Value of ileus-prophylactic surgery for metastatic neuroendocrine midgut tumours

Abou Saleh, 2019, Prevalence of small intestine carcinoid tumors: a US population-based study 2012-2017, Dig Dis Sci, 64, 1328, 10.1007/s10620-018-5402-z Niederle, 2016, ENETS consensus guidelines update for neuroendocrine neoplasms of the jejunum and ileum, Neuroendocrinology, 103, 125, 10.1159/000443170 Dasari, 2017, Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States, JAMA Oncol, 3, 1335, 10.1001/jamaoncol.2017.0589 Anlauf, 2014, Neuroendocrine neoplasms of the distal jejunum and ileum, Pathologe, 35, 283, 10.1007/s00292-013-1888-5 Pasquer, 2015, Surgical management of small bowel neuroendocrine tumors: specific requirements and their impact on staging and prognosis, Ann Surg Oncol, 22, S742, 10.1245/s10434-015-4620-2 Blazevic, 2018, Small intestinal neuroendocrine tumours and fibrosis: an entangled conundrum, Endocr Relat Cancer, 25, R115, 10.1530/ERC-17-0380 Watzka, 2016, Surgical treatment of NEN of small bowel: a retrospective analysis, World J Surg, 40, 749, 10.1007/s00268-016-3432-2 Weber, 2018, Surgical aspects of neuroendocrine tumors of the small intestine, Chirurg, 89, 428, 10.1007/s00104-018-0607-4 Walsh, 2016, Ileal "carcinoid" tumors-small size belies deadly intent: high rate of nodal metastasis in tumors </=1 cm in size, Hum Pathol, 56, 123, 10.1016/j.humpath.2016.05.023 Wu, 2017, Survival outcomes and surgical intervention of small intestinal neuroendocrine tumors: a population based retrospective study, Oncotarget, 8, 4935, 10.18632/oncotarget.13632 Howe, 2017, The surgical management of small bowel neuroendocrine tumors: consensus guidelines of the North American neuroendocrine tumor society, Pancreas, 46, 715, 10.1097/MPA.0000000000000846 Lardiere-Deguelte, 2016, Toward a preoperative classification of lymph node metastases in patients with small intestinal neuroendocrine tumors in the era of intestinal-sparing surgery, Neuroendocrinology, 103, 552, 10.1159/000441423 Pasquer, 2016, Lymphadenectomy during small bowel neuroendocrine tumor surgery: the concept of skip metastases, Ann Surg Oncol, 23, 804, 10.1245/s10434-016-5574-8 Choi, 2017, Is multifocality an indicator of aggressive behavior in small bowel neuroendocrine tumors?, Pancreas, 46, 1115, 10.1097/MPA.0000000000000911 Ethun, 2016, Small bowel neuroendocrine tumors: a critical analysis of diagnostic work-up and operative approach, J Surg Oncol, 114, 671, 10.1002/jso.24390 Clift, 2016, Role of staging in patients with small intestinal neuroendocrine tumours, J Gastrointest Surg, 20, 180, 10.1007/s11605-015-2953-6 Norlen, 2010, Prophylactic cholecystectomy in midgut carcinoid patients, World J Surg, 34, 1361, 10.1007/s00268-010-0428-1 Sinnamon, 2018, Prophylactic cholecystectomy at time of surgery for small bowel neuroendocrine tumor does not increase Postoperative Morbidity, Ann Surg Oncol, 25, 239, 10.1245/s10434-017-6093-y Trendle, 1997, Incidence and morbidity of cholelithiasis in patients receiving chronic octreotide for metastatic carcinoid and malignant islet cell tumors, Cancer, 79, 830, 10.1002/(SICI)1097-0142(19970215)79:4<830::AID-CNCR20>3.0.CO;2-# Kim, 2015, Prognostic significance of lymph node metastases in small intestinal neuroendocrine tumors, Neuroendocrinology, 101, 58, 10.1159/000371807 Landry, 2013, Resection of at-risk mesenteric lymph nodes is associated with improved survival in patients with small bowel neuroendocrine tumors, World J Surg, 37, 1695, 10.1007/s00268-013-1918-8 Akerström, 2001, Midgut and hindgut carcinoid tumors, 447 Fata, 2017, Mesenteric tumor deposits in midgut small intestinal neuroendocrine tumors are a stronger indicator than lymph node metastasis for liver metastasis and poor prognosis, Am J Surg Pathol, 41, 128, 10.1097/PAS.0000000000000751 Blazevic, 2018, Mesenteric fibrosis and palliative surgery in small intestinal neuroendocrine tumours, Endocr