Urinary epidermal growth factor in kidney disease: A systematic review

Zeng, 2014, Epidermal growth factor, from gene organization to bedside, Semin Cell Dev Biol, 28, 2, 10.1016/j.semcdb.2014.01.011 Rayego-Mateos, 2018, Role of epidermal growth factor receptor (EGFR) and its ligands in kidney inflammation and damage, Mediat Inflamm, 2018, 8739473, 10.1155/2018/8739473 Swartling, 2021, CKD progression and mortality among men and women: a nationwide study in Sweden, Am J Kidney Dis, 78, 190, 10.1053/j.ajkd.2020.11.026 Stroup, 2000, Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group, JAMA, 283, 2008, 10.1001/jama.283.15.2008 Page, 2021, The PRISMA 2020 statement: an updated guideline for reporting systematic reviews, BMJ, 372, n71, 10.1136/bmj.n71 National Heart, Lung, and Blood Institute; National Institutes of Health; U.S. Department of Health and Human Services. Study Quality Assessment Tools. https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools [accessed 28.8.21]. Gesualdo, 1995, Urinary epidermal growth factor concentration in patients affected by ADPKD, Contrib Nephrol, 115, 105, 10.1159/000424404 Jørgensen, 1995, Urinary excretion of epidermal growth factor in living human kidney donors and their recipients, Eur J Clin Invest, 25, 442, 10.1111/j.1365-2362.1995.tb01727.x Ranieri, 1996, Urinary IL-6/EGF ratio: a useful prognostic marker for the progression of renal damage in IgA nephropathy, Kidney Int, 50, 1990, 10.1038/ki.1996.521 Torffvit, 1998, Urinary excretion of Tamm-Horsfall protein and epidermal growth factor in chronic nephropathy, Nephron, 79, 167, 10.1159/000045020 Torres, 2008, The ratio of epidermal growth factor to monocyte chemotactic peptide-1 in the urine predicts renal prognosis in IgA nephropathy, Kidney Int, 73, 327, 10.1038/sj.ki.5002621 Stangou, 2009, Urinary levels of epidermal growth factor, interleukin-6 and monocyte chemoattractant protein-1 may act as predictor markers of renal function outcome in immunoglobulin A nephropathy, Nephrology (Carlton), 14, 613, 10.1111/j.1440-1797.2008.01051.x Stangou, 2012, Detection of multiple cytokines in the urine of patients with focal necrotizing glomerulonephritis may predict short and long term outcome of renal function, Cytokine, 57, 120, 10.1016/j.cyto.2011.10.003 Harskamp, 2015, Urinary EGF receptor ligand excretion in patients with autosomal dominant polycystic kidney disease and response to tolvaptan, Clin J Am Soc Nephrol, 10, 1749, 10.2215/CJN.09941014 Ju, 2015, Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker, Sci Transl Med, 7, 316ra193, 10.1126/scitranslmed.aac7071 Betz, 2016, Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes, Kidney Int, 89, 1125, 10.1016/j.kint.2016.01.015 Worawichawong, 2016, Urine epidermal growth factor monocyte chemoattractant protein-1 or their ratio as biomarkers for interstitial fibrosis and tubular atrophy in primary glomerulonephritis, Kidney Blood Press Res, 41, 997, 10.1159/000452595 Segarra-Medrano, 2017, Value of urinary levels of interleukin-6, epidermal growth factor, monocyte chemoattractant protein type1 and transforming growth factor (1 in predicting the extent of fibrosis lesions in kidney biopsies of patients with IgA nephropathy, Nefrologia, 37, 531, 10.1016/j.nefro.2016.11.017 Chanrat, 2018, Urine epidermal growth factor, monocyte chemoattractant protein-1 or their ratio as predictors of complete remission in primary glomerulonephritis, Cytokine, 104, 1, 10.1016/j.cyto.2018.01.015 Dincer, 2018, Assessment of urinary epidermal growth factor level in patients with chronic kidney disease, Urol Nephrol Open Access J, 6, 131, 10.15406/unoaj.2018.06.00220 Nowak, 2018, Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development, Kidney Int, 93, 1198, 10.1016/j.kint.2017.11.024 Satirapoj, 2018, Urinary epidermal growth factor, monocyte chemoattractant protein-1 or their ratio as predictors for rapid loss of renal function in type 2 diabetic patients with diabetic kidney disease, BMC Nephrol, 19, 246, 10.1186/s12882-018-1043-x Wu, 2018, Urinary epidermal growth factor predicts renal prognosis in antineutrophil cytoplasmic antibody-associated vasculitis, Ann Rheum Dis, 77, 1339, 10.1136/annrheumdis-2017-212578 Wu, 2020, Associations