Urinary Angiotensinogen as a Novel Early Biomarker of Intrarenal Renin^|^ndash;Angiotensin System Activation in Experimental Type 1 Diabetes

Journal of Pharmacological Sciences - Tập 119 Số 4 - Trang 314-323 - 2012
Masumi Kamiyama1,2, Andrea Zsombok3,1,2, Hiroyuki Kobori3,1,2
1Department of Physiology, Tulane University Health Sciences Center, USA
2Hypertension and Renal Center of Excellence, Tulane University Health Sciences Center, USA
3Department of Medicine, Tulane University Health Sciences Center, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

1 Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038–2047.

10.1016/S0272-6386(03)00826-6

3 The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977–986.

10.1056/NEJMoa021835

5 Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2001;414:813–820.

10.1124/pr.59.3.3

7 Taguma Y, Kitamoto Y, Futaki G, Ueda H, Monma H, Ishizaki M, et al. Effect of captopril on heavy proteinuria in azotemic diabetics. N Engl J Med. 1985;313:1617–1620.

8 Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The collaborative study group. N Engl J Med. 1993;329:1456–1462.

9 Nelson RG, Tuttle KR. Prevention of diabetic kidney disease: negative clinical trials with renin-angiotensin system inhibitors. Am J Kidney Dis. 2010;55:426–430.

10 Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345:851–860.

10.1056/NEJMoa042274

10.1016/S0140-6736(08)61236-2

13 Haller H, Ito S, Izzo JL Jr, Januszewicz A, Katayama S, Menne J, et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med. 2011;364:907–917.

10.1056/NEJMe1014147

15 Miller JA, Curtis JR, Sochett EB. Relationship between diurnal blood pressure, renal hemodynamic function, and the renin-angiotensin system in type 1 diabetes. Diabetes. 2003;52:1806–1811.

16 Nagai Y, Yao L, Kobori H, Miyata K, Ozawa Y, Miyatake A, et al. Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats. J Am Soc Nephrol. 2005;16:703–711.

17 Suzaki Y, Ozawa Y, Kobori H. Intrarenal oxidative stress and augmented angiotensinogen are precedent to renal injury in Zucker diabetic fatty rats. Int J Biol Sci. 2007;3:40–46.

18 Miyata K, Ohashi N, Suzaki Y, Katsurada A, Kobori H. Sequential activation of the reactive oxygen species/angiotensinogen/renin-angiotensin system axis in renal injury of type 2 diabetic rats. Clin Exp Pharmacol Physiol. 2008;35:922–927.

19 Ihara G, Kiyomoto H, Kobori H, Nagai Y, Ohashi N, Hitomi H, et al. Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade. J Hypertens. 2010;28:2289–2298.

20 Yoo TH, Li JJ, Kim JJ, Jung DS, Kwak SJ, Ryu DR, et al. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int. 2007;71:1019–1027.

21 Kobori H, Katsurada A, Miyata K, Ohashi N, Satou R, Saito T, et al. Determination of plasma and urinary angiotensinogen levels in rodents by newly developed ELISA. Am J Physiol Renal Physiol. 2008;294:F1257–F1263.

22 Park S, Bivona BJ, Kobori H, Seth DM, Chappell MC, Lazartigues E, et al. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol. 2010;298:F37–F48.

10.1161/hy0202.103821

24 Castrop H, Hocherl K, Kurtz A, Schweda F, Todorov V, Wagner C. Physiology of kidney renin. Physiol Rev. 2010;90:607–673.

25 Gould AB, Green D. Kinetics of the human renin and human substrate reaction. Cardiovasc Res. 1971;5:86–89.

26 Brasier AR, Li J. Mechanisms for inducible control of angiotensinogen gene transcription. Hypertension. 1996;27:465–475.

27 Ogawa S, Kobori H, Ohashi N, Urushihara M, Nishiyama A, Mori T, et al. Angiotensin II type 1 receptor blockers reduce urinary angiotensinogen excretion and the levels of urinary markers of oxidative stress and inflammation in patients with type 2 diabetic nephropathy. Biomark Insights. 2009;4:97–102.

28 Saito T, Urushihara M, Kotani Y, Kagami S, Kobori H. Increased urinary angiotensinogen is precedent to increased urinary albumin in patients with type 1 diabetes. Am J Med Sci. 2009;338:478–480.

29 Sugimoto H, Grahovac G, Zeisberg M, Kalluri R. Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. Diabetes. 2007;56:1825–1833.

30 Gabra BH, Sirois P. Pathways for the bradykinin B1 receptor-mediated diabetic hyperalgesia in mice. Inflamm Res. 2004;53:653–657.

