Vitamin E-based nanomedicines for anti-cancer drug delivery

Journal of Controlled Release - Tập 182 - Trang 33-44 - 2014
Nicolas Duhem1, Fabienne Danhier1, Véronique Préat1
1Université Catholique de Louvain, Louvain Drug Research Institute, Pharmaceutics and Drug Delivery, Avenue E. Mounier 73, B1.73.12., 1200 Brussels, Belgium.

Tóm tắt

Từ khóa


Tài liệu tham khảo

Plapied, 2011, Fate of polymeric nanocarriers for oral drug delivery, Curr. Opin. Colloid Interface Sci., 16, 228, 10.1016/j.cocis.2010.12.005

Farokhzad, 2009, Impact of nanotechnology on drug delivery, ACS Nano, 3, 16, 10.1021/nn900002m

Youan, 2008, Impact of nanoscience and nanotechnology on controlled drug delivery, Nanomedicine, 3, 401, 10.2217/17435889.3.4.401

Singh, 2009, Nanoparticle-based targeted drug delivery, Exp. Mol. Pathol., 86, 215, 10.1016/j.yexmp.2008.12.004

Hall, 2007, Characterization of nanoparticles for therapeutics, Nanomedicine, 2, 789, 10.2217/17435889.2.6.789

Kumari, 2010, Biodegradable polymeric nanoparticles based drug delivery systems, Colloids Surf. B Biointerfaces, 75, 1, 10.1016/j.colsurfb.2009.09.001

Steichen, 2012, A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics, Eur. J. Pharm. Sci., 48, 416, 10.1016/j.ejps.2012.12.006

Danhier, 2010, To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery, J. Control. Release, 148, 135, 10.1016/j.jconrel.2010.08.027

Bamrungsap, 2012, Nanotechnology in therapeutics: a focus on nanoparticles as a drug delivery system, Nanomedicine, 7, 1253, 10.2217/nnm.12.87

Bharali, 2009, Nanoparticles and cancer therapy: a concise review with emphasis on dendrimers, Int. J. Nanomedicine, 4, 1

Puri, 2009, Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic, Crit. Rev. Ther. Drug Carrier Syst., 26, 523, 10.1615/CritRevTherDrugCarrierSyst.v26.i6.10

Zhang, 2012, Vitamin E TPGS as a molecular biomaterial for drug delivery, Biomaterials, 33, 4889, 10.1016/j.biomaterials.2012.03.046

Vaidya, 2011, Bioconjugation of polymers: a novel platform for targeted drug delivery, Curr. Pharm. Des., 17, 1108, 10.2174/138161211795656873

Vijayakumar, 2013, Copolymers of poly(lactic acid) and d-alpha-tocopheryl polyethylene glycol 1000 succinate-based nanomedicines: versatile multifunctional platforms for cancer diagnosis and therapy, Expert Opin. Drug Deliv., 10, 529, 10.1517/17425247.2013.758632

Petros, 2010, Strategies in the design of nanoparticles for therapeutic applications, Nat. Rev. Drug Discov., 9, 615, 10.1038/nrd2591

Davis, 2008, Nanoparticle therapeutics: an emerging treatment modality for cancer, Nat. Rev. Drug Discov., 7, 771, 10.1038/nrd2614

Jain, 2010, Delivering nanomedicine to solid tumors, Nat. Rev. Clin. Oncol., 7, 653, 10.1038/nrclinonc.2010.139

Torchilin, 2010, Passive and active drug targeting: drug delivery to tumors as an example, Handb. Exp. Pharmacol., 3, 10.1007/978-3-642-00477-3_1

Mustacich, 2007, Vitamin E, Vitam. Horm., 76, 1, 10.1016/S0083-6729(07)76001-6

Wong, 2012, Tocotrienol research: past into present, Nutr. Rev., 70, 483, 10.1111/j.1753-4887.2012.00512.x

Guo, 2013, The applications of Vitamin E TPGS in drug delivery, Eur. J. Pharm. Sci., 49, 175, 10.1016/j.ejps.2013.02.006

