_volume=378; citation_publication_date=1995; citation_pages=212-216; citation_id=CR142

citation_journal_title=J Biochem (Tokyo); citation_title=Crystal structure of Serratia protease, a zinc-dependent proteinase from Serratia sp. E-15, containing a beta-sheet coil motif at 2.0 Å resolution; citation_author=K Hamada, Y Hata, Y Katsuya, H Hiramatsu, T Fujiwara, Y. Katsube; citation_volume=119; citation_publication_date=1996; citation_pages=844-851; citation_id=CR143

citation_journal_title=J Mol Biol; citation_title=The solution structure of ribosomal protein L36 from Thermus thermophilus reveals a zinc-ribbon-like fold; citation_author=T Hard, A Rak, P Allard, L Kloo, M. Garber; citation_volume=296; citation_publication_date=2000; citation_pages=169-180; citation_id=CR144

citation_journal_title=Biochemistry; citation_title=Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation; citation_author=MM He, SL Clugston, JF Honek, BW. Matthews; citation_volume=39; citation_publication_date=2000; citation_pages=8719-8727; citation_id=CR145

citation_journal_title=Biochemistry; citation_title=Zn(II) dependence of the Aeromonas hydrophila AE036 metallo-beta-lactamase activity and stability; citation_author=M Hernandez Valladares, A Felici, G Weber, HW Adolph, M Zeppezauer, GM Rossolini, G Amicosante, JM Frere, M. Galleni; citation_volume=36; citation_publication_date=1997; citation_pages=11534-11541; citation_id=CR146

citation_journal_title=Mol Phylogenet Evol; citation_title=Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families; citation_author=D Hewett-Emmett, RE. Tashian; citation_volume=5; citation_publication_date=1996; citation_pages=50-77; citation_id=CR147

citation_journal_title=J Mol Biol; citation_title=Variable zinc coordination in endostatin; citation_author=E Hohenester, T Sasaki, K Mann, R. Timpl; citation_volume=297; citation_publication_date=2000; citation_pages=1-6; citation_id=CR148

citation_journal_title=Protein Sci; citation_title=Structural analysis of zinc substitutions in the active site of thermolysin; citation_author=DR Holland, AC Hausrath, D Juers, BW. Matthews; citation_volume=4; citation_publication_date=1995; citation_pages=1955-1965; citation_id=CR149

citation_journal_title=J Biol Chem; citation_title=A model of the transition state in the alkaline phosphatase reaction; citation_author=KM Holtz, B Stec, ER. Kantrowitz; citation_volume=274; citation_publication_date=1999; citation_pages=8351-8354; citation_id=CR150

citation_journal_title=Nat Struct Biol; citation_title=Solution structure of a cysteine rich domain of rat protein kinase C; citation_author=U Hommel, M Zurini, M. Luyten; citation_volume=1; citation_publication_date=1994; citation_pages=383-387; citation_id=CR151

citation_journal_title=J Mol Biol; citation_title=Crystal and molecular structures of native and CTPliganded aspartate carbamoyltransferase from Escherichia coli ; citation_author=RB Honzatko, JL Crawford, HL Monaco, JE Ladner, BF Ewards, DR Evans, SG Warren, DC Wiley, RC Ladner, WN. Lipscomb; citation_volume=160; citation_publication_date=1982; citation_pages=219-263; citation_id=CR152

citation_journal_title=Cell; citation_title=Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis; citation_author=DJ Hosfield, Y Guan, BJ Haas, RP Cunningham, JA. Tainer; citation_volume=98; citation_publication_date=1999; citation_pages=397-408; citation_id=CR153

citation_journal_title=Nature; citation_title=High-resolution (1.5 Å) crystal structure of phospholipase C from Bacillus cereus ; citation_author=E Hough, LK Hansen, B Birknes, K Jynge, S Hansen, A Hordvik, C Little, E Dodson, Z. Derewenda; citation_volume=338; citation_publication_date=1989; citation_pages=357-360; citation_id=CR154

citation_journal_title=J Biol Chem; citation_title=Evidence for a catalytic role of zinc in protein farnesyltransferase. Spectroscopy of Co2+-farnesyltransferase indicates metal coordination of the substrate thiolate; citation_author=CC Huang, PJ Casey, CA. Fierke; citation_volume=272; citation_publication_date=1997; citation_pages=20-23; citation_id=CR155

citation_journal_title=J Mol Biol; citation_title=Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide; citation_author=S Huang, Y Xue, E Sauer-Eriksson, L Chirica, S Lindskog, BH. Jonsson; citation_volume=283; citation_publication_date=1998; citation_pages=301-310; citation_id=CR156

citation_journal_title=Science; citation_title=Identification and characterization of zinc binding sites in protein kinase C; citation_author=SR Hubbard, WR Bishop, P Kirschmeier, SJ George, SP Cramer, WA. Hendrickson; citation_volume=254; citation_publication_date=1991; citation_pages=1776-1179; citation_id=CR157

citation_journal_title=Biochemistry; citation_title=Metal binding specificity in carbonic anhydrase is influenced by conserved hydrophobic core residues; citation_author=JA Hunt, M Ahmed, CA. Fierke; citation_volume=38; citation_publication_date=1999; citation_pages=9054-9062; citation_id=CR158

citation_journal_title=Protein Sci; citation_title=Taxonomy and function of C1 protein kinase C homology domains; citation_author=JH Hurley, AC Newton, PJ Parker, PM Blumberg, Y. Nishizuka; citation_volume=6; citation_publication_date=1997; citation_pages=477-480; citation_id=CR159

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Structure of human beta 1 beta 1 alcohol dehydrogenase: catalytic effects of non-active-site substitutions; citation_author=TD Hurley, WF Bosron, JA Hamilton, LM. Amzel; citation_volume=88; citation_publication_date=1991; citation_pages=8149-8153; citation_id=CR160

citation_journal_title=J Mol Biol; citation_title=Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences; citation_author=TD Hurley, WF Bosron, CL Stone, LM. Amzel; citation_volume=239; citation_publication_date=1994; citation_pages=415-429; citation_id=CR161

citation_journal_title=Biochemistry; citation_title=A unique zincbinding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL; citation_author=SG Hymowitz, MP O'Connell, MH Ultsch, A Hurst, K Totpal, A Ashkenazi, AM de Vos, RF. Kelley; citation_volume=39; citation_publication_date=2000; citation_pages=633-640; citation_id=CR162

citation_journal_title=EMBO J; citation_title=Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia; citation_author=M Hyvonen, M. Saraste; citation_volume=16; citation_publication_date=1997; citation_pages=3396-3404; citation_id=CR163

citation_journal_title=J Biochem (Tokyo); citation_title=Solution structure of cysteine-rich domain of protein kinase C alpha; citation_author=S Ichikawa, H Hatanaka, Y Takeuchi, S Ohno, F. Inagaki; citation_volume=117; citation_publication_date=1995; citation_pages=566-574; citation_id=CR164

citation_journal_title=Biochemistry; citation_title=A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila ; citation_author=TM Iverson, BE Alber, C Kisker, JG Ferry, DC. Rees; citation_volume=39; citation_publication_date=2000; citation_pages=9222-9231; citation_id=CR165

citation_journal_title=J Biol Chem; citation_title=Novel zinc-containing ferredoxin family in thermoacidophilic archaea ; citation_author=T Iwasaki, T Suzuki, T Kon, T Imai, A Urushiyama, D Ohmori, T. Oshima; citation_volume=272; citation_publication_date=1997; citation_pages=3453-3458; citation_id=CR166

citation_journal_title=Acta Cryst D; citation_title=The porphobilinogen synthase family of metalloenzymes; citation_author=EK. Jaffe; citation_volume=56; citation_publication_date=2000; citation_pages=115-128; citation_id=CR167

citation_journal_title=J Mol Biol; citation_title=Structures of l-fuculose-1-phosphate aldolase mutants outlining motions during catalysis; citation_author=AC Joerger, C Mueller-Dieckmann, GE. Schulz; citation_volume=303; citation_publication_date=2000; citation_pages=531-543; citation_id=CR168

citation_journal_title=Alcohol Alcohol; citation_title=Nomenclature of alcohol dehydrogenases; citation_author=H Jornvall, JO. Hoog; citation_volume=30; citation_publication_date=1995; citation_pages=153-161; citation_id=CR169

