Ultraviolet light and ocular diseases

Jason C. Yam1, Anthony Kwok2
1Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, 4/F, Hong Kong Eye Hospital, 147 K Argyle Street, Kowloon, Hong Kong, People’s Republic of China
2Department of Ophthalmology, Hong Kong Sanatorium and Hospital, Hong Kong, People’s Republic of China

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Tài liệu tham khảo

McKenzie RL, Bjorn LO, Bais A, Ilyasad M (2003) Changes in biologically active ultraviolet radiation reaching the Earth’s surface. Photochem Photobiol Sci 2(1):5–15

World Health Organization (2002) Global solar UV index: a practical guide. World Health Organization, Geneva

McCarty CA, Taylor HR (2002) A review of the epidemiologic evidence linking ultraviolet radiation and cataracts. Dev Ophthalmol 35:21–31

Young S, Sands J (1998) Sun and the eye: prevention and detection of light-induced disease. Clin Dermatol 16(4):477–485

Tse TG, Gilberg SM (1997) Malignant eyelid tumours. In: Krachmer JH, Mannis MJ, Holland EJ (eds) Cornea, vol II. Mosby, St. Louis, pp 601–605

Rigel DS (2008) Cutaneous ultraviolet exposure and its relationship to the development of skin cancer. J Am Acad Dermatol 58(5 Suppl 2):S129–S132

Gallagher RP, Hill GB, Bajdik CD, Coldman AJ, Fincham S, McLean DI et al (1995) Sunlight exposure, pigmentation factors, and risk of nonmelanocytic skin cancer. II. Squamous cell carcinoma. Arch Dermatol 131(2):164–169

Rosso S, Zanetti R, Martinez C, Tormo MJ, Schraub S, Sancho-Garnier H et al (1996) The multicentre south European study ‘Helios’. II: different sun exposure patterns in the aetiology of basal cell and squamous cell carcinomas of the skin. Br J Cancer 73(11):1447–1454

Strickland PT, Vitasa BC, West SK, Rosenthal FS, Emmett EA, Taylor HR (1989) Quantitative carcinogenesis in man: solar ultraviolet B dose dependence of skin cancer in Maryland watermen. J Natl Cancer Inst 81(24):1910–1913

Kricker A, Armstrong BK, English DR, Heenan PJ (1995) Does intermittent sun exposure cause basal cell carcinoma? A case–control study in Western Australia. Int J Cancer 60(4):489–494

Gallagher RP, Hill GB, Bajdik CD, Fincham S, Coldman AJ, McLean DI et al (1995) Sunlight exposure, pigmentary factors, and risk of nonmelanocytic skin cancer. I. Basal cell carcinoma. Arch Dermatol 131(2):157–163

Naldi L, DiLandro A, D’Avanzo B, Parazzini F (2000) Host-related and environmental risk factors for cutaneous basal cell carcinoma: evidence from an Italian case–control study. J Am Acad Dermatol 42(3):446–452

Corona R, Dogliotti E, D’Errico M, Sera F, Iavarone I, Baliva G et al (2001) Risk factors for basal cell carcinoma in a Mediterranean population: role of recreational sun exposure early in life. Arch Dermatol 137(9):1162–1168

Meeran SM, Punathil T, Katiyar SK (2008) IL-12 deficiency exacerbates inflammatory responses in UV-irradiated skin and skin tumors. J Invest Dermatol 128(11):2716–2727

Benjamin CL, Ananthaswamy HN (2007) p53 and the pathogenesis of skin cancer. Toxicol Appl Pharmacol 224(3):241–248

Ouhtit A, Nakazawa H, Armstrong BK, Kricker A, Tan E, Yamasaki H et al (1998) UV-radiation-specific p53 mutation frequency in normal skin as a predictor of risk of basal cell carcinoma. J Natl Cancer Inst 90(7):523–531

Vainio H, Miller AB, Bianchini F (2000) An international evaluation of the cancer-preventive potential of sunscreens. Int J Cancer 88(5):838–842

