Unexplored horizons of cDC1 in immunity and tolerance
Tài liệu tham khảo
Abd Hamid, 2019, Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8 + tumor-infiltrating T lymphocyte responses, Cancer Immunology Research, 7, 1293, 10.1158/2326-6066.CIR-18-0885
Alexandre, 2016, XCR1+ dendritic cells promote memory CD8+ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses, The Journal of Experimental Medicine, 213, 75, 10.1084/jem.20142350
Anderson, 2007, Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells, Science (80-.), 318, 1141, 10.1126/science.1148536
Arase, 2005, Heterotypic interaction of CRTAM with Necl2 induces cell adhesion on activated NK cells and CD8+ T cells, International Immunology, 17, 1227, 10.1093/intimm/dxh299
Ardouin, 2016, Broad and largely concordant molecular changes characterize Tolerogenic and immunogenic dendritic cell maturation in Thymus and periphery, Immunity, 45, 305, 10.1016/j.immuni.2016.07.019
Aref, 2017, Upregulation of CD200 is associated with regulatory T cell expansion and disease progression in multiple myeloma, Hematological Oncology, 35, 51, 10.1002/hon.2206
Ashour, 2020, IL-12 from endogenous cDC1, and not vaccine DC, is required for Th1 induction, JCI Insight, 5, 10.1172/jci.insight.135143
Bachem, 2010, Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells, The Journal of Experimental Medicine, 207, 1273, 10.1084/jem.20100348
Balan, 2019, Dendritic cell subsets and locations, International Review of Cell and Molecular Biology, 10.1016/bs.ircmb.2019.07.004
Balan, 2014, Human XCR1 + dendritic cells derived in vitro from CD34 + progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, Contrary to Monocyte-Derived Dendritic Cells, J. Immunol., 193, 1622, 10.4049/jimmunol.1401243
Balan, 2018, Large-scale human dendritic cell differentiation revealing notch-dependent lineage bifurcation and heterogeneity, Cell Rep, 24, 1902, 10.1016/j.celrep.2018.07.033
Baranek, 2012, Differential responses of immune cells to type I interferon contribute to host resistance to viral infection, Cell Host & Microbe, 12, 571, 10.1016/j.chom.2012.09.002
Barry, 2018, A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments, Nature Medicine, 24, 1178, 10.1038/s41591-018-0085-8
Basha, 2012, A CD74-dependent MHC class I endolysosomal cross-presentation pathway, Nature Immunology, 13, 237, 10.1038/ni.2225
Basso, 2010, BCL6. master regulator of the germinal center reaction and key oncogene in B Cell lymphomagenesis, Advances in Immunology, 105, 193, 10.1016/S0065-2776(10)05007-8
Bigley, 2018, Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation, The Journal of Allergy and Clinical Immunology, 141, 2234, 10.1016/j.jaci.2017.08.044
Blackburn, 2019, Soluble CD93 is an apoptotic cell opsonin recognized by α x β 2, European Journal of Immunology, 49, 600, 10.1002/eji.201847801
Bol, 2019, The clinical application of cancer immunotherapy based on naturally circulating dendritic cells, Journal for Immunotherapy of Cancer, 7, 109, 10.1186/s40425-019-0580-6
Boles, 2005, The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM, Blood, 106, 779, 10.1182/blood-2005-02-0817
Böttcher, 2018, The role of type 1 conventional dendritic cells in cancer immunity, Trends in Cancer, 4, 784, 10.1016/j.trecan.2018.09.001
Böttcher, 2018, NK cells stimulate recruitment of cDC1 into the tumor microenvironment promoting cancer immune control, Cell, 172, 1022, 10.1016/j.cell.2018.01.004
Brewitz, 2017, CD8 + T cells orchestrate pDC-XCR1 + dendritic cell spatial and functional cooperativity to optimize priming, Immunity, 46, 205, 10.1016/j.immuni.2017.01.003
