Versatile synthetic approach to new bifunctional chelating agents tailor made for labeling with the fac-[M(CO)3]+ core (M = Tc, 99mTc, Re): synthesis, in vitro, and in vivo behavior of the model complex [M(APPA)(CO)3] (appa = [(5-amino-pentyl)-pyridin-2-yl-methyl-amino]-acetic acid)
Albert Stichelberger1, Robert Waibel1, Cécile Dumas1, P.A Schubiger1, Roger Schibli1
1Center for Radiopharmaceutical Science of the ETH Zürich, Paul Scherrer Institute Villigen and the University Hospital Zürich, CH-5232 Villigen, Switzerland