Tyr323-dependent p38 activation is associated with rheumatoid arthritis and correlates with disease activity
Tóm tắt
Từ khóa
Tài liệu tham khảo
Dong, 2002, MAP kinases in the immune response, Annu Rev Immunol, 20, 55, 10.1146/annurev.immunol.20.091301.131133
Kato, 1997, BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C, EMBO J, 16, 7054, 10.1093/emboj/16.23.7054
Davis, 2000, Signal transduction by the JNK group of MAP kinases, Cell, 103, 239, 10.1016/S0092-8674(00)00116-1
Ambrosino, 2001, Cell cycle regulation by p38 MAP kinases, Biol Cell, 93, 47, 10.1016/S0248-4900(01)01124-8
Crawley, 1997, T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation, J Biol Chem, 272, 15023, 10.1074/jbc.272.23.15023
Rincon, 1998, Interferon-γ expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway, EMBO J, 17, 2817, 10.1093/emboj/17.10.2817
Merritt, 2000, Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8+ but not CD4+ T cells, Mol Cell Biol, 20, 936, 10.1128/MCB.20.3.936-946.2000
Rincon, 2003, JNK and p38 MAP kinases in CD4+ and CD8+ T cells, Immunol Rev, 192, 131, 10.1034/j.1600-065X.2003.00019.x
Miossec, 1997, Th1/Th2 cytokine balance in arthritis, Arthritis Rheum, 40, 2105, 10.1002/art.1780401203
Miossec, 1997, The role of the Th1 and Th2 dichotomy in the pathogenesis of juvenile chronic arthritis, Rev Rhum Engl Ed, 64, 138
Han, 