Bronger, 2019, Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors, Cancer Metastasis Reviews, 38, 417, 10.1007/s10555-019-09807-3
Brown, 2018, C-type lectins in immunity and homeostasis, Nature Reviews Immunology, 18, 374, 10.1038/s41577-018-0004-8
Canavan, 2018, Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis, JCI Insight, 3, e95228, 10.1172/jci.insight.95228
Cancel, 2019, Are conventional type 1 dendritic cells critical for protective antitumor immunity and how?, Frontiers in Immunology, 10, 10.3389/fimmu.2019.00009
Cao, 1999, Clnk, a novel Slp-76–related adaptor molecule expressed in cytokine-stimulated Hemopoietic cells, The Journal of Experimental Medicine, 190, 1527, 10.1084/jem.190.10.1527
Chen, 2012, Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation, Blood, 119, 127, 10.1182/blood-2011-06-363994
Chen, 2019, Type I IFN protects cancer cells from CD8+ T cell–mediated cytotoxicity after radiation, The Journal of Clinical Investigation, 129, 4224, 10.1172/JCI127458
Chiang, 2016, Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets, European Journal of Immunology, 46, 329, 10.1002/eji.201546023
Chiba, 2012, Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1, Nature Immunology, 13, 832, 10.1038/ni.2376
Choi, 2019, IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells, Journal for Immunotherapy of Cancer, 7, 168, 10.1186/s40425-019-0652-7
Coelho-Dos-Reis, 2020, Functional human CD141+ dendritic cells in human immune system mice, The Journal of Infectious Diseases, 221, 201, 10.1093/infdis/jiz432
Colletti, 2016, TLR3 signaling promotes the induction of unique human BDCA-3 dendritic cell populations, Frontiers in Immunology, 7, 10.3389/fimmu.2016.00088
Cooles, 2018, Phenotypic and transcriptomic analysis of peripheral blood Plasmacytoid and conventional dendritic cells in early drug Naïve rheumatoid arthritis, Frontiers in Immunology, 9, 755, 10.3389/fimmu.2018.00755
Corrales, 2016, Antagonism of the STING pathway via activation of the AIM2 Inflammasome by intracellular DNA, Journal of Immunology, 196, 3191, 10.4049/jimmunol.1502538
Cortez, 2014, CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection, Journal of Experimental Medicine, 10.1084/jem.20130904
Crozat, 2010, The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells, The Journal of Experimental Medicine, 207, 1283, 10.1084/jem.20100223
Cueto, 2020, DNGR-1, a dendritic cell-specific sensor of tissue damage that dually modulates immunity and inflammation, Frontiers in Immunology, 10, 10.3389/fimmu.2019.03146
Cytlak, 2020, Differential IRF8 transcription factor requirement defines two pathways of dendritic cell development in humans, Immunity, 53, 353, 10.1016/j.immuni.2020.07.003
De Trez, 2008, The inhibitory HVEM-BTLA pathway counter regulates Lymphotoxin β receptor signaling to achieve homeostasis of dendritic cells, Journal of Immunology, 180, 238, 10.4049/jimmunol.180.1.238
Deauvieau, 2015, Human natural killer cells promote cross-presentation of tumor cell-derived antigens by dendritic cells, International Journal of Cancer, 136, 1085, 10.1002/ijc.29087
del Fresno, 2018, DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment, Science (80), 362, 351, 10.1126/science.aan8423
Dessarthe, 2013, CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vγ9Vδ2 T cells, Journal of Immunology, 190, 4868, 10.4049/jimmunol.1202596
Di Blasio, 2020, The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture, Nature Communications, 11, 2749, 10.1038/s41467-020-16583-0
Di Virgilio, 2015, Purinergic signaling in the immune system, Autonomic Neuroscience, 191, 117, 10.1016/j.autneu.2015.04.011