Constantinides, 2006, Advances in the use of tocols as drug delivery vehicles, Pharm. Res., 23, 243, 10.1007/s11095-005-9262-9

Kline, 2007, Vitamin E and cancer, Vitam. Horm., 76, 435, 10.1016/S0083-6729(07)76017-X

Combs, 2012, Vitamin E, 181

Zingg, 2007, Vitamin E: an overview of major research directions, Mol. Aspects Med., 28, 400, 10.1016/j.mam.2007.05.004

Atkinson, 2010, The location and behavior of alpha-tocopherol in membranes, Mol. Nutr. Food Res., 54, 641, 10.1002/mnfr.200900439

Brigelius-Flohe, 2006, Bioactivity of vitamin E, Nutr. Res. Rev., 19, 174, 10.1017/S0954422407202938

Frank, 2005, Beyond vitamin E supplementation: an alternative strategy to improve vitamin E status, J. Plant Physiol., 162, 834, 10.1016/j.jplph.2005.04.017

Azzi, 2002, Non-antioxidant molecular functions of alpha-tocopherol (vitamin E), FEBS Lett., 519, 8, 10.1016/S0014-5793(02)02706-0

Brigelius-Flohe, 2002, The European perspective on vitamin E: current knowledge and future research, Am. J. Clin. Nutr., 76, 703, 10.1093/ajcn/76.4.703

Brigelius-Flohe, 2009, Vitamin E: the shrew waiting to be tamed, Free Radic. Biol. Med., 46, 543, 10.1016/j.freeradbiomed.2008.12.007

Prasad, 2003, Alpha-tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review, J. Am. Coll. Nutr., 22, 108, 10.1080/07315724.2003.10719283

Kline, 2004, Vitamin E and breast cancer, J. Nutr., 134, 3458S, 10.1093/jn/134.12.3458S

Constantinou, 2008, Vitamin E and cancer: an insight into the anticancer activities of vitamin E isomers and analogs, Int. J. Cancer, 123, 739, 10.1002/ijc.23689

Dong, 2009, Anticancer mechanisms of vitamin e succinate, Chin. J. Cancer, 28, 1, 10.5732/cjc.008.10182

Zingg, 2007, Modulation of signal transduction by vitamin E, Mol. Aspects Med., 28, 481, 10.1016/j.mam.2006.12.009

Dong, 2011, Mitochondrial targeting of alpha-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy, Free Radic. Biol. Med., 50, 1546, 10.1016/j.freeradbiomed.2011.02.032

Anbharasi, 2010, Doxorubicin conjugated to d-alpha-tocopheryl polyethylene glycol succinate and folic acid as a prodrug for targeted chemotherapy, J. Biomed. Mater. Res. A, 94, 730, 10.1002/jbm.a.32734

Wang, 2006, Vitamin E analogues as anticancer agents: lessons from studies with alpha-tocopheryl succinate, Mol. Nutr. Food Res., 50, 675, 10.1002/mnfr.200500267

Genentech website

Malafa, 2000, Vitamin E succinate promotes breast cancer tumor dormancy, J. Surg. Res., 93, 163, 10.1006/jsre.2000.5948

Malafa, 2002, Vitamin E inhibits melanoma growth in mice, Surgery, 131, 85, 10.1067/msy.2002.119191

Barnett, 2002, Vitamin E succinate inhibits colon cancer liver metastases, J. Surg. Res., 106, 292, 10.1006/jsre.2002.6466

Malafa, 2002, Inhibition of angiogenesis and promotion of melanoma dormancy by vitamin E succinate, Ann. Surg. Oncol., 9, 1023, 10.1007/BF02574523

Neuzil, 2001, Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements, FASEB J., 15, 403, 10.1096/fj.00-0251com

Stapelberg, 2005, Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress, J. Biol. Chem., 280, 25369, 10.1074/jbc.M414498200