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Mammalian alcohol dehydrogenases of separate classes: intermediates between different enzymes and intraclass isozymes; citation_author=H Jornvall, JO Hoog, H von Bahr-Lindstrom, BL. Vallee; citation_volume=84; citation_publication_date=1987; citation_pages=2580-2584; citation_id=CR170

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Crystal structure of human erythrocyte carbonic anhydrase B. Three-dimensional structure at a nominal 2.2-Å resolution; citation_author=KK Kannan, B Notstrand, K Fridborg, S Lovgren, A Ohlsson, M. Petef; citation_volume=72; citation_publication_date=1975; citation_pages=51-55; citation_id=CR171

citation_journal_title=Biochemistry; citation_title=Extended metal environments of cytochrome c oxidase structures; citation_author=S Karlin, ZY Zhu, KD. Karlin; citation_volume=37; citation_publication_date=1998; citation_pages=17726-17734; citation_id=CR172

citation_journal_title=J ExpMed; citation_title=Identification of HLA-DR1 beta chain residues critical for binding staphylococcal enterotoxins A and E; citation_author=DR Karp, EO. Long; citation_volume=175; citation_publication_date=1992; citation_pages=415-424; citation_id=CR173

citation_journal_title=Proc Natl Acad Sci USA; citation_title=The crystal structure of human interferon beta at 2.2-Å resolution; citation_author=M Karpusas, M Nolte, CB Benton, W Meier, WN Lipscomb, S. Goelz; citation_volume=94; citation_publication_date=1997; citation_pages=11813-11818; citation_id=CR174

citation_journal_title=J Mol Biol; citation_title=Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis; citation_author=EE Kim, HW. Wyckoff; citation_volume=218; citation_publication_date=1991; citation_pages=449-464; citation_id=CR175

citation_journal_title=Adv Enzymol Relat Areas Mol Biol; citation_title=Structure and mechanism of bovine lens leucine aminopeptidase; citation_author=H Kim, WN. Lipscomb; citation_volume=68; citation_publication_date=1994; citation_pages=153-213; citation_id=CR176

citation_journal_title=EMBO J; citation_title=The active site architecture of Pisum sativum beta-carbonic anhydrase is a mirror image of that of alpha-carbonic anhydrases; citation_author=MS Kimber, EF. Pai; citation_volume=19; citation_publication_date=2000; citation_pages=1407-1418; citation_id=CR177

citation_journal_title=EMBO J; citation_title=A lefthand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila ; citation_author=C Kisker, H Schindelin, BE Alber, JG Ferry, DC. Rees; citation_volume=15; citation_publication_date=1996; citation_pages=2323-2330; citation_id=CR178

citation_journal_title=Nature; citation_title=Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex; citation_author=CR Kissinger, HE Parge, DR Knighton, CT Lewis, LA Pelletier, A Tempczyk, VJ Kalish, KD Tucker, RE Showalter, EW Moomaw, LN Gastinel, N Habuka, X Chen, F Maldonado, JE Baker, R Bacquet, JE. Villefranco; citation_volume=378; citation_publication_date=1995; citation_pages=641-644; citation_id=CR179

citation_journal_title=J Biochem (Tokyo); citation_title=Three-dimensional structure of Cu,Zn-superoxide dismutase from spinach at 2.0 Å resolution; citation_author=Y Kitagawa, N Tanaka, Y Hata, M Kusunoki, GP Lee, Y Katsube, K Asada, S Aibara, Y. Morita; citation_volume=109; citation_publication_date=1991; citation_pages=477-485; citation_id=CR180

citation_journal_title=Structure and Bonding; citation_title=The dimetal centre in purple acid phosphatases; citation_author=T Klabunde, B. Krebs; citation_volume=89; citation_publication_date=1997; citation_pages=177-198; citation_id=CR181

citation_journal_title=J Mol Biol; citation_title=Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on crystal structures; citation_author=T Klabunde, N Strater, R Frohlich, H Witzel, B. Krebs; citation_volume=259; citation_publication_date=1996; citation_pages=737-748; citation_id=CR182

citation_journal_title=CRC Crit Rev Biochem; citation_title=Probes of mechanism and transition-state structure in the alcohol dehydrogenase reaction; citation_author=JP. Klinman; citation_volume=10; citation_publication_date=1981; citation_pages=39-78; citation_id=CR183

citation_journal_title=J Mol Biol; citation_title=Zinc finger peptides for the regulation of gene expression; citation_author=A. Klug; citation_volume=293; citation_publication_date=1999; citation_pages=215-218; citation_id=CR184

citation_journal_title=Nat Struct Biol; citation_title=X-ray structure of the Escherichia coli periplasmic 5'-nucleotidase containing a dimetal catalytic site; citation_author=T Knofel, N. Strater; citation_volume=6; citation_publication_date=1999; citation_pages=448-453; citation_id=CR185

citation_journal_title=Structure; citation_title=The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein; citation_author=TP Ko, CC Liao, WY Ku, KF Chak, HS. Yuan; citation_volume=7; citation_publication_date=1999; citation_pages=91-102; citation_id=CR186

citation_journal_title=J Mol Biol; citation_title=NADP-dependent bacterial alcohol dehydrogenases: crystal structure, cofactor-binding and cofactor specificity of the ADHs of Clostridium beijerinckii and Thermoanaerobacter brockii ; citation_author=Y Korkhin, AJ Kalb, M Peretz, O Bogin, Y Burstein, F. Frolow; citation_volume=278; citation_publication_date=1998; citation_pages=967-981; citation_id=CR187

citation_journal_title=J Mol Biol; citation_title=The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intrasubunit complementation during evolution; citation_author=IP Korndorfer, WD Fessner, BW. Matthews; citation_volume=300; citation_publication_date=2000; citation_pages=917-933; citation_id=CR188

citation_journal_title=J Biochem (Tokyo); citation_title=Crystal structure of H2-proteinase from the venom of Trimeresurus flavoviridis ; citation_author=T Kumasaka, M Yamamoto, H Moriyama, N Tanaka, M Sato, Y Katsube, Y Yamakawa, T Omori-Satoh, S Iwanaga, T. Ueki; citation_volume=119; citation_publication_date=1996; citation_pages=49-57; citation_id=CR189

citation_journal_title=J Biochem (Tokyo); citation_title=Structure of the zinc endoprotease from Streptomyces caespitosus ; citation_author=G Kurisu, T Kinoshita, A Sugimoto, A Nagara, Y Kai, N Kasai, S. Harada; citation_volume=121; citation_publication_date=1997; citation_pages=304-308; citation_id=CR190

citation_journal_title=J Mol Biol; citation_title=Sequence homology and structural analysis of the clostridial neurotoxins; citation_author=DB Lacy, RC. Stevens; citation_volume=291; citation_publication_date=1999; citation_pages=1091-1104; citation_id=CR191

citation_journal_title=Nat Struct Biol; citation_title=Crystal structure of botulinum neurotoxin type A and implications for toxicity; citation_author=DB Lacy, W Tepp, AC Cohen, BR DasGupta, RC. Stevens; citation_volume=5; citation_publication_date=1998; citation_pages=898-902; citation_id=CR192

citation_journal_title=Curr Opin Struct Biol; citation_title=Zinc finger proteins: new insights into structural and functional diversity; citation_author=JH Laity, BM Lee, PE. Wright; citation_volume=11; citation_publication_date=2001; citation_pages=39-46; citation_id=CR193

citation_journal_title=Structure; citation_title=The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein; citation_author=MC Lawrence, PA Pilling, VC Epa, AM Berry, AD Ogunniyi, JC. Paton; citation_volume=6; citation_publication_date=1998; citation_pages=1553-1561; citation_id=CR194

citation_journal_title=Biochemistry; citation_title=Control of coenzyme binding to horse liver alcohol dehydrogenase; citation_author=LA LeBrun, BV. Plapp; citation_volume=38; citation_publication_date=1999; citation_pages=12387-12393; citation_id=CR195

citation_journal_title=EMBO J; citation_title=Crystal structure of NAD(+)-dependent DNA ligase: modular architecture and functional implications; citation_author=JY Lee, C Chang, HK Song, J Moon, JK Yang, HK Kim, ST Kwon, SW. Suh; citation_volume=19; citation_publication_date=2000; citation_pages=1119-1129; citation_id=CR196

