Hướng dẫn lâm sàng của Vương quốc Anh về phòng ngừa và điều trị loãng xương

Celia L Gregson1, David Armstrong2, Jean Bowden1, Cyrus Cooper3, John Edwards4, Neil Gittoes5, Nicholas C. Harvey3, John А. Kanis6, Sarah Leyland7, Rebecca Low8, Eugène McCloskey9, Katie Moss10, Jane Parker1, Zoë Paskins11, Kenneth Poole12,13, David M. Reid14, Mike Stone15, Julia Thomson7, Nic Vine1, Juliet Compston16
1Musculoskeletal Research Unit, Bristol Medical School, Learning and Research Building, University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK
2Western Health and Social Care Trust (NI), Nutrition Innovation Centre for Food and Health, Ulster University, and Visiting Professor, Belfast, Northern Ireland
3MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK
4Primary Care Centre Versus Arthritis, School of Medicine, Keele University, Staffordshire, and Wolstanton Medical Centre, Newcastle under Lyme, UK
5Centre for Endocrinology, Diabetes and Metabolism, Queen Elizabeth Hospital, University Hospitals Birmingham & University of Birmingham, Birmingham, UK
6Mary McKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia and Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK
7Royal Osteoporosis Society, Bath, UK
8Abingdon and Specialty Doctor in Metabolic Bone Disease, Marcham Road Health Centre, Nuffield Orthopaedic Centre, Oxford, UK
9Department of Oncology & Metabolism, MRC Versus Arthritis Centre for Integrated Research in Musculoskeletal Ageing (CIMA), Mellanby Centre for Musculoskeletal Research, University of Sheffield, Sheffield, UK
10St George’s University Hospital, London, UK
11School of Medicine, Keele University, Keele, Haywood Academic Rheumatology Centre, Haywood Hospital, Midlands Partnership NHS Foundation Trust, Stoke-on-Trent, UK
12NIHR Cambridge Biomedical Research Centre, Cambridge, UK
13Department of Medicine, University of Cambridge, Cambridge, UK
14University of Aberdeen, Aberdeen, Scotland
15University Hospital Llandough, Cardiff and Vale University Health Board, Llandough, UK
16University of Cambridge School of Clinical Medicine, Cambridge, UK

Tóm tắt

Tóm tắt Tóm tắt

Nhóm Hướng dẫn Loãng xương Quốc gia (NOGG) đã sửa đổi hướng dẫn của Vương quốc Anh về việc đánh giá và quản lý loãng xương cũng như phòng ngừa gãy xương do yếu, cho phụ nữ sau mãn kinh và nam giới từ 50 tuổi trở lên. Được công nhận bởi NICE, hướng dẫn này có liên quan tới tất cả các chuyên gia y tế tham gia quản lý loãng xương.

Giới thiệu

Nhóm Hướng dẫn Loãng xương Quốc gia Vương quốc Anh (NOGG) lần đầu tiên sản xuất một hướng dẫn về phòng ngừa và điều trị loãng xương vào năm 2008, với các cập nhật vào các năm 2013 và 2017. Bài báo này trình bày một bản cập nhật lớn của hướng dẫn, với phạm vi nhằm xem xét việc đánh giá và quản lý loãng xương cũng như phòng ngừa gãy xương ở phụ nữ sau mãn kinh và nam giới từ 50 tuổi trở lên.

Phương pháp

Nơi có sẵn, các đánh giá có hệ thống, phân tích tổng hợp và các thử nghiệm ngẫu nhiên có kiểm soát đã được sử dụng để cung cấp cơ sở chứng cứ. Kết luận và khuyến nghị đã được đánh giá một cách có hệ thống theo mức độ mạnh của chứng cứ hiện có.

Kết quả

Đánh giá bằng chứng và khuyến nghị được cung cấp cho việc chẩn đoán loãng xương, đánh giá rủi ro gãy xương và ngưỡng can thiệp, quản lý gãy xương đốt sống, các phương pháp điều trị không dược lý và dược lý, bao gồm thời gian và giám sát liệu pháp kháng tái hấp thu, loãng xương do glucocorticoid, và các mô hình chăm sóc nhằm phòng ngừa gãy xương. Khuyến nghị được đưa ra cho đào tạo; các lãnh đạo dịch vụ và nhà tài trợ dịch vụ y tế; và cho các tiêu chí xem xét nhằm đánh giá và cải thiện chất lượng.

Kết luận

Hướng dẫn, đã được công nhận bởi Viện Quốc gia về Sức khỏe và Chất lượng chăm sóc (NICE), cung cấp một cái nhìn tổng quan toàn diện về việc đánh giá và quản lý loãng xương cho tất cả các chuyên gia y tế tham gia quản lý bệnh này. Bài báo vị trí này đã được Tổ chức Loãng xương Quốc tế và Hội Châu Âu về các Khía cạnh Lâm sàng và Kinh tế của Loãng xương, Viêm khớp và các Bệnh về Cơ xương khớp tán thành.

Từ khóa


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