Ultrasound Evaluation of Site-Specific Effect of Simulated Microgravity on Articular Cartilage

Allen, 2003, Hindlimb unloading has a greater effect on cortical compared with cancellous bone in mature female rats, J Appl Physiol, 94, 642, 10.1152/japplphysiol.00656.2002 Arokoski, 2000, Normal and pathological adaptations of articular cartilage to joint loading, Scand J Med Sci Sports, 10, 186, 10.1034/j.1600-0838.2000.010004186.x Basso, 2006, Effects of hind limb unloading and reloading on nitric oxide synthase expression and apoptosis of osteocytes and chondrocytes, Bone, 39, 807, 10.1016/j.bone.2006.04.014 Booth, 1994, Comparison of the physiology of the spaceflight and hindlimb suspended rat, 275 Brommer, 2005, Functional adaptation of articular cartilage from birth to maturity under the influence of loading: a biomechanical analysis, Equine Vet J, 37, 148, 10.2746/0425164054223769 Buschmann, 1999, Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow, Arch Biochem Biophys, 366, 1, 10.1006/abbi.1999.1197 Cherin, 1998, Evaluation of acoustical parameter sensitivity to age-related and osteoarthritic changes in articular cartilage using 50-MHz ultrasound, Ultrasound Med Biol, 24, 341, 10.1016/S0301-5629(97)00289-5 Duke, 1999, Exposure to altered gravity affects all stages of endochondral cartilage differentiation, Adv Space Res, 24, 821, 10.1016/S0273-1177(99)00077-0 Fincke, 2005, Evaluation of shoulder integrity in space: first report of musculoskeletal US on the International Space Station, Radiology, 234, 319, 10.1148/radiol.2342041680 Foster, 2000, Advances in ultrasound biomicroscopy, Ultrasound Med Biol, 26, 1, 10.1016/S0301-5629(99)00096-4 Gardner, 1971, Living articular cartilage is not smooth: The structure of mammalian and avian joint surfaces demonstrated in vivo by immersion incident light microscopy, Ann Rheum Dis, 30, 3, 10.1136/ard.30.1.3 Globus, 1986, The temporal response of bone to unloading, Endocrinology, 118, 733, 10.1210/endo-118-2-733 Guo, 2008, Acceleration of bone decalcification by ultrasound, 201 Hargens, 1984, Tissue fluid shift, forelimb loading, and tail tension in tailsuspended rats, Physiologist, 27, S37 Hargens, 1996, Cardiovascular adaptation to spaceflight, Med Sci Sports Exerc, 28, 977, 10.1097/00005768-199608000-00007 Huang, 2007, Reliability of measurement of skin ultrasonic properties in vivo: A potential technique for assessing irradiated skin, Skin Res Technol, 13, 55, 10.1111/j.1600-0846.2006.00191.x Hutton, 2002, Effect of tail suspension (or simulated weightlessness) on the lumbar intervertebral disc: Study of proteoglycans and collagen, Spine, 27, 1286, 10.1097/00007632-200206150-00008 Hattori, 2005, Quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritis, Arthritis Res Ther, 7, R38, 10.1186/ar1463 Joiner, 2001, High frequency acoustic parameters of human and bovine articular cartilage following experimentally-induced matrix degradation, Ultrasonic Imaging, 23, 106, 10.1177/016173460102300203 Jortikka, 1997, Immobilisation causes longlasting matrix changes both in the immobilised and contralateral joint cartilage, Ann Rheum Dis, 56, 255, 10.1136/ard.56.4.255 Jurvelin, 1995, Comparison of optical, needle probe and ultrasonic techniques for measurement of articular cartilage thickness, J Biomech, 28, 231, 10.1016/0021-9290(94)00060-H Kodama, 1997, Inhibition of bone resorption by pamidronate cannot restore normal gain in cortical bone mass and strength in tail-suspended rapidly growing rats, J Bone Miner Res, 12, 1058, 10.1359/jbmr.1997.12.7.1058 Laasanen, 2005, Site-specific ultrasound reflection properties and superficial collagen content of bovine knee articular cartilage, Phys Med Biol, 50, 3221, 10.1088/0031-9155/50/14/002 Lam, 2008, The effects of frequency-dependent dynamic muscle stimulation on inhibition of trabecular bone loss in a disuse model, Bone, 43, 1093, 10.1016/j.bone.2008.07.253 Leroux, 2001, Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization, Osteoarthritis Cartilage, 9, 633, 10.1053/joca.2001.0432 Lippiello, 1985, In vitro metabolic response of articular cartilage segments to low levels of hydrostatic pressure, Connect Tissue Res, 13, 99, 10.3109/03008208509152388 Montufar-Solis, 1996, In vivo and in vitro studies of cartilage differentiation in altered gravities, Adv Space Res, 17, 193, 