Draheim, 2017, Profiling MHC II immunopeptidome of blood-stage malaria reveals that cDC 1 control the functionality of parasite-specific CD 4 T cells, EMBO Molecular Medicine, 9, 1605, 10.15252/emmm.201708123
Dutertre, 2019, Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells, Immunity, 51, 10.1016/j.immuni.2019.08.008
Dzionek, 2000, BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood, Journal of Immunology, 165, 6037, 10.4049/jimmunol.165.11.6037
Eagle, 2009, ULBP6/RAET1L is an additional human NKG2D ligand, European Journal of Immunology, 39, 3207, 10.1002/eji.200939502
Esterházy, 2016, Classical dendritic cells are required for dietary antigen–mediated induction of peripheral Treg cells and tolerance, Nature Immunology, 17, 545, 10.1038/ni.3408
Feng, 2019, Phagocytosis checkpoints as new targets for cancer immunotherapy, Nature Reviews. Cancer, 19, 568, 10.1038/s41568-019-0183-z
Ferris, 2020, cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity, Nature, 584, 624, 10.1038/s41586-020-2611-3
Flinsenberg, 2012, Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells, Blood, 120, 5163, 10.1182/blood-2012-06-434498
Flynn, 2013, CD8 T cell memory to a viral pathogen requires trans Cosignaling between HVEM and BTLA, PLoS One, 8, 10.1371/journal.pone.0077991
Fossum, 2015, Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8 + T-cell responses against influenza virus, European Journal of Immunology, 45, 624, 10.1002/eji.201445080
Fossum, 2020, Targeting antigens to different receptors on conventional type 1 dendritic cells impacts the immune response, Journal of Immunology, 205, 661, 10.4049/jimmunol.1901119
Fu, 2020, Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity, Acta Pharmaceutica Sinica B, 10, 414, 10.1016/j.apsb.2019.08.010
Gaidt, 2017, The DNA inflammasome in human myeloid cells is initiated by a STING-cell death program upstream of NLRP3, Cell, 171, 1110, 10.1016/j.cell.2017.09.039
Galibert, 2005, Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule, The Journal of Biological Chemistry, 280, 21955, 10.1074/jbc.M502095200
Ghinnagow, 2017, Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses, Oncoimmunology, 6, 10.1080/2162402X.2017.1339855
Grajales-Reyes, 2015, Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor, Nature Immunology, 16, 708, 10.1038/ni.3197
Greenlee-Wacker, 2011, Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis, Journal of Immunology, 187, 3353, 10.4049/jimmunol.1100803
Greyer, 2016, T cell help amplifies innate signals in CD8 + DCs for optimal CD8 + T cell priming, Cell Reports, 14, 586, 10.1016/j.celrep.2015.12.058
Griffiths, 2018, CD93 regulates central nervous system inflammation in two mouse models of autoimmune encephalomyelitis, Immunology, 155, 346, 10.1111/imm.12974
Gudjonsson, 2017, Targeting influenza virus hemagglutinin to Xcr1 + dendritic cells in the absence of receptor-mediated endocytosis enhances protective antibody responses, Journal of Immunology, 198, 2785, 10.4049/jimmunol.1601881
Hambleton, 2011, IRF8 mutations and human dendritic-cell immunodeficiency, The New England Journal of Medicine, 365, 127, 10.1056/NEJMoa1100066
Hammerich, 2019, Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination, Nature Medicine, 25, 814, 10.1038/s41591-019-0410-x
Hanč, 2016, DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells, C-Type Lectin Receptors in Immunity, 65, 10.1007/978-4-431-56015-9_5
Harhausen, 2010, CD93/AA4.1: A novel regulator of inflammation in murine focal cerebral ischemia, Journal of Immunology, 184, 6407, 10.4049/jimmunol.0902342
Heidkamp, 2016, Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment, Sci. Immunol, 1, 10.1126/sciimmunol.aai7677