Wu, 2001, Inhibitory effects of RRR-alpha-tocopheryl succinate on benzo(a)pyrene (B(a)P)-induced forestomach carcinogenesis in female mice, World J. Gastroenterol., 7, 60, 10.3748/wjg.v7.i1.60

Ramanathapuram, 2006, Vesiculated alpha-tocopheryl succinate enhances the anti-tumor effect of dendritic cell vaccines, Cancer Immunol. Immunother., 55, 166, 10.1007/s00262-005-0016-7

Collnot, 2006, Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers, J. Control. Release, 111, 35, 10.1016/j.jconrel.2005.11.005

Bansal, 2009, Novel formulation approaches for optimising delivery of anticancer drugs based on P-glycoprotein modulation, Drug Discov. Today, 14, 1067, 10.1016/j.drudis.2009.07.010

Collnot, 2007, Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity, Mol. Pharm., 4, 465, 10.1021/mp060121r

Youk, 2005, Enhanced anticancer efficacy of alpha-tocopheryl succinate by conjugation with polyethylene glycol, J. Control. Release, 107, 43, 10.1016/j.jconrel.2005.05.014

Yi, 2005, A polymeric nanoparticle consisting of mPEG-PLA-Toco and PLMA-COONa as a drug carrier: improvements in cellular uptake and biodistribution, Pharm. Res., 22, 200, 10.1007/s11095-004-1187-1

Noh, 2011, Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery, Biomaterials, 32, 849, 10.1016/j.biomaterials.2010.09.027

Liang, 2012, Alpha-tocopherol succinate-modified chitosan as a micellar delivery system for paclitaxel: preparation, characterization and in vitro/in vivo evaluations, Int. J. Pharm., 423, 480, 10.1016/j.ijpharm.2011.12.004

Tao, 2013, Nano-formulation of paclitaxel by vitamin E succinate functionalized pluronic micelles for enhanced encapsulation, stability and cytotoxicity, Colloids Surf. B Biointerfaces, 102, 604, 10.1016/j.colsurfb.2012.08.062

Saxena, 2012, Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer, Int. J. Nanomedicine, 7, 713

Zhao, 2011, Formulation and in vitro evaluation of quercetin loaded polymeric micelles composed of pluronic P123 and d-α-tocopheryl polyethylene glycol succinate, J. Biomed. Nanotechnol., 7, 358, 10.1166/jbn.2011.1298

Gao, 2008, Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin, Colloids Surf. B Biointerfaces, 64, 194, 10.1016/j.colsurfb.2008.01.021

Gill, 2012, Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines, Eur. J. Pharm. Sci., 46, 64, 10.1016/j.ejps.2012.02.010

Wang, 2012, Star-shape copolymer of lysine-linked di-tocopherol polyethylene glycol 2000 succinate for doxorubicin delivery with reversal of multidrug resistance, Biomaterials, 33, 6877, 10.1016/j.biomaterials.2012.06.019

Mi, 2011, Formulation of docetaxel by folic acid-conjugated d-alpha-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS(2K)) micelles for targeted and synergistic chemotherapy, Biomaterials, 32, 4058, 10.1016/j.biomaterials.2011.02.022

Muthu, 2012, Theranostic liposomes of TPGS coating for targeted co-delivery of docetaxel and quantum dots, Biomaterials, 33, 3494, 10.1016/j.biomaterials.2012.01.036

Muthu, 2011, Vitamin E TPGS coated liposomes enhanced cellular uptake and cytotoxicity of docetaxel in brain cancer cells, Int. J. Pharm., 421, 332, 10.1016/j.ijpharm.2011.09.045

Wang, 2012, Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin, Int. J. Nanomedicine, 7, 2325

Yu, 2012, Mitochondrial targeting topotecan-loaded liposomes for treating drug-resistant breast cancer and inhibiting invasive metastases of melanoma, Biomaterials, 33, 1808, 10.1016/j.biomaterials.2011.10.085