10.1016/j.bone.2006.12.057

32 Liu F, Brezniceanu ML, Wei CC, Chenier I, Sachetelli S, Zhang SL, et al. Overexpression of angiotensinogen increases tubular apoptosis in diabetes. J Am Soc Nephrol. 2008;19:269–280.

33 Munshi R, Johnson A, Siew ED, Ikizler TA, Ware LB, Wurfel MM, et al. MCP-1 gene activation marks acute kidney injury. J Am Soc Nephrol. 2011;22:165–175.

34 Li Q, Li YX, Stahl GL, Thurman JM, He Y, Tong HH. Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice. Infect Immun. 2011;79:2578–2585.

10.1016/j.trsl.2008.01.003

36 Prieto-Carrasquero MC, Harrison-Bernard LM, Kobori H, Ozawa Y, Hering-Smith KS, Hamm LL, et al. Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Hypertension. 2004;44:223–229.

10.1681/ASN.2004080676

10.1016/j.bbrc.2007.04.105

10.1152/ajprenal.00059.2006

40 Ozawa Y, Kobori H. Crucial role of Rho-nuclear factor-kappaB axis in angiotensin II-induced renal injury. Am J Physiol Renal Physiol. 2007;293:F100–F109.

10.1038/ki.2008.499

10.1016/j.carres.2008.12.007

10.1055/s-2005-861370

44 Tzovaras V, Tsimihodimos V, Kostara C, Mitrogianni Z, Elisaf M. Aminoglycoside-induced nephrotoxicity studied by proton magnetic resonance spectroscopy of urine. Nephrol Dial Transplant. 2011;26:3219–3224.

45 Zappitelli M, Washburn KK, Arikan AA, Loftis L, Ma Q, Devarajan P, et al. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care. 2007;11:R84.

10.1016/S1382-6689(00)00064-8

47 Moriwaki Y, Inokuchi T, Yamamoto A, Ka T, Tsutsumi Z, Takahashi S, et al. Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Acta Diabetol. 2007;44:215–218.

10.1016/j.amjhyper.2005.11.014

10.1172/JCI114454

10.1038/ki.1993.177

10.1038/ki.1991.117

10.1038/ki.1994.445

53 Darby IA, Sernia C. In situ hybridization and immunohistochemistry of renal angiotensinogen in neonatal and adult rat kidneys. Cell Tissue Res. 1995;281:197–206.

10.1074/jbc.M110.150284

55 Kamiyama M, Garner MK, Farragut KM, Kobori H. The establishment of a primary culture system of proximal tubule segments using specific markers from normal mouse kidneys. Int J Mol Sci. 2012;13:5098–5111.

10.1210/er.2003-0018

57 Carey RM, Siragy HM. The intrarenal renin-angiotensin system and diabetic nephropathy. Trends Endocrinol Metab. 2003;14:274–281.

10.1097/HJH.0b013e3283060efa

10.1124/jpet.109.158113

60 Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861–869.

10.1161/01.HYP.0000122875.91100.28

10.1093/ndt/gfq371

63 Granier C, Makni K, Molina L, Jardin-Watelet B, Ayadi H, Jarraya F. Gene and protein markers of diabetic nephropathy. Nephrol Dial Transplant. 2008;23:792–799.

10.1093/ndt/gfq258

10.1002/dmrr.1068

10.1046/j.1523-1755.1999.00271.x

67 Zhang SL, Tang SS, Chen X, Filep JG, Ingelfinger JR, Chan JS. High levels of glucose stimulate angiotensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. Endocrinology. 2000;141:4637–4646.

10.1210/en.143.8.2975

69 Zhang SL, To C, Chen X, Filep JG, Tang SS, Ingelfinger JR, et al. Essential role(s) of the intrarenal renin-angiotensin system in transforming growth factor-beta1 gene expression and induction of hypertrophy of rat kidney proximal tubular cells in high glucose. J Am Soc Nephrol. 2002;13:302–312.

70 Zhang SL, Chen X, Hsieh TJ, Leclerc M, Henley N, Allidina A, et al. Hyperglycemia induces insulin resistance on angiotensinogen gene expression in diabetic rat kidney proximal tubular cells. J Endocrinol. 2002;172:333–344.

71 Zhang SL, Chen X, Wei CC, Filep JG, Tang SS, Ingelfinger JR, et al. Insulin inhibits dexamethasone effect on angiotensinogen gene expression and induction of hypertrophy in rat kidney proximal tubular cells in high glucose. Endocrinology. 2002;143:4627–4635.

72 Hsieh TJ, Fustier P, Zhang SL, Filep JG, Tang SS, Ingelfinger JR, et al. High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells. Endocrinology. 2003;144:4338–4349.