of urinary epidermal growth factor and monocyte chemotactic protein-1 with kidney involvement in patients with diabetic kidney disease, Nephrol Dial Transplant, 35, 291 Yang, 2020, Urinary matrix metalloproteinase 7 and prediction of IgA nephropathy progression, Am J Kidney Dis, 75, 384, 10.1053/j.ajkd.2019.07.018 Zheng, 2020, Changes of urinary monocyte chemotactic protein 1 and epidermal growth factor and their correlations with clinicopathology in idiopathic membranous nephropathy patients, Zhonghua Yi Xue Za Zhi, 100, 1230 Ascher, 2021, Urine biomarkers of kidney tubule health and incident CKD stage 3 in women living with HIV: a repeated measures study, Kidney Med, 3, 395, 10.1016/j.xkme.2021.01.012 Hefny, 2021, Urinary epidermal growth factor as a marker for lupus nephritis: clinical, laboratory, and histopathological study, Egypt Rheumatol Rehabil, 48, 13, 10.1186/s43166-021-00063-4 Heidari, 2021, Urinary epidermal growth factor is a novel biomarker for early diagnosis of antibody mediated kidney allograft rejection: a urinary proteomics analysis, J Proteomics, 240, 104208, 10.1016/j.jprot.2021.104208 Mejia-Vilet, 2021, Association between urinary epidermal growth factor and renal prognosis in lupus nephritis, Arthritis Rheumatol, 73, 244, 10.1002/art.41507 Konda, 1997, Urinary excretion of epidermal growth factor in children with reflux nephropathy, J Urol, 157, 2282, 10.1016/S0022-5347(01)64763-3 Tsau, 1999, Urinary epidermal growth factor excretion in children with chronic renal failure, Am J Nephrol, 19, 400, 10.1159/000013485 Chiou, 2004, Factors associated with the outcomes of children with unilateral ureteropelvic junction obstruction, J Urol, 171, 397, 10.1097/01.ju.0000101381.32320.78 Li, 2012, Prediction of the outcome of antenatal hydronephrosis: significance of urinary EGF, Pediatr Nephrol, 27, 2251, 10.1007/s00467-012-2243-4 Madsen, 2013, Epidermal growth factor and monocyte chemotactic peptide-1: potential biomarkers of urinary tract obstruction in children with hydronephrosis, J Pediatr Urol, 9, 838, 10.1016/j.jpurol.2012.11.011 Pastore, 2017, Urinary excretion of EGF and MCP-1 in children with vesicoureteral reflux, Int Braz J Urol, 43, 549, 10.1590/s1677-5538.ibju.2015.0132 Ledeganck, 2018, Longitudinal study of the role of epidermal growth factor on the fractional excretion of magnesium in children: effect of calcineurin inhibitors, Nutrients, 10, 677, 10.3390/nu10060677 Li, 2018, Urinary epidermal growth factor as a prognostic marker for the progression of Alport syndrome in children, Pediatr Nephrol, 33, 1731, 10.1007/s00467-018-3988-1 Azukaitis, 2019, Low levels of urinary epidermal growth factor predict chronic kidney disease progression in children, Kidney Int, 96, 214, 10.1016/j.kint.2019.01.035 Bartoli, 2019, Prospective study on several urinary biomarkers as indicators of renal damage in children with CAKUT, Eur J Pediatr Surg, 29, 215, 10.1055/s-0038-1646960 Gipson, 2019, Urinary epidermal growth factor as a marker of disease progression in children with nephrotic syndrome, Kidney Int Rep, 5, 414, 10.1016/j.ekir.2019.11.018 Srivastava, 2020, Urinary prostaglandin E2 is a biomarker of early adaptive hyperfiltration in solitary functioning kidney, Prostaglandins Other Lipid Mediat, 146, 106403, 10.1016/j.prostaglandins.2019.106403 Ledeganck, 2021, The next generation: urinary epidermal growth factor is associated with an early decline in kidney function in children and adolescents with type 1 diabetes mellitus, Diabetes Res Clin Pract, 178, 108945, 10.1016/j.diabres.2021.108945 Di Paolo, 1997, Renal expression and urinary concentration of EGF and IL-6 in acutely dysfunctioning kidney transplanted patients, Nephrol Dial Transplant, 12, 2687, 10.1093/ndt/12.12.2687 Kwon, 2010, Simultaneous monitoring of multiple urinary cytokines may predict renal and patient outcome in ischemic AKI, Ren Fail, 32, 699, 10.3109/0886022X.2010.486496 Singal, 2018, Biomarkers of renal injury in cirrhosis: association with acute kidney injury and recovery after liver transplantation, Nephron, 138, 1, 10.1159/000479074 Wai, 2013, A pilot study of urinary fibroblast growth factor-2 and epithelial growth factor as potential biomarkers of acute kidney injury in