Cameron M (1965) Pterygium throughout the world. Charles C. Thomas, Springfield

Mackenzie FD, Hirst LW, Battistutta D, Green A (1992) Risk analysis in the development of pterygia. Ophthalmology 99(7):1056–1061

Moran DJ, Hollows FC (1984) Pterygium and ultraviolet radiation: a positive correlation. Br J Ophthalmol 68(5):343–346

Taylor HR, West SK, Rosenthal FS, Munoz B, Newland HS, Emmett EA (1989) Corneal changes associated with chronic UV irradiation. Arch Ophthalmol 107(10):1481–1484

Norn MS (1982) Spheroid degeneration, pinguecula, and pterygium among Arabs in the Red Sea territory, Jordan. Acta Ophthalmol (Copenh) 60(6):949–954

Austin P, Jakobiec FA, Iwamoto T (1983) Elastodysplasia and elastodystrophy as the pathologic bases of ocular pterygia and pinguecula. Ophthalmology 90(1):96–109

Coroneo M (2011) Ultraviolet radiation and the anterior eye. Eye Contact Lens 37(4):214–224

Chui J, Di Girolamo N, Wakefield D, Coroneo MT (2008) The pathogenesis of pterygium: current concepts and their therapeutic implications. Ocul Surf 6(1):24–43

Nolan TM, DiGirolamo N, Sachdev NH, Hampartzoumian T, Coroneo MT, Wakefield D (2003) The role of ultraviolet irradiation and heparin-binding epidermal growth factor-like growth factor in the pathogenesis of pterygium. Am J Pathol 162(2):567–574

Yang SF, Lin CY, Yang PY, Chao SC, Ye YZ, Hu DN (2009) Increased expression of gelatinase (MMP-2 and MMP-9) in pterygia and pterygium fibroblasts with disease progression and activation of protein kinase C. Invest Ophthalmol Vis Sci 50(10):4588–4596

Coroneo MT, Muller-Stolzenburg NW, Ho A (1991) Peripheral light focusing by the anterior eye and the ophthalmohelioses. Ophthalmic Surg 22(12):705–711

Hoffman RS, Power WJ (1999) Current options in pterygium management. Int Ophthalmol Clin 39(1):15–26

Cullen AP (2002) Photokeratitis and other phototoxic effects on the cornea and conjunctiva. Int J Toxicol 21(6):455–464

Ren H, Wilson G (1994) The effect of ultraviolet-B irradiation on the cell shedding rate of the corneal epithelium. Acta Ophthalmol (Copenh) 72(4):447–452

Podskochy A, Gan L, Fagerholm P (2000) Apoptosis in UV-exposed rabbit corneas. Cornea 19(1):99–103

Oliva MS, Taylor H (2005) Ultraviolet radiation and the eye. Int Ophthalmol Clin 45(1):1–17

Gray RH, Johnson GJ, Freedman A (1992) Climatic droplet keratopathy. Surv Ophthalmol 36(4):241–253

Klintworth GK (1972) Chronic actinic keratopathy—a condition associated with conjunctival elastosis (pingueculae) and typified by characteristic extracellular concretions. Am J Pathol 67(2):327–348

Johnson GJ (1981) Aetiology of spheroidal degeneration of the cornea in Labrador. Br J Ophthalmol 65(4):270–283

Pe’er J (2005) Ocular surface squamous neoplasia. Ophthalmol Clin North Am 18(1):1–13, vii

Templeton AC (1967) Tumors of the eye and adnexa in Africans of Uganda. Cancer 20(10):1689–1698

Malik MO, El Sheikh EH (1979) Tumors of the eye and adnexa in the Sudan. Cancer 44(1):293–303

Sun EC, Fears TR, Goedert JJ (1997) Epidemiology of squamous cell conjunctival cancer. Cancer Epidemiol Biomarkers Prev 6(2):73–77