citation_journal_title=Nat Struct Biol; citation_title= Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone; citation_author=YH Lee, RK Deka, MV Norgard, JD Radolf, CA. Hasemann; citation_volume=6; citation_publication_date=1999; citation_pages=628-633; citation_id=CR197

citation_journal_title=Structure Fold Des; citation_title=Crystal structure of colicin E3 immunity protein: an inhibitor of a ribosome-inactivating RNase; citation_author=C Li, D Zhao, A Djebli, M. Shoham; citation_volume=7; citation_publication_date=1999; citation_pages=1365-1372; citation_id=CR198

citation_journal_title=J Biol Chem; citation_title=Crystal structures of zinc-free and-bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase; citation_author=H Li, CS Raman, CB Glaser, E Blasko, TA Young, JF Parkinson, M Whitlow, TL. Poulos; citation_volume=274; citation_publication_date=1999; citation_pages=21276-21284; citation_id=CR199

citation_journal_title=Biochemistry; citation_title=Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor; citation_author=YC Li, X Zhang, R Melton, V Ganu, NC. Gonnella; citation_volume=37; citation_publication_date=1998; citation_pages=14048-14056; citation_id=CR200

citation_journal_title=Protein Sci; citation_title=Structural consequences of the active site substitution Cys181 ⇒ Ser in metallo-betalactamase from Bacteroides fragilis ; citation_author=Z Li, BA Rasmussen, O. Herzberg; citation_volume=8; citation_publication_date=1999; citation_pages=249-252; citation_id=CR201

citation_journal_title=Nat New Biol; citation_title=Crystal structure of human carbonic anhydrase C; citation_author=A Liljas, KK Kannan, PC Bergsten, I Waara, K Fridborg, B Strandberg, U Carlbom, L Jarup, S Lovgren, M. Petef; citation_volume=235; citation_publication_date=1972; citation_pages=131-137; citation_id=CR202

citation_journal_title=Nature; citation_title=Instability and decay of the primary structure of DNA; citation_author=T. Lindahl; citation_volume=362; citation_publication_date=1993; citation_pages=709-715; citation_id=CR203

citation_journal_title=J Mol Biol; citation_title=Three-dimensional structure of a mammalian purple acid phosphatase at 2.2 Å resolution with a mu-(hydr)oxo bridged di-iron center; citation_author=Y Lindqvist, E Johansson, H Kaija, P Vihko, G. Schneider; citation_volume=291; citation_publication_date=1999; citation_pages=135-147; citation_id=CR204

citation_journal_title=Cur Opin Struct Biol; citation_title=Carbonic anhydrose and the role of orientation in catalysis; citation_author=S Lindskog, A. Liljas; citation_volume=3; citation_publication_date=1993; citation_pages=915-920; citation_id=CR205

citation_journal_title=Chem Rev; citation_title=Recent advances in zinc enzymology; citation_author=WN Lipscomb, N. Strater; citation_volume=96; citation_publication_date=1996; citation_pages=2375-2433; citation_id=CR206

citation_journal_title=Nature; citation_title=A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans; citation_author=L Liu, A Hausladen, M Zeng, L Que, J Heitman, JS. Stamler; citation_volume=410; citation_publication_date=2001; citation_pages=490-494; citation_id=CR207

citation_journal_title=Science; citation_title=Structure of human methionine aminopeptidase-2 complexed with fumagillin; citation_author=S Liu, J Widom, CW Kemp, CM Crews, J. Clardy; citation_volume=282; citation_publication_date=1998; citation_pages=1324-1327; citation_id=CR208

citation_journal_title=Cell; citation_title=The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site; citation_author=RA Love, HE Parge, JA Wickersham, Z Hostomsky, N Habuka, EW Moomaw, T Adachi, Z. Hostomska; citation_volume=87; citation_publication_date=1996; citation_pages=331-342; citation_id=CR209

citation_journal_title=Science; citation_title=Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor; citation_author=B Lovejoy, A Cleasby, AM Hassell, K Longley, MA Luther, D Weigl, G McGeehan, AB McElroy, D Drewry, MH Lambert, SR. Jordan; citation_volume=263; citation_publication_date=1994; citation_pages=375-377; citation_id=CR210

citation_journal_title=Biochemistry; citation_title=Crystal structures of recombinant 19-kDa human fibroblast collagenase complexed to itself; citation_author=B Lovejoy, AM Hassell, MA Luther, D Weigl, SR. Jordan; citation_volume=33; citation_publication_date=1994; citation_pages=8207-8217; citation_id=CR211

citation_journal_title=Nat Struct Biol; citation_title=Crystal structures of MMP-1 and-13 reveal the structural basis for selectivity of collagenase inhibitors; citation_author=B Lovejoy, AR Welch, S Carr, C Luong, C Broka, RT Hendricks, JA Campbell, KA Walker, R Martin, H Van Wart, MF. Browner; citation_volume=6; citation_publication_date=1999; citation_pages=217-221; citation_id=CR212

citation_journal_title=Biochemistry; citation_title=Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues; citation_author=WT Lowther, Y Zhang, PB Sampson, JF Honek, BW. Matthews; citation_volume=38; citation_publication_date=1999; citation_pages=14810-14819; citation_id=CR213

citation_journal_title=Trends Biochem Sci; citation_title=Zinc fingers are sticking together; citation_author=JP Mackay, M. Crossley; citation_volume=23; citation_publication_date=1998; citation_pages=1-4; citation_id=CR214

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum ; citation_author=CD Mackereth, CH Arrowsmith, AM Edwards, LP. McIntosh; citation_volume=97; citation_publication_date=2000; citation_pages=6316-6321; citation_id=CR215

citation_journal_title=FEBS Lett; citation_title=Crystal structure of Sglutathiolated carbonic anhydrase III; citation_author=RJ Mallis, BW Poland, TK Chatterjee, RA Fisher, S Darmawan, RB Honzatko, JA. Thomas; citation_volume=482; citation_publication_date=2000; citation_pages=237-241; citation_id=CR216

citation_journal_title=EMBO J; citation_title=Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta; citation_author=V Mandiyan, J Andreev, J Schlessinger, SR. Hubbard; citation_volume=18; citation_publication_date=1999; citation_pages=6890-6898; citation_id=CR217

citation_journal_title=Biochemistry; citation_title=Cobalt(II)-substituted class III alcohol and sorbitol dehydrogenases from human liver; citation_author=W. Maret; citation_volume=28; citation_publication_date=1989; citation_pages=9944-9949; citation_id=CR218

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Inhibitory sites in enzymes: zinc removal and reactivation by thionein; citation_author=W Maret, C Jacob, BL Vallee, EH. Fischer; citation_volume=96; citation_publication_date=1999; citation_pages=1936-1940; citation_id=CR219

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Thiolate ligands in metallothionein confer redox activity on zinc clusters; citation_author=W Maret, BL. Vallee; citation_volume=95; citation_publication_date=1998; citation_pages=3478-3482; citation_id=CR220

citation_journal_title=Biochemistry; citation_title=Influence of anions and pH on the conformational change of horse liver alcohol dehydrogenase induced by binding of oxidized nicotinamide adenine dinucleotide: binding of chloride to the catalytic metal ion; citation_author=W Maret, M. Zeppezauer; citation_volume=25; citation_publication_date=1986; citation_pages=1584-1588; citation_id=CR221

citation_journal_title=J Cell Biol; citation_title=Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells; citation_author=SM Mariani, B Matiba, EA Armandola, PH. Krammer; citation_volume=137; citation_publication_date=1997; citation_pages=221-229; citation_id=CR222

citation_journal_title=J Mol Biol; citation_title=Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ; citation_author=M Martinez-Yamout, GB Legge, O Zhang, PE Wright, HJ. Dyson; citation_volume=300; citation_publication_date=2000; citation_pages=805-818; citation_id=CR223