Hemann, 2019, Interferon-λ modulates dendritic cells to facilitate T cell immunity during infection with influenza a virus, Nature Immunology, 20, 1035, 10.1038/s41590-019-0408-z
Henrick, 2019, TLR10 senses HIV-1 proteins and significantly enhances HIV-1 infection, Frontiers in Immunology, 10, 482, 10.3389/fimmu.2019.00482
Hildner, 2008, Batf3 deficiency reveals a critical role for CD8 + dendritic cells in cytotoxic T cell immunity, Science (80), 322, 1097, 10.1126/science.1164206
Hollande, 2019, Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth, Nature Immunology, 20, 257, 10.1038/s41590-019-0321-5
Hu, 2016, The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury, Science (80), 354, 765, 10.1126/science.aaf7532
Hubert, 2020, IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer, Sci. Immunol., 5, 10.1126/sciimmunol.aav3942
Iborra, 2016, Optimal generation of tissue-resident but not circulating memory T cells during viral infection requires Crosspriming by DNGR-1+ dendritic cells, Immunity, 45, 847, 10.1016/j.immuni.2016.08.019
Idoyaga, 2011, Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A, Proceedings of the National Academy of Sciences, 108, 2384, 10.1073/pnas.1019547108
Ikezoe, 2015, Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen, Bone Marrow Transplantation, 50, 113, 10.1038/bmt.2014.208
Jaiswal, 2013, Batf3 and Id2 have a synergistic effect on Irf8 -directed classical CD8α + dendritic cell development, Journal of Immunology, 191, 5993, 10.4049/jimmunol.1203541
Janela, 2019, A subset of type I conventional dendritic cells controls cutaneous bacterial infections through VEGFα-mediated recruitment of neutrophils, Immunity, 50, 1069, 10.1016/j.immuni.2019.03.001
Jiang, 2016, TLR10 is a negative regulator of both MyD88-dependent and -independent TLR signaling, Journal of Immunology, 196, 3834, 10.4049/jimmunol.1502599
Jiang, 2018, Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response, Nature Medicine, 24, 1550, 10.1038/s41591-018-0136-1
Joffre, 2010, Efficient and versatile manipulation of the peripheral CD4 + T-cell compartment by antigen targeting to DNGR-1/CLEC9A, Eur. J. Immunol, 40, 1255, 10.1002/eji.201040419
Johnson, 2018, Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement, JCI Insight, 3, 10.1172/jci.insight.120360
Jones, 2016, Immunomodulatory functions of BTLA and HVEM govern induction of Extrathymic regulatory T cells and tolerance by dendritic cells, Immunity, 45, 1066, 10.1016/j.immuni.2016.10.008
Jongbloed, 2010, Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens, The Journal of Experimental Medicine, 207, 1247, 10.1084/jem.20092140
Kato, 2015, Targeting antigen to Clec9A primes follicular Th cell memory responses capable of robust recall, Journal of Immunology, 195, 1006, 10.4049/jimmunol.1500767
Kato, 2020, Display of native antigen on cDC1 that have spatial access to both T and B cells underlies efficient humoral vaccination, J. Immunol., 10.4049/jimmunol.2000549
Keller, 2008, Expression of costimulatory ligand CD70 on steady-state dendritic cells breaks CD8+ T cell tolerance and permits effective immunity, Immunity, 29, 934, 10.1016/j.immuni.2008.10.009
Khan, 2019, C-type lectin domain group 14 proteins in vascular biology, cancer and inflammation, The FEBS Journal, 286, 3299, 10.1111/febs.14985
Kourko, 2019, IL-27, IL-30, and IL-35: A cytokine triumvirate in cancer, Frontiers in Oncology, 9, 10.3389/fonc.2019.00969
Kraan, 1998, The role of IL-13 in IgE synthesis by allergic asthma patients, Clinical and Experimental Immunology, 111
Kulemzin, 2011, FCRL6 receptor: Expression and associated proteins, Immunology Letters, 134, 174, 10.1016/j.imlet.2010.09.023
