Xiaotan Sanjie recipe, a compound Chinese herbal medicine, inhibits gastric cancer metastasis by regulating GnT-V-mediated E-cadherin glycosylation

Foster, 2023, The contemporary management of peritoneal metastasis: a journey from the cold past of treatment futility to a warm present and a bright future, CA Cancer J Clin, 73, 49, 10.3322/caac.21749 Ilic, 2022, Epidemiology of stomach cancer, World J Gastroenterol, 28, 1187, 10.3748/wjg.v28.i12.1187 Li, 2022, Surgical management of gastric cancer: a review, JAMASurg, 157, 446 Mocan, 2021, Surgical management of gastric cancer: a systematic review, J Clin Med, 10, 2557, 10.3390/jcm10122557 Lei, 2022, Signaling pathways and therapeutic interventions in gastric cancer, Signal Transduct Target Ther, 7, 358, 10.1038/s41392-022-01190-w Joshi, 2021, Current treatment and recent progress in gastric cancer, CA Cancer J Clin, 71, 264, 10.3322/caac.21657 Lordick, 2022, Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up, Ann Oncol, 33, 1005, 10.1016/j.annonc.2022.07.004 Huang, 2022, An approach to the primary and secondary prevention of gastric cancer in the United States, Clin Gastroenterol Hepatol, 20, 2218, 10.1016/j.cgh.2021.09.039 Smyth, 2020, Gastric cancer, Lancet, 396, 635, 10.1016/S0140-6736(20)31288-5 Song, 2022, Ziyin Huatan Recipe, a Chinese herbal compound, inhibits migration and invasion of gastric cancer by upregulating RUNX3 expression, J Integr Med, 20, 355, 10.1016/j.joim.2022.02.006 Li, 2021, Traditional Chinese medicine for prevention and treatment of hepatocellular carcinoma: A focus on epithelial-mesenchymal transition, J Integr Med, 19, 469, 10.1016/j.joim.2021.08.004 Li, 2010, Study on the mechanism of xiaotan sanjie recipe for inhibiting proliferation of gastric cancer cells, J Tradit Chin Med, 30, 249, 10.1016/S0254-6272(10)60051-9 Pang, 2011, Effect of xiaotan sanjie recipe on expressions of VEGF-C and VEGFR-3 in nude mice with transplanted human gastric adenocarcinoma cell MKN-45, Zhongguo Zhong Xi Yi Jie He Za Zhi, 31, 204 Pinho, 2013, E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V, Biochim Biophys Acta, 1830, 2690, 10.1016/j.bbagen.2012.10.021 Minikes, 2023, E-cadherin is a biomarker for ferroptosis sensitivity in diffuse gastric cancer, Oncogene, 42, 848, 10.1038/s41388-023-02599-5 Pinho, 2009, The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin, Hum Mol Genet, 18, 2599, 10.1093/hmg/ddp194 Liu, 2022, IGF2BP2 promotes gastric cancer progression by regulating the IGF1R-RhoA-ROCK signaling pathway, Cell Signal, 94, 10.1016/j.cellsig.2022.110313 Bi, 2023, Retrospective analysis of risk factors for distant metastasis of early-onset gastric cancer during the perioperative period, Front Oncol, 13, 10.3389/fonc.2023.1003977 Namikawa, 2022, Frequency and therapeutic strategy for patients with ovarian metastasis from gastric cancer, Langenbecks Arch Surg, 407, 2301, 10.1007/s00423-022-02543-3 Wu, 2022, Survival benefit of primary tumor resection for gastric cancer with liver metastasis: a propensity score-matched, population-based study, Front Oncol, 12, 10.3389/fonc.2022.1039086 Kahroba, 2019, Exosomes: from carcinogenesis and metastasis to diagnosis and treatment of gastric cancer, CellMol Life Sci, 76, 1747 Tang, 2021, Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications, Mol Cancer, 20, 99, 10.1186/s12943-021-01396-6 Zhao, 2021, The significance of exosomal RNAs in the development, diagnosis, and treatment of gastric cancer, Genes, 12, 73, 10.3390/genes12010073 Pinho, 2015, Glycosylation in cancer: mechanisms and clinical implications, Nat Rev Cancer, 15, 540, 10.1038/nrc3982 de-Souza-Ferreira, 2023, Aberrant N-glycosylation in cancer: MGAT5 and beta1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression, CellOncol (Dordr), 46, 481 Lagana, 2006, Galectin binding to MGAT5-modified N-glycans regulates fibronectin matrix remodeling in tumor cells, Mol Cell Biol, 26, 3181, 10.1128/MCB.26.8.3181-3193.2006 Lin, 2022, Prediction of distant metastasis and survival prediction of gastric cancer patients with metastasis to the liver, lung, bone, and brain: research based on the SEER database, Ann Transl Med, 10, 16, 10.21037/atm-21-6295 Sirody, 2022, Patterns of gastric cancer metastasis in the United States, Am J Surg, 224, 445, 10.1016/j.amjsurg.2022.01.024 Polkowska-Pruszynska, 2017, Liver metastases from gastric carcinoma: a case report and review of the literature, Curr Probl Cancer, 41, 222, 10.1016/j.currproblcancer.2017.03.003 Hanaki, 2022, The significance of surgical intervention for metasynchronous liver metastasis in gastric cancer: a single-centre analysis, Anticancer Res, 42, 2177, 10.21873/anticanres.15700 Luo, 2019, Surgery strategies for gastric cancer with liver metastasis, Front Oncol, 9, 1353, 10.3389/fonc.2019.01353 Abe, 2020, Lung metastasis from gastric cancer presenting as diffuse ground-glass opacities, Respir Med Case Rep, 30 Wang, 2019, Melatonin inhibits lung metastasis of gastric cancer in vivo, Biomed Pharmacother, 117, 10.1016/j.biopha.2019.109018