Vitamin E, diabetes and related diseases: an update

Evans HM, Bishop KS (1922) On the existence of a hitherto unrecognized dietary factor essential for reproduction. Science 56:650–651 Emerson OH, Emerson GA, Evans HM (1936) The isolation from cottonseed oil of an alcohol resembling alpha tocopherol from wheat germ oil. Science 83:421 Emerson OH, Emerson GA, Evans HM (1939) The occurrence of gamma tocopherol in corn embryo oil. Science 89:183 Whittle KJ, Dunphy PJ, Pennock JF (1966) The isolation and properties of delta-tocotrienol from Hevea latex. Biochem J 100:138–145 Pennock JF, Hemming FW, Kerr JD (1964) A reassessment of tocopherol in chemistry. Biochem Biophys Res Commun 17:542–548 Herrera E, Barbas C (2001) Vitamin E: action, metabolism and perspectives. J Physiol Biochem 57:43–56 Packer L, Weber SU, Rimbach G (2001) Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling. J Nutr 131:369S–373S Bauernfeind JB (1980) Tocopherols in food. Vitamin E. Comprehensive treatise. Marcel Dekker, New York, pp 99–167 Burton GW, Traber MG (1990) Vitamin E: antioxidant activity, biokinetics, and bioavailability. Annu Rev Nutr 10:357–382 Birringer M, EyTina JH, Salvatore BA, Neuzil J (2003) Vitamin E analogues as inducers of apoptosis: structure and function relation. Br J Cancer 88:1948–1955 Cerecetto H, López GV (2007) Antioxidants derived from vitamin E: an overview. Mini Rev Med Chem 7:315–338 Bartlett HE, Eperjesi F (2008) Nutritional supplementation for type 2 diabetes: a systematic review. Ophthalmic Physiol Opt 28:503–523 Catignani GL, Bieri JG (1977) Rat liver alpha-tocopherol binding protein. Biochim Biophys Acta 497:349–357 Hosomi A, Arita M, Sato Y, Kiyose C, Ueda T, Igarashi O, Arai H, Inoue K (1997) Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett 409:105–108 Kostner GM, Oettl K, Jauhiainen M, Ehnholm C, Esterbauer H, Dieplinger H (1995) Human plasma phospholipid transfer protein accelerates exchange/transfer of alpha-tocopherol between lipoproteins and cells. Biochem J 305:659–667 Goti D, Reicher H, Malle E, Kostner GM, Panzenboeck U, Sattler W (1998) High-density lipoprotein (HDL3)-associated alpha-tocopherol is taken up by HepG2 cells via the selective uptake pathway and resecreted with endogenously synthesized apo-lipoprotein B-rich lipoprotein particles. Biochem J 332:57–65 Fechner H, Schlame M, Guthmann F, Stevens PA, Rustow B (1998) Alpha- and delta-tocopherol induce expression of hepatic alpha-tocopherol-transfer-protein mRNA. Biochem J 331:577–581 Yokota T, Shiojiri T, Gotoda T, Arita M, Arai H, Ohga T, Kanda T, Suzuki J, Imai T, Matsumoto H, Harino S, Kiyosawa M, Mizusawa H, Inoue K (1997) Friedreich-like ataxia with retinitis pigmentosa caused by the His101Gln mutation of the alpha-tocopherol transfer protein gene. Ann Neurol 41:826–832 Roxborough HE, Burton GW, Kelly FJ (2000) Inter- and intra-individual variation in plasma and red blood cell vitamin E after supplementation. Free Radic Res 33:437–445 Brigelius-Flohe R, Kelly FJ, Salonen JT, Neuzil J, Zingg JM, Azzi A (2002) The European perspective on vitamin E: current knowledge and future research. Am J Clin Nutr 76:703–716 Drevon CA (1991) Absorption, transport and metabolism of vitamin E. Free Radic Res Commun 14:229–246 Copp RP, Wisniewski T, Hentati F, Larnaout A, Ben Hamida M, Kayden HJ (1999) Localization of alphatocopherol transfer protein in the brains of patients with ataxia with vitamin E deficiency and other oxidative stress related neurodegenerative disorders. Brain Res 822:80–87 Tamaru Y, Hirano M, Kusaka H, Ito H, Imai T, Ueno S (1997) Alpha-tocopherol transfer protein gene: exon skipping of all transcripts causes ataxia. Neurology 49:584–588 Debier C (2007) Vitamin E during pre- and