Pola EC, Masanganise R, Rusakaniko S (2003) The trend of ocular surface squamous neoplasia among ocular surface tumour biopsies submitted for histology from Sekuru Kaguvi Eye Unit, Harare between 1996 and 2000. Cent Afr J Med 49(1–2):1–4

Lee GA, Hirst LW (1992) Incidence of ocular surface epithelial dysplasia in metropolitan Brisbane. A 10-year survey. Arch Ophthalmol 110(4):525–527

Newton R, Ferlay J, Reeves G, Beral V, Parkin DM (1996) Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye. Lancet 347(9013):1450–1451

Lee GA, Williams G, Hirst LW, Green AC (1994) Risk factors in the development of ocular surface epithelial dysplasia. Ophthalmology 101(2):360–364

Lee GA, Hirst LW (1995) Ocular surface squamous neoplasia. Surv Ophthalmol 39(6):429–450

Hiller R, Giacometti L, Yuen K (1977) Sunlight and cataract: an epidemiologic investigation. Am J Epidemiol 105(5):450–459

Taylor HR (1980) The environment and the lens. Br J Ophthalmol 64(5):303–310

Hollows F, Moran D (1981) Cataract—the ultraviolet risk factor. Lancet 2(8258):1249–1250

Chatterjee A, Milton RC, Thyle S (1982) Prevalence and aetiology of cataract in Punjab. Br J Ophthalmol 66(1):35–42

Brilliant LB, Grasset NC, Pokhrel RP, Kolstad A, Lepkowski JM, Brilliant GE et al (1983) Associations among cataract prevalence, sunlight hours, and altitude in the Himalayas. Am J Epidemiol 118(2):250–264

Wojno T, Singer D, Schultz RO (1983) Ultraviolet light, cataracts, and spectacle wear. Ann Ophthalmol 15(8):729–732

Perkins ES (1985) The association between pinguecula, sunlight and cataract. Ophthalmic Res 17(6):325–330

Collman GW, Shore DL, Shy CM, Checkoway H, Luria AS (1988) Sunlight and other risk factors for cataracts: an epidemiologic study. Am J Public Health 78(11):1459–1462

Taylor HR, West SK, Rosenthal FS, Munoz B, Newland HS, Abbey H et al (1988) Effect of ultraviolet radiation on cataract formation. N Engl J Med 319(22):1429–1433

Dolezal JM, Perkins ES, Wallace RB (1989) Sunlight, skin sensitivity, and senile cataract. Am J Epidemiol 129(3):559–568

Bochow TW, West SK, Azar A, Munoz B, Sommer A, Taylor HR (1989) Ultraviolet light exposure and risk of posterior subcapsular cataracts. Arch Ophthalmol 107(3):369–372

Mohan M, Sperduto RD, Angra SK, Milton RC, Mathur RL, Underwood BA et al (1989) India–US case–control study of age-related cataracts India–US Case–Control Study Group. Arch Ophthalmol 107(5):670–676

Leske MC, Chylack LT Jr, Wu SY (1991) The Lens Opacities Case–Control Study. Risk factors for cataract. Arch Ophthalmol 109(2):244–251

Cruickshanks KJ, Klein BE, Klein R (1992) Ultraviolet light exposure and lens opacities: the Beaver Dam Eye Study. Am J Public Health 82(12):1658–1662

Wong L, Ho SC, Coggon D, Cruddas AM, Hwang CH, Ho CP et al (1993) Sunlight exposure, antioxidant status, and cataract in Hong Kong fishermen. J Epidemiol Community Health 47(1):46–49

Rosmini F, Stazi MA, Milton RC, Sperduto RD, Pasquini P, Maraini G (1994) A dose–response effect between a sunlight index and age-related cataracts. Italian-American Cataract Study Group. Ann Epidemiol 4(4):266–270

Hirvela H, Luukinen H, Laatikainen L (1995) Prevalence and risk factors of lens opacities in the elderly in Finland. A population-based study. Ophthalmology 102(1):108–117

