Variation in susceptibility to experimental dermatomycosis in genetic strains of mice, I. Preliminary studies
Tóm tắt
Results of a preliminary study of the degree of susceptibility of two inbred mouse strains (C 57 B1/6 and DBA2) and the F1 progeny (BDF1) of these lines are reported. The possible significance of our findings are discussed in respect to the published accounts of the influence of the age, physiological response mechanisms, and immunological defense mechanisms of the suscept host and the age and strain of the fungus and the size of the inoculum. The possibility of theTrichophyton mentagrophytes carriers being animals that had the disease several times in the past, resulting in immunity or a high degree of resistance, is suggested. The results of this study have indicated several technical refinements which will be incorporated into subsequent experiments.
Tài liệu tham khảo
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