Zervikoviszerale Resektionen beim organüberschreitenden Schilddrüsenkarzinom

Springer Science and Business Media LLC - Tập 80 - Trang 88-98 - 2009
M. Brauckhoff1, H. Dralle2
1Department of Surgery, Haukeland University Hospital, University of Bergen, Bergen, Norway
2Klinik für Allgemein Viszeral- und Gefäßchirurgie, Universitätsklinikum Halle, Halle, Deutschland

Tóm tắt

Etwa 6% aller Patienten mit Schilddrϋsenkarzinom weisen eine potenziell vital bedrohliche Tumorinvasion in Trachea und/oder Ösophagus auf. Das Resektionsausmaß richtet sich nach Tumordiagnose und -stadium (Indikation nur bei differenzierten und ggf. medullären Schilddrüsenkarzinomen ohne extrapulmonale Fernmetastasen), aerodigestivem Invasionsausmaß und Allgemeinzustand der Patienten. Mit R0-Resektionen sind 5- bzw. 10-Jahres-Überlebensraten von 40–75% erreichbar. Inkomplette Resektionen verschlechtern die Prognose. Tangentiale Tumorresektionen („shaving“) sind bei nichttransmuraler Tumorinvasion mit guten Langzeitresultaten möglich. Bei den trachealen Resektionsverfahren werden in Abhängigkeit von Tumorlokalisation und -ausdehnung 6 Standardresektionen unterschieden (Typ 1 und 2: Fensterung des laryngotrachealen Winkels bzw. der Trachea; Typ 3 und 4: zirkuläre Resektionen mit Anastomose subglottisch bzw. tracheal; Typ 5 und 6: Laryngektomie bzw. zervikale Eviszeration).

