Vascular permeability in cancer and infection as related to macromolecular drug delivery, with emphasis on the EPR effect for tumor-selective drug targeting

Hiroshi Maeda1
1Institute of Drug Delivery System Research, School of Pharmaceutical Sciences, Sojo University

Tóm tắt

Từ khóa


Tài liệu tham khảo

1984, J. Biochem., 96, 739, 10.1093/oxfordjournals.jbchem.a134892

Kamata, R., Yamamoto, T., Matsumoto, 1985, Infect. Immun., 48, 747, 10.1128/IAI.48.3.747-753.1985

1989, J. Biol. Chem., 264, 10589, 10.1016/S0021-9258(18)81661-1

1993, J. Biol. Chem., 268, 17711, 10.1016/S0021-9258(17)46762-7

5) Maeda, H. (2002) Microbial proteinases and pathogenesis of infection. <i>In</i> The Encyclopedia of Molecular Medicine, vol. 4 (ed. Creighton, T.E.). John Wiley &amp; Sons, New York, pp. 2663&ndash;2668.

MAEDA H, 1996, Microbiol. Immunol., 40, 685, 10.1111/j.1348-0421.1996.tb01129.x

1988, J. Biol. Chem., 263, 16051, 10.1016/S0021-9258(18)37555-0

MATSUMURA Y, 1988, Jpn. J. Cancer Res., 79, 1327, 10.1111/j.1349-7006.1988.tb01563.x

MATSUMURA Y, 1991, Jpn. J. Cancer Res., 82, 732, 10.1111/j.1349-7006.1991.tb01910.x

10.1016/S0162-3109(99)00104-6

MAEDA H, 1994, Jpn. J. Cancer Res., 85, 331, 10.1111/j.1349-7006.1994.tb02362.x

WU J, 2001, Jpn. J. Cancer Res., 92, 439, 10.1111/j.1349-7006.2001.tb01114.x

1998, Cancer Res., 58, 159

10.1006/abbi.1997.0127

10.1016/S1567-5769(02)00271-0

10.1016/0162-3109(96)00063-X

17) Maeda, H., Takeshita, J. and Kanamaru, R. (1979) A lipophilic derivative of neocarzinostatin: A polymer conjugation of an antitumor protein antibiotic. Int. J. Pept. Protein Res. <b>14</b>, 81&ndash;87.

10.1021/jm00382a012

1984, Cancer Res., 44, 2115

1987, Anticancer Res., 7, 321

21) Courtice, F.C. (1996) The origin of lipoproteins in lymph. <i>In</i> Lymph and Lymphatic System (ed. Mayerson). Charles C Thomas Publisher, Springfield, IL, pp. 89&ndash;126.

Maeda, H., Takeshita, J. and Yamash, 1980, Eur. J. Cancer, 16, 723, 10.1016/0014-2964(80)90215-7

1982, Gann, 73, 278

10.1016/0277-5379(83)90028-7

25) Konno, T., Maeda, H., Iwai, K., Maki, S., Tashiro, S., Uchida, M. and Miyauchi, Y. (1984) Selective targeting of anticancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium. Cancer <b>54</b>, 2367&ndash;2374.

26) Maki, S., Konno, T. and Maeda, H. (1985) Image enhancement in computerized tomography for sensitive diagnosis of liver cancer and semiquantitation of tumor selective drug targeting with oily contrast medium. Cancer <b>56</b>, 751&ndash;757.

Matsumura, Y. and Maeda, H., 1986, Cancer Res., 46, 6387

NOGUCHI Y, 1998, Jpn. J. Cancer Res., 89, 307, 10.1111/j.1349-7006.1998.tb00563.x

Seymour, L.W., Miyamoto, Y., Maeda,, 1995, Eur. J. Cancer, 31, 766, 10.1016/0959-8049(94)00514-6

10.1016/S0168-3659(99)00248-5

10.1016/S0168-3659(01)00309-1

32) Maeda, H. (2001) The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. <b>41</b>, 189&ndash;207.

