Vitamin D inhibits Fas ligand-induced apoptosis in human osteoblasts by regulating components of both the mitochondrial and Fas-related pathways

Bone - Tập 35 Số 1 - Trang 57-64 - 2004
Gustavo Duque1,2, Khadija El Abdaimi1, Janet E. Henderson3, Abderrahim Lomri4, Richard Kremer1,3
1Calcium Research Laboratory, McGill University, Montreal, Quebec, Canada H3A 1A1
2Division of Geriatric Medicine, McGill University, Montreal, Quebec, Canada H3T 1E2
3Centre for Bone and Periodontal Research, McGill University Health Centre, Montreal, Quebec, Canada H3A 1A1
4INSERM Unité 349, Lariboisière Hospital, Paris, France

Tóm tắt

Từ khóa


Tài liệu tham khảo

Goltzman, 2002, Discoveries, drugs and skeletal disorders, Nat. Rev., Drug Discov., 1, 784, 10.1038/nrd916

Chan, 2002, Age-related bone loss: old bone, new facts, Gerontology, 48, 62, 10.1159/000048929

Weinstein, 2000, Apoptosis and osteoporosis, Am. J. Med., 108, 153, 10.1016/S0002-9343(99)00420-9

Manolagas, 2000, Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis, Endocr. Rev., 21, 115, 10.1210/er.21.2.115

Duque, 2002, Estrogens (E2) regulate expression and response of 1,25-dihydroxyvitamin D3 receptors in bone cells: changes with aging and hormone deprivation, Biochem. Biophys. Res. Commun., 299, 446, 10.1016/S0006-291X(02)02657-8

Hughes, 1997, Apoptosis in bone physiology and disease, Mol. Pathol., 50, 132, 10.1136/mp.50.3.132

Hughes, 1996, Estrogen promotes apoptosis of murine osteoclasts mediated by TGFß, Nat. Med., 2, 1132, 10.1038/nm1096-1132

Weinstein, 2002, Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids, J. Clin. Invest., 109, 1041, 10.1172/JCI0214538

Hill, 1997, Multiple extracellular signals promote osteoblast survival and apoptosis, Endocrinology, 138, 3849, 10.1210/en.138.9.3849

Kawakami, 1997, Fas and Fas ligand interaction is necessary for human osteoblast apoptosis, J. Bone Miner. Res., 12, 1637, 10.1359/jbmr.1997.12.10.1637

Tsuboi, 1999, Fas and Fas ligand interaction is necessary for human osteoblast apoptosis, J. Lab. Clin. Med., 134, 222, 10.1016/S0022-2143(99)90201-9

Chao, 2002, Importance of FADD signaling in serum deprivation- and hypoxia-induced cardiomyocyte apoptosis, J. Biol. Chem., 277, 31639, 10.1074/jbc.M204104200

Kawakami, 1998, Insulin-like growth factor I stimulates proliferation and Fas-mediated apoptosis of human osteoblasts, Biochem. Biophys. Res. Commun., 247, 46, 10.1006/bbrc.1998.8728

Kischkel, 1995, Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signalling complex (DISC) with the receptor, EMBO J., 14, 5579, 10.1002/j.1460-2075.1995.tb00245.x

Ozeki, 2002, Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells, Arch. Oral Biol., 47, 511, 10.1016/S0003-9969(02)00035-3

Bang, 2000, Fas- and tumor necrosis factor-mediated apoptosis uses the same binding surface of FADD to trigger signal transduction, J. Biol. Chem., 275, 36217, 10.1074/jbc.M006620200

Norman, 1982, Intestinal calcium transport: pleiotropic effects mediated by vitamin D, Fed. Proc., 41, 78

Ozono, 1991, Perspectives: the genomic mechanism of action of 1,25-dihydroxyvitamin D3, J. Bone Miner. Res., 6, 1021, 10.1002/jbmr.5650061002

Clements, 1992, Importance of FADD signaling in serum deprivation- and hypoxia-induced cardiomyocyte apoptosis, Clin. Endocrinol. (Oxf.), 37, 17, 10.1111/j.1365-2265.1992.tb02278.x

