Western diet associated with increased post-stroke depressive symptoms

Journal of Nutritional Science - Tập 11 - 2022
Laurel Cherian1, Puja Agarwal2, Thomas Holland3, Julie A. Schneider2, Neelum T. Aggarwal2,1
1Rush Department of Neurological Sciences, Rush University Medical Center, 1725 W Harrison St, Chicago, IL 60612, USA
2Rush Alzheimer's Disease Center, 1750 W Harrison St, Chicago, IL 60612, USA
3Rush Institute for Healthy Aging, 1653 W. Congress Parkway, Chicago, IL 606012, USA

Tóm tắt

Abstract The present study examines the association of diet with depressive symptoms among stroke survivors from a community cohort of older adults. Depression is common after stroke. A healthy diet has previously been associated with fewer depressive symptoms in older individuals, but it is unknown if this effect is also seen in stroke survivors. Eighty-six participants from the Memory and Aging Project with a history of stroke at their study baseline enrolment, complete dietary data and two or more assessments for depression were included in this observational prospective cohort analysis. Depressive symptoms were assessed annually with a 10-item version of the Center for Epidemiologic Studies Depression scale. Diet was assessed using a validated food-frequency questionnaire administered at baseline. Diet scores were based on analysis of participants’ reported intakes of 144 food items. A generalised estimating equation (GEE) model was applied to examine the association of diet score with depressive symptoms. The study participants had a mean age of 82 ± 7⋅17 years and 14⋅42 ± 2⋅61 years of education, and 82⋅56 % were female. Western diet score was positively associated with depressive symptoms over time (diet score tertile 3 v. tertile 1: β = 0⋅22, se = 0⋅09, P = 0⋅02; P for trend = 0⋅022). Interaction with sex suggested a stronger effect in females. A Western diet was associated with more post-stroke depressive symptoms, suggesting nutrition is important not only for reducing cerebrovascular risk, but for protecting post-stoke mental health as well.

Từ khóa


Tài liệu tham khảo

Cherian, 2019, Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet slows cognitive decline after stroke, J Prev Alzheimer's Dis, 6, 267

29. Cherian, L , Holland, T , Agarwal, P , . (2020) Diet pattern in acute stroke patients, a semiquantitative analysis. In American Academy of Neurology Annual Meeting, April 25th–May 1st, Toronto, Canada.

10.1136/jnnp.2007.134965

10.1177/089826439300500202

10.1159/000337552

10.4135/9781412984652

10.1097/YCO.0b013e328315a561

10.1016/S0304-3940(96)12460-5

10.1371/journal.pone.0024805

10.1093/gerona/glaa044

10.1590/1980-57642020dn14-010007

10.1016/j.jand.2012.07.007

10.1161/STROKEAHA.106.471805

10.3233/JAD-179939

10.1097/MD.0000000000005349

10.1016/j.ypmed.2006.12.009

10.2174/0929867321666141106122319

10.1038/ejcn.2010.86

10.1093/aje/kwg290

10.1016/j.jalz.2015.04.011

10.1002/mus.20702

10.1093/ajcn/69.2.243

10.1176/appi.ajp.2009.09060881

10.1001/archinte.159.15.1701

10.1016/j.jada.2009.11.025

10.3945/ajcn.113.069880

10.1177/2167702616645777

10.3109/00048670903571598

10.1161/01.STR.0000219643.43966.0d

10.1192/bjp.bp.108.058925

10.1111/ijs.12190

10.1111/ijs.12357

10.1111/j.1747-4949.2010.00565.x

10.2174/156720512801322663

10.1016/j.jpsychores.2009.11.006

Thông tin
Thông tin xuất bản

Journal of Nutritional Science

Tập 11

Thông tin tác giả