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme; citation_author=K Maskos, C Fernandez-Catalan, R Huber, GP Bourenkov, H Bartunik, GA Ellestad, P Reddy, MF Wolfson, CT Rauch, BJ Castner, R Davis, HR Clarke, M Petersen, JN Fitzner, DP Cerretti, CJ March, RJ Paxton, RA Black, W. Bode; citation_volume=95; citation_publication_date=1998; citation_pages=3408-3412; citation_id=CR224

citation_journal_title=Acc Chem Res; citation_title=Structural basis of the action of thermolysin and related zinc proteases; citation_author=BW. Matthews; citation_volume=21; citation_publication_date=1988; citation_pages=333-340; citation_id=CR225

citation_journal_title=J Biol Chem; citation_title=The conformation of thermolysin; citation_author=BW Matthews, LH Weaver, WR. Kester; citation_volume=249; citation_publication_date=1974; citation_pages=8030-8044; citation_id=CR226

citation_journal_title=J Mol Biol; citation_title=Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights speciesspecific features; citation_author=Y Mechulam, E Schmitt, L Maveyraud, C Zelwer, O Nureki, S Yokoyama, M Konno, S. Blanquet; citation_volume=294; citation_publication_date=1999; citation_pages=1287-1297; citation_id=CR227

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis; citation_author=JF Medina, A Wetterholm, O Radmark, R Shapiro, JZ Haeggstrom, BL Vallee, B. Samuelsson; citation_volume=88; citation_publication_date=1991; citation_pages=7620-7624; citation_id=CR228

citation_journal_title=J Biol Chem; citation_title=On the enzymatic activation of NADH; citation_author=R Meijers, RJ Morris, HW Adolph, A Merli, VS Lamzin, ES. Cedergren-Zeppezauer; citation_volume=276; citation_publication_date=2001; citation_pages=9316-9321; citation_id=CR229

citation_journal_title=J Mol Biol; citation_title=A new subclass of the zinc metalloproteases superfamily revealed by the solution structure of peptide deformylase; citation_author=T Meinnel, S Blanquet, F. Dardel; citation_volume=262; citation_publication_date=1996; citation_pages=375-386; citation_id=CR230

citation_journal_title=J Biol Chem; citation_title=X-ray structure of beta-carbonic anhydrase from the red alga, Porphyridium purpureum, reveals a novel catalytic site for CO(2) hydration; citation_author=S Mitsuhashi, T Mizushima, E Yamashita, M Yamamoto, T Kumasaka, H Moriyama, T Ueki, S Miyachi, T. Tsukihara; citation_volume=275; citation_publication_date=2000; citation_pages=5521-5526; citation_id=CR231

citation_journal_title=J Biochem (Tokyo); citation_title=Crystal structure of the unliganded alkaline protease from Pseudomonas aeruginosa IFO3080 and its conformational changes on ligand binding; citation_author=H Miyatake, Y Hata, T Fujii, K Hamada, K Morihara, Y. Katsube; citation_volume=118; citation_publication_date=1995; citation_pages=474-479; citation_id=CR232

citation_journal_title=Science; citation_title=Structure of human promatrix metalloproteinase-2: activation mechanism revealed [see comments]; citation_author=E Morgunova, A Tuuttila, U Bergmann, M Isupov, Y Lindqvist, G Schneider, K. Tryggvason; citation_volume=284; citation_publication_date=1999; citation_pages=1667-1670; citation_id=CR233

citation_journal_title=Proc Natl Acad Sci USA; citation_title=The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site; citation_author=HR Mott, JW Carpenter, S Zhong, S Ghosh, RM Bell, SL. Campbell; citation_volume=93; citation_publication_date=1996; citation_pages=8312-8317; citation_id=CR234

citation_journal_title=Biochemistry; citation_title=NMR solution structure of the catalytic fragment of human fibroblast collagenase complexed with a sulfonamide derivative of a hydroxamic acid compound; citation_author=FJ Moy, PK Chanda, JM Chen, S Cosmi, W Edris, JS Skotnicki, J Wilhelm, R. Powers; citation_volume=38; citation_publication_date=1999; citation_pages=7085-7096; citation_id=CR235

citation_journal_title=Biochemistry; citation_title=High-resolution solution structure of the inhibitor-free catalytic fragment of human fibroblast collagenase determined by multidimensional NMR; citation_author=FJ Moy, PK Chanda, S Cosmi, MR Pisano, C Urbano, J Wilhelm, R. Powers; citation_volume=37; citation_publication_date=1998; citation_pages=1495-1504; citation_id=CR236

citation_journal_title=Mol Cell; citation_title=Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin; citation_author=SW Muchmore, J Chen, C Jakob, D Zakula, ED Matayoshi, W Wu, H Zhang, F Li, SC Ng, DC. Altieri; citation_volume=6; citation_publication_date=2000; citation_pages=173-182; citation_id=CR237

citation_journal_title=Nat Struct Biol; citation_title=Trapping and visualization of a covalent enzyme-phosphate intermediate [letter]; citation_author=JE Murphy, B Stec, L Ma, ER. Kantrowitz; citation_volume=4; citation_publication_date=1997; citation_pages=618-622; citation_id=CR238

citation_journal_title=Chem Biol; citation_title=Metalcoordination sphere in the methylated Ada protein-DNA cocomplex; citation_author=LC Myers, TD Cushing, G Wagner, GL. Verdine; citation_volume=1; citation_publication_date=1994; citation_pages=91-97; citation_id=CR239

citation_journal_title=J Mol Biol; citation_title=Characterisation of the calcium-binding Cterminal domain of Clostridium perfringens alpha-toxin; citation_author=CE Naylor, M Jepson, DT Crane, RW Titball, J Miller, AK Basak, B. Bolgiano; citation_volume=294; citation_publication_date=1999; citation_pages=757-770; citation_id=CR240

citation_journal_title=Science; citation_title=Enzyme structure with two catalytic sites for double-sieve selection of substrate [see comments]; citation_author=O Nureki, DG Vassylyev, M Tateno, A Shimada, T Nakama, S Fukai, M Konno, TL Hendrickson, P Schimmel, S. Yokoyama; citation_volume=280; citation_publication_date=1998; citation_pages=578-582; citation_id=CR241

citation_journal_title=J Mol Biol; citation_title=Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon; citation_author=C Oefner, A D'Arcy, M Hennig, FK Winkler, GE. Dale; citation_volume=296; citation_publication_date=2000; citation_pages=341-349; citation_id=CR242

citation_journal_title=Biochemistry; citation_title=Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase; citation_author=NL Ogihara, HE Parge, PJ Hart, MS Weiss, JJ Goto, BR Crane, J Tsang, K Slater, JA Roe, JS Valentine, D Eisenberg, JA. Tainer; citation_volume=35; citation_publication_date=1996; citation_pages=2316-2321; citation_id=CR243

citation_journal_title=Structure; citation_title=Structure of the zinc-binding domain of Bacillus stearothermophilus DNA primase; citation_author=H Pan, DB. Wigley; citation_volume=8; citation_publication_date=2000; citation_pages=231-239; citation_id=CR244

citation_journal_title=Structure; citation_title=Superantigens as immunomodulators: recent structural insights; citation_author=AC Papageorgiou, KR. Acharya; citation_volume=5; citation_publication_date=1997; citation_pages=991-996; citation_id=CR245

citation_journal_title=Structure; citation_title=Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site; citation_author=AC Papageorgiou, KR Acharya, R Shapiro, EF Passalacqua, RD Brehm, HS. Tranter; citation_volume=3; citation_publication_date=1995; citation_pages=769-779; citation_id=CR246

citation_journal_title=EMBO J; citation_title=Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors; citation_author=AC Papageorgiou, CM Collins, DM Gutman, JB Kline, SM O'Brien, HS Tranter, KR. Acharya; citation_volume=18; citation_publication_date=1999; citation_pages=9-21; citation_id=CR247

citation_journal_title=Proc Nat Acad Sci USA; citation_title=Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase; citation_author=HE Parge, RA Hallewell, JA. Tainer; citation_volume=89; citation_publication_date=1992; citation_pages=6109-6113; citation_id=CR248

citation_journal_title=Science; citation_title=Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution [see comments]; citation_author=HW Park, SR Boduluri, JF Moomaw, PJ Casey, LS. Beese; citation_volume=275; citation_publication_date=1997; citation_pages=1800-1804; citation_id=CR249

