YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
Ramalho-Santos, 2002, “Stemness”: transcriptional profiling of embryonic and adult stem cells, Science, 298, 597, 10.1126/science.1072530
Huang, 2005, The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP, Cell, 122, 421, 10.1016/j.cell.2005.06.007
Tapon, 2002, salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines, Cell, 110, 467, 10.1016/S0092-8674(02)00824-3
McClatchey, 2005, Membrane organization and tumorigenesis—the NF2 tumor suppressor Merlin, Genes Dev., 19, 2265, 10.1101/gad.1335605
St John, 1999, Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction, Nat. Genet., 21, 182, 10.1038/5965
Overholtzer, 2006, Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon, Proc. Natl. Acad. Sci. USA, 103, 12405, 10.1073/pnas.0605579103
Zender, 2006, Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach, Cell, 125, 1253, 10.1016/j.cell.2006.05.030
Beard, 2006, Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells, Genesis, 44, 23, 10.1002/gene.20180
Basu, 2003, Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis, Mol. Cell, 11, 11, 10.1016/S1097-2765(02)00776-1
Kistner, 1996, Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice, Proc. Natl. Acad. Sci. USA, 93, 10933, 10.1073/pnas.93.20.10933
Stanger, 2005, Pten constrains centroacinar cell expansion and malignant transformation in the pancreas, Cancer Cell, 8, 185, 10.1016/j.ccr.2005.07.015
Stanger, 2006, Dissecting the cellular origins of pancreatic cancer, Cell Cycle, 5, 43, 10.4161/cc.5.1.2291
Jensen, 2000, Control of endodermal endocrine development by Hes-1, Nat. Genet., 24, 36, 10.1038/71657
Louvard, 1992, The differentiating intestinal epithelial cell: establishment and maintenance of functions through interactions between cellular structures, Annu. Rev. Cell Biol., 8, 157, 10.1146/annurev.cb.08.110192.001105
Hochedlinger, 2005, Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues, Cell, 121, 465, 10.1016/j.cell.2005.02.018
Clevers, 2006, Wnt/beta-catenin signaling in development and disease, Cell, 127, 469, 10.1016/j.cell.2006.10.018
Batlle, 2002, Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB, Cell, 111, 251, 10.1016/S0092-8674(02)01015-2
Andreu, 2005, Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine, Development, 132, 1443, 10.1242/dev.01700
Sansom, 2004, Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration, Genes Dev., 18, 1385, 10.1101/gad.287404
Crosnier, 2006, Organizing cell renewal in the intestine: stem cells, signals and combinatorial control, Nat. Rev. Genet., 7, 349, 10.1038/nrg1840
van Es, 2005, Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells, Nature, 435, 959, 10.1038/nature03659
Milano, 2004, Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation, Toxicol. Sci., 82, 341, 10.1093/toxsci/kfh254