When pregnancy-associated hypertriglyceridemia goes above and beyond the risk of pancreatitis

Alessandro Baracchi1, Federica Piani1,2, Daniela Degli Esposti2, Davide Agnoletti1,2, Claudio Borghi1,2, Sergio D’Addato1,2
1Hypertension and Cardiovascular Risk Research Center, Medical and Surgical Sciences Dept., Alma Mater Studiorum University of Bologna, Bologna, Italy
2Cardiovascular Medicine Unit, Heart, Chest and Vascular Dept., IRCCS Azienda-Ospedaliero Universitaria Di Bologna, Bologna, Italy

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Ghio A, Bertolotto A, Resi V, Volpe L, Di Cianni G (2011) Triglyceride metabolism in pregnancy. Adv Clin Chem 55:133–153 Wong B, Ooi TC, Keely E (2015) Severe gestational hypertriglyceridemia: a practical approach for clinicians. Obstet Med 8(4):158–167 Basaran A (2009) Pregnancy-induced hyperlipoproteinemia: review of the literature. Reprod Sci 16(5):431–437 Kleess LE, Janicic N (2019) Severe hypertriglyceridemia in pregnancy: a case report and review of the literature. AACE Clin Case Rep 5(2):e99–e103 Simha V (2020) Management of hypertriglyceridemia. BMJ 371:m3109 Gupta M, Liti B, Barrett C, Thompson PD, Fernandez AB (2022) Prevention and management of hypertriglyceridemia-induced acute pancreatitis during pregnancy: a systematic review. Am J Med 135(6):709–714 Dash S, Tiwari M, Dash P, Kar K, Mohakud NK (2022) Complications of hypertriglyceridemia in pregnancy and its impact on neonates: a hospital-based study from Odisha. Cureus 14(8):e28399 Mauri M, Calmarza P, Ibarretxe D (2021) Dyslipemias and pregnancy, an update. Clin Investig Arterioscler 33(1):41–52 Goldberg AS, Hegele RA (2012) Severe hypertriglyceridemia in pregnancy. J Clin Endocrinol Metab 97(8):2589–2596 Nguyen NT, Nath PV, Mai VQ, Shakir MKM, Hoang TD (2021) Treatment of severe hypertriglyceridemia during pregnancy with high doses of omega-3 fatty acid and plasmapheresis. AACE Clin Case Rep 7(3):211–215 Saadi HF, Kurlander DJ, Erkins JM, Hoogwerf BJ (1999) Severe hypertriglyceridemia and acute pancreatitis during pregnancy: treatment with gemfibrozil. Endocr Pract 5(1):33–36 Al-Shali K, Wang J, Fellows F, Huff MW, Wolfe BM, Hegele RA (2002) Successful pregnancy outcome in a patient with severe chylomicronemia due to compound heterozygosity for mutant lipoprotein lipase. Clin Biochem 35(2):125–130 Wiznitzer A, Mayer A, Novack V, Sheiner E, Gilutz H, Malhotra A et al (2009) Association of lipid levels during gestation with preeclampsia and gestational diabetes mellitus: a population-based study. Am J Obstet Gynecol 201(5):482.e1–8 Cruciat G, Nemeti G, Goidescu I, Anitan S, Florian A (2020) Hypertriglyceridemia triggered acute pancreatitis in pregnancy - diagnostic approach, management and follow-up care. Lipids Health Dis 19(1):2 Ray JG, Diamond P, Singh G, Bell CM (2006) Brief overview of maternal triglycerides as a risk factor for pre-eclampsia. BJOG 113(4):379–386 Kampman MA, Bilardo CM, Mulder BJ, Aarnoudse JG, Ris-Stalpers C, van Veldhuisen DJ et al (2015) Maternal cardiac function, uteroplacental Doppler flow parameters and pregnancy outcome: a systematic review. Ultrasound Obstet Gynecol 46(1):21–28 Chassen SS, Zemski-Berry K, Raymond-Whish S, Driver C, Hobbins JC, Powell TL (2022) Altered Cord blood lipid concentrations correlate with birth weight and doppler velocimetry of fetal vessels in human fetal growth restriction pregnancies. Cells 11(19):3110 Bugatto F, Quintero-Prado R, Visiedo FM, Vilar-Sánchez JM, Figueroa-Quiñones A, López-Tinoco C et al (2018) The influence of lipid and proinflammatory status on maternal uterine blood flow in women with late onset gestational diabetes. Reprod Sci 25(6):837–843 Rinkūnienė E, Butkutė E, Puronaitė R, Petrulionienė Ž, Dženkevičiūtė V, Kasiulevičius V et al (2017) Arterial function parameters in patients with metabolic syndrome and severe hypertriglyceridemia. J Clin Lipidol 11(4):901–907 Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ et al (2014) Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol 63(7):636–646