Kyi, 2018, Therapeutic immune modulation against solid cancers with Intratumoral poly-ICLC: A pilot trial, Clinical Cancer Research, 24, 4937, 10.1158/1078-0432.CCR-17-1866
Lahoud, 2011, Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype, Journal of Immunology, 187, 842, 10.4049/jimmunol.1101176
Lai, 2020, Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity, Nature Immunology, 10.1038/s41590-020-0676-7
Lammert, 2020, AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment, Nature, 580, 647, 10.1038/s41586-020-2174-3
Lasfar, 2019, Interferon lambda: Toward a dual role in Cancer, Journal of Interferon & Cytokine Research, 39, 22, 10.1089/jir.2018.0046
Lauterbach, 2010, Mouse CD8α+ DCs and human BDCA3+ DCs are major producers of IFN-λ in response to poly IC, The Journal of Experimental Medicine, 207, 2703, 10.1084/jem.20092720
Lazear, 2015, Interferon-λ: Immune functions at barrier surfaces and beyond, Immunity, 43, 15, 10.1016/j.immuni.2015.07.001
Lee, 2017, Lineage specification of human dendritic cells is marked by IRF8 expression in hematopoietic stem cells and multipotent progenitors, Nature Immunology, 18, 877, 10.1038/ni.3789
Li, 2014, Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs, Nature Chemical Biology, 10, 1043, 10.1038/nchembio.1661
Li, 2015, Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates, European Journal of Immunology, 45, 854, 10.1002/eji.201445127
Li, 2016, Analysis of the Rab GTPase Interactome in dendritic cells reveals anti-microbial functions of the Rab32 complex in bacterial containment, Immunity, 44, 422, 10.1016/j.immuni.2016.01.027
Loghmani, 2018, Exploring traditional and nontraditional roles for thrombomodulin, Blood, 132, 148, 10.1182/blood-2017-12-768994
Lundberg, 2010, FcɛRI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis, Human Immunology, 71, 931, 10.1016/j.humimm.2010.07.008
Lundberg, 2016, Allergen-specific immunotherapy alters the frequency, as well as the FcR and CLR expression profiles of human dendritic cell subsets, PLoS One, 11, 10.1371/journal.pone.0148838
Maier, 2020, A conserved dendritic-cell regulatory program limits antitumour immunity, Nature, 580, 257, 10.1038/s41586-020-2134-y
Malaer, 2017, CS1 (SLAMF7, CD319) is an effective immunotherapeutic target for multiple myeloma, American Journal of Cancer Research, 7, 1637
Man, 2016, AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity, European Journal of Immunology, 46, 269, 10.1002/eji.201545839
Manches, 2008, HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase–dependent mechanism, The Journal of Clinical Investigation, 118, 3431, 10.1172/JCI34823
Mangan, 2017, Serpinb9 is a marker of antigen cross-presenting dendritic cells, Molecular Immunology, 82, 50, 10.1016/j.molimm.2016.12.011
Marone, 2019, The intriguing role of interleukin 13 in the pathophysiology of asthma, Frontiers in Pharmacology, 10, 10.3389/fphar.2019.01387
Martinet, 2013, High endothelial Venule blood vessels for tumor-infiltrating lymphocytes are associated with Lymphotoxin β–producing dendritic cells in human breast Cancer, Journal of Immunology, 191, 2001, 10.4049/jimmunol.1300872
Mastelic-Gavillet, 2020, Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer, European Journal of Cancer, 135, 173, 10.1016/j.ejca.2020.04.036
Masterman, 2020, Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141 + dendritic cells to activate naïve and memory NY-ESO-1-specific CD8 + T cells, Journal for Immunotherapy of Cancer, 8, 10.1136/jitc-2020-000691
Mayoux, 2020, Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy, Sci. Transl. Med., 12, 10.1126/scitranslmed.aav7431
Meyer, 2018, Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance, Nature Communications, 9, 1250, 10.1038/s41467-018-03600-6
