Urokinase Plasminogen Activator Induces Angiogenesis and Tumor Vessel Invasion in Breast Cancer

Pathology - Research and Practice - Tập 191 - Trang 403-409 - 1995
R. Hildenbrand1, I. Dilger1, A. Hörlin1, H.J. Stutte1
1Senckenbergisches Zentrum der Pathologie, Klinikum der J. W. GoetheUniversität, Frankfurt, FRG

Tài liệu tham khảo

Blasi, 1988, Surface receptors for urokinase plasminogen activator, Fibrinolyses, 2, 158 Burgdorf, 1981, Immunohistochemical identification of Factor VIII-related antigen in endothelial cells of cutaneous lesions of alleged vascular nature, Am J Clin Pathol, 7S, 167, 10.1093/ajcp/75.2.167 Camiolo, 1987, Plasminogen activator content of gynecological tumors and their metastases, Gynecol Oncol, 26, 364, 10.1016/0090-8258(87)90028-X Cordell, 1984, Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal antialkaline phosphatase (APAAP complexes), J Histochem Cytochem, 32, 219, 10.1177/32.2.6198355 Dano, 1985, Plasminogen activators, tissue degradation and cancer, Adv Cancer Res, 44, 139, 10.1016/S0065-230X(08)60028-7 Duffy, 1990, Urokinase plasminogen activator, a new and independent prognostic marker in breast cancer, Cancer Res, 50, 6827 Foekens, 1992, Prognostic value of urokinase type plasminogen activator in 671 primary breast cancer patients, Cancer Res, 52, 6101 Gelehrter, 1983, Plasminogen activator inhibitors and hormonal regulation in rat hepatoma cell line HTC, B J Mol Cell Biochem, 53/54, 11 Goretzki, 1992, Effective activation of the proenzyme form of the urokinase type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L, FEBS-Letters, 297, 112, 10.1016/0014-5793(92)80339-I Horak, 1992, Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies as indicator of node metastases and survival in breast cancer, Lancet, 340, 1120, 10.1016/0140-6736(92)93150-L Jänicke, 1990, Urokinase-type plasminogen activator (uPA) antigen is a predictor of early relapse in breast cancer, Fibrinolysis, 4, 69, 10.1016/0268-9499(90)90001-Z Jänicke, 1993, Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node negative breast cancer, Breast Cancer Res and Treat, 24, 195, 10.1007/BF01833260 Jänicke, 1989, Urokinase-type plasminogen activator antigen and early relapse in breast cancer, The Lancet, 2, 1049, 10.1016/S0140-6736(89)91070-2 Le Doussal, 1989, Prognostic value of histologic grade nuclear components of Scarff-Bloom-Richardson (SBR): an improved score modification based on a multivariate analysis of 1262 invasive ductal breast carcinomas, Cancer, 64, 1914, 10.1002/1097-0142(19891101)64:9<1914::AID-CNCR2820640926>3.0.CO;2-G Mahadevan, 1990, Metastases and angiogenesis, Acta Oncol, 29, 97, 10.3109/02841869009089997 Markus, 1988, The relevance of plasminogen activators to neoplastic growth, Enzyme, 40, 158, 10.1159/000469158 Markus, 1983, Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumors, Cancer Res, 43, 55175525 MC Comb, 1982, Specif ity and sensitivity of immunohistochemical detection of factor VIII/von Willebrand factor antigen in formalin fixed paraffin-embedded tissue, J Histochem Cytochem, 30, 371377 Moscatelli, 1981, Angiogenic factors stimulate plasminogen activator and collagenase production by capillary endothelium cells, J Cell Biol, 91, 201a Nagy, 1989, Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition, Biochim Biophys Acta, 948, 305326 Sato, 1993, Indispensable role of tissue-type plasminogen activator in growth factor-dependent tube formation of human microvascular endothelial cells in vitro, Exp Cell Res, 204, 223229, 10.1006/excr.1993.1028 Schmitt, 1989, Elastase released from human granulocytes stimulated with N-formylchemotactic peptide prevents activation of tumor cell prourokinase, FEBS Lett, 255, 83, 10.1016/0014-5793(89)81065-8 Skriver, 1984, Immunocytochemical localisation of urokinase-type plasminogen activator in Lewis lung carcinoma, J Cell Biol, 99, 753, 10.1083/jcb.99.2.753 Stump, 1986, Purification and characterization of low molecular weight form of single-chain urokinase-type plasminogen activator, J Biol Chem, 261, 17120, 10.1016/S0021-9258(19)76007-4 Thorpe, 1988, Estrogen and progesterone receptor determinations in breast cancer, Technology, biology and clinical significance. Acta Oncol, 27, 1 Yasunaga, 1989, A role of fibrinolytic activity in angiogenesis, Quantitative assay using in vitro method. Lab Invest, 61, 698