ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses

Biomaterials Science - Tập 8 Số 11 - Trang 3147-3163
Junxiong Qiu1,2,3,4,5, Peng Peng1,2,4,6,5, Xin Min1,7,5,8, Zhenkang Wen1,2,4,6,5, Chen Zhong1,2,4,6,5, Sipeng Lin1,2,4,6,5, Manyuan Kuang1,2,4,6,5, Yuan Fu1,2,4,6,5, Guibin Fang1,2,4,6,5, Shixun Li1,2,4,6,5, Changchuan Li1,2,4,6,5, Jiaji Mao1,9,4,6,5, Ling Qin10,11,12, Yue Ding1,2,4,6,5
1China
2Department of Orthopaedic Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China
4Guangzhou 510120
5Sun Yat-sen University
6Sun Yat-Sen Memorial Hospital;
7Guangzhou 510000
8Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510000, China
9Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China
10Musculoskeletal Research Laboratory Department of Orthopaedics & Taumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory of Li Ka Shing Institute of Health Sciences, the Chinese University of Hong Kong, SAR, PR China
11PR China
12The Chinese University of Hong Kong

Tóm tắt

Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.

Từ khóa


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Biomaterials Science

Tập 8 Số 11

3147-3163

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