Vitamin D analogs: Actions and role in the treatment of secondary hyperparathyroidism

Seminars in Nephrology - Tập 24 - Trang 456-459 - 2004
Kevin J. Martin1, Esther A. González1
1Division of Nephrology, Department of Internal Medicine, St. Louis University, St. Louis, MO USA.

Tài liệu tham khảo

González, 1995, Renal osteodystrophy, Nephrol Dial Transplant, 10, 13, 10.1093/ndt/10.supp3.13 Slatopolsky, 1999, Pathogenesis of secondary hyperparathyroidism, Kidney Int Suppl, 73, S14, 10.1046/j.1523-1755.1999.07304.x Slatopolsky, 2001, Role of phosphorus in the pathogenesis of secondary hyperparathyroidism, Am J Kidney Dis, 37, S54, 10.1053/ajkd.2001.20740 Silver, 1986, Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat, J Clin Invest, 78, 1296, 10.1172/JCI112714 Russell, 1986, Suppression by 1,25(OH)2D3 of transcription of the pre-proparathyroid hormone gene, Endocrinology, 119, 2864, 10.1210/endo-119-6-2864 Cantley, 1985, 1,25-dihydroxyvitamin D3 suppresses parathyroid hormone secretion from bovine parathyroid cells in tissue culture, Endocrinology, 117, 2114, 10.1210/endo-117-5-2114 Kremer, 1989, Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells, Endocrinology, 125, 935, 10.1210/endo-125-2-935 Andress, 1989, Intravenous calcitriol in the treatment of refractory osteitis fibrosa of chronic renal failure, N Engl J Med, 321, 274, 10.1056/NEJM198908033210502 Slatopolsky, 1984, Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients, J Clin Invest, 74, 2136, 10.1172/JCI111639 Quarles, 1994, Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD, Kidney Int, 45, 1710, 10.1038/ki.1994.223 Delmez, 1992, Hyperphosphatemia, Am J Kidney Dis, 19, 303, 10.1016/S0272-6386(12)80446-X Brown, 1999, Vitamin D analogs, Miner Electrolyte Metab, 25, 337, 10.1159/000057470 Slatopolsky, 1995, A new analog of calcitriol, 19-nor-1,25-(OH)2D2, suppresses parathyroid hormone secretion in uremic rats in the absence of hypercalcemia, Am J Kidney Dis, 26, 852, 10.1016/0272-6386(95)90455-7 Finch, 1999, Differential effects of 1,25-dihydroxy-vitamin D3 and 19-nor-1,25-dihydroxy-vitamin D2 on calcium and phosphorus resorption in bone, J Am Soc Nephrol, 10, 980, 10.1681/ASN.V105980 Takahashi, 1997, A new analog of 1,25-(OH)2D3, 19-NOR-1,25-(OH)2D2, suppresses serum PTH and parathyroid gland growth in uremic rats without elevation of intestinal vitamin D receptor content, Am J Kidney Dis, 30, 105, 10.1016/S0272-6386(97)90571-0 Martin, 1998, 19-Nor-1-a-25-dihydroxyvitamin D2 (paricalcitol) safely and effectively reduces the levels of intact PTH in patients on hemodialysis, J Am Soc Nephrol, 9, 1427, 10.1681/ASN.V981427 Lindberg, 2001, A long-term, multicenter study of the efficacy and safety of paricalcitol in end-stage renal disease, Clin Nephrol, 56, 315 Martin, 1998, Therapy of secondary hyperparathyroidism with 19-nor-1alpha,25-dihydroxyvitamin D2, Am J Kidney Dis, 32, S61, 10.1053/ajkd.1998.v32.pm9808145 Coyne, 2002, Differential effects of acute administration of 19-Nor-1,25-dihydroxy-vitamin D2 and 1,25-dihydroxy-vitamin D3 on serum calcium and phosphorus in hemodialysis patients, Am J Kidney Dis, 40, 1283, 10.1053/ajkd.2002.36899 Sprague, 2001, Suppression of parathyroid hormone secretion in hemodialysis patients, Am J Kidney Dis, 38, S51, 10.1053/ajkd.2001.28110 Teng, 2003, Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy, N Engl J Med, 349, 446, 10.1056/NEJMoa022536 Kobayashi, 1994, The binding properties, with blood