Raju, 2013, Trastuzumab-conjugated vitamin E TPGS liposomes for sustained and targeted delivery of docetaxel, Expert Opin. Drug Deliv., 6, 747, 10.1517/17425247.2013.777425

Shen, 2012, Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer, Biomaterials, 33, 8613, 10.1016/j.biomaterials.2012.08.007

Shen, 2013, Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles, Biomaterials, 34, 1581, 10.1016/j.biomaterials.2012.10.057

Liu, 2010, Paclitaxel nanocrystals for overcoming multidrug resistance in cancer, Mol. Pharm., 7, 863, 10.1021/mp100012s

Shieh, 2011, Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells, J. Control. Release, 152, 418, 10.1016/j.jconrel.2011.03.017

Song, 2011, Preparation and in vitro properties of redox-responsive polymeric nanoparticles for paclitaxel delivery, Colloids Surf. B Biointerfaces, 87, 454, 10.1016/j.colsurfb.2011.06.009

Zhang, 2007, Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery, Biomaterials, 28, 1889, 10.1016/j.biomaterials.2006.12.018

Sun, 2009, Trastuzumab-functionalized nanoparticles of biodegradable copolymers for targeted delivery of docetaxel, Nanomedicine, 4, 431, 10.2217/nnm.09.17

Cao, 2008, Doxorubicin conjugated to d-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS): conjugation chemistry, characterization, in vitro and in vivo evaluation, Biomaterials, 29, 3856, 10.1016/j.biomaterials.2008.05.016

Mi, 2012, Vitamin E TPGS prodrug micelles for hydrophilic drug delivery with neuroprotective effects, Int. J. Pharm., 438, 98, 10.1016/j.ijpharm.2012.08.038

Mi, 2013, Targeted co-delivery of docetaxel, cisplatin and herceptin by vitamin E TPGS-cisplatin prodrug nanoparticles for multimodality treatment of cancer, J. Control. Release, 169, 185, 10.1016/j.jconrel.2013.01.035

Nielsen, 2001, The effect of alpha-tocopherol on the in vitro solubilisation of lipophilic drugs, Int. J. Pharm., 222, 217, 10.1016/S0378-5173(01)00701-3

Constantinides, 2004, A DFT study of the ground state multiplicities of linear vs angular polyheteroacenes, J. Am. Chem. Soc., 126, 16232, 10.1021/ja045006t

Chan, 2007, Review on Medusa:a polymer-based sustained release technology for protein and peptide drugs, Expert Opin. Drug Deliv., 4, 441, 10.1517/17425247.4.4.441

Zhang, 2007

Duhem, 2013, Self-assembling doxorubicin-tocopherol succinate prodrug as a new drug delivery system: synthesis, characterization, and in vitro and in vivo anticancer activity, Bioconjug. Chem., 25, 72, 10.1021/bc400326y

Eastman

Collnot, 2010, Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access, Mol. Pharm., 7, 642, 10.1021/mp900191s

OncoGenex Pharmaceuticals website

Medicalnewstoday website

Varma, 2005, Enhanced oral paclitaxel absorption with vitamin E-TPGS: effect on solubility and permeability in vitro, in situ and in vivo, Eur. J. Pharm. Sci., 25, 445, 10.1016/j.ejps.2005.04.003

Zhang, 2012, Influence of vitamin E tocopherol polyethylene glycol succinate 1000 on intestinal absorption of icariside II, Pharmazie, 67, 59

Muthu, 2012, Development of docetaxel-loaded vitamin E TPGS micelles: formulation optimization, effects on brain cancer cells and biodistribution in rats, Nanomedicine, 7, 353, 10.2217/nnm.11.111

Rachmawati, 2013, Development of curcumin nanocrystal: physical aspects, J. Pharm. Sci., 102, 204, 10.1002/jps.23335

Mu, 2003, A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGS, J. Control. Release, 86, 33, 10.1016/S0168-3659(02)00320-6

Feng, 2008, Nanoparticles of biodegradable polymers for cancer treatment, Biomaterials, 29, 4146, 10.1016/S0142-9612(08)00562-0