Vanillin exerts therapeutic effects against hyperglycemia-altered glucose metabolism and purinergic activities in testicular tissues of diabetic rats

Reproductive Toxicology - Tập 102 - Trang 24-34 - 2021
Veronica F. Salau1,2, Ochuko L. Erukainure1,3, Kolawole A. Olofinsan1, Md. Shahidul Islam1
1Department of Biochemistry, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa
2Department of Biochemistry, Veritas University, Bwari, Abuja, Nigeria
3Department of Pharmacology, University of the Free State, Bloemfontein 9300, South Africa

Tài liệu tham khảo

Maresch, 2018, Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review, Hum. Reprod. Update, 24, 86, 10.1093/humupd/dmx033 Basmatzou, 2016, Diabetes mellitus and influences on human fertility, Int. J. Caring Sci., 9, 371 itken, 2009, Antioxidant systems and oxidative stress in the testes, 154 Dkhil, 2016, Selenium nanoparticles attenuate oxidative stress and testicular damage in streptozotocin-induced diabetic rats, Molecules, 21, 1517, 10.3390/molecules21111517 Erukainure, 2019, Raffia palm (Raphia hookeri) wine extenuates redox imbalance and modulates activities of glycolytic and cholinergic enzymes in hyperglycemia‐induced testicular injury in type 2 diabetic rats, J. Food Biochem., 43, 10.1111/jfbc.12764 Maritim, 2003, Diabetes, oxidative stress, and antioxidants: a review, J. Biochem. Mol. Toxicol., 17, 24, 10.1002/jbt.10058 I.D.F, 2016 I.D.F, 2018 Rato, 2015, Testicular metabolic reprogramming in neonatal streptozotocin-induced type 2 diabetic rats impairs glycolytic flux and promotes glycogen synthesis, J. Diabetes Res., 2015, 10.1155/2015/973142 Villarroel‐Espíndola, 2013, Muscle glycogen synthase isoform is responsible for testicular glycogen synthesis: glycogen overproduction induces apoptosis in male germ cells, J. Cell. Biochem., 114, 1653, 10.1002/jcb.24507 Yakubu, 2008, Effects of oral administration of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem on some testicular function indices of male rats, J. Ethnopharmacol., 115, 288, 10.1016/j.jep.2007.10.004 Rato, 2013, High‐energy diets may induce a pre‐diabetic state altering testicular glycolytic metabolic profile and male reproductive parameters, Andrology, 1, 495, 10.1111/j.2047-2927.2013.00071.x Gorodeski, 2015, Purinergic signalling in the reproductive system, Auton. Neurosci., 191, 82, 10.1016/j.autneu.2015.04.008 Ayala, 2014, Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal, Oxid. Med. Cell. Longev., 2014, 10.1155/2014/360438 Bener, 2009, Is male fertility associated with type 2 diabetes mellitus?, Int. Urol Nephrol., 41, 777, 10.1007/s11255-009-9565-6 Vinayagam, 2016, Antidiabetic effects of simple phenolic acids: a comprehensive review, Phytother. Res., 30, 184, 10.1002/ptr.5528 Shagirtha, 2011, Hesperetin, a citrus flavonone, protects potentially cadmium induced oxidative testicular dysfunction in rats, Ecotoxicol. Environ. Saf., 74, 2105, 10.1016/j.ecoenv.2011.06.002 Erukainure, 2018, Clerodendrum volubile: phenolics and applications to health Soobrattee, 2005, Phenolics as potential antioxidant therapeutic agents: mechanism and actions, Mutat. Res.-Fund. Mol. M., 579, 200, 10.1016/j.mrfmmm.2005.03.023 Salau, 2020, Vanillin and vanillic acid modulate antioxidant defense system via amelioration of metabolic complications linked to Fe 2+-induced brain tissues damage, Metab. Brain Dis., 35, 727, 10.1007/s11011-020-00545-y Kumar, 2012, A review on the vanillin derivatives showing various biological activities, Int. J. Pharmtech Res., 4, 266 Liang, 2009, Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-κB signaling pathway in human hepatocellular carcinoma cells, Mol. Pharmacol., 75, 151, 10.1124/mol.108.049502 Lirdprapamongkol, 2009, Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo, J. Agric. Food Chem., 57, 3055, 10.1021/jf803366f Iannuzzi, 2017, Vanillin affects amyloid aggregation and non-enzymatic glycation in human insulin, Sci. Rep., 7, 1, 10.1038/s41598-017-15503-5 