proteins, and tissue distribution of 22-oxa-1 alpha,25-dihydroxyvitamin D3, a noncalcemic analogue of 1 alpha, 25-dihydroxyvitamin D3, in rats, J Biochem (Tokyo), 115, 373, 10.1093/oxfordjournals.jbchem.a124346 Okano, 1989, Protein-binding properties of 22-oxa-1 alpha,25-dihydroxyvitamin D3, a synthetic analogue of 1 alpha,25-dihydroxyvitamin D3, J Nutr Sci Vitaminol (Tokyo), 35, 529, 10.3177/jnsv.35.529 Dusso, 1991, On the mechanisms for the selective action of vitamin D analogs, Endocrinology, 128, 1687, 10.1210/endo-128-4-1687 Yasuda, 2003, Multicenter clinical trial of 22-oxa-1,25-dihydroxyvitamin D3 for chronic dialysis patients, Am J Kidney Dis, 41, S108, 10.1053/ajkd.2003.50097 Akizawa, 2002, Long-term effect of 1,25-dihydroxy-22-oxavitamin D(3) on secondary hyperparathyroidism in haemodialysis patients. One-year administration study, Nephrol Dial Transplant, 17, 28, 10.1093/ndt/17.suppl_10.28 Hirata, 2003, In subtotally nephrectomized rats 22-oxacalcitriol suppresses parathyroid hormone with less risk of cardiovascular calcification or deterioration of residual renal function than 1,25(OH)(2) vitamin D(3), Nephrol Dial Transplant, 18, 1770, 10.1093/ndt/gfg296 Monier-Faugere, 1999, 22-oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure, Kidney Int, 55, 821, 10.1046/j.1523-1755.1999.055003821.x Tsukamoto, 2000, Effect of 22-oxacalcitriol on bone histology of hemodialyzed patients with severe secondary hyperparathyroidism, Am J Kidney Dis, 35, 458, 10.1016/S0272-6386(00)70198-3 Komuro, 1999, In vivo and in vitro pharmacokinetics and metabolism studies of 26,26,26,27,27,27-F6-1,25(OH)2 vitamin D3 (Falecalcitriol) in rat, Xenobiotica, 29, 603, 10.1080/004982599238425 Akiba, 1998, Controlled trial of falecalcitriol versus alfacalcidol in suppression of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism, Am J Kidney Dis, 32, 238, 10.1053/ajkd.1998.v32.pm9708607 Ritzerfeld, 2001, Alfacalcidol in the therapy of renal bone disease, Int J Clin Pharmacol Ther, 39, 546, 10.5414/CPP39546 Avioli, 1999, Vitamin D and the D-hormones, alfacalcidol and calcitriol, as therapeutic agents for osteoporotic populations, Calcif Tissue Int, 65, 292, 10.1007/s002239900701 Hamdy, 1995, Effect of alfacalcidol on natural course of renal bone disease in mild to moderate renal failure, BMJ, 310, 358, 10.1136/bmj.310.6976.358 Lee, 1994, A comparison of oral and intravenous alfacalcidol in the treatment of uremic hyperparathyroidism, J Am Soc Nephrol, 5, 1344, 10.1681/ASN.V561344 Sharman, 1982, Long-term experience of alfacalcidol in renal osteodystrophy, QJM, 51, 271 Sjoden, 1985, 1 alpha-Hydroxyvitamin D2 is less toxic than 1 alpha-hydroxyvitamin D3 in the rat, Proc Soc Exp Biol Med, 178, 432, 10.3181/00379727-178-42028 Sjoden, 1984, Antirachitic activity of 1 alpha-hydroxyergocalciferol and 1 alpha-hydroxycholecalciferol in rats, J Nutr, 114, 2043, 10.1093/jn/114.11.2043 Mawer, 1998, Unique 24-hydroxylated metabolites represent a significant pathway of metabolism of vitamin D2 in humans, J Clin Endocrinol Metab, 83, 2156, 10.1210/jc.83.6.2156 Frazao, 2000, Intermittent doxercalciferol (1alpha-hydroxyvitamin D(2)) therapy for secondary hyperparathyroidism, Am J Kidney Dis, 36, 550, 10.1053/ajkd.2000.16193 Maung, 2001, Efficacy and side effects of intermittent intravenous and oral doxercalciferol (1alpha-hydroxyvitamin D(2)) in dialysis patients with secondary hyperparathyroidism, Am J Kidney Dis, 37, 532, 10.1016/S0272-6386(01)80010-X