Use of gold nanoparticles for immobilization of L-cysteine on TLC plates

Moscow University Chemistry Bulletin - Tập 64 - Trang 159-164 - 2009
E. N. Shapovalova1, I. A. Ananieva1, A. G. Majouga1, N. V. Zik2, O. A. Shpigun1
1Chair of Analytical Chemistry, Chemical Faculty, Moscow State University, Moscow, Russia
2Chair of Organic Chemistry, Chemical Faculty, Moscow State University, Moscow, Russia

Tóm tắt

A new method of immobilization of the chiral selector on the surface of TLC plates by means of stepwise impregnation by gold nanoparticles and L-cysteine is described. The novel silica- and alumina-based stationary phases for TLC demonstrate enantioselectivity toward tetrahydrozoline, hydroxyzine, ketoprofen, fenoprofen, pindolol, and fluoxetine. The influence of the composition of the mobile phase on the R f values and enantioselectivity is also discussed.

Tài liệu tham khảo

Bhushan, R., Martens, J. Biomed. Chromatogr., 1996, vol. 11, p. 280. Bhushan, R., Ali, I., Chromatographia, 1993, vol. 35, p. 679. Gunter, K., J. Chromatogr., 1988, vol. 448, p. 11. Reich, S., Eike, B., Schibli, P., and Anne, D., Biomed. Chromatogr., 2005, vol. 23, p. 458. Daniel, M.-Ch., and Didier, A.A., Chem. Rev., 2004, vol. 104, p. 293. Brust, M., Walker, M., Bethell, D., Schifrin, D.J., and Whyman, R.J., J. Chem. Soc., Chem. Commun., 1994, p. 801. Ding, Sh.-J., Chemg, B.-W., Wu, Ch.-Ch., Lai, M.-F., and Chang, H.-Ch., Anal. Chim. Acta, 2005, vol. 554, p. 43. Chem, D., and Li, J., Surf. Sci. Rep., 2006, vol. 61, p. 445.