Using MTBindingSim as a Tool for Experimental Planning and Interpretation

Ackmann, 2000, Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation, Journal of Biological Chemistry, 275, 30335, 10.1074/jbc.M002590200 Akhmanova, 2008, Tracking the ends: A dynamic protein network controls the fate of microtubule tips, Nature Reviews. Molecular Cell Biology, 9, 309, 10.1038/nrm2369 Alberico, 2013, Biochemical evidence that human EB1 does not bind preferentially to the microtubule seam, Cytoskeleton, 70, 317, 10.1002/cm.21108 Amos, 2005, Microtubules and maps, Advances in Protein Chemistry, 71, 257, 10.1016/S0065-3233(04)71007-4 Desai, 1997, Microtubule polymerization dynamics, Annual Review of Cell and Developmental Biology, 13, 83, 10.1146/annurev.cellbio.13.1.83 Duan, 2012, Taxol-stabilized microtubules promote the formation of filaments from unmodified full-length tau in vitro, Molecular Biology of the Cell, 23, 4796, 10.1091/mbc.E12-05-0374 Goode, 1994, Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau, The Journal of Cell Biology, 124, 769, 10.1083/jcb.124.5.769 Gupta, 2010, Probing interactions between CLIP-170, EB1, and microtubules, Journal of Molecular Biology, 395, 1049, 10.1016/j.jmb.2009.11.014 Gupta, 2009, Minimal plus-end tracking unit of the cytoplasmic linker protein CLIP-170, Journal of Biological Chemistry, 284, 6735, 10.1074/jbc.M807675200 Gustke, 1994, Domains of tau protein and interactions with microtubules, Biochemistry, 33, 9511, 10.1021/bi00198a017 Howard, 2003, Dynamics and mechanics of the microtubule plus end, Nature, 422, 753, 10.1038/nature01600 Kar, 2003, Repeat motifs of tau bind to the insides of microtubules in the absence of taxol, EMBO Journal, 22, 70, 10.1093/emboj/cdg001 Lansbergen, 2006, Microtubule plus end: A hub of cellular activities, Traffic, 7, 499, 10.1111/j.1600-0854.2006.00400.x Makrides, 2004, Evidence for two distinct binding sites for tau on microtubules, Proceedings of the National Academy of Sciences of the United States of America, 101, 6746, 10.1073/pnas.0400992101 Makrides, 2003, Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies, The Journal of Biological Chemistry, 278, 33298, 10.1074/jbc.M305207200 Maurer, 2012, EBs recognize a nucleotide-dependent structural cap at growing microtubule ends, Cell, 149, 371, 10.1016/j.cell.2012.02.049 Philip, 2012, MTBindingSim: Simulate protein binding to microtubules, Bioinformatics (Oxford, England), 28, 441, 10.1093/bioinformatics/btr684 Sandblad, 2006, The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam, Cell, 127, 1415, 10.1016/j.cell.2006.11.025 Zhu, 2009, Interactions between EB1 and microtubules: Dramatic effect of affinity tags and evidence for cooperative behavior, Journal of Biological Chemistry, 284, 32651, 10.1074/jbc.M109.013466