What Does Synthetic Biology Have to Do with Biology?

Springer Science and Business Media LLC - Tập 4 - Trang 291-302 - 2009
Evelyn Fox Keller1
1Program in Science, Technology and Society, Building E51 Room 171, Massachusetts Institute of Technology, Cambridge, USA

Tóm tắt

This article examines the historical roots of synthetic biology, highlighting the multiple meanings and understandings of the term. Synthetic biology as it is used today refers to an especially wide range of endeavors, embodying an equally wide range of aims, and having correspondingly various relations to the activities generally included in the discipline of biology. To address the question of what synthetic biology has to do with biology, this article illustrates some of the ways in which the entanglement of synthetic biology as the epitome of technoscience and synthetic biology as an alternative, artificial biology plays out in three different examples of synthetic biology—one current and two historical.

Tài liệu tham khảo

Collingwood R.G. (1940). An essay on metaphysics. Oxford: Oxford UP. Edge (online magazine) (2008) Engineering biology: A talk with Drew Endy. URL (consulted July 2009): www.edge.org/3rd_culture/endy08/endy08_index.html Forman P. (2007). The primacy of science in modernity, of technology in postmodernity and of ideology in the history of technology. History and Technology, 23, 1–152. Forster A.C., & Church G.M. (2007). Synthetic biology projects in vitro. Genome Research, 17, 1 April, 1–6. Fox Keller E. (2002) Making sense of life: Explaining biological development with models, metaphors and machines. Cambridge, MA: Harvard University Press. Leduc S. (1910). Théorie physico-chimique de la vie et générations spontanées. Paris: A. Poinat. Leduc S. (1911). The mechanism of life, trans. W.D. Butcher . New York: Rebman Co., and London: Heinemann. Pauly P.J. (1987a). Controlling life: Jacques Loeb and the engineering ideal in biology. Oxford: Oxford University Press. Pauly P.J. (1987b). The invention of artificial parthenogenesis. In Controlling life: Jacques Loeb and the engineering ideal in biology, ch. 5. Available online, URL (consulted July 2009): 8e.devbio.com/article.php?id=72 Turing A.M. (1952). The chemical basis of morphogenesis, Philosophical Transactions of the Royal Society London, B237, 37–72. Vincent B.B. (2008). Technoscience and convergence: A transmutation of values?, Paper presented at Summer School on ‘Ethics of Converging Technologies’, 21–26 September, Alsfeld, Germany, URL (accessed July 2009): hal.archives-ouvertes.fr/docs/00/35/08/04/PDF/06BBV.pdf