Use of the sleep clinical record in the follow-up of children with obstructive sleep apnea (OSA) after treatment

Sleep and Breathing - Tập 20 - Trang 321-329 - 2015
Maria Pia Villa1, Anna Sujanska2, Ottavio Vitelli1, Melania Evangelisti1, Jole Rabasco1, Nicoletta Pietropaoli1, Peter Banovcin2, Leila Kheirandish-Gozal3, David Gozal3
1Neuroscience, Mental Health and Sense Organs Department, Pediatric Sleep Disease Centre, S. Andrea Hospital, Sapienza University of Rome, Rome, Italy
2Department of Pediatrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia
3Section of Sleep Medicine, Department of Pediatrics, Comer Children’s Hospital, Pritzker School of Medicine, Biological Sciences Division, The University of Chicago, Chicago, USA

Tóm tắt

The aim of our study was to evaluate the utility of the sleep clinical record (SCR) in the follow-up of children with obstructive sleep apnea (OSA) after treatment. SCR was completed and overnight polysomnography (PSG) was performed in all enrolled children (T0), with SCR considered positive for scores ≥6.5, as previously validated. Patients underwent adenotonsillectomy (T&A), rapid maxillary expansion (RME), and medical therapy according to severity of OSA and clinical features. Six months after completing therapy, the second overnight PSG and SCR (T1) were performed. For all subjects, both Apnea-Hypopnea Index (AHI) and total SCR score decreased significantly (<0.005) from T0 to T1. For SCR items, clinical examination (item 1) and reported sleep respiratory symptoms (item 2) ameliorated significantly (<0.005). However, hyperactivity or inattention (item 3) decreased significantly (<0.005) after treatment only in T&A group, while no differences in AHI and SCR scores occurred in the medically treated group. At T1, SCR was positive in 95.6 % of children with AHI ≥1, with a concordance of 100 % in the T&A and RME groups, resulting in a positive predictive value of 100 %. A poor concordance (38.3 % in T&A group and 53.4 % in RME group) was found when SCR < 6.5. Children with SCR ≥ 6.5 at T1 showed higher AHI compared to patients with SCR < 6.5 (5.7 ± 5.9 ev/h vs 1.78 ± 1.76 ev/h; p < 0.005). SCR emerges as a potentially useful instrument for follow-up of children with OSA after treatment.

