WITHDRAWN: Investigating the link of ceramide synthases (CerSes) 4 and 5 in endometrial and colon cancers

Rahaba Mojakgomo1, Zukile Mbita2, Zodwa Dlamini1
1College of Agriculture and Environmental Sciences, University of South Africa, Private Bag X6, Florida, 1709 Johannesburg, South Africa
2Department of Biochemistry, Microbiology and Biotechnology, University of Limpopo, Private Bag X1106, Sovenga 0727, South Africa

Tài liệu tham khảo

Burstein, 2010, American Society of clinical oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer, J. Clin. Oncol., 28, 3784, 10.1200/JCO.2009.26.3756 Hanahan, 2011, Hallmarks of cancer: the next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013 Hanun, 2008, Principles of bioactive lipid signalling: lessons from sphingolipids, Nat. Rev. Mol. Cell Biol., 9, 139, 10.1038/nrm2329 Hartmann, 2012, Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth, Int. J. Biochem. Biol., 44, 620, 10.1016/j.biocel.2011.12.019 Henry, 2013, Targeting the ceramide system in cancer, Cancer Lett., 332, 286, 10.1016/j.canlet.2011.07.010 Huang, 2011, Apoptotic sphingolipid ceramide in cancer therapy, J. Lipids, 2011, 1, 10.1155/2011/565316 Karahatay, 2007, Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C (18)-ceramide in HNSCC tumours correlates with lymphovascular invasion and nodal metastasis, Cancer Lett., 256, 101, 10.1016/j.canlet.2007.06.003 Knapp, 2010, Altered sphingolipid metabolism in human endometrial cancer, Prostaglandins Other Lipid Mediat., 92, 62, 10.1016/j.prostaglandins.2010.03.002 Knapp, 2010, Altered sphingolipid metabolism in human endometrial cancer, Prostaglandins Other Lipid Mediat., 92, 62, 10.1016/j.prostaglandins.2010.03.002 Levy, 2010, Lipids: mammalian ceramide synthases, IUBMB Life, 62, 347 Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method, Methods, 25, 402, 10.1006/meth.2001.1262 Lu, 2011, Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi, Hepatobiliary Pancreat. Dis. Int., 10, 303, 10.1016/S1499-3872(11)60050-7 Matsumoto, 2008, Estrogen signaling ability in human endometrial cancer through the cancer–stromal interaction, Endocr. Relat. Cancer, 15, 451, 10.1677/ERC-07-0227 Meyers-Needham, 2011, Concerted functions of HDAC1 and microRNA-574-5p repress alternatively spliced ceramide synthase 1 expression in human cancer cells, Mol. Med., 4, 78 Mizutani, 2005, Mammalian Lass6 and its related family members regulate synthesis of specific ceramides, Biochem. J., 390, 263, 10.1042/BJ20050291 Ogretmen, 2006, Sphingolipids in cancer: regulation of pathogenesis and therapy, Fed. Am. Soc. Exp. Biol. Lett., 580, 5467, 10.1016/j.febslet.2006.08.052 Parkin, 2005, Global cancer statistics, 2002, Cancer J. Clin., 55, 74, 10.3322/canjclin.55.2.74 Parkin, 2008, Part I: cancer in Indigenous Africans—burden, distribution, and trends, Lancet Oncol., 9, 683, 10.1016/S1470-2045(08)70175-X Pewzner-Jung, 2006, When do Lasses (Longevity Assurance Genes) become CerS (ceramide synthases)?, J. Biol. Chem., 281, 25001, 10.1074/jbc.R600010200 Rost, 1999, Twilight zone of protein sequence alignments, Protein Eng., 12, 85, 10.1093/protein/12.2.85 Schiffman, 2009, Ceramide synthases and ceramide levels are increased in breast cancer tissue, Carcinogenesis, 30, 745, 10.1093/carcin/bgp061 Schmittgen, 2008, Analyzing real-time PCR data by the comparative CT method, Nat. Protoc., 3, 1101, 10.1038/nprot.2008.73 Senkal, 2007, Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas, Mol. Cancer Ther., 6, 712, 10.1158/1535-7163.MCT-06-0558 Senkal, 2010, Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways, Fed. Am. Soc. Exp. Biol. J., 24, 296 Teufel, 2009, The longevity assurance homologue of yeast lag1 (Lass) gene family (review), Int. J. Mol. Med., 23, 135 Wu, 2004, Identification of one exon deletion of intestinal alkaline sphingimyelase in colon cancer HT-29 cells and a differentiation-related expression of the wild-type enzyme in Caco-2 cells, Carcinogenesis, 25, 1327, 10.1093/carcin/bgh140