Lu, 2019, Protective effect of vanillin in streptozotocin-induced diabetes in neonatal rats via attenuation of oxidative stress and inflammation, Trop. J. Pharm. Res., 18, 349, 10.4314/tjpr.v18i2.18 Shaughnessy, 2006, Inhibition of spontaneous mutagenesis by vanillin and cinnamaldehyde in Escherichia coli: dependence on recombinational repair, Mutat. Res-Fund Mol. M., 602, 54, 10.1016/j.mrfmmm.2006.08.006 Zhang, 2004, Anti‐sickling effect of MX‐1520, a prodrug of vanillin: an in vivo study using rodents, Br. J. Hematol., 125, 788, 10.1111/j.1365-2141.2004.04892.x Wilson, 2012, Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes, Pharmacol. Rep., 64, 129, 10.1016/S1734-1140(12)70739-9 Ho, 2011, Toxicology study of vanillin on rats via oral and intra-peritoneal administration, Food Chem. Toxicol., 49, 25, 10.1016/j.fct.2010.08.023 Rahman, 2006, Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method, Nat. Protoc., 1, 3159, 10.1038/nprot.2006.378 Orta-Zavalza, 2014, Catalase activity assay in Candida glabrata, Bio-Protocol, 4, e1072, 10.21769/BioProtoc.1072 Kakkar, 1984, A modified spectrophotometric assay of superoxide dismutase, Indian J. Biochem. Biophys., 21, 130 Chowdhury, 2002, Lipid peroxidation in rat brain is increased by simulated weightlessness and decreased by a soy-protein diet, Ann. Clin. Lab. Sci., 32, 188 Erukainure, 2019, Vernonia Amygdalina Del. stimulated glucose uptake in brain tissues enhances antioxidative activities; and modulates functional chemistry and dysregulated metabolic pathways, Metab. Brain Dis., 34, 721, 10.1007/s11011-018-0363-7 Erukainure, 2021, Cannabis sativa L. mitigates oxidative stress and cholinergic dysfunction; and modulates carbohydrate metabolic perturbation in oxidative testicular injury, Comp. Clin. Pathol., 1 Adewoye, 2000, Ca++, Mg++-ATPase activity in insulin-dependent and non-insulin dependent diabetic Nigerians, Afr. J. Med. Med. Sci., 29, 195 Erukainure, 2017, Dacryodes edulis enhances antioxidant activities, suppresses DNA fragmentation in oxidative pancreatic and hepatic injuries; and inhibits carbohydrate digestive enzymes linked to type 2 diabetes, Biomed. Pharmacother., 96, 37, 10.1016/j.biopha.2017.09.106 Akomolafe, 2017, Effect of caffeine, caffeic acid and their various combinations on enzymes of cholinergic, monoaminergic and purinergic systems critical to neurodegeneration in rat brain—in vitro, NeuroToxicology, 62, 6, 10.1016/j.neuro.2017.04.008 Doleski, 2017, Diphenyl diselenide modulates nucleotidases, reducing inflammatory responses in the liver of Toxoplasma gondii-infected mice, Purinergic Signal., 13, 489, 10.1007/s11302-017-9575-2 Balogun, 2017, Aqueous root extracts of Dicoma anomala (Sond.) extenuates postprandial hyperglycaemia in vitro and its modulation on the activities of carbohydrate-metabolizing enzymes in streptozotocin-induced diabetic Wistar rats, S. Afr. J. Bot., 112, 102, 10.1016/j.sajb.2017.05.014 Salau, 2020, Caffeic acid protects against iron-induced cardiotoxicity by suppressing angiotensin-converting enzyme activity and modulating lipid spectrum, gluconeogenesis and nucleotide hydrolyzing enzyme activities, Biol. Trace Elem. Res., 199, 1052, 10.1007/s12011-020-02227-3 Mahato, 2011, Design, synthesis and glucose-6-phosphatase inhibitory activity of diaminoguanidine analogues of 3-guanidinopropionic acid and amino substituted (pyridin-2-Yl) thiourea derivatives, J. Pharm. Sci. Res., 3, 896 Oboh, 2017, Inhibition of enzymes linked to type-2 diabetes and hypertension by essential oils from peels of orange and lemon, Int. J. Food Prop, 20, S586, 10.1080/10942912.2017.1303709 Erukainure, 2019, Raffia palm (Raphia hookeri G. Mann & H. Wendl) wine modulates glucose homeostasis by enhancing insulin secretion and inhibiting redox imbalance in a rat model of diabetes induced by high fructose diet and streptozotocin, J. Ethnopharmacol., 237, 159, 10.1016/j.jep.2019.03.039 Oyebode, 2020, Crassocephalum rubens (Juss. Ex Jacq.) S. Moore