Lips, 2001, Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications, Endocr. Rev., 22, 477, 10.1210/er.22.4.477

Burgess, 1999, The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts, J. Cell Biol., 145, 527, 10.1083/jcb.145.3.527

O'Brien, 1999, Identification of an OSF-2 binding site in the murine RANKL/OPGL gene promoter: a potential link between osteoblastogenesis and osteoclastogenesis, J. Biol. Chem., 274, 19301, 10.1074/jbc.274.27.19301

De Pollack, 1996, Increased bone formation and osteoblastic cell phenotype in premature cranial suture ossification (craniosynostosis), J. Bone Miner. Res., 11, 401, 10.1002/jbmr.5650110314

Lomri, 1999, Genomic insertion of the SV-40 large T oncogene in normal adult human trabecular osteoblastic cells induces cell growth without loss of the differentiated phenotype, Calcif. Tissue Int., 64, 394, 10.1007/PL00005821

Lomri, 1997, Expression of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor in newborn human calvaria osteoblastic cells, Eur. J. Endocrinol., 136, 640, 10.1530/eje.0.1360640

Gavrieli, 1992, Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation, J. Cell Biol., 119, 493, 10.1083/jcb.119.3.493

Jilka, 1999, Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone, J. Clin. Invest., 104, 439, 10.1172/JCI6610

Luckman, 1998, Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras, J. Bone Miner. Res., 13, 581, 10.1359/jbmr.1998.13.4.581

Goldstein, 1990, Regulation of mevalonate pathway, Nature, 343, 425, 10.1038/343425a0

Manolagas, 2002, Sex steroids and bone, Recent Prog. Horm. Res., 57, 385, 10.1210/rp.57.1.385

Cooper, 2000, Estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression, J. Cell. Physiol., 185, 401, 10.1002/1097-4652(200012)185:3<401::AID-JCP10>3.0.CO;2-C

Jilka, 1998, Osteoblast programmed cell death (Apoptosis): modulation by growth factors and cytokines, J. Bone Miner. Res., 13, 793, 10.1359/jbmr.1998.13.5.793

Urayama, 2000, Effect of vitamin K2 on osteoblast apoptosis: vitamin K2 inhibits apoptotic cell death of human osteoblasts induced by Fas, proteasome inhibitor, etoposide, and staurosporine, J. Lab. Clin. Med., 136, 181, 10.1067/mlc.2000.108754

Schilli, 1998, Reduction of intrafollicular apoptosis in chemotherapy-induced alopecia by topical calcitriol-analogs, J. Invest. Dermatol., 111, 598, 10.1046/j.1523-1747.1998.00350.x

Niikura, 2002, Monitoring of caspase-8/FLICE processing and activation upon Fas stimulation with novel antibodies directed against a cleavage site for caspase-8 and its substrate, FLICE-like inhibitory protein (FLIP), J. Biochem. (Tokyo), 132, 53, 10.1093/oxfordjournals.jbchem.a003198

Hansen, 2001, Vitamin D compounds exert anti-apoptotic effects in human osteosarcoma cells in vitro, J. Steroid Biochem. Mol. Biol., 77, 1, 10.1016/S0960-0760(01)00033-4

Smulson, 2000, Roles of poly (ADP-ribosylation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1, Adv. Enzyme Regul., 40, 183, 10.1016/S0065-2571(99)00024-2

Xu, 2000, p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4, Biochem. Biophys. Res. Commun., 269, 179, 10.1006/bbrc.2000.2247

Suzuki, 1998, Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP, Oncogene, 17, 931, 10.1038/sj.onc.1202021

Bellido, 1998, Transcriptional activation of the p21 (WAF1, CIP1, SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells, J. Biol. Chem., 273, 21137, 10.1074/jbc.273.33.21137

Bellosta, 2003, p21 (WAF1/CIP1) acts as a brake in osteoblast differentiation, J. Bone Miner. Res., 18, 818, 10.1359/jbmr.2003.18.5.818