Worms, bugs and drugs: Caenorhabditis elegans as a model for host-microbe-drug interactions
Tài liệu tham khảo
Wu, 2015, Linking microbiota to human diseases: a systems biology perspective, Trends Endocrinol Metab, 26, 758, 10.1016/j.tem.2015.09.011
Spanogiannopoulos, 2016, The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism, Nat Rev Microbiol, 14, 273, 10.1038/nrmicro.2016.17
Wallace, 2010, Alleviating cancer drug toxicity by inhibiting a bacterial enzyme, Science, 330, 831, 10.1126/science.1191175
Viaud, 2013, The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide, Science, 342, 971, 10.1126/science.1240537
Iida, 2013, Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment, Science, 342, 967, 10.1126/science.1240527
Vetizou, 2015, Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota, Science, 350, 1079, 10.1126/science.aad1329
Felix, 2010, The natural history of Caenorhabditis elegans, Curr Biol, 20, R965, 10.1016/j.cub.2010.09.050
Zhang, 2017, C. elegans and its bacterial diet as a model for systems-level understanding of host-microbiota interactions, Curr Opin Biotechnol, 46, 74, 10.1016/j.copbio.2017.01.008
MacNeil, 2013, Diet-induced developmental acceleration independent of TOR and insulin in C. elegans, Cell, 153, 240, 10.1016/j.cell.2013.02.049
Iatsenko, 2014, B. subtilis GS67 protects C. elegans from Gram-positive pathogens via fengycin-mediated microbial antagonism, Curr Biol, 24, 2720, 10.1016/j.cub.2014.09.055
Kamath, 2003, Systematic functional analysis of the Caenorhabditis elegans genome using RNAi, Nature, 421, 231, 10.1038/nature01278
Watson, 2013, Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response, Cell, 153, 253, 10.1016/j.cell.2013.02.050
Watson, 2014, Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits, Cell, 156, 759, 10.1016/j.cell.2014.01.047
Watson, 2016, Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans, Elife, 5, e17670, 10.7554/eLife.17670
Garcia-Gonzalez, 2017, Bacterial metabolism affects the C. elegans response to cancer chemotherapeutics, Cell, 169, 431, 10.1016/j.cell.2017.03.046
Scott, 2017, Host-microbe co-metabolism dictates cancer drug efficacy in C. elegans, Cell, 169, 442, 10.1016/j.cell.2017.03.040
Baba, 2006, Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection, Mol Syst Biol, 2, 10.1038/msb4100050
Longley, 2003, 5-fluorouracil: mechanisms of action and clinical strategies, Nat Rev Cancer, 3, 330, 10.1038/nrc1074
Ison, 2016, FDA approval: uridine triacetate for the treatment of patients following fluorouracil or capecitabine overdose or exhibiting early-onset severe toxicities following administration of these drugs, Clin Cancer Res, 22, 4545, 10.1158/1078-0432.CCR-16-0638
Cantor, 2017, Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase, Cell, 169, 258, 10.1016/j.cell.2017.03.023