Michea, 2018, Adjustment of dendritic cells to the breast-cancer microenvironment is subset specific, Nature Immunology, 19, 885, 10.1038/s41590-018-0145-8
Migita, 2005, Reduced blood BDCA-2+ (lymphoid) and CD11c+ (myeloid) dendritic cells in systemic lupus erythematosus, Clinical and Experimental Immunology, 142, 84, 10.1111/j.1365-2249.2005.02897.x
Minoda, 2017, Human CD141+ dendritic cell and CD1c+ dendritic cell undergo concordant early genetic programming after activation in humanized mice in vivo, Frontiers in Immunology, 8, 1419, 10.3389/fimmu.2017.01419
Morandi, 2009, NK cells provide helper signal for CD8+ T cells by inducing the expression of membrane-bound IL-15 on DCs, International Immunology, 21, 599, 10.1093/intimm/dxp029
Murillo, 2009, In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb, European Journal of Immunology, 39, 2424, 10.1002/eji.200838958
Nakayama, 2014, Antigen presentation by MHC-dressed cells, Frontiers in Immunology, 5, 1
Nakayama, 2009, Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation, Blood, 113, 3821, 10.1182/blood-2008-10-185884
Ndhlovu, 2012, Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity, Blood, 119, 3734, 10.1182/blood-2011-11-392951
Nomoto, 2015, A donor thrombomodulin gene variation predicts graft-versus-host disease development and mortality after bone marrow transplantation, International Journal of Hematology, 102, 460, 10.1007/s12185-015-1852-7
Norsworthy, 2004, Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis, Journal of Immunology, 172, 3406, 10.4049/jimmunol.172.6.3406
Noubade, 2019, Beyond cDC1: Emerging roles of DC crosstalk in cancer immunity, Frontiers in Immunology, 10, 10.3389/fimmu.2019.01014
O'Connell, 2019, SLAMF7 is a critical negative regulator of IFN-α–mediated CXCL10 production in chronic HIV infection, Journal of Immunology, 202, 228, 10.4049/jimmunol.1800847
Oh, 2020, PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer, Nat. Cancer, 1, 681, 10.1038/s43018-020-0075-x
Ohtsuka, 2011, Bcl6 is required for the development of mouse CD4 + and CD8α + dendritic cells, Journal of Immunology, 186, 255, 10.4049/jimmunol.0903714
Oosting, 2014, Human TLR10 is an anti-inflammatory pattern-recognition receptor, Proceedings of the National Academy of Sciences, 111, E4478, 10.1073/pnas.1410293111
Ou, 2019, Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells, The Journal of Experimental Medicine, 216, 2091, 10.1084/jem.20190041
Pan, 2017, G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin, Scientific Reports, 7, 692, 10.1038/s41598-017-00781-w
Pearson, 2020, Human CLEC9A antibodies deliver Wilms’ tumor 1 (WT1) antigen to CD141 + dendritic cells to activate naïve and memory WT1-specific CD8 + T cells, Clinical & Translational Immunology, 9, 10.1002/cti2.1141
Poulin, 2012, DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues, Blood, 119, 6052, 10.1182/blood-2012-01-406967
Querol Cano, 2019, Intracellular galectin-9 controls dendritic cell function by maintaining plasma membrane rigidity, iScience, 22, 240, 10.1016/j.isci.2019.11.019
Rezende, 2019, γδ T cell–secreted XCL1 mediates anti-CD3–induced oral tolerance, J. Immunol, 203, 2621, 10.4049/jimmunol.1900784
Rizzitelli, 2012, Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation, Immunology and Cell Biology, 90, 841, 10.1038/icb.2012.29
Rosa, 2018, Direct reprogramming of fibroblasts into antigen-presenting dendritic cells, Sci. Immunol, 3, 10.1126/sciimmunol.aau4292
Roselli, 2019, TLR3 activation of intratumoral CD103+ dendritic cells modifies the tumor infiltrate conferring anti-tumor immunity, Frontiers in Immunology, 10, 10.3389/fimmu.2019.00503