Javitt JC, Taylor HR (1994) Cataract and latitude. Doc Ophthalmol 88(3–4):307–325

Burton M, Fergusson E, Hart A, Knight K, Lary D, Liu C (1997) The prevalence of cataract in two villages of northern Pakistan with different levels of ultraviolet radiation. Eye (Lond) 11(Pt 1):95–101

West SK, Duncan DD, Munoz B, Rubin GS, Fried LP, Bandeen-Roche K et al (1998) Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation project. J Am Med Assoc 280(8):714–718

McCarty CA, Nanjan MB, Taylor HR (2000) Attributable risk estimates for cataract to prioritize medical and public health action. Invest Ophthalmol Vis Sci 41(12):3720–3725

Delcourt C, Carriere I, Ponton-Sanchez A, Lacroux A, Covacho MJ, Papoz L (2000) Light exposure and the risk of cortical, nuclear, and posterior subcapsular cataracts: the Pathologies Oculaires Liees a l’Age (POLA) study. Arch Ophthalmol 118(3):385–392

Katoh N, Jonasson F, Sasaki H, Kojima M, Ono M, Takahashi N et al (2001) Cortical lens opacification in Iceland. Risk factor analysis—Reykjavik Eye Study. Acta Ophthalmol Scand 79(2):154–159

Neale RE, Purdie JL, Hirst LW, Green AC (2003) Sun exposure as a risk factor for nuclear cataract. Epidemiology 14(6):707–712

Pastor-Valero M, Fletcher AE, de Stavola BL, Chaques-Alepuz V (2007) Years of sunlight exposure and cataract: a case–control study in a Mediterranean population. BMC Ophthalmol 7:18

Bergmanson JP, Soderberg PG (1995) The significance of ultraviolet radiation for eye diseases. A review with comments on the efficacy of UV-blocking contact lenses. Ophthalmic Physiol Opt 15(2):83–91

Cruickshanks KJ, Klein R, Klein BE (1993) Sunlight and age-related macular degeneration. The Beaver Dam Eye Study. Arch Ophthalmol 111(4):514–518

Roduit R, Schorderet DF (2008) MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells. Apoptosis 13(3):343–353

Youn BHCAP, Chou BR, Sivak JG (2010) Phototoxicity of ultraviolet (UV) radiation: evaluation of UV-blocking efficiency of intraocular lens (IOL) materials using retinal cell culture and in vitro. Open Toxicol J 4:13–20

Chalam KV, Khetpal V, Rusovici R, Balaiya S (2011) A review: role of ultraviolet radiation in age-related macular degeneration. Eye Contact Lens 37(4):225–232

Hyman LG, Lilienfeld AM, Ferris FL 3rd, Fine SL (1983) Senile macular degeneration: a case–control study. Am J Epidemiol 118(2):213–227

West SK, Rosenthal FS, Bressler NM, Bressler SB, Munoz B, Fine SL et al (1989) Exposure to sunlight and other risk factors for age-related macular degeneration. Arch Ophthalmol 107(6):875–879

Taylor HR, West S, Munoz B, Rosenthal FS, Bressler SB, Bressler NM (1992) The long-term effects of visible light on the eye. Arch Ophthalmol 110(1):99–104

Risk factors for neovascular age-related macular degeneration. The Eye Disease Case–Control Study Group. Arch Ophthalmol 1992 110(12):1701–1708

Darzins P, Mitchell P, Heller RF (1997) Sun exposure and age-related macular degeneration. An Australian case–control study. Ophthalmology 104(5):770–776

Delcourt C, Carriere I, Ponton-Sanchez A, Fourrey S, Lacroux A, Papoz L (2001) Light exposure and the risk of age-related macular degeneration: the Pathologies Oculaires Liees a l’Age (POLA) study. Arch Ophthalmol 119(10):1463–1468

McCarty CA, Mukesh BN, Fu CL, Mitchell P, Wang JJ, Taylor HR (2001) Risk factors for age-related maculopathy: the Visual Impairment Project. Arch Ophthalmol 119(10):1455–1462

