Utility of the PHQ-9 to identify major depressive disorder in adult patients in Spanish primary care centres

Cano-Vindel A. Los desórdenes emocionales en Atención Primaria [Emotional disorders in primary care]. Ansiedad y Estrés. 2011;17(1):75–97.

Fernández A, Pinto-Meza A, Bellón JA, et al. Is major depression adequately diagnosed and treated by general practitioners? Results from an epidemiological study. Gen Hosp Psychiatry. 2010;32(2):201–9.

Fernández A, Haro JM, Codony M, et al. Treatment adequacy of anxiety and depressive disorders: primary versus specialised care in Spain. J Affect Disord. 2006;96:9–20.

National Institute for Health and Clinical Excellence (NICE). Common mental health problems: identification and pathways to care. London, UK: National Institute for Health and Clinical Excellence (NICE); 2011.

Parés-Badell O, Barbaglia G, Jerinic P, et al. Cost of disorders of the brain in Spain. PLoS One. 2014;9(8):e105471.

Gili M, Roca M, Basu S, McKee M, Stuckler D. The mental health risks of economic crisis in Spain: evidence from primary care centres, 2006 and 2010. Eur J Pub Health. 2013;23(1):103–8.

Mitchell AJ, Vaze A, Rao S. Clinical diagnosis of depression in primary care: a meta-analysis. Lancet. 2009;374(9690):609–19.

Serrano-Blanco A, Palao DJ, Luciano JV, et al. Prevalence of mental disorders in primary care: results from the diagnosis and treatment of mental disorders in primary care study (DASMAP). Soc Psychiatry Psychiatr Epidemiol. 2010;45(2):201–10.

Cano A, Salguero JM, Wood CM, Dongil E, Latorre JM. La depresión en atención primaria: prevalencia, diagnóstico y tratamiento. Pápeles del Psicólogo. 2012;33(1):2–11.

National Collaborating Centre for Mental Health (UK). Depression: the treatment and management of depression in adults (updated edition). British Psychological Society. 2010.

Malpass A, Dowrick C, Gilbody S, Robinson J, Wiles N, Duffy L, et al. Usefulness of PHQ-9 in primary care to determine meaningful symptoms of low mood: a qualitative study. Br J Gen Pract. 2016;66(643):e78–84.

Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–13.

Williams JW, Pignone M, Ramirez G, Perez SC. Identifying depression in primary care: a literature synthesis of case-finding instruments. Gen Hosp Psychiatry. 2002;24(4):225–37.

Gilbody S, Richards D, Brealey S, Hewitt C. Screening for depression in medical settings with the patient health questionnaire (PHQ): a diagnostic meta-analysis. J Gen Intern Med. 2007;22(11):1596–602.

Manea L, Gilbody S, McMillan D. Optimal cut-off score for diagnosing depression with the Patient Health Questionnaire (PHQ-9): A meta-analysis. CMAJ. 2012;184(3):E191-6.

Pinto-Meza A, Serrano-Blanco A, Peñarrubia MT, Blanco E, Haro JM. Assessing depression in primary care with the PHQ-9: can it be carried out over the telephone? J Gen Intern Med. 2005;20(8):738–42.

de Lima OF, Vilela Mendes A, Crippa JA, Loureiro SR. Study of the discriminative validity of the phq-9 and phq-2 in a sample of Brazilian women in the context of primary health care. Perspect Psychiatr Care. 2009;45(3):216–27.

Chen I-P, Liu S-I, Huang H-C, et al. Validation of the Patient Health Questionnaire for Depression Screening Among the Elderly Patients in Taiwan. Int J Gerontol. 2016;10(4):193–7.

Gelaye B, Williams MA, Lemma S, et al. Validity of the patient health questionnaire-9 for depression screening and diagnosis in east Africa. Psychiatry Res. 2013;210(2):653–61.