Maeda, H. and Matsumura, Y., 1989, Crit. Rev. Ther. Drug Carrier Syst., 6, 193

10.1016/j.ejpb.2008.11.010

10.1021/bc100070g

36) Maeda, H. (2011) The EPR-effect in relation to tumor targeting. <i>In</i> Drug Delivery in Oncology. From Basic Research to Cancer Therapy (eds. Kratz, F., Senter, P. and Steinhagen, H.). Wiley-VCH Verlag GmbH &amp; Co. KG, Weinheim, Germany, pp. 65&ndash;86.

Kimura, N., Taniguchi, S., Aoki, K., 1980, Cancer Res., 40, 2061

10.1073/pnas.0408422102

Hoffman, R.M., 2009, Amino Acids, 37, 509, 10.1007/s00726-009-0261-8

40) Konerding, M.A., Miodonski, A.J. and Lametschwandtner, A. (1995) Microvascular corrosion casting in the study of tumor vascularity: a review. Scanning Microsc. <b>9</b>, 1233&ndash;1244.

Hashizume, H., Baluk, P., Morikawa,, 2000, Am. J. Pathol., 1561, 1363, 10.1016/S0002-9440(10)65006-7

1990, Cancer Res., 50, 2411

Malcontenti-Wilson, C., Muralidhara, 2001, Clin. Cancer Res., 7, 1052

10.1111/j.1349-7006.2010.01619.x

10.1056/NEJM197111182852108

46) Folkman, J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst. <b>82</b>, 4&ndash;6.

47) Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. <b>1</b>, 27&ndash;31.

10.1126/science.6823562

Dvorak, H.F., Nagy, J.A., Dvorak, J, 1988, Am. J. Pathol., 133, 95

Dvorak, H.F., Brown, L.F., Detmar,, 1995, Am. J. Pathol., 146, 1029

10.1126/science.2479986

Miller, J.W., Adamis, A.P., Shima,, 1994, Am. J. Pathol., 145, 574

Dvorak, H.F., Nagy, J.A., Feng, D.,, 1999, Curr. Top. Microbiol. Immunol., 237, 97, 10.1007/978-3-642-59953-8_6

10.1126/science.2543070

10.1172/JCI114499

1991, Proc. Soc. Exp. Biol. Med., 198, 721, 10.3181/00379727-198-43309C

10.1073/pnas.93.6.2448

10.1096/fj.14.10.1447

59) Akaike, T. and Maeda, H. (2000) Pathophysiological effects of high-output production of nitric oxide. <i>In</i> Nitric Oxide (ed. Ignarro, L.J.). Academic Press, San Diego, pp. 733&ndash;745.

1998, Proc. Soc. Exp. Biol. Med., 217, 64, 10.3181/00379727-217-44206

Umezawa, K., Akaike, T., Fujii, S.,, 1997, Infect. Immun., 65, 2932, 10.1128/IAI.65.7.2932-2940.1997

10.1128/JVI.78.16.8709-8719.2004

63) Doi, K., Akaike, T., Horie, H., Noguchi, Y., Fujii, S., Beppu, T., Ogawa, M. and Maeda, H. (1996) Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth. Cancer <b>77</b>, 1598&ndash;1604.

10.1021/jf040045+

10.1111/j.1348-0421.2008.00089.x

10.1016/j.niox.2005.06.005

10.1016/j.niox.2005.11.001

10.1016/S0304-3835(99)00139-1

10.1126/science.1133427

10.1126/science.1145720

10.1038/nature08489

72) Fojo, T. and Grady, C. (2009) How much is life worth: cetuximab, non&ndash;small cell lung cancer, and the $440 billion question. J. Natl. Cancer Inst. <b>101</b>, 1044&ndash;1048.