critically ill children, Pediatr Nephrol, 28, 2189, 10.1007/s00467-013-2543-3 Chu, 2021, Kidney outcomes and hypertension in survivors of wilms tumor: a prospective cohort study, J Pediatr, 230, 215, 10.1016/j.jpeds.2020.12.005 Askenazi, 2012, Urine biomarkers predict acute kidney injury in newborns, J Pediatr, 161, 270, 10.1016/j.jpeds.2012.02.007 Hoffman, 2013, A novel urinary biomarker profile to identify acute kidney injury (AKI) in critically ill neonates: a pilot study, Pediatr Nephrol, 28, 2179, 10.1007/s00467-013-2524-6 Mohammadjafari, 2014, Determination of the severity of ureteropelvic junction obstruction using urinary epidermal growth factor and kidney injury molecule 1 levels, Biomark Med, 8, 1199, 10.2217/bmm.14.79 Askenazi, 2016, Acute kidney injury urine biomarkers in very low-birth-weight infants, Clin J Am Soc Nephrol, 11, 1527, 10.2215/CJN.13381215 Hanna, 2016, Early urinary biomarkers of acute kidney injury in preterm infants, Pediatr Res, 80, 218, 10.1038/pr.2016.70 Sweetman, 2016, Renal function and novel urinary biomarkers in infants with neonatal encephalopathy, Acta Paediatr, 105, e513, 10.1111/apa.13555 DeFreitas, 2016, Longitudinal patterns of urine biomarkers in infants across gestational ages, Pediatr Nephrol, 31, 1179, 10.1007/s00467-016-3327-3 Gupta, 2016, A new approach to define acute kidney injury in term newborns with hypoxic ischemic encephalopathy, Pediatr Nephrol, 31, 1167, 10.1007/s00467-016-3317-5 Ahn, 2020, Urine biomarkers for monitoring acute kidney injury in premature infants, Kidney Res Clin Pract, 39, 284, 10.23876/j.krcp.20.039 Yepes-Calderón, 2019, Urinary epidermal growth factor/creatinine ratio and graft failure in renal transplant recipients: a prospective cohort study, J Clin Med, 8, 1673, 10.3390/jcm8101673 Norvik, 2021, Urinary excretion of epidermal growth factor and rapid loss of kidney function, Nephrol Dial Transplant, 36, 1882, 10.1093/ndt/gfaa208 Ledeganck, 2014, Magnesium loss in cyclosporine-treated patients is related to renal epidermal growth factor downregulation, Nephrol Dial Transplant, 29, 1097, 10.1093/ndt/gft498 Klouche, 2017, On-line hemodiafiltration did not induce an overproduction of oxidative stress and inflammatory cytokines in intensive care unit acute kidney injury, BMC Nephrol, 18, 371, 10.1186/s12882-017-0785-1 Ramos, 2019, Effect of prebiotic (fructooligosaccharide) on uremic toxins of chronic kidney disease patients: a randomized controlled trial, Nephrol Dial Transplant, 34, 1876, 10.1093/ndt/gfy171 Lev-Ran, 1990, Excretion of epidermal growth factor (EGF) in diabetes, Clin Chim Acta, 192, 201, 10.1016/0009-8981(90)90222-E Chow, 1994, An assessment of immunoreactive epidermal growth factor in urine of patients with urological diseases, Urol Res, 22, 221, 10.1007/BF00541896 Segarra, 2019, Accuracy of urinary epidermal growth factor to creatinine ratio to predict 24-hour urine epidermal growth factor and interstitial kidney fibrosis in patients with IgA nephropathy, Clin Lab, 65, 181122, 10.7754/Clin.Lab.2018.181122 Segarra, 2019, Analytical and biological variability of urinary epidermal growth factor-to-creatinine ratio in patients with chronic kidney disease and in healthy volunteers, Clin Lab, 65, 190304, 10.7754/Clin.Lab.2019.190304 Tsau, 1996, Decreased urinary epidermal growth factor in children with acute renal failure: epidermal growth factor/creatinine ratio not a reliable parameter for urinary epidermal growth factor excretion, Pediatr Res, 39, 20, 10.1203/00006450-199601000-00003 Callegari, 1988, The source of urinary epidermal growth factor in humans, Eur J Appl Physiol Occup Physiol, 58, 26, 10.1007/BF00636599 Chen, 2016, Expression and function of the epidermal growth factor receptor in physiology and disease, Physiol Rev, 96, 1025, 10.1152/physrev.00030.2015 Sun, 2021, Epidermal growth factor protects against high glucose-induced podocyte injury possibly via modulation of autophagy and PI3K/AKT/mTOR signalling pathway through DNA methylation, Diabetes Metab Syndr Obes, 14, 2255, 10.2147/DMSO.S299562 Fuse H, Mizuno I, Sakamoto M, Katayama T. Epidermal growth factor in urine from the patients with urothelial tumors. Urol Int. 1992;48:261-4, http://dx.doi.org/ 10.1159/000282347.