improves pancreatic histology, insulin secretion, liver and kidney functions and ameliorates oxidative stress in fructose-streptozotocin induced type 2 diabetic rats, Drug Chem. Toxicol., 1 Kim, 2010, Anti-obesity effect of Morus bombycis root extract: anti-lipase activity and lipolytic effect, J. Ethnopharmacol., 130, 621, 10.1016/j.jep.2010.05.053 Salau, 2020, Umbelliferone stimulates glucose uptake; modulates gluconeogenic and nucleotide-hydrolyzing enzymes activities, and dysregulated lipid metabolic pathways in isolated psoas muscle, J. Funct. Foods, 67, 10.1016/j.jff.2020.103847 Tsukada, 2010, Structure-based drug design of tricyclic 8H-indeno [1, 2-d][1, 3] thiazoles as potent FBPase inhibitors, Bioorganic Med. Chem. Lett., 20, 1004, 10.1016/j.bmcl.2009.12.056 Thomson, 2009, Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy, Bioorganic Med. Chem. Lett., 19, 1177, 10.1016/j.bmcl.2008.12.085 Trott, 2010, AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading, J. Comput. Chem., 31, 455, 10.1002/jcc.21334 Tian, 2018, CASTp 3.0: computed atlas of surface topography of proteins, Nucleic Acids Res., R46, W363, 10.1093/nar/gky473 Systèmes, 2016 Giri, 2018, Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other pathophysiological consequences: an update on glucose toxicity, Biomed. Pharmacother., 107, 306, 10.1016/j.biopha.2018.07.157 Barkabi-Zanjani, 2020, Diabetes mellitus and the impairment of male reproductive function: possible signaling pathways, Diabetes Metab. Syndr: Clin. Res. Rev., 14, 1307, 10.1016/j.dsx.2020.07.031 Salau, 2020, Phenolics: therapeutic applications against oxidative injury in obesity and type 2 diabetes pathology, 297 Naziroğlu, 2003, Enhanced testicular antioxidant capacity in streptozotocin-induced diabetic rats, Biol. Trace Elem. Res., 94, 61, 10.1385/BTER:94:1:61 Alsenosy, 2019, Graviola (Annona muricata) attenuates behavioural alterations and testicular oxidative stress induced by streptozotocin in diabetic rats, PLoS One, 14, 10.1371/journal.pone.0222410 Soliman, 2019, Olive leaves extract attenuates type II diabetes mellitus-induced testicular damage in rats: molecular and biochemical study, Saudi Pharm. J., 27, 326, 10.1016/j.jsps.2018.11.015 Mruk, 2002, Antioxidant superoxide dismutase-a review: its function, regulation in the testis, and role in male fertility⋆, Contraception, 65, 305, 10.1016/S0010-7824(01)00320-1 Aitken, 2008, Antioxidant systems and oxidative stress in the testes, Oxid. Med. Cell. Longev., 1, 15, 10.4161/oxim.1.1.6843 Agarwal, 2005, Oxidative stress and antioxidants in male infertility: a difficult balance, Iran. J. Reprod. Med., 3, 1 Abreu, 2010, Superoxide dismutases—a review of the metal-associated mechanistic variations, Biochim. Biophys. Acta-Proteins Proteom., 1804, 263, 10.1016/j.bbapap.2009.11.005 Doshi, 2012, Role of reactive nitrogen species in male infertility, Reprod. Biol. Endocrinol., 10, 109, 10.1186/1477-7827-10-109 Uribe, 2014, Peroxynitrite-mediated nitrosative stress decreases motility and mitochondrial membrane potential in human spermatozoa, MHR: Basic Sci. Reprod. Med., 21, 237 Schirmer, 2011, The cholinergic system in rat testis is of non-neuronal origin, Reproduction, 10.1530/REP-10-0302 Bray, 2005, Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility, Biol. Reprod., 73, 807, 10.1095/biolreprod.105.042184 Gómez, 2009, Expression and regulation of insulin and the glucose transporter GLUT8 in the testes of diabetic rats, Horm. Metab. Res., 41, 343, 10.1055/s-0028-1128146 Rato, 2012, Metabolic regulation is important for spermatogenesis, Nat. Rev. Urol., 9, 330, 10.1038/nrurol.2012.77 Alves, 2013, Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function, Tissue Barriers, 1, e23992, 10.4161/tisb.23992 Shi, 2018, Characterization of cholesterol metabolism in Sertoli cells and spermatogenesis, Mol. Med. Rep., 17, 705 Pushpendra, 2015, Hyper-lipidemia and male fertility: a critical review of literature, Andrology, 4