Mayer, R., 2009, N. Engl. J. Med., 360, 623, 10.1056/NEJMe0809343

Anonymous, 2008, Lancet, 372, 601, 10.1016/S0140-6736(08)61249-0

Tol, J., Koopman, M., Cats, A., Rod, 2009, N. Engl. J. Med., 360, 563, 10.1056/NEJMoa0808268

10.1073/pnas.0611660104

HUANG S, 2000, Cancer Res., 60, 5334

Tanaka, S., Akaike, T., Wu, J., Fan, 2003, J. Drug Target., 11, 45, 10.1080/1061186031000086072

10.1038/sj.bjc.6690624

80) Fang, J., Qin, H., Nakamura, H., Tsukigawa, K. and Maeda, H. (2012) Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention (EPR) effect of solid tumor. Cancer Sci. <b>103</b> (in press available online, Jan. 2012).

Sahoo, S.K., Sawa, T., Fang, J., Ta, 2002, Bioconjug. Chem., 13, 1031, 10.1021/bc020010k

Fang, J., Sawa, T., Akaike, T., Aku, 2003, Cancer Res., 63, 3567

Fang, J., Akaike, T. and Maeda, H., 2004, Apoptosis, 9, 27, 10.1023/B:APPT.0000012119.83734.4e

Daruwalla, J., Greish, K., Wilson,, 2009, J. Vasc. Res., 46, 218, 10.1159/000165380

85) Suzuki, M., Hori, K., Abe, I., Saito, S. and Sato, H. (1981) A new approach to cancer chemotherapy: selective enhancement of tumor blood flow with angiotensin II. J. Natl. Cancer Inst. <b>67</b>, 663&ndash;669.

HORI K, 1991, Jpn. J. Cancer Res., 82, 1309, 10.1111/j.1349-7006.1991.tb01797.x

87) Li, C.J., Miyamoto, Y., Kojima, Y. and Maeda, H. (1993) Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure. Br. J. Cacner <b>67</b>, 975&ndash;980.

88) Nagamitsu, A., Greish, K. and Maeda, H. (2009) Elevating blood pressure as a strategy to increase tumor targeted delivery of macromolecular drug SMANCS: cases of advanced solid tumors. Jpn. J. Clin. Oncol. <b>39</b>, 756&ndash;766.

10.1111/j.1349-7006.2009.01323.x

Maeda, H., 2010, J. Control. Release, 142, 296, 10.1016/j.jconrel.2010.01.002

10.1016/0014-2999(87)90493-6

92) Fukuto, J.M., Cho, J.Y. and Switzer, C.H. (2000) The chemical properties of nitric oxide and related nitrogen oxides. <i>In</i> Nitric Oxide: Biology and Pathobiology (ed. Ignarro, L.J.). Academic Press, San Diego, pp. 23&ndash;39.

1993, Cancer Res., 53, 5845

Yasuda, H., Yamaya, M., Nakayama, K, 2006, J. Clin. Oncol., 24, 688, 10.1200/JCO.2005.04.0436

Yasuda, H., Nakayama, K., Watanabe,, 2006, Clin. Cancer Res., 12, 6748, 10.1158/1078-0432.CCR-06-1124

96) Yasuda, H., Yanagihara, K., Nakayama, K., Mio, T., Sasaki, T., Asada, M., Yamaya, M. and Fukushima, M. (2010) Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies. <i>In</i> Nitric Oxide and Cancer (ed. Bonavida, B.). Springer Science, New York, pp. 419&ndash;441.

Siemens, D.R., Heaton, J.P.W., Adam, 2009, Urology, 74, 878, 10.1016/j.urology.2009.03.004

Jordan, B.F., Misson, P.D., Remeure, 2000, Int. J. Radiat. Oncol. Biol. Phys., 48, 565, 10.1016/S0360-3016(00)00694-5

NOGUCHI A, 1992, Jpn. J. Cancer Res., 83, 240, 10.1111/j.1349-7006.1992.tb00093.x

Hori, K., Saito, S., Takahashi, H.,, 2000, Jpn. J. Cancer Res., 91, 261, 10.1111/j.1349-7006.2000.tb00940.x