Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation

Fedak, 2002, Clinical and pathophysiological implications of a bicuspid aortic valve, Circulation, 106, 900, 10.1161/01.CIR.0000027905.26586.E8

Dingemans, 2000, Extracellular matrix of the human aortic media, Anat Rec, 258, 1, 10.1002/(SICI)1097-0185(20000101)258:1<1::AID-AR1>3.0.CO;2-7

Bunton, 2001, Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome, Circ Res, 88, 37, 10.1161/01.RES.88.1.37

Milewicz, 1996, Fibrillin-1 (FBN1) mutations in patients with thoracic aortic aneurysms, Circulation, 94, 2708, 10.1161/01.CIR.94.11.2708

Braverman, 1996, Bicuspid aortic valve and associated aortic wall abnormalities, Curr Opin Cardiol, 11, 501, 10.1097/00001573-199609000-00009

Godfrey, 1993, Elastin and fibrillin mRNA and protein levels in the ontogeny of normal human aorta, Connect Tissue Res, 29, 61, 10.3109/03008209309061967

Strauss, 1994, Extracellular matrix remodeling after balloon angioplasty injury in a rabbit model of restenosis, Circ Res, 75, 650, 10.1161/01.RES.75.4.650

LaBourene, 1990, Circ Res, 66, 438, 10.1161/01.RES.66.2.438

Cruz, 1990, Inverse correlation between tyrosine phosphorylation and collagenase production in chondrocytes, Biochem J, 269, 717, 10.1042/bj2690717

de Sa, 1999, Histologic abnormalities of the ascending aorta and pulmonary trunk in patients with bicuspid aortic valve disease, J Thorac Cardiovasc Surg, 118, 588, 10.1016/S0022-5223(99)70002-4

Niwa, 2001, Structural abnormalities of great arterial walls in congenital heart disease, Circulation, 103, 393, 10.1161/01.CIR.103.3.393

Ramirez, 1999, Marfan syndrome, Ann Med, 31, 202, 10.3109/07853899909115979

Pereira, 1999, Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1, Proc Natl Acad Sci U S A, 96, 3819, 10.1073/pnas.96.7.3819

Pereira, 1997, Targeting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome, Nat Genet, 17, 218, 10.1038/ng1097-218

Bonderman, 1999, Mechanisms underlying aortic dilatation in congenital aortic valve malformation, Circulation, 99, 2138, 10.1161/01.CIR.99.16.2138

Osakabe, 2000, Quantitative changes of elastin, fibrillin and collagen in abdominal aortic aneurysms, Nippon Ronen Igakkai Zasshi, 37, 979, 10.3143/geriatrics.37.979

Ashworth, 1999, Fibrillin degradation by matrix metalloproteinases, Biochem J, 340, 171, 10.1042/bj3400171

Francke, 1995, A Gly1127Ser mutation in an EGF-like domain of the fibrillin-1 gene is a risk factor for ascending aortic aneurysm and dissection, Am J Hum Genet, 56, 1287

Montgomery, 1998, Multiple molecular mechanisms underlying subdiagnostic variants of Marfan syndrome, Am J Hum Genet, 63, 1703, 10.1086/302144

Davis, 1994, Immunolocalization of microfibril and microfibril-associated proteins in the subendothelial matrix of the developing mouse aorta, J Cell Sci, 107, 727, 10.1242/jcs.107.3.727

Eisenberg, 1995, Molecular regulation of atrioventricular valvuloseptal morphogenesis, Circ Res, 77, 1, 10.1161/01.RES.77.1.1

Epstein, 2000, Transcriptional regulation of cardiac development, Pediatr Res, 48, 717, 10.1203/00006450-200012000-00003

Longo, 2002, Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms, J Clin Invest, 110, 625, 10.1172/JCI0215334

Crowther, 2000, Increased matrix metalloproteinase 2 expression in vascular smooth muscle cells cultured from abdominal aortic aneurysms, J Vasc Surg, 32, 575, 10.1067/mva.2000.108010

Davis, 1998, Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms, Arterioscler Thromb Vasc Biol, 18, 1625, 10.1161/01.ATV.18.10.1625

Goodall, 2001, Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms, Circulation, 104, 304, 10.1161/01.CIR.104.3.304

McMillan, 1997, Size matters, Circulation, 96, 2228, 10.1161/01.CIR.96.7.2228

Segura, 1998, Immunohistochemistry of matrix metalloproteinases and their inhibitors in thoracic aortic aneurysms and aortic valves of patients with Marfan’s syndrome, Circulation, 98, II331

David, 2000, Dilation of the pulmonary autograft after the Ross procedure, J Thorac Cardiovasc Surg, 119, 210, 10.1016/S0022-5223(00)70175-9

Allaire, 1998, Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model, J Clin Invest, 102, 1413, 10.1172/JCI2909