Tài liệu tham khảo

Bayles SW, Kingdom TT, Carlson GW (1998) Management of thyroid carcinoma invading the aerodigestive tract. Laryngoscope 108:1402–1407 Brauckhoff M, Meinicke A, Bilkenroth U et al (2006) Long-term results and functional outcome after cervical evisceration in patients with thyroid cancer. Surgery 140:953–995 Czaja JM, McCaffrey TV (1997) The surgical management of laryngotracheal invasion by well-differentiated papillary thyroid carcinoma. Arch Otolaryngol Head Neck Surg 123:484–490 Dralle H, Brauckhoff M, Machens A, Gimm O (2005) Surgical management of advanced thyroid cancer invading the aerogigestive tract. In: Clark OH, Duh QY, Kebebew E (eds) Textbook on endocrine surgery. 2nd edn. Philadelphia: Elsevier Saunders pp 318–333 Dralle H, Scheumann GFW, Meyer HJ et al (1992) Cervical procedure at the aerodigestive tract in advanced thyroid cancer. Chirurg 63:282–290 Dralle H, Scheumann GFW (1993) Cervicovisceral reconstruction after resection of locally advanced thyroid carcinoma. Langenbecks Arch Chir [Suppl]:486–489 Farahati J, Reiners C, Stuschke M et al (1996) Differentiated thyroid cancer – impact of adjuvant external radiotherapy in patients with perithyroidal tumor infiltration (stage pT4). Cancer 77:172–180 Friedmann M, Danielzadeh JA, Caldarelli DD (1994) Treatment of patients with carcinoma of the thyroid invading the airway. Arch Otolaryngol Head Neck Surg 120:1377–1381 Fujimoto Y, Obara T, Ito Y et al (1986) Aggressive surgical approach for locally invasive papillary carcinoma of the thyroid in patients over forty-five years of age. Surgery 100:1098–1107 Gaissert HA, Honings J, Grillo HC et al (2007) Segmental laryngotracheal and tracheal resection for invasive thyroid carcinoma. Ann Thorac Surg 83:1952–1959 Grillo HC, Suen HC, Mathisen DJ, Wain JC (1992) Resectional management of thyroid carcinoma invading the airway. Ann Thorac Surg 54:3–10 Hanna E, Sherman A, Cash D et al (2004) Quality of life for patients following total laryngectomy vs chemoradiation for laryngeal preservation. Arch Otolaryngol Head Neck Surg 130:875–879 Hundahl SA, Fleming ID, Fremgen AM, Menck HR (1998) A national cancer data base report on 53,856 cases of thyroid carcinoma treated in the U S 1985–1995. Cancer 83:2638–2648 Ishihara T, Kobayashi K, Kikuchi K et al (1991) Surgical treatment of advanced thyroid carcinoma invading the trachea. J Thorac Cardiovasc Surg 102:717–720 Kim KH, Sung MW, Chang KH, Kang BS (2000) Therapeutic dilemmas in the management of thyroid cancer with laryngotracheal involvement. Otolaryngol Head Neck Surg 122:763–767 Kitamura Y, Shimizu K, Nagahama M et al (1999) Immediate causes of death in thyroid carcinoma: clinicopathological analysis of 161 fatal cases. J Clin Endocrinol Metab 84:4043–4048 Lang BH, Lo CY, Chan WF et al (2007) Prognostic factors in papillary and follicular thyroid carcinoma: their implications for cancer staging. Ann Surg Oncol 14:730–738 Lipton RJ, McCaffrey T, Heerden J van (1987) Surgical treatment of invasion of the upper aerodigestive tract by well-differentiated thyroid carcinoma. Am J Surg 154:363–367 Machens A, Hinze R, Lautenschläger C et al (2001) Thyroid carcinoma invading the cervicovisceral axis: routes of invasion and clinical implications. Surgery 129:23–28 Machens A, Hinze R, Dralle H (2001) Surgery on the cervicovisceral axis for invasive thyroid cancer. Langenbecks Arch Surg 386:318–323 Machens A, Hofmann C, Hauptmann S, Dralle H (2007) Locoregional recurrence and death from medullary thyroid carcinoma in a contemporaneous series: 5-year results. Eur J Endocrinol 157:85–93 McCaffrey TV, Bergstralh EJ, Hay ID (1994) Locally invasive papillary thyroid carcinoma: 1940–1990. Head Neck 4:165–172 Mellière DJM, Yahia NEB, Becquemin JP et al (1993) Thyroid carcinoma with tracheal or esophageal involvement: limited or maximal surgery? Surgery 113:166–172 Musholt TJ, Musholt PB, Behrend M et al (1999) Invasive differentiated thyroid carcinoma: tracheal resection and reconstruction procedures in the hands of the endocrine surgeon. Surgery 126:1078–1088 Nakao K, Kurozumi K, Fukushima S et al (2001) Merits and demerits of operative procedure to the trachea in patients with differentiated thyroid cancer. Word J Surg 25:723–727 Nishida T, Nakao K, Hamaji M (1997) Differentiated thyroid carcinoma with airway invasions: indikation for tracheal resection based on the extent of cancer invasion. J Thoracic Cardiovasc Surg 114:84–92 Nomori H, Kobayashi K, Ishihara T et al (1990) Thyroid carcinoma infiltrating the trachea: clinical, histologic and morphometric analyses. J Surg Oncol 44:78–83 Ozaki O, Sugino K, Mimura T, Ito K (1995) Surgery for patients with thyroid carcinoma invading the trachea: circumferential sleeve resection followed by end-to-end anastomosis. Surgery 117:268–271 Robbins RJ, Wan Q, Grewal RK et al (2006) Real-time prognosis for metastatic thyroid carcinoma based on 2-[18F] fluoro-2-deoxy-D-glucose-positron emission tomography scanning. J Clin Endocrinol Metab 91:498–505 Salassa JR, Pearson BW, Payne WS (1977) Gross and microscopical blood supply of the trachea. Ann Thorac Surg 24:100–107 Sawka AM, Thephamongkhol K, Brouwers M et al (2004) Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer. J Clin Endocrinol Metab 89:3668–3676 Schlumberger M, Tubiana M, Vathaire de F et al (1986) Long-term results of treatment of 283 patients with lung and bone metastases from differentiated thyroid carcinoma. J Clin Endocrinol Metab 63:960–967 Segal K, Shpitzer T, Hazan A et al (2006) Invasive well-differentiated thyroid carcinoma: effect of treatment modalities on outcome. Otolaryngol Head Neck Surg 134:819–822 Shin DH, Mark EJ, Suen HC, Grillo HC (1993) Pathologic staging of papillary carcinoma of the thyroid with airway invasion based on the anatomic manner of extension to the trachea: a clinicopathologic study based on 22 patients who underwent thyroidectomy and airway resection. Hum Pathol 24:866–870 Tsai YF, Tseng YL, Wu MH et al (2005) Aggressive resection of the airway invaded by thyroid carcinoma. Br J Surg 92:1382–1387 Tsumori T, Nakao K, Miyata M et al (1985) Clinicopathologic study of thyroid carcinoma infiltrating the trachea. Cancer 56:2843–2848 Wu HS, Young MT, Ituarte PH et al (2000) Death from thyroid cancer of follicular cell origin. J Am Coll Surg 191:600–606