Videostroboscopy, Laryngopharyngeal Reflux, and Dysphonia: A Complex Relationship
Tóm tắt
The role of laryngoscopic examination in the diagnosis of reflux disease is controversial. Though some studies support exam findings such as laryngeal edema and erythema as supportive of a reflux diagnosis, and though many otolaryngologists continue to use these exam findings to establish a clinical diagnosis of laryngopharyngeal reflux (LPR), critical review of laryngoscopic exam has called this approach into question. The role of laryngoscopic exam as related to reflux may not be in establishing a reflux diagnosis, but instead in evaluating for other causes of the patient’s complaints. This is particularly important when the chief complaint is dysphonia, where videostroboscopy has been demonstrated to be a more effective approach in addressing dysphonia than anti-reflux medication prescribed on the basis of non-stroboscopic laryngeal exam. This article aims to critically analyze the association of LPR with dysphonia, examine how videostroboscopy interfaces with this association of LPR/dysphonia, and review current practice patterns in order to improve management of patients with dysphonia.
Tài liệu tham khảo
• Koufman JA. The Otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope. 1991;101(Suppl. 53):1–78. One of the first papers published that established the role of laryngopharyngeal reflux in Otolaryngology.
Koufman J. Laryngopharyngeal reflux is different from classic gastroesophageal reflux disease. Ear Nose Throat J. 2002;81:9.
Koufman J, Amin M, Panetti M. Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders. Otolaryngol Head Neck Surg. 2000;123:385–8.
Koufman J, Aviv J, Casiano R, Shaw G. Laryngopharyngeal reflux: position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-Head And Neck Surgery. Otolaryngol Head Neck Surg. 2002;127:32–5.
Balefsky PC, et al. The association between laryngeal pseudosulcus and laryngopharyngeal reflux. Otolaryngol Head Neck Surg. 2002;126(6):649–52.
• Gooi Z, Ishman SL, Bock JM, Blumin JH, Akst LM. Laryngopharyngeal reflux: paradigms for evaluation, diagnosis, and treatment. Ann Otol Rhinol Laryngol. 2014;123(10):677–85. One of the two ABEA survey regarding LPR and treatment in Otolaryngology.
• Gooi Z, Ishman SL, Bock JM, Blumin JH, Akst LM. Changing patterns in reflux care: 10-year comparison of ABEA members. Ann Otol Rhinol Laryngol. 2015. One of two ABEA survey regarding LPR and treatment in Otolaryngology.
Rafii B, Taliercio S, Achlatis S, Ruiz R, Amin M, Branski R. Incidence of underlying laryngeal pathology in patients initially diagnosed with laryngopharyngeal reflux. Laryngoscope. 2013;124:1420–4.
Park, et al. Laryngopharyngeal reflux: prospective cohort study evaluating optimal dose of proton-pump inhibitor therapy and pretherapy predictors of response. Laryngoscope. 2005;115:1230–8.
Jin, et al. Change of acoustic parameters before and after treatment in laryngopharyngeal reflux patients. Laryngoscope. 2008;118:938–41.
• Milstein C, Charble S, Hicks D, Abelson T, Richter J, Vaezi M. Prevalence of laryngeal irritation signs associated with reflux in asymptomatic volunteers: impact of endoscopic technique (rigid vs. flexible laryngoscope). Laryngoscope. 2005;115:2256–61. One of the first papers to break down the paradigm of laryngeal findings in diagnosis of LPR.
Powell J, et al. Mucosal changes in laryngopharyngeal reflux—prevalence, sensitivity, specificity and assessment. Laryngoscope. 2012;123:985–91.
Shapiro, et al. The reliability of the assessment of endoscopic laryngeal findings associated with laryngopharyngeal reflux disease. Laryngoscope. 2002;112:1019–24.
Branski R, et al. Diagnostic accuracy of history, laryngoscopy, and stroboscopy. Laryngoscope. 2012;123:215–9.
•• Sulica L. Laryngoscopy, stroboscopy and other tools for the evaluation of voice disorders. Otolaryngol Clin N Am. 2013;46:21–30. Well established review of Laryngoscopy, Stroboscopy and evaluation of Voice Disorders.
Karkos PD, Wilson JA, et al. Empiric treatment of laryngopharyngeal reflux with proton pump inhibitors: a systematic review. Laryngoscope. 2006;116:144–8.
Noordzji JP, et al. Correlation of pH probe-measured laryngopharyngeal reflux with symptoms and signs of reflux laryngitis. Laryngoscope. 2002;112:2191–5.
Hamdan L, et al. Effect of aggressive therapy on laryngeal symptoms and voice characteristics in patients with gastroesophageal reflux. Acta Otolaryngol. 2001;121:868–72.
• Qadeer MA, et al. Proton pump inhibitor therapy for suspected gerd-related chronic laryngitis: a meta-analysis of randomized controlled trials. Am J Gastroentol 2006;101:2646–54. one of the largest meta analysis regarding PPI therapy and chronic laryngitis.
•• Kahrilas, P, Shaheen N, Vaezi M. Gastroesophageal reflux disease (GERD). 2008. AGA guidelines on GERD and treatment (published in 2008).
•• Schwartz SR, Cohen SM, Dailey SH, et al. Clinical practice guidelines: hoarseness (dysphonia). Otolaryngol Head Neck Surg. 2009;141:S1–31. AAO guidelines on clinical practice guidelines for Otolaryngologists with regards to dysphonia.
•• Katz, P, Gerson, L, Vela, M. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol 2013;108:308–28. ACGI guidelines in gasteroenterology regarding treatment of GERD.
Ruiz R, Jeswani S, Andrews K, et al. Hoarseness and laryngopharyngeal reflux a survey of primary care physician practice patterns. JAMA. 2014;140:192–6.
Cohen SM, Pitman MJ, Noordzij JP, Courey M. Management of dysphonic patients by otolaryngologists. Otolaryngol Head Neck Surg. 2012;147(2):289–94.
Cohen SM, Pitman MJ, Noordzij JP, Courey M. Evaluation of dysphonic patients by general otolaryngologists. J Voice. 2012;26:772–8.
Cohen SM. Self-reported impact of dysphonia in a primary care population: an epidemiological study. Laryngoscope. 2010;120:2022–32.
•• Sulica L. Hoarseness misattributed to reflux: sources and patterns of error. Ann Otol Rhinol Laryngol. 2014;123(6):442–5. Review of the poor association between dysphonia and reflux.
Cohen SM, Courey M. Frequency and factors associated with use of videolaryngostroboscopy in voice disorder assessment. Laryngoscope. 2014;124:2118–24.
•• Fritz et al. The accuracy of the laryngopharyngeal reflux diagnosis-utility of the stroboscopic exam. In: 2013 Fall voice conference. Atlanta (in press). Most current review regarding the role of stroboscopy and how it is involved in LPR diagnosis.
Sataloff RT, et al. Strobovideolaryngoscopy: results and clinical value. Ann Otol Rhinol Laryngol. 1991;100(9 pt 1):725–7.
• Cohen, SM, Garrett, C et al. Hoarseness: is it really laryngopharyngeal reflux? Laryngoscope. 2008;118:363–6. Good review that showed hoarseness as related to other etiologies, and when once treated, improved without PPI.