Weight loss after head and neck cancer: A dynamic relationship with depressive symptoms

Head and Neck - Tập 39 Số 2 - Trang 370-379 - 2017
Julia R. Liew1, Rebecca L. Brock2, Alan J. Christensen3,1, Lucy Hynds Karnell4, Nitin A. Pagedar4, Gerry F. Funk5
1Department of Psychology, The University of Iowa, Iowa City, Iowa
2Department of Psychology The University of Nebraska – Lincoln Lincoln Nebraska
3Department of Internal Medicine, The University of Iowa College of Medicine, Iowa City, Iowa
4Department of Otolaryngology – Head and Neck Surgery The University of Iowa College of Medicine Iowa City Iowa
5Department of Otolaryngology, Grande Ronde Hospitals and Clinics, La Grande, Oregon

Tóm tắt

ABSTRACTBackgroundWeight loss and depressive symptoms are critical head and neck cancer outcomes, yet their relation over the illness course is unclear.MethodsAssociations between self‐reported depressive symptoms and objective weight loss across the year after head and neck cancer diagnosis were examined using growth curve modeling techniques (n = 564).ResultsA reciprocal covariation pattern emerged–changes in depressive symptoms over time were associated with same‐month changes in weight loss (t [1148] = 2.05; p = .041), and changes in weight loss were associated with same‐month changes in depressive symptoms (t [556] = 2.43; p = .015). To the extent that depressive symptoms increased, patients lost incrementally more weight than was lost due to the passage of time and vice versa. Results also suggested that pain and eating‐related quality of life might explain the reciprocal association between depressive symptoms and weight loss.ConclusionIn head and neck cancer, a transactional interplay between depressive symptoms and weight loss unfolds over time. © 2016 Wiley Periodicals, Inc. Head Neck 39: 370–379, 2017

Từ khóa


Tài liệu tham khảo

10.1007/s00520-009-0684-5

10.1002/(SICI)1097-0347(199809)20:6<540::AID-HED9>3.0.CO;2-J

10.1002/(SICI)1097-0347(199708)19:5<419::AID-HED9>3.0.CO;2-2

10.1007/s00520-014-2180-9

10.1002/hed.21174

10.1016/S0167-8140(03)00040-9

10.1016/j.nut.2009.06.012

10.1016/S0936-6555(03)00155-9

10.1002/(SICI)1097-0142(19990801)86:3<519::AID-CNCR22>3.0.CO;2-S

10.1002/hed.23983

10.1002/hed.23599

10.1016/j.clnu.2005.12.007

10.1007/s00520-013-1870-z

10.1097/00002820-200511000-00004

10.1067/mhn.2001.120428

10.1007/s00520-011-1087-y

10.1093/jnci/85.12.979

10.1002/lary.23877

10.1016/j.oraloncology.2014.06.009

10.1002/cncr.25041

10.1002/hed.20172

10.1037/a0029940

10.1002/pon.734

10.1093/jncimonographs/lgh014

10.1002/1099-1611(200101/02)10:1<19::AID-PON501>3.0.CO;2-6

10.1016/j.ijrobp.2008.04.010

10.1016/j.otohns.2006.06.1278

10.1038/sj.bjc.6690420

10.1002/1097-0347(200012)22:8<799::AID-HED9>3.0.CO;2-E

10.1002/(SICI)1097-0347(199907)21:4<291::AID-HED1>3.0.CO;2-B

10.1002/hed.20370

10.1176/appi.psy.48.2.142

10.1007/s00520-011-1282-x

10.1007/s00520-004-0635-0

10.1007/s00520-011-1224-7

10.1159/000089669

10.1016/S0272-6386(03)00201-4

10.3109/00365529709011218

10.1016/j.jamda.2007.07.008

10.1111/j.0737-1209.2005.220207.x

10.1016/j.clnu.2010.01.006

10.1016/j.clnu.2013.05.007

Friend R, 1997, Serum albumin and depression in end‐stage renal disease, Adv Perit Dial, 13, 155

10.1017/S0007114509990900

10.1001/archotol.1988.01860240099032

10.1016/j.archger.2013.12.007

10.1002/hed.20221

10.1007/s00520-003-0568-z

Cederholm T, 2003, Psychological effects of generalized nutritional deprivation in the elderly, Adv Food Nutr Res, 47, 143

10.1007/s00520-014-2312-2

10.1001/archoto.2009.107

10.1634/theoncologist.2012-0299

Beck AT, 1979, Cognitive therapy of depression (Guilford Clinical Psychology and Psychopathology)

10.1016/0272-7358(88)90050-5

10.1002/hed.10245

10.15288/jsa.1975.36.117

10.15288/jsa.1979.40.845

Raudenbush SW, 2002, Hierarchical linear models: applications and data analysis methods

Raudenbush SW, 2004, Hierarchical linear and nonlinear modeling

10.1146/annurev.psych.52.1.501

Thông tin
Thông tin xuất bản

Head and Neck

Tập 39 Số 2

370-379

Thông tin tác giả