UVB suppresses PTEN expression by upregulating miR-141 in HaCaT cells

Marrot, 2008, Skin DNA photodamage and its biological consequences, J Am Acad Dermatol, 58, S139, 10.1016/j.jaad.2007.12.007 Timares, 2008, DNA damage, apoptosis and langerhans cells–Activators of UV-induced immune tolerance, Photochem Photobiol, 84, 422, 10.1111/j.1751-1097.2007.00284.x Heck, 2004, Solar ultraviolet radiation as a trigger of cell signal transduction, Toxicol Appl Pharmacol, 195, 288, 10.1016/j.taap.2003.09.028 Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5 Croce, 2005, miRNAs, cancer, and stem cell division, Cell, 122, 6, 10.1016/j.cell.2005.06.036 Guo, 2009, Differential Expression Profiles of microRNAs in NIH3T3 Cells in Response to UVB Irradiation. Photochem Photobiol, May-Jun, 85, 765 Pothof, 2009, MicroRNA responses and stress granule formation modulate the DNA damage response, Cell Cycle, 8, 3462, 10.4161/cc.8.21.9835 Pothof, 2009, MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response, EMBO J, 28, 2090, 10.1038/emboj.2009.156 Zhang, 2011, The ATM Kinase Induces MicroRNA Biogenesis in the DNA Damage Response, Mol Cell, 41, 371, 10.1016/j.molcel.2011.01.020 Vrba, 2010, Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells, PLoS One, 5, e8697, 10.1371/journal.pone.0008697 Neves, 2010, Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells, BMC Res Notes, 3, 219, 10.1186/1756-0500-3-219 Zhang, 2010, microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network, Carcinogenesis, 31, 559, 10.1093/carcin/bgp335 Baffa, 2009, MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets, J Pathol, 219, 214, 10.1002/path.2586 Sorensen, 2010, Discovery of prostate cancer biomarkers by microarray gene expression profiling, Expert Rev Mol Diagn, 10, 49, 10.1586/erm.09.74 Zhang, 2010, microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network, Carcinogenesis, 31, 559, 10.1093/carcin/bgp335 He, 2006, Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance, Oncogene, 25, 3680, 10.1038/sj.onc.1209384 Ming, 2010, UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes, Oncogene, 29, 492, 10.1038/onc.2009.357 Soehnge, 1997, Mechanisms of induction of skin cancer by UV radiation, Front Biosci, 2, d538, 10.2741/A211 Yoshikawa, 1990, Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans, J Invest Dermatol, 95, 530, 10.1111/1523-1747.ep12504877 Lee, 2005, UVB phototherapy and skin cancer risk: a review of the literature, Int J Dermatol, 44, 355, 10.1111/j.1365-4632.2004.02186.x Kaina, 2003, DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling, Biochem Pharmacol, 66, 1547, 10.1016/S0006-2952(03)00510-0 Narasimhaiah, 2005, Oxidative damage and defective DNA repair is linked to apoptosis of migrating neurons and progenitors during cerebral cortex development in Ku70-deficient mice, Cereb Cortex, 15, 696, 10.1093/cercor/bhh171 Guan, 2010, Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding, Structure, 18, 1191, 10.1016/j.str.2010.06.016 Esteva, 2010, PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer, Am J Pathol, 177, 1647, 10.2353/ajpath.2010.090885 Sun, 2007, The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN, Mol Cancer Ther, 6, 2477, 10.1158/1535-7163.MCT-07-0186 Carnero, 2008, The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications, Curr Cancer Drug Targets, 8, 187, 10.2174/156800908784293659 Yu, 2009, PTEN regulation by Akt-EGR1-ARF-PTEN axis, EMBO J, 28, 21, 10.1038/emboj.2008.238 Pappas, 2007, Adenoviral-mediated PTEN expression radiosensitizes non-small cell lung cancer cells by suppressing DNA repair capacity, Cancer Gene Ther, 14, 543, 10.1038/sj.cgt.7701050 Cinti, 2008, Activated Akt as an indicator of prognosis in gastric cancer, Virchows Arch, 453, 449, 10.1007/s00428-008-0676-8 Palomero, 2008, The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia, Cell Cycle, 7, 965, 10.4161/cc.7.8.5753 Oh, 2006, Ultraviolet B-induced matrix metalloproteinase-1 and -3 secretions are mediated via PTEN/Akt pathway in human dermal fibroblasts, J Cell Physiol, 209, 775, 10.1002/jcp.20754