Ruhland, 2020, Visualizing synaptic transfer of tumor antigens among dendritic cells, Cancer Cell, 37, 786, 10.1016/j.ccell.2020.05.002
Saito, 2013, Dendritic cell homeostasis is maintained by nonhematopoietic and T-cell-produced Flt3-ligand in steady state and during immune responses, European Journal of Immunology, 10.1002/eji.201243163
Salmon, 2016, Expansion and activation of CD103 + dendritic cell progenitors at the tumor site enhances tumor responses to therapeutic PD-L1 and BRAF inhibition, Immunity, 44, 924, 10.1016/j.immuni.2016.03.012
Sancho, 2012, Signaling by myeloid C-type lectin receptors in immunity and homeostasis, Annu. Rev. Immunol, 30, 491, 10.1146/annurev-immunol-031210-101352
Saxena, 2018, Towards superior dendritic-cell vaccines for cancer therapy, Nature Biomedical Engineering, 2, 341, 10.1038/s41551-018-0250-x
Schreeder, 2010, Cutting edge: FcR-like 6 is an MHC class II receptor, Journal of Immunology, 185, 23, 10.4049/jimmunol.1000832
Schröder, 2016, The multifaceted roles of the invariant chain CD74 — More than just a chaperone, Biochim. Biophys. Acta - Mol. Cell Res., 1863, 1269, 10.1016/j.bbamcr.2016.03.026
Sedy, 2005, B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator, Nature Immunology, 6, 90, 10.1038/ni1144
See, 2017, Mapping the human DC lineage through the integration of high-dimensional techniques, Science, 356, 10.1126/science.aag3009
Segura, 2013, Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ–resident dendritic cells, The Journal of Experimental Medicine, 210, 1035, 10.1084/jem.20121103
Shao, 2020, Dipeptidyl peptidase 4 inhibitors and their potential immune modulatory functions, Pharmacology & Therapeutics, 209, 107503, 10.1016/j.pharmthera.2020.107503
Sharma, 2019, Role of AIM2 inflammasome in inflammatory diseases, cancer and infection, European Journal of Immunology, 49, 1998, 10.1002/eji.201848070
Shi, 2008, Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response, Blood, 112, 3661, 10.1182/blood-2008-03-142760
Shimizu, 2016, Systemic DC activation modulates the tumor microenvironment and shapes the long-lived tumor-specific memory mediated by CD8 + T cells, Cancer Research, 76, 3756, 10.1158/0008-5472.CAN-15-3219
Silvin, 2017, Constitutive resistance to viral infection in human CD141 + dendritic cells, Sci. Immunol, 2, 10.1126/sciimmunol.aai8071
Sittig, 2016, A comparative study of the T cell stimulatory and polarizing capacity of human primary blood dendritic cell subsets, Mediators of Inflammation, 2016, 1, 10.1155/2016/3605643
Soares, 2007, A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo, The Journal of Experimental Medicine, 204, 1095, 10.1084/jem.20070176
Sosinowski, 2013, CD8α + dendritic cell trans presentation of IL-15 to naive CD8 + T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function, Journal of Immunology, 190, 1936, 10.4049/jimmunol.1203149
Spranger, 2017, Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy, Cancer Cell, 31, 711, 10.1016/j.ccell.2017.04.003
Starzer, 2020, New emerging targets in cancer immunotherapy: CD27 (TNFRSF7), ESMO Open, 4, 10.1136/esmoopen-2019-000629
Stenmark, 2009, Rab GTPases as coordinators of vesicle traffic, Nature Reviews. Molecular Cell Biology, 10, 513, 10.1038/nrm2728
Takeuchi, 2009, CRTAM confers late-stage activation of CD8 + T cells to regulate retention within lymph node, Journal of Immunology, 183, 4220, 10.4049/jimmunol.0901248
Theisen, 2018, WDFY4 is required for cross-presentation in response to viral and tumor antigens, Science, 362, 694, 10.1126/science.aat5030
Theisen, 2019, Batf3-dependent genes control tumor rejection induced by dendritic cells independently of cross-presentation, Cancer Immunology Research, 7, 29, 10.1158/2326-6066.CIR-18-0138