10.1016/0273-1177(95)00635-R Morey-Holton, 1979, Spaceflight and bone turnover: Correlation with a new rat model of weightlessness, Bioscience, 29, 168, 10.2307/1307797 Morey-Holton, 2002, Hindlimb unloading rodent model: Technical aspects, J Appl Physiol, 92, 1367, 10.1152/japplphysiol.00969.2001 Moriyama, 2008, Alteration in articular cartilage of rat knee joints after spinal cord injury, Osteoarthritis Cartilage, 16, 392, 10.1016/j.joca.2007.07.002 Mow, 2005, Structure and function of articular cartilage and meniscus, 181 Mow, 2001, Biomechanics of articular cartilage, 60 Naish, 2003, Ultrasound imaging of the intervertebral disc, Spine, 28, 107, 10.1097/00007632-200301150-00003 Nieminen, 2002, Real-time ultrasound analysis of articular cartilage degradation in vitro, Ultrasound Med Biol, 28, 519, 10.1016/S0301-5629(02)00480-5 O'Connor, 1997, Unweighting accelerates tidemark advancement in articular cartilage at the knee joint of rats, J Bone Miner Res, 12, 580, 10.1359/jbmr.1997.12.4.580 Ostergaard, 1997, Histologic/histochemical grading system for osteoarthritic articular cartilage: reproducibility and validity, Arthritis Rheum, 40, 1766, 10.1002/art.1780401007 Payne, 2007, Space flight rehabilitation, Am J Phys Med Rehabil, 86, 583, 10.1097/PHM.0b013e31802b8d09 Saarakkala, 2004, Ultrasonic quantitation of superficial degradation of articular cartilage, Ultrasound Med Biol, 30, 783, 10.1016/j.ultrasmedbio.2004.03.005 Saarakkala, 2006, Quantitative ultrasound imaging detects degenerative changes in articular cartilage surface and subchondral bone, Phys Med Biol, 51, 5333, 10.1088/0031-9155/51/20/017 Saijo, 2000, Microscopy, Ultrasound Med Biol, 26, S30, 10.1016/S0301-5629(00)00157-5 Sakata, 1999, Trabecular bone turnover and bone marrow cell development in tail-suspended mice, J Bone Miner Res, 14, 1596, 10.1359/jbmr.1999.14.9.1596 Skribek, 2008, Role of ultrasound biomicroscopy in diagnosis and treatment of Terrien disease, Cornea, 27, 427, 10.1097/ICO.0b013e3181656460 Smith, 2002, Calcium and bone metabolism during space flight, Nutrition, 18, 849, 10.1016/S0899-9007(02)00895-X Spriet, 2005, Validation of a 40 MHz B-scan ultrasound biomicroscope for the evaluation of osteoarthritis lesions in an animal model, Osteoarthritis Cartilage, 13, 171, 10.1016/j.joca.2004.10.022 Tischler, 1993, Spaceflight on STS-48 and earthbased unweighting produce similar effects on skeletal muscle of young rats, J Appl Physiol, 74, 2161, 10.1152/jappl.1993.74.5.2161 Toyras, 1999, Characterization of enzymatically induced degradation of articular cartilage using high frequency ultrasound, Phys Med Biol, 44, 2723, 10.1088/0031-9155/44/11/303 Vico, 2000, Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts, Lancet, 355, 1607, 10.1016/S0140-6736(00)02217-0 Wang, 2006, Non-contact evaluation of osmosis-induced shrinkage and swelling behavior of articular cartilage in situ using high-frequency ultrasound, Instrument Sci Technol, 34, 317, 10.1080/1073914600609433 Wang, 2008, Real-time ultrasonic assessment of progressive proteoglycan depletion in articular cartilage, Ultrasound Med Biol, 34, 1085, 10.1016/j.ultrasmedbio.2007.12.006 Wang, 2008, Altered osmotic swelling behavior of proteoglycan-depleted bovine articular cartilage using high frequency ultrasound, Phys Med Biol, 53, 2537, 10.1088/0031-9155/53/10/006 Wang, 2009, Ultrasound biomicroscopy imaging for monitoring progressive trypsin digestion and inhibition in articular cartilage, Ultrasound Med Biol, 35, 1535, 10.1016/j.ultrasmedbio.2009.04.011 White, 2001, Humans in space, Nature, 409, 1115, 10.1038/35059243 Williams, 2009, Acclimation during space flight: Effects on human physiology, CMAJ, 180, 1317, 10.1503/cmaj.090628 Yasuoka, 2007, Effects of reloading after simulated microgravity on proteoglycan metabolism in the nucleus pulposus and anulus fibrosus of the lumbar intervertebral disc: An experimental study using a rat tail suspension model, Spine, 32, E734, 10.1097/BRS.0b013e31815b7e51 Yoshida, 2006, Three-dimensional dynamic hip contact area and pressure distribution during activities of daily living, J Biomech, 39, 1996, 10.1016/j.jbiomech.2005.06.026 Zheng, 2004, Dynamic depth-dependent osmotic swelling and solute diffusion in articular cartilage monitored using real-time ultrasound, Ultrasound Med Biol, 30, 841, 10.1016/j.ultrasmedbio.2004.02.009