postnatal periods. Vitam Horm 76:357–373 Kempnà P, Zingg JM, Ricciarelli R, Hierl M, Saxena S, Azzi A (2003) Cloning of novel human SEC14p like proteins: cellular localization, ligand binding and functional properties. Free Radic Biol Med 34:1458–1472 Brigelius-Flohé R (2006) Bioactivity of vitamin E. Nutr Res Rev 19:174–186 Wang X, Quinn PJ (2000) The location and function of vitamin E in membranes (review). Mol Membr Biol 17:143–156 Fukuzawa K (2008) Dynamics of lipid peroxidation and antioxidation of alpha-tocopherol in membranes. J Nutr Sci Vitaminol 54:273–285 Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ (2003) Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 361:2017–2023 Munteanu A, Zingg JM, Azzi A (2004) Anti-atherosclerotic effects of vitamin E—myth or reality? J Cell Mol Med 8:59–76 World Health Organization (2006) WHO definition and diagnosis of diabetes mellitus and intermediate hyperglycemia. Cambridge University Press, Cambridge Watkins P, Amiel S, Howell S, Turner E (2003) Epidemiology of diabetes. In: Watkins P, Amiel S, Howell S, Turner E (eds) Diabetes and its management. Blackwell Publishing, Oxford, pp 16–22 Honarbakhsh S, Schachter M (2009) Vitamins and cardiovascular disease. Br J Nutr 101:1113–1131 Giugliano D, Ceriello A, Paolisso G (1996) Oxidative stress and diabetic vascular complications. Diabetes Care 19:257–265 Liu S, Lee IM, Song Y, Van Denburgh M, Cook NR, Manson JE, Buring JE (2006) Vitamin E and risk of type 2 diabetes in the women’s health study randomized controlled trial. Diabetes 55:2856–2862 Lee IM, Cook NR, Gaziano JM, Gordon D, Ridker PM, Manson JE, Hennekens CH, Buring JE (2005) Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women’s Health Study: a randomized controlled trial. JAMA 294:56–65 Ward NC, Wu JH, Clarke MW, Puddey IB, Burke V, Croft KD, Hodgson JM (2007) The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. J Hypertens 25:227–234 Wu JHY, Ward NC, Indrawan AP, Almeida CA, Hodgson JM, Proudfoot JM, Puddey IB, Croft KD (2007) Effects of alpha-tocopherol and mixed tocopherol supplementation on markers of oxidative stress and inflammation in type 2 diabetes. Clin Chem 53:511–519 McSorley PT, Bell PM, Young IS, Atkinson AB, Sheridan B, Fee JP, McCance DR (2005) Endothelial function, insulin action and cardiovascular risk factors in young healthy adult offspring of parents with type 2 diabetes: effect of vitamin E in a randomized double-blind, controlled clinical trial. Diabet Med 22:703–710 Boshtam M, Rafiei M, Golshadi ID, Ani M, Shirani Z, Rostamshirazi M (2005) Long-term effects of oral vitamin E supplement in type II diabetic patients. Int J Vitam Nutr Res 75:341–346 Ble-Castillo J, Carmona-Diaz E, Mendez J, Larios-Medina F, Mediina-Santillam R, Cleva-Villanueva G, Diaz-Zagoya J (2005) Effect of α-tocopherol on the metabolic control and oxidative stress in female type 2 diabetics. Biomed Pharmacother 59:290–295 Clarke MW, Ward NC, Wu JH, Hodgson JM, Puddey IB, Croft KD (2006) Supplementation with mixed tocopherols increases serum and blood cell gammatocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetes. Am J Clin Nutr 83:95–102 Ulker S, McMaster D, McKeown PP, Bayraktutan U (2004) Antioxidant vitamins C and E ameliorate hyperglycemia-induced oxidative stress in coronary endothelial cells. Diabetes Obes Metab 6:442–451 Cinar MG, Ulker S, Alper G, Evinc A (2001) Effect of dietary vitamin E supplementation on vascular reactivity of the thoracic aorta in streptozotocin-diabetic rats. Pharmacology 62:56–64 Gocmen C, Secilmis A, Kumcu EK, Ertug PU, Onder S, Dikmen A, Baysal F (2000) Effects of vitamin E and sodium selenate on neurogenic and endothelial relaxation of corpus cavernosum in the diabetic mouse. Eur