Tokunaga, 2018, CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy, Cancer Treatment Reviews, 63, 40, 10.1016/j.ctrv.2017.11.007
Trad, 2015, T lymphocyte inhibition by tumor-infiltrating dendritic cells involves Ectonucleotidase CD39 but not Arginase-1, BioMed Research International, 2015, 1, 10.1155/2015/891236
Tussiwand, 2012, Compensatory dendritic cell development mediated by BATF–IRF interactions, Nature, 490, 502, 10.1038/nature11531
Utting, 2004, Immune functions in mice lacking Clnk, an SLP-76-related adaptor expressed in a subset of immune cells, Molecular and Cellular Biology, 24, 6067, 10.1128/MCB.24.13.6067-6075.2004
van der Aa, 2016, The effect of chronic hepatitis B virus infection on BDCA3+ dendritic cell frequency and function, PLoS One, 11, 10.1371/journal.pone.0161235
van der Weyden, 2012, Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1, Molecular Cancer, 11, 29, 10.1186/1476-4598-11-29
van Driel, 2016, Responses to microbial challenges by SLAMF receptors, Frontiers in Immunology, 7, 10.3389/fimmu.2016.00004
Vaughn, 2014, Purinergic signaling in liver disease, Digestive Diseases, 32, 516, 10.1159/000360498
Velazquez, 2012, Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection, Hepatology, 56, 2071, 10.1002/hep.25904
Villani, 2017, Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors, Science (80), 356
Wakim, 2011, Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection, Nature, 471, 629, 10.1038/nature09863
Wang, 2019, Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses, Proc. Natl. Acad. Sci., 116, 9511, 10.1073/pnas.1901258116
Watchmaker, 2014, Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice, Nature Immunology, 15, 98, 10.1038/ni.2768
Wculek, 2020, Dendritic cells in cancer immunology and immunotherapy, Nature Reviews. Immunology, 20, 7, 10.1038/s41577-019-0210-z
Weimershaus, 2012, Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation, Journal of Immunology, 188, 1840, 10.4049/jimmunol.1101504
Wilson, 2007, FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection, Blood, 109, 3786, 10.1182/blood-2006-06-030023
Wong, 2013, IL-18-primed helper NK cells collaborate with dendritic cells to promote recruitment of effector CD8+ T cells to the tumor microenvironment, Cancer Research, 73, 4653, 10.1158/0008-5472.CAN-12-4366
Yang, 2014, A BTLA-mediated bait and switch strategy permits Listeria expansion in CD8α+ DCs to promote long-term T cell responses, Cell Host & Microbe, 16, 68, 10.1016/j.chom.2014.05.021
Yerkovich, 2009, Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response, J. Allergy Clin. Immunol, 123, 209, 10.1016/j.jaci.2008.09.009
Yu, 2001, Synergistic regulation of Immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1, Molecular and Cellular Biology, 21, 6102, 10.1128/MCB.21.18.6102-6112.2001
Yu, 2014, Human CD141 + dendritic cells induce CD4 + T cells to produce type 2 cytokines, Journal of Immunology, 193, 4335, 10.4049/jimmunol.1401159
Zanoni, 2017, Interferon (IFN)-λ takes the helm: Immunomodulatory roles of type III IFNs, Frontiers in Immunology, 8, 10.3389/fimmu.2017.01661
Zelenay, 2012, The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice, The Journal of Clinical Investigation, 122, 1615, 10.1172/JCI60644
Zeng, 2018, Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy, The Journal of Clinical Investigation, 128, 1971, 10.1172/JCI96791
Zhang, 2013, Human Type 2 myeloid dendritic cells produce interferon-λ and amplify interferon-α in response to hepatitis C virus infection, Gastroenterology, 144, 414, 10.1053/j.gastro.2012.10.034