Phelan E, Williams B, Meeker K, et al. A study of the diagnostic accuracy of the PHQ-9 in primary care elderly. BMC Fam Pract. 2010;11:63.

Cholera R, Gaynes BN, Pence BW, et al. Validity of the patient health questionnaire-9 to screen for depression in a high-HIV burden primary healthcare clinic in Johannesburg, South Africa. J Affect Disord. 2014;167:160–6.

Löwe B, Kroenke K, Herzog W, Gräfe K. Measuring depression outcome with a brief self-report instrument: sensitivity to change of the patient health questionnaire (PHQ-9). J Affect Disord. 2004;81(1):61–6.

Kroenke K, Spitzer RL, Williams JBW, Löwe B. The patient health questionnaire somatic, anxiety, and depressive symptom scales: a systematic review. Gen Hosp Psychiatry. 2010;32(4):345–59.

Manea L, Gilbody S, McMillan D. A diagnostic meta-analysis of the patient health questionnaire-9 (PHQ-9) algorithm scoring method as a screen for depression. Gen Hosp Psychiatry. 2015;37(1):67–75.

Mitchell AJ, Yadegarfar M, Gill J, Stubbs B. Case finding and screening clinical utility of the patient health questionnaire (PHQ-9 and PHQ-2) for depression in primary care: a diagnostic meta-analysis of 40 studies. British Journal of Psychiatry Open. 2016;2(2):127–38.

Diez-Quevedo C, Rangil T, Sanchez-Planell L, Kroenke K, Spitzer RL. Validation and utility of the patient health questionnaire in diagnosing mental disorders in 1003 general hospital Spanish inpatients. Psychosom Med. 2001;63(4):679–86.

Wulsin L, Somoza E, Heck J. The feasibility of using the Spanish PHQ-9 to screen for depression in primary Care in Honduras. Prim Care Companion J Clin Psychiatry. 2002;4(5):191–5.

Cano-Vindel A, Muñoz-Navarro R, Wood CM, et al. Transdiagnostic cognitive behavioral therapy versus treatment as usual in adult patients with emotional disorders in the primary care setting (PsicAP study): protocol for a randomized controlled trial. JMIR Res Protoc. 2016;5(4):e246.

Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary care evaluation of mental disorders. Patient health questionnaire. JAMA. 1999;282(18):1737–44.

García-Campayo J, Zamorano E, Ruiz MA, et al. Cultural adaptation into Spanish of the generalized anxiety disorder-7 (GAD-7) scale as a screening tool. Health Qual Life Outcomes. 2010;8(1):8.

First M, Spitzer R, Gibbon M, Williams J. Entrevista clínica estructurada para los trastornos del eje I del DSM-IV: SCID-I. Barcelona, Spain, Masson; 1999.

Robin X, Turck N, Hainard A, et al. pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinformatics. 2011;12(1):77.

R Development Core Team R. R: A Language and Environment for Statistical Computing. Vol 1.; 2011.

Youden WJ. Index for rating diagnostic tests. Cancer. 1950;3(1):32–5.

Muñoz-Navarro R, Cano-Vindel A, Wood CM, et al. The PHQ-PD as a screening tool for panic disorder in the primary care setting in Spain. PLoS One. 2016;11(8):e0161145.

Wittkampf K, van Ravesteijn H, Baas K, et al. The accuracy of patient health questionnaire-9 in detecting depression and measuring depression severity in high-risk groups in primary care. Gen Hosp Psychiatry. 2009;31(5):451–9.

Zimmerman M, Martinez JH, Friedman M, Boerescu DA, Attiullah N, Toba C. How can we use depression severity to guide treatment selection when measures of depression categorize patients differently? J Clin Psychiatry. 2012;73(10):1287–91.

Brown TA, Barlow DH. A proposal for a dimensional classification system based on the shared features of the DSM-IV anxiety and mood disorders: implications for assessment and treatment. Psychol Assess. 2009;21(3):256.