Khan JC, Shahid H, Thurlby DA, Bradley M, Clayton DG, Moore AT et al (2006) Age related macular degeneration and sun exposure, iris colour, and skin sensitivity to sunlight. Br J Ophthalmol 90(1):29–32

Sui GY, Liu GC, Liu GY, Gao YY, Deng Y, Wang WY et al (2013) Is sunlight exposure a risk factor for age-related macular degeneration? A systematic review and meta-analysis. Br J Ophthalmol 97(4):389–394

Wang JJ, Klein R, Smith W, Klein BE, Tomany S, Mitchell P (2003) Cataract surgery and the 5-year incidence of late-stage age-related maculopathy: pooled findings from the Beaver Dam and Blue Mountains eye studies. Ophthalmology 110(10):1960–1967

Sparrow JR, Miller AS, Zhou J (2004) Blue light-absorbing intraocular lens and retinal pigment epithelium protection in vitro. J Cataract Refract Surg 30(4):873–878

Iu LP, Kwok AK (2007) An update of treatment options for neovascular age-related macular degeneration. Hong Kong Med J 13(6):460–470

Ajani UA, Seddon JM, Hsieh CC, Egan KM, Albert DM, Gragoudas ES (1992) Occupation and risk of uveal melanoma. An exploratory study. Cancer 70(12):2891–2900

Damato B (2004) Developments in the management of uveal melanoma. Clin Exp Ophthalmol 32(6):639–647

Jhappan C, Noonan FP, Merlino G (2003) Ultraviolet radiation and cutaneous malignant melanoma. Oncogene 22(20):3099–3112

Shah CP, Weis E, Lajous M, Shields JA, Shields CL (2005) Intermittent and chronic ultraviolet light exposure and uveal melanoma: a meta-analysis. Ophthalmology 112(9):1599–1607

Gallagher RP, Elwood JM, Rootman J, Spinelli JJ, Hill GB, Threlfall WJ et al (1985) Risk factors for ocular melanoma: Western Canada Melanoma Study. J Natl Cancer Inst 74(4):775–778

Tucker MA, Shields JA, Hartge P, Augsburger J, Hoover RN, Fraumeni JF Jr (1985) Sunlight exposure as risk factor for intraocular malignant melanoma. N Engl J Med 313(13):789–792

Seddon JM, Gragoudas ES, Glynn RJ, Egan KM, Albert DM, Blitzer PH (1990) Host factors, UV radiation, and risk of uveal melanoma. A case–control study. Arch Ophthalmol 108(9):1274–1280

Holly EA, Aston DA, Char DH, Kristiansen JJ, Ahn DK (1990) Uveal melanoma in relation to ultraviolet light exposure and host factors. Cancer Res 50(18):5773–5777

Holly EA, Aston DA, Ahn DK, Smith AH (1996) Intraocular melanoma linked to occupations and chemical exposures. Epidemiology 7(1):55–61

Pane AR, Hirst LW (2000) Ultraviolet light exposure as a risk factor for ocular melanoma in Queensland, Australia. Ophthalmic Epidemiol 7(3):159–167

Guenel P, Laforest L, Cyr D, Fevotte J, Sabroe S, Dufour C et al (2001) Occupational risk factors, ultraviolet radiation, and ocular melanoma: a case–control study in France. Cancer Causes Control 12(5):451–459

Vajdic CM, Kricker A, Giblin M, McKenzie J, Aitken J, Giles GG et al (2002) Sun exposure predicts risk of ocular melanoma in Australia. Int J Cancer 101(2):175–182

Lutz JM, Cree I, Sabroe S, Kvist TK, Clausen LB, Afonso N et al (2005) Occupational risks for uveal melanoma results from a case–control study in nine European countries. Cancer Causes Control 16(4):437–447

Bergmanson JP, Sheldon TM (1997) Ultraviolet radiation revisited. CLAO J 23(3):196–204