J Pharmacol 398:93–98 Keegan A, Walbank H, Cotter MA, Cameron NE (1995) Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta. Diabetologia 38:1475–1478 Kunisaki M, Bursell SE, Clermont AC, Ishii H, Ballas LM, Jirousek MR, Umeda F, Nawata H, King GL (1995) Vitamin E prevents diabetes-induced abnormal retinal blood flow via the diacylglycerol-protein kinase C pathway. Am J Physiol 269:E239–E246 Karasu C, Ozansoy G, Bozkurt O, Erdogan D, Omeroglu S (1997) Antioxidant and triglyceride-lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin diabetic rats. Antioxidants in Diabetes-Induced Complications (ADIC) Study. Metabolism 46:872–879 Karasu C, Ozansoy G, Bozkurt O, Erdogan D, Omeroglu S (1997) Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: reversal effects of dietary vitamin E. Gen Pharmacol 29:561–567 Dhein S, Kabat A, Olbrich A, Rösen P, Schröder H, Mohr FW (2003) Effect of chronic treatment with vitamin E on endothelial dysfunction in a type I in vivo diabetes mellitus model and in vitro. J Pharmacol Exp Ther 305:114–122 Gutierrez AD, de Serna DG, Robinson I, Schade DS (2009) The response of gamma vitamin E to varying dosages of alpha vitamin E plus vitamin C. Metabolism 58:469–478 Chui MH, Greenwood CE (2008) Antioxidant vitamins reduce acute meal-induced memory deficits in adults with type 2 diabetes. Nutr Res 28:423–429 Rizzo MR, Abbatecola AM, Barbieri M, Vietri MT, Cioffi M, Grella R, Molinari A, Forsey R, Powell J, Paolisso G (2008) Evidence for anti-inflammatory effects of combined administration of vitamin E and C in older persons with impaired fasting glucose: impact on insulin action. J Am Coll Nutr 27:505–511 Clarke MW, Burnett JR, Croft KD (2008) Vitamin E in human health and disease. Crit Rev Clin Lab Sci 45:417–450 The Heart Outcomes Prevention Evaluation (HOPE) Study Investigators (2000) Vitamin E supplementation, cardiovascular events in high risk patients. N Engl J Med 342:154–160 GISSI-Prevenzione Investigators (1999) Dietary supplementation with n-3 polyunsaturated fatty acids, vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 354:447–455 Stephens NG, Parsons A, Schofeld PM, Kelly F, Cheeseman K, Mitchinson MJ (1996) Randomized controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347:781–786 Frank M, Lache O, Enav B, Szafranek T, Levy NS, Ricklis RM, Levy AP (2001) Structure/function analysis of the anti-oxidant properties of haptoglobin. Blood 98:3693–3698 Asleh R, Guetta J, Kalet-Litman S, Miller-Lotan R, Levy AP (2005) Haptoglobin genotype and diabetes dependent differences in iron mediated oxidative stress in vitro and in vivo. Circ Res 96:435–441 Levy AP, Purosothaman KR, Levy NS, Purosothaman M, Strauss M, Asleh R, Marsh S, Cohen O, Moestrup SK, Moller HJ, Zias EA, Benhayon D, Fuster V, Moreno PR (2007) Downregulation of the hemoglobin scavenger receptor in individuals with diabetes and the Hp 2–2 genotype: implications for the response to intraplaque hemorrhage and plaque vulnerability. Circ Res 101:106–110 Milman U, Blum S, Shapira C, Aronson D, Miller-Lotan R, Anbinder Y, Alshiek J, Bennett L, Kostenko M, Landau M, Keidar S, Levy Y, Khemlin A, Radan A, Levy AP (2008) Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2–2 genotype: a prospective double-blinded clinical trial. Arterioscler Thromb Vasc Biol 28:341–347 Vignini A, Nanetti L, Moroni C, Testa R, Sirolla C, Marra M, Manfrini S, Fumelli D, Marcheselli F, Mazzanti L, Rabini RA (2008) A study on the action of vitamin E supplementation on plasminogen activator inhibitor type 1 and platelet nitric oxide production in type 2 diabetic patients. Nutr Metab Cardiovasc Dis 18:15–22 Bell SJ, Grochoski GT (2008) How safe is vitamin E supplementation? Crit Rev Food Sci Nutr 48:760–774