Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination

Journal of Controlled Release - Tập 114 - Trang 348-358 - 2006
Olga Borges1, Anabela Cordeiro-da-Silva2, Stefan G. Romeijn3, Maryam Amidi3, Adriano de Sousa1, Gerrit Borchard3,4, Hans E. Junginger3,5
1Center for Pharmaceutical Studies, Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Rua do Norte, 3000-295 Coimbra, Portugal
2IBMC and Laboratory of Biochemical, Faculty of Pharmacy, University of Porto, 4050-047 Porto, Portugal
3Leiden/Amsterdam Center for Drug Research, Division of Pharmaceutical Technology, P.O. Box 9502, 2300 RA Leiden, The Netherlands
4School of Pharmacy Geneva/Lausanne, University of Geneva, 1211 Geneva 4, Switzerland
5Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65 000, Thailand