Tài liệu tham khảo

Tauman R, Gozal D (2011) Obstructive sleep apnea syndrome in children. Expert Rev Respir Med 3:425–440 Marcus SL, Brooks LJ, Draper KA et al (2012) Diagnosis and management of childhood obstructive sleep apnea syndrome. Clinical practise guideline. Pediatrics 130:576–584 De Almeida LA, Anselmo-Lima WT, Valera FCP (2011) OSAS in children: where are we? Braz J Otorhinolaryngol 77(3):273 Hoban TF (2005) Obstructive sleep apnea. Curr Sci Options Neurol 7:353–361 Powell S, Kubba H, Brien C, Tremlett M (2010) Paediatric obstructive sleep apnoea. BMJ 340:1018–1023 Bhattacharjee R, Kim J, Kheirandish-Gozal L, Gozal D (2011) Obesity and obstructive sleep apnea syndrome in children: a tale of inflammatory cascades. Pediatr Pulmonol 46:313–323 Gozal D, Kheirandish-Gozal L, Bhattacharjee R, Kim J (2012) C-reactive protein and obstructive sleep apnea syndrome in children. Front Biosci (Elite Ed) 1(4):2410–2422 Gozal D, Capdevila OS, Kheirandish-Gozal L (2008) Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children. Am J Respir Crit Care Med 177:1142–1149 Chervin RD, Dillon JE, Bassetti C, Ganoczy DA, Pituch KJ (1997) Symptoms of sleep disorders, inattention, and hyperactivity in children. Sleep 20:1185–1192 Carroll JL, McColley SA, Marcus CL et al (1995) Inability of clinical history to distinguish primary snoring from obstructive sleep apnea syndrome in children. Chest 108:610–618 Xu Z, Cheuk DK, Lee SL (2006) Clinical evaluation in predicting childhood obstructive sleep apnea. Chest 130:1765–1771 Chervin RD, Hedger K, Dillon JE et al (2000) Pediatric sleep questionnaire (PSQ): validity and reliability of scales for sleep-disordered breathing, snoring, sleepiness, and behavioural problems. Sleep Med 1:21–32 Villa MP, Paolino MC, Castaldo R et al (2013) Sleep clinical record: an aid to rapid and accurate diagnosis of pediatric sleep disordered breathing. Eur Respir J 41:1355–1361 Arens R, McDonough JM, Costarino AT et al (2001) Magnetic resonance imaging of the upper airway structure of children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 164:698–703 Marcus CL, Moore RH, Rosen CL, Giordani B, Garetz SL, Taylor HG, Mitchell RB, Amin R, Katz ES, Arens R, Paruthi S, Muzumdar H, Gozal D, Thomas NH, Ware J, Beebe D, Snyder K, Elden L, Sprecher RC, Willging P, Jones D, Bent JP, Hoban T, Chervin RD, Ellenberg SS, Redline S (2013) Childhood Adenotonsillectomy Trial (CHAT). A randomized trial of adenotonsillectomy for childhood sleep apnea. N Engl J Med 368(25):2366–2376 Iber C, Ancoli-Israel S, Chesson A, et al. (2007) The AASM manual for the scoring of sleep and associated event: rules, terminology and technical specifications. 1 st ed. Am Acad Sleep Med Berry RB, Budhiraja R, Gottlieb DJ et al (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 8:597–619 Liistro G, Rombaux P, Belge C, Dury M, Aubert G, Rodenstein DO (2003) High Mallampati score and nasal obstruction are associated risk factors for obstructive sleep apnoea. Eur Respir J 21(2):248–252 Friedman M, Ibrahim H, Joseph NJ (2004) Staging of obstructive sleep apnea/hypopnea syndrome: a guide to appropriate treatment. Laryngoscope 114:454–459 Angle EH (1907) Treatment of malocclusion of the teeth: Angle’s system. SS White Dental Manufacturing Co., Philadelphia Arens R, Marcus CL (2004) Pathophysiology of upper airway obstruction: a developmental perspective. Sleep 27:997–1019 Brouilette R, Hanson D, David R et al (1984) A diagnostic approach to suspected obstructive sleep apnea in children. J Pediatr 105:10–14 DuPaul GJ, McGoey KE, Eckert TL, VanBrakle J (2001) Preschool children with attention-deficit/hyperactivity disorder: impairments in behavioral, social and school functioning. J Am Acad Child Adolesc Psychiatry 40:508–515 Ye J, Liu H, Zhang GH, Li P, Yang QT, Liu X, Li Y (2010) Outcome of adenotonsillectomy for obstructive sleep apnea syndrome in children. Ann Otol Rhinol Laryngol 119:506–513 Villa MP, Brasili L, Ferretti A, Vitelli O et al (2015) Oropharyngeal exercises to reduces symptoms of OSA after AT. Sleep Breath 19(1):281–289 Villa MP, Castaldo R, Miano S et al (2013) Adenotonsillectomy and orthodontic therapy in paediatric obstructive sleep apnea. Sleep Breath 18(3):533–539, 2014 Sep Katz ES, Moore RH, Rosen CL et al (2014) Growth after adenotonsillectomy for obstructive sleep apnea: an RCT. Pediatrics 134:282–289 Amin R, Anthony L, Somers V et al (2008) Growth velocity predicts recurrence of sleep-disordered breathing 1 year after adenotonsillectomy. Am J Respir Crit Care Med 177:654–659 Ayral M, Baylan MY, Kinis V et al (2013) Evaluation of hyperactivity, attention deficit, and impulsivity before and after adenoidectomy/adenotonsillectomy surgery. J Craniofac Surg 24:731–734