citation_journal_title=J Biol Chem; citation_title=Mono-and binuclear Zn2+-beta-lactamase. Role of the conserved cysteine in the catalytic mechanism; citation_author=R Paul-Soto, R Bauer, JM Frere, M Galleni, W Meyer-Klaucke, H Nolting, GM Rossolini, D de Seny, M Hernandez-Valladares, M Zeppezauer, HW. Adolph; citation_volume=274; citation_publication_date=1999; citation_pages=13242-13249; citation_id=CR250

citation_journal_title=FEBS Lett; citation_title=Mono-and binuclear Zn-beta-lactamase from Bacteroides fragilis: catalytic and structural roles of the zinc ions; citation_author=R Paul-Soto, M Hernandez-Valladares, M Galleni, R Bauer, M Zeppezauer, JM Frere, HW. Adolph; citation_volume=438; citation_publication_date=1998; citation_pages=137-140; citation_id=CR251

citation_journal_title=J Mol Biol; citation_title=Crystal structure of neutral protease from Bacillus cereus refined at 3.0 Å resolution and comparison with the homologous but more thermostable enzyme thermolysin; citation_author=RA Pauptit, R Karlsson, D Picot, JA Jenkins, AS Niklaus-Reimer, JN. Jansonius; citation_volume=199; citation_publication_date=1988; citation_pages=525-537; citation_id=CR252

citation_journal_title=J Biol Chem; citation_title=Genetically engineered zinc-chelating adenylate kinase from Escherichia coli with enhanced thermal stability; citation_author=V Perrier, S Burlacu-Miron, S Bourgeois, WK Surewicz, AM. Gilles; citation_volume=273; citation_publication_date=1998; citation_pages=19097-19101; citation_id=CR253

citation_journal_title=Biochemistry; citation_title=Zinc chelation and structural stability of adenylate kinase from Bacillus subtilis ; citation_author=V Perrier, WK Surewicz, P Glaser, L Martineau, CT Craescu, H Fabian, HH Mantsch, O Barzu, AM. Gilles; citation_volume=33; citation_publication_date=1994; citation_pages=9960-9967; citation_id=CR254

citation_journal_title=J Mol Biol; citation_title=Functional and Crystallographic Characterization of Salmonella typhimurium Cu,Zn Superoxide Dismutase Coded by the sodCI Virulence Gene; citation_author=A Pesce, A Battistoni, ME Stroppolo, F Polizio, M Nardini, JS Kroll, PR Langford, P O'Neill, M Sette, A Desideri, M. Bolognesi; citation_volume=302; citation_publication_date=2000; citation_pages=465-478; citation_id=CR255

citation_journal_title=J Mol Biol; citation_title=Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography; citation_author=A Pesce, C Capasso, A Battistoni, S Folcarelli, G Rotilio, A Desideri, M. Bolognesi; citation_volume=274; citation_publication_date=1997; citation_pages=408-420; citation_id=CR256

citation_journal_title=EMBO J; citation_title=The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis; citation_author=JF Petersen, MM Cherney, HD Liebig, T Skern, E Kuechler, MN. James; citation_volume=18; citation_publication_date=1999; citation_pages=5463-5475; citation_id=CR257

citation_journal_title=J Virol; citation_title=vitro study of the NS2-3 protease of hepatitis C virus; citation_author=L Pieroni, E Santolini, C Fipaldini, L Pacini, G Migliaccio, N. LaMonica; citation_volume=71; citation_publication_date=1997; citation_pages=6373-6380; citation_id=CR258

citation_journal_title=J Mol Biol; citation_title=Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase; citation_author=T Ploom, B Thony, J Yim, S Lee, H Nar, W Leimbacher, J Richardson, R Huber, G. Auerbach; citation_volume=286; citation_publication_date=1999; citation_pages=851-860; citation_id=CR259

citation_journal_title=J BiolChem; citation_title=Structural insights into the protein splicing mechanism of PI-SceI; citation_author=BW Poland, MQ Xu, FA. Quiocho; citation_volume=275; citation_publication_date=2000; citation_pages=16408-16413; citation_id=CR260

citation_journal_title=Protein Sci; citation_title=Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity; citation_author=GS Prasad, R Radhakrishnan, DT Mitchell, CA Earhart, MM Dinges, WJ Cook, PM Schlievert, DH. Ohlendorf; citation_volume=6; citation_publication_date=1997; citation_pages=1220-1227; citation_id=CR261

citation_journal_title=J Exp Med; citation_title=Identification and characterization of novel superantigens from Streptococcus pyogenes ; citation_author=T Proft, SL Moffatt, CJ Berkahn, JD. Fraser; citation_volume=189; citation_publication_date=1999; citation_pages=89-102; citation_id=CR262

citation_journal_title=J Biol Chem; citation_title=The regulatory domain of protein kinase C coordinates four atoms of zinc; citation_author=AF Quest, J Bloomenthal, ES Bardes, RM. Bell; citation_volume=267; citation_publication_date=1992; citation_pages=10193-10197; citation_id=CR263

citation_journal_title=Adv Protein Chem; citation_title=Carboxypeptidase A: a protein and an enzyme; citation_author=FA Quiocho, WN. Lipscomb; citation_volume=25; citation_publication_date=1971; citation_pages=1-78; citation_id=CR264

citation_journal_title=EMBO J; citation_title=X-ray structure of T4 endonuclease VII: a DNA junction resolvase with a novel fold and unusual domain-swapped dimer architecture; citation_author=H Raaijmakers, O Vix, I Toro, S Golz, B Kemper, D. Suck; citation_volume=18; citation_publication_date=1999; citation_pages=1447-1458; citation_id=CR265

citation_journal_title=Structure; citation_title=Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography; citation_author=R Radhakrishnan, LJ Walter, A Hruza, P Reichert, PP Trotta, TL Nagabhushan, MR Walter; citation_volume=4; citation_publication_date=1996; citation_pages=1453-1463; citation_id=CR266

citation_journal_title=Cell; citation_title=Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center; citation_author=CS Raman, H Li, P Martasek, V Kral, BS Masters, TL. Poulos; citation_volume=95; citation_publication_date=1998; citation_pages=939-950; citation_id=CR267

citation_journal_title=Protein Sci; citation_title=Crystal structure of cod liver class I alcohol dehydrogenase: substrate pocket and structurally variable segments; citation_author=S Ramaswamy, M el Ahmad, O Danielsson, H Jornvall, H. Eklund; citation_volume=5; citation_publication_date=1996; citation_pages=663-671; citation_id=CR268

citation_journal_title=Eur J Immunol; citation_title=Immunochemical characterization of antigenic domains on human interferon-beta: spatially distinct epitopes are associated with both antiviral and antiproliferative activities; citation_author=PN Redlich, SE. Grossberg; citation_volume=20; citation_publication_date=1990; citation_pages=1933-1939; citation_id=CR269

citation_journal_title=JMol Biol; citation_title=Refined crystal structure of carboxypeptidase A at 1.54 Å resolution; citation_author=DC Rees, M Lewis, WN. Lipscomb; citation_volume=168; citation_publication_date=1983; citation_pages=367-387; citation_id=CR270

citation_journal_title=Nat Struct Biol; citation_title=Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2; citation_author=D Reverter, C Fernandez-Catalan, R Baumgartner, R Pfander, R Huber, W Bode, J Vendrell, TA Holak, FX. Aviles; citation_volume=7; citation_publication_date=2000; citation_pages=322-328; citation_id=CR271

citation_journal_title=J Biol Chem; citation_title=Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I; citation_author=M Ridderstrom, AD Cameron, TA Jones, B. Mannervik; citation_volume=273; citation_publication_date=1998; citation_pages=21623-21628; citation_id=CR272

citation_title=Metal-containing exopeptidases; citation_inbook_title=Food Related Enzymes; citation_publication_date=1974; citation_pages=220-240; citation_id=CR273; citation_author=JF. Riordan; citation_publisher=American Chemical Society

citation_journal_title=Biochemistry; citation_title=Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme; citation_author=SL Roderick, BW. M atthews; citation_volume=32; citation_publication_date=1993; citation_pages=3907-3912; citation_id=CR274

citation_journal_title=Nat Struct Biol; citation_title=Crystal structure of the streptococcal superantigen SPEC: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules; citation_author=A Roussel, BF Anderson, HM Baker, JD Fraser, EN. Baker; citation_volume=4; citation_publication_date=1997; citation_pages=635-643; citation_id=CR275

