Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

Neuropsychopharmacology - Tập 39 Số 13 - Trang 2949-2962 - 2014
Teng Jiang1, Lan Tan1, Xi-Chen Zhu1, Qiao-Quan Zhang2, Lei Cao1, Meng‐Shan Tan3, Li-Ze Gu4, Hui-Fu Wang1, ZhengZheng Ding4, Yingdong Zhang5, Jin‐Tai Yu3
1Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, People’s Republic of China
2The Clinical Laboratory of Nanjing Brain Hospital, Nanjing Medical University, Nanjing, People's Republic of China
3Department of Neurology, Qingdao Municipal Hospital, College of Medicine and Pharmaceutics, Ocean University of China, Qingdao, People's Republic of China
4Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, People’s Republic of China
5Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People’s Republic of China

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