Up-Regulated Pancreatic Tissue MicroRNA-375 Associates With Human Type 2 Diabetes Through β-Cell Deficit and Islet Amyloid Deposition

Ambros, 2004, The functions of animal microRNAs., Nature, 431, 350, 10.1038/nature02871

Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function., Cell, 116, 281, 10.1016/S0092-8674(04)00045-5

Cullen, 2004, Transcription and processing of human microRNA precursors., Mol Cell, 16, 861, 10.1016/j.molcel.2004.12.002

Kloosterman, 2006, The diverse functions of microRNAs in animal development and disease., Dev Cell, 11, 441, 10.1016/j.devcel.2006.09.009

Chen, 2008, Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases., Cell Res, 18, 997, 10.1038/cr.2008.282

Lu, 2005, MicroRNA expression profiles classify human cancers., Nature, 435, 834, 10.1038/nature03702

Poy, 2004, A pancreatic islet-specific microRNA regulates insulin secretion., Nature, 432, 226, 10.1038/nature03076

El Ouaamari, 2008, miR-375 targets 3-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic -cells., Diabetes, 57, 2708, 10.2337/db07-1614

Poy, 2009, miR-375 maintains normal pancreatic - and -cell mass., Proc Natl Acad Sci U S A, 106, 5813, 10.1073/pnas.0810550106

Zhao, 2003, Prevalence and clinicopathological characteristics of islet amyloid in Chinese patients with type 2 diabetes., Diabetes, 52, 2759, 10.2337/diabetes.52.11.2759

Zhao, 2008, Higher islet amyloid load in men than in women with type 2 diabetes mellitus., Pancreas, 37, e68, 10.1097/MPA.0b013e3181788e18

Lynn, 2007, MicroRNA expression is required for pancreatic islet cell genesis in the mouse., Diabetes, 56, 2938, 10.2337/db07-0175

Kloosterman, 2007, Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development., PLoS Biol, 5, e203, 10.1371/journal.pbio.0050203

Bravo-Egana, 2008, Quantitative differential expression analysis reveals miR-7 as major islet microRNA., Biochem Biophys Res Commun, 366, 922, 10.1016/j.bbrc.2007.12.052

Ladeiro, 2008, MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations., Hepatology, 47, 1955, 10.1002/hep.22256

Keller, 2007, Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy., J Biol Chem, 282, 32084, 10.1074/jbc.M700899200