Relat Cancer, 25, 245, 10.1530/ERC-17-0282 Gonzalez, 2014, Should mesenteric tumor deposits be included in staging of well-differentiated small intestine neuroendocrine tumors?, Mod Pathol, 27, 1288, 10.1038/modpathol.2013.232 Malik, 2019, Impact of mesenteric mass in patients with midgut neuroendocrine tumors, Pancreas, 48, 682, 10.1097/MPA.0000000000001309 Tsilimigras, 2019, Is resection of primary midgut neuroendocrine tumors in patients with unresectable metastatic liver disease justified? A systematic review and meta-analysis, J Gastrointest Surg, 23, 1044, 10.1007/s11605-018-04094-9 Guo, 2017, Systematic review of resecting primary tumor in MNETs patients with unresectable liver metastases, Oncotarget, 8, 17396, 10.18632/oncotarget.14156 Givi, 2006, Operative resection of primary carcinoid neoplasms in patients with liver metastases yields significantly better survival, Surgery, 140, 891, 10.1016/j.surg.2006.07.033 Norlen, 2012, Long-term results of surgery for small intestinal neuroendocrine tumors at a tertiary referral center, World J Surg, 36, 1419, 10.1007/s00268-011-1296-z Tierney, 2019, Resection of primary tumor may prolong survival in metastatic gastroenteropancreatic neuroendocrine tumors, Surgery, 165, 644, 10.1016/j.surg.2018.09.006 Lewis, 2018, Resection of the primary gastrointestinal neuroendocrine tumor imporves survival with or without liver treatment, Ann Surg Laskaratos, 2018, Evaluation of clinical prognostic factors and further delineation of the effect of mesenteric fibrosis on survival in advanced midgut neuroendocrine tumours, Neuroendocrinology, 107, 292, 10.1159/000493317 Strosberg, 2009, Survival and prognostic factor analysis of 146 metastatic neuroendocrine tumors of the mid-gut, Neuroendocrinology, 89, 471, 10.1159/000197899 Hafeez, 2017, Clinical profile and treatment outcomes of advanced neuroendocrine tumours in rural and regional patients: a retrospective study from a regional cancer centre in North Queensland, Australia, Intern Med J, 47, 284, 10.1111/imj.13333 Hallet, 2015, Rural-urban disparities in incidence and outcomes of neuroendocrine tumors: a population-based analysis of 6271 cases, Cancer, 121, 2214, 10.1002/cncr.29338 Zhou, 2017, Racial disparities in pancreatic neuroendocrine tumors survival: a SEER study, Cancer Med, 6, 2745, 10.1002/cam4.1220 Daskalakis, 2018, Association of a prophylactic surgical approach to stage IV small intestinal neuroendocrine tumors with survival, JAMA Oncol, 4, 183, 10.1001/jamaoncol.2017.3326 National Comprehensive Cancer Network. NCCN guidelines version 3.2017. Neuroendocrine tumors of the gastrointestinal tract, lung and thymus (carcinoid tumors). Available from: URL: https://www.nccn.org/professionals/physician_gls/default.aspx. Woltering, 2017, Aggressive surgical approach to the management of neuroendocrine tumors: a report of 1,000 surgical cytoreductions by a single institution, J Am Coll Surg, 224, 434, 10.1016/j.jamcollsurg.2016.12.032 Wang, 2016, Neuroendocrine tumors (NETs) of unknown primary: is early surgical exploration and aggressive debulking justifiable?, Chin Clin Oncol, 5, 4 Manguso, 2018, Long-term outcomes after elective versus emergency surgery for small bowel neuroendocrine tumors, Am Surg, 84, 1570, 10.1177/000313481808401006 Ahmed, 2009, Midgut neuroendocrine tumours with liver metastases: results of the UKINETS study, Endocr Relat Cancer, 16, 885, 10.1677/ERC-09-0042 Huttner, 2015, Palliative resection of the primary tumor in 442 metastasized neuroendocrine tumors of the pancreas: a population-based, propensity score-matched survival analysis, Langenbeck's Arch Surg, 400, 715, 10.1007/s00423-015-1323-x Bertani, 2016, Resection of the primary tumor followed by peptide receptor radionuclide therapy as upfront strategy for the treatment of G1-G2 pancreatic neuroendocrine tumors with unresectable liver metastases, Ann Surg Oncol, 23, 981, 10.1245/s10434-016-5550-3