citation_journal_title=Biochemistry; citation_title=Kinetic and structural characterization of spinach carbonic anhydrase; citation_author=RS Rowlett, MR Chance, MD Wirt, DE Sidelinger, JR Royal, M Woodroffe, YF Wang, RP Saha, MG. Lam; citation_volume=33; citation_publication_date=1994; citation_pages=13967-13976; citation_id=CR276

citation_journal_title=Structure; citation_title=Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy; citation_author=S Rowsell, RA Pauptit, AD Tucker, RG Melton, DM Blow, P. Brick; citation_volume=5; citation_publication_date=1997; citation_pages=337-347; citation_id=CR277

citation_journal_title=Protein Sci; citation_title=On the role of Glu-68 in alcohol dehydrogenase; citation_author=U. Ryde; citation_volume=4; citation_publication_date=1995; citation_pages=1124-1132; citation_id=CR278

citation_journal_title=J Protein Chem; citation_title=Computational sequence analysis of matrix metalloproteinases; citation_author=QA Sang, DA. Douglas; citation_volume=15; citation_publication_date=1996; citation_pages=137-160; citation_id=CR279

citation_journal_title=Nat Struct Biol; citation_title=Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase [see comments]; citation_author=R Sankaranarayanan, AC Dock-Bregeon, B Rees, M Bovee, J Caillet, P Romby, CS Francklyn, D. Moras; citation_volume=7; citation_publication_date=2000; citation_pages=461-465; citation_id=CR280

citation_journal_title=Cell; citation_title=The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site; citation_author=R Sankaranarayanan, AC Dock-Bregeon, P Romby, J Caillet, M Springer, B Rees, C Ehresmann, B Ehresmann, D. Moras; citation_volume=97; citation_publication_date=1999; citation_pages=371-381; citation_id=CR281

citation_journal_title=J Mol Biol; citation_title=A structural and functional comparison of staphylococcal enterotoxins A and C2 reveals remarkable similarity and dissimilarity; citation_author=EM Schad, AC Papageorgiou, LA Svensson, KR. Acharya; citation_volume=269; citation_publication_date=1997; citation_pages=270-280; citation_id=CR282

citation_journal_title=EMBO J; citation_title=Crystal structure of the superantigen staphylococcal enterotoxin type A; citation_author=EM Schad, I Zaitseva, VN Zaitsev, M Dohlsten, T Kalland, PM Schlievert, DH Ohlendorf, LA. Svensson; citation_volume=14; citation_publication_date=1995; citation_pages=3292-3301; citation_id=CR283

citation_journal_title=Structure; citation_title=The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63); citation_author=E Schlagenhauf, R Etges, P. Metcalf; citation_volume=6; citation_publication_date=1998; citation_pages=1035-1046; citation_id=CR284

citation_journal_title=J Mol Biol; citation_title=Structure of carboxypeptidase B at 2-8 Å resolution; citation_author=MF Schmid, JR Herriott; citation_volume=103; citation_publication_date=1976; citation_pages=175-190; citation_id=CR285

citation_journal_title=J Biol Chem; citation_title=Octahedral metal coordination in the active site of glyoxalase I as evidenced by the properties of Co(II)-glyoxalase I; citation_author=S Sellin, LE Eriksson, AC Aronsson, B. Mannervik; citation_volume=258; citation_publication_date=1983; citation_pages=2091-2093; citation_id=CR286

citation_journal_title=J Biol Chem; citation_title=Metal dissociation constants for glyoxalase I reconstituted with Zn2+, Co2+, Mn2+, and Mg2+ ; citation_author=S Sellin, B. Mannervik; citation_volume=259; citation_publication_date=1984; citation_pages=11426-11429; citation_id=CR287

citation_journal_title=Biochemistry; citation_title=Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase; citation_author=V Sideraki, KA Mohamedali, DK Wilson, Z Chang, RE Kellems, FA Quiocho, FB. Rudolph; citation_volume=35; citation_publication_date=1996; citation_pages=7862-7872; citation_id=CR288

citation_journal_title=Acc Chem Res; citation_title=The catalytic mechanism of carbonic anhydrase: Implications of a rate limiting protolysis of water; citation_author=DN Silverman, S. Lindskog; citation_volume=21; citation_publication_date=1988; citation_pages=30-36; citation_id=CR289

citation_journal_title=Science; citation_title=Insights into editing from an iletRNA synthetase structure with tRNAile and mupirocin; citation_author=LF Silvian, J Wang, TA. Steitz; citation_volume=285; citation_publication_date=1999; citation_pages=1074-1077; citation_id=CR290

citation_journal_title=Eur J Biochem; citation_title=The affinity of human erythrocyte porphobilinogen synthase for Zn2+ and Pb2+ ; citation_author=TJ. Simons; citation_volume=234; citation_publication_date=1995; citation_pages=178-183; citation_id=CR291

citation_journal_title=FEMS Microbiol Rev; citation_title=Prokaryotic carbonic anhydrases; citation_author=KS Smith, JG. Ferry; citation_volume=24; citation_publication_date=2000; citation_pages=335-366; citation_id=CR292

citation_journal_title=Biochem Biophys Res Commun; citation_title=Zinc content of promatrilysin, matrilysin and the stromelysin catalytic domain; citation_author=D Soler, T Nomizu, WE Brown, M Chen, QZ Ye, HE Van Wart, DS. Auld; citation_volume=201; citation_publication_date=1994; citation_pages=917-923; citation_id=CR293

citation_journal_title=J Protein Chem; citation_title=Matrilysin: expression, purification, and characterization; citation_author=D Soler, T Nomizu, WE Brown, Y Shibata, DS. Auld; citation_volume=14; citation_publication_date=1995; citation_pages=511-520; citation_id=CR294

citation_journal_title=Nature; citation_title=The X-ray structure of a growth hormone-prolactin receptor complex [see comments]; citation_author=W Somers, M Ultsch, AM De Vos, AA. Kossiakoff; citation_volume=372; citation_publication_date=1994; citation_pages=478-481; citation_id=CR295

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a ‘cysteine switch’ mechanism for activation; citation_author=EB Springman, EL Angleton, H Birkedal-Hansen, HE. Van Wart; citation_volume=87; citation_publication_date=1990; citation_pages=364-368; citation_id=CR296

citation_journal_title=Cell; citation_title=Redox signaling: nitrosylation and related target interactions of nitric oxide; citation_author=JS. Stamler; citation_volume=78; citation_publication_date=1994; citation_pages=931-936; citation_id=CR297

citation_journal_title=Protein Sci; citation_title=Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination; citation_author=T Stams, Y Chen, PA Boriack-Sjodin, JD Hurt, J Liao, JA May, T Dean, P Laipis, DN Silverman, DW. Christianson; citation_volume=7; citation_publication_date=1998; citation_pages=556-563; citation_id=CR298

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Crystal structure of the secretory form of membraneassociated human carbonic anhydrase IV at 2.8-Å resolution; citation_author=T Stams, SK Nair, T Okuyama, A Waheed, WS Sly, DW. Christianson; citation_volume=93; citation_publication_date=1996; citation_pages=13589-13594; citation_id=CR299

citation_journal_title=J Mol Biol; citation_title=Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102; citation_author=B Stec, MJ Hehir, C Brennan, M Nolte, ER. Kantrowitz; citation_volume=277; citation_publication_date=1998; citation_pages=647-662; citation_id=CR300

citation_journal_title=J Mol Biol; citation_title=A revised mechanism for the alkaline phosphatase reaction involving three metal ions; citation_author=B Stec, KM Holtz, ER. Kantrowitz; citation_volume=299; citation_publication_date=2000; citation_pages=1303-1311; citation_id=CR301

citation_journal_title=Biochemistry; citation_title=Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease; citation_author=W Stocker, M Ng, DS. Auld; citation_volume=29; citation_publication_date=1990; citation_pages=10418-10425; citation_id=CR302

citation_journal_title=Biochemistry; citation_title=Astacus protease, a zinc metalloenzyme; citation_author=W Stocker, RL Wolz, R Zwilling, DJ Strydom, DS. Auld; citation_volume=27; citation_publication_date=1988; citation_pages=5026-5032; citation_id=CR303

citation_journal_title=Science; citation_title=Crystal structure of a purple acid phosphatase containing a dinuclear Fe(III)-Zn(II) active site; citation_author=N Strater, T Klabunde, P Tucker, H Witzel, B. Krebs; citation_volume=268; citation_publication_date=1995; citation_pages=1489-1492; citation_id=CR304

citation_journal_title=Biochemistry; citation_title=Transition state analogue Lleucinephosphonic acid bound to bovine lens leucine aminopeptidase: X-ray structure at 1.65 Å resolution in a new crystal form; citation_author=N Strater, WN. Lipscomb; citation_volume=34; citation_publication_date=1995; citation_pages=9200-9210; citation_id=CR305

citation_journal_title=Biochemistry; citation_title=Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue; citation_author=CL Strickland, WT Windsor, R Syto, L Wang, R Bond, Z Wu, J Schwartz, HV Le, LS Beese, PC. Weber; citation_volume=37; citation_publication_date=1998; citation_pages=16601-16611; citation_id=CR306

citation_journal_title=J Biol Chem; citation_title=Crystal structure of the ‘cab type’ beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum ; citation_author=P Strop, KS Smith, TM Iverson, JG Ferry, DC. Rees; citation_volume=276; citation_publication_date=2001; citation_pages=10299-10305; citation_id=CR307

citation_journal_title=EMBO J; citation_title=Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8; citation_author=M Sugahara, T Mikawa, T Kumasaka, M Yamamoto, R Kato, K Fukuyama, Y Inoue, S. Kuramitsu; citation_volume=19; citation_publication_date=2000; citation_pages=3857-3869; citation_id=CR308

citation_journal_title=Structure Fold Des; citation_title=The 2.0 Å crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules; citation_author=I Sugiura, O Nureki, Y Ugaji-Yoshikawa, S Kuwabara, A Shimada, M Tateno, B Lorber, R Giege, D Moras, S Yokoyama, M. Konno; citation_volume=8; citation_publication_date=2000; citation_pages=197-208; citation_id=CR309

citation_journal_title=EMBO J; citation_title=The crystal structure of staphylococcal enterotoxin type D reveals Zn2+-mediated homodimerization; citation_author=M Sundstrom, L Abrahmsen, P Antonsson, K Mehindate, W Mourad, M. Dohlsten; citation_volume=15; citation_publication_date=1996; citation_pages=6832-6840; citation_id=CR310

citation_journal_title=J Biol Chem; citation_title=The Co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 Å resolution. Implications for major histocompatibility complex class II binding; citation_author=M Sundstrom, D Hallen, A Svensson, E Schad, M Dohlsten, L. Abrahmsen; citation_volume=271; citation_publication_date=1996; citation_pages=32212-32216; citation_id=CR311

citation_journal_title=J Mol Biol; citation_title=Crystal Structures of mouse class II alcohol dehydrogenase reveal determinants of substrate specificity and catalytic efficiency; citation_author=S Svensson, JO Hoog, G Schneider, T. Sandalova; citation_volume=302; citation_publication_date=2000; citation_pages=441-453; citation_id=CR312

citation_journal_title=Nat Struct Biol; citation_title=Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B [see comments]; citation_author=S Swaminathan, S. Eswaramoorthy; citation_volume=7; citation_publication_date=2000; citation_pages=693-699; citation_id=CR313

citation_journal_title=J Struct Biol; citation_title=High-resolution crystals of methionine aminopeptidase from Pyrococcus furiosus obtained by water-mediated transformation; citation_author=TH Tahirov, H Oki, T Tsukihara, K Ogasahara, K Yutani, CP Libeu, Y Izu, S Tsunasawa, I. Kato; citation_volume=121; citation_publication_date=1998; citation_pages=68-72; citation_id=CR314

citation_journal_title=J Mol Biol; citation_title=Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus ; citation_author=TH Tahirov, H Oki, T Tsukihara, K Ogasahara, K Yutani, K Ogata, Y Izu, S Tsunasawa, I. Kato; citation_volume=284; citation_publication_date=1998; citation_pages=101-124; citation_id=CR315

citation_journal_title=J Mol Biol; citation_title=Determination and analysis of the 2 Å-structure of copper, zinc superoxide dismutase; citation_author=JA Tainer, ED Getzoff, KM Beem, JS Richardson, DC. Richardson; citation_volume=160; citation_publication_date=1982; citation_pages=181-217; citation_id=CR316

citation_journal_title=FASEB J; citation_title=Aminopeptidases: structure and function; citation_author=A. Taylor; citation_volume=7; citation_publication_date=1993; citation_pages=290-298; citation_id=CR317

citation_journal_title=Eur J Biochem; citation_title=Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris ; citation_author=A Teplyakov, K Polyakov, G Obmolova, B Strokopytov, I Kuranova, A Osterman, N Grishin, S Smulevitch, O Zagnitko, O Galperina, M Matz, V. Stepanov; citation_volume=208; citation_publication_date=1992; citation_pages=281-288; citation_id=CR318

citation_journal_title=J Biol Chem; citation_title=Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-Å resolution; citation_author=MM Thayer, KM Flaherty, DB. McKay; citation_volume=266; citation_publication_date=1991; citation_pages=2864-2871; citation_id=CR319

citation_journal_title=Biochemistry; citation_title=Structural analysis of the H166G site-directed mutant of galactose-1-phosphate uridylyltransferase complexed with either UDP-glucose or UDP-galactose: detailed description of the nucleotide sugar binding site; citation_author=JB Thoden, FJ Ruzicka, PA Frey, I Rayment, HM. Holden; citation_volume=36; citation_publication_date=1997; citation_pages=1212-1222; citation_id=CR320

citation_journal_title=Nat Struct Biol; citation_title=Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation; citation_author=MM Thunnissen, P Nordlund, JZ. Haeggstrom; citation_volume=8; citation_publication_date=2001; citation_pages=131-135; citation_id=CR321

citation_journal_title=Mol Cell; citation_title=Crystallographic and functional studies of very short patch repair endonuclease; citation_author=SE Tsutakawa, T Muto, T Kawate, H Jingami, N Kunishima, M Ariyoshi, D Kohda, M Nakagawa, K. Morikawa; citation_volume=3; citation_publication_date=1999; citation_pages=621-628; citation_id=CR322

citation_journal_title=J Mol Biol; citation_title=The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 Å resolution; citation_author=JH Ullah, TR Walsh, IA Taylor, DC Emery, CS Verma, SJ Gamblin, J. Spencer; citation_volume=284; citation_publication_date=1998; citation_pages=125-136; citation_id=CR323

citation_journal_title=J Mol Biol; citation_title=Crystal structure of a mammalian purple acid phosphatase; citation_author=J Uppenberg, F Lindqvist, C Svensson, B Ek-Rylander, G. Andersson; citation_volume=290; citation_publication_date=1999; citation_pages=201-211; citation_id=CR324

citation_journal_title=J Biol Chem; citation_title=The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation; citation_author=A Urbani, R Bazzo, MC Nardi, DO Cicero, R De Francesco, C Steinkuhler, G. Barbato; citation_volume=273; citation_publication_date=1998; citation_pages=18760-18769; citation_id=CR325

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Active-site zinc ligands and activated H2O of zinc enzymes; citation_author=BL Vallee, DS. Auld; citation_volume=87; citation_publication_date=1990; citation_pages=220-224; citation_id=CR326

citation_journal_title=Biochemistry; citation_title=Zinc coordination, function, and structure of zinc enzymes and other proteins; citation_author=BL Vallee, DS. Auld; citation_volume=29; citation_publication_date=1990; citation_pages=5647-5659; citation_id=CR327

citation_journal_title=Matrix Suppl; citation_title=Active zinc binding sites of zinc metalloenzymes; citation_author=BL Vallee, DS. Auld; citation_volume=1; citation_publication_date=1992; citation_pages=5-19; citation_id=CR328

citation_journal_title=Faraday Discuss; citation_title=Functional zinc-binding motifs in enzymes and DNA-binding proteins; citation_author=BL Vallee, DS. Auld; citation_volume=93; citation_publication_date=1992; citation_pages=47-65; citation_id=CR329

citation_journal_title=Biochemistry; citation_title=New perspective on zinc biochemistry: cocatalytic sites in multi-zinc enzymes; citation_author=BL Vallee, DS. Auld; citation_volume=32; citation_publication_date=1993; citation_pages=6493-6500; citation_id=CR330

citation_journal_title=Acc Chem Res; citation_title=Zinc: Biological Functions and Coordination Motifs; citation_author=BL Vallee, DS. Auld; citation_volume=26; citation_publication_date=1993; citation_pages=543-551; citation_id=CR331

citation_journal_title=Proc Natl Acad Sci USA; citation_title=Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains; citation_author=BL Vallee, JE Coleman, DS. Auld; citation_volume=88; citation_publication_date=1991; citation_pages=999-1003; citation_id=CR332

citation_journal_title=Physiol Rev; citation_title=The biochemical basis of zinc physiology; citation_author=BL Vallee, KH. Falchuk; citation_volume=73; citation_publication_date=1993; citation_pages=79-118; citation_id=CR333

citation_journal_title=Adv Enzymol Relat Areas Mol Biol; citation_title=The metallobiochemistry of zinc enzymes; citation_author=BL Vallee, A. Galdes; citation_volume=56; citation_publication_date=1984; citation_pages=283-430; citation_id=CR334

citation_journal_title=Protein Sci; citation_title=Solution structure of the catalytic domain of human stromelysin complexed with a hydrophobic inhibitor; citation_author=SR Van Doren, AV Kurochkin, W Hu, QZ Ye, LL Johnson, DJ Hupe, ER. Zuiderweg; citation_volume=4; citation_publication_date=1995; citation_pages=2487-2498; citation_id=CR335

citation_journal_title=Biochemistry; citation_title=Three-dimensional structure of the zinc-containing phosphotriesterase with the bound substrate analog diethyl 4-methylbenzylphosphonate; citation_author=JL Vanhooke, MM Benning, FM Raushel, HM. Holden; citation_volume=35; citation_publication_date=1996; citation_pages=6020-6025; citation_id=CR336

citation_journal_title=Nat Struct Biol; citation_title=Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement [see comments]; citation_author=MA Verdecia, H Huang, E Dutil, DA Kaiser, T Hunter, JP. Noel; citation_volume=7; citation_publication_date=2000; citation_pages=602-608; citation_id=CR337

citation_journal_title=EMBO J; citation_title=Crystal structure of Penicillium citrinum P1 nuclease at 2.8 Å resolution; citation_author=A Volbeda, A Lahm, F Sakiyama, D. Suck; citation_volume=10; citation_publication_date=1991; citation_pages=1607-1618; citation_id=CR338

citation_journal_title=Protein Sci; citation_title=Yeast methionine aminopeptidase I can utilize either Zn2+ or Co2+ as a cofactor: a case of mistaken identity?; citation_author=KW Walker, RA. Bradshaw; citation_volume=7; citation_publication_date=1998; citation_pages=2684-2687; citation_id=CR339

citation_journal_title=Structure; citation_title=High-resolution structure of an archaeal zinc ribbon defines a general architectural motif in eukaryotic RNA polymerases; citation_author=B Wang, DN Jones, BP Kaine, MA. Weiss; citation_volume=6; citation_publication_date=1998; citation_pages=555-569; citation_id=CR340

citation_journal_title=Biochemistry; citation_title=Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity; citation_author=Z Wang, FA. Quiocho; citation_volume=37; citation_publication_date=1998; citation_pages=8314-8324; citation_id=CR341

citation_journal_title=Proteins Struc Funct Genet; citation_title=A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 Å Streptomyces rubiginosus structures with xylitol and D-Xylose; citation_author=M Whitlow, AJ Howard, BC Finzel, TL Poulos, E Winborne, GL. Gilliland; citation_volume=9; citation_publication_date=1991; citation_pages=153-173; citation_id=CR342

citation_journal_title=Biochemistry; citation_title=A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water; citation_author=DK Wilson, FA. Quiocho; citation_volume=32; citation_publication_date=1993; citation_pages=1689-1694; citation_id=CR343

citation_journal_title=Science; citation_title=Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations; citation_author=DK Wilson, FB Rudolph, FA. Quiocho; citation_volume=252; citation_publication_date=1991; citation_pages=1278-1284; citation_id=CR344

citation_journal_title=Nature; citation_title=Structure of the 30S ribosomal subunit [see comments]; citation_author=BT Wimberly, DE Brodersen, W. J. Clemons, RJ Morgan-Warren, AP Carter, C Vonrhein, T Hartsch, V. Ramakrishnan; citation_volume=407; citation_publication_date=2000; citation_pages=327-339; citation_id=CR345

citation_journal_title=Biochemistry; citation_title=Transitionstate selectivity for a single hydroxyl group during catalysis by cytidine deaminase; citation_author=S Xiang, SA Short, R Wolfenden, CW Carter; citation_volume=34; citation_publication_date=1995; citation_pages=4516-4523; citation_id=CR346

citation_journal_title=J Biol Chem; citation_title=X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity; citation_author=P Xie, SH Parsons, DC Speckhard, WF Bosron, TD. Hurley; citation_volume=272; citation_publication_date=1997; citation_pages=18558-18563; citation_id=CR347

citation_journal_title=Protein Sci; citation_title=Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 Å resolution structure in a hexagonal crystal form; citation_author=Y Yan, Y Li, S Munshi, V Sardana, JL Cole, M Sardana, C Steinkuehler, L Tomei, R De Francesco, LC Kuo, Z. Chen; citation_volume=7; citation_publication_date=1998; citation_pages=837-847; citation_id=CR348

citation_journal_title=J Biol Chem; citation_title=Kinetic properties and metal content of the metallo-beta-lactamase CcrA harboring selective amino acid substitutions; citation_author=Y Yang, D Keeney, X Tang, N Canfield, BA. Rasmussen; citation_volume=274; citation_publication_date=1999; citation_pages=15706-15711; citation_id=CR349

citation_journal_title=J Mol Biol; citation_title=Structure of human chi chi alcohol dehydrogenase: a glutathione-dependent formaldehyde dehydrogenase; citation_author=ZN Yang, WF Bosron, TD. Hurley; citation_volume=265; citation_publication_date=1997; citation_pages=330-343; citation_id=CR350

citation_title=Crystal structure of a thermophilic cytochrome P450 from the archaeon ; citation_inbook_title=J Biol Chem; citation_publication_date=2000; citation_pages=31086-31092; citation_id=CR351; citation_author=JK Yano; citation_author=LS Koo; citation_author=DJ Schuller; citation_author=H Li; citation_publisher=Ortiz De Montellano PR

citation_journal_title=EMBO J; citation_title=Crystal structure of a eukaryote/archaeon-like prolyl-tRNA synthetase and its complex with tRNA(Pro)(CGG); citation_author=A Yaremchuk, S Cusack, M. Tukalo; citation_volume=19; citation_publication_date=2000; citation_pages=4745-4758; citation_id=CR352

citation_journal_title=Ann Rev Biochem; citation_title=Protein prenylation: molecular mechanisms and functional consequences; citation_author=FL Zhang, PJ. Casey; citation_volume=65; citation_publication_date=1996; citation_pages=241-269; citation_id=CR353

citation_journal_title=Cell; citation_title=Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 Å resolution [see comments]; citation_author=G Zhang, EA Campbell, L Minakhin, C Richter, K Severinov, SA. Darst; citation_volume=98; citation_publication_date=1999; citation_pages=811-824; citation_id=CR354

citation_journal_title=Cell; citation_title=Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester; citation_author=G Zhang, MG Kazanietz, PM Blumberg, JH. Hurley; citation_volume=81; citation_publication_date=1995; citation_pages=917-924; citation_id=CR355

citation_journal_title=Structure; citation_title=Crystal structure of Rab geranylgeranyltransferase at 2.0 Å resolution; citation_author=H Zhang, MC Seabra, J. Deisenhofer; citation_volume=8; citation_publication_date=2000; citation_pages=241-251; citation_id=CR356

citation_journal_title=Acta Crystallogr D Biol Cryst; citation_title=Structure of acutolysin-C, a haemorrhagic toxin from the venom of Agkistrodon acutus, providing further evidence for the mechanism of the pH-dependent proteolytic reaction of zinc metalloproteinases; citation_author=X Zhu, M Teng, L. Niu; citation_volume=55; citation_publication_date=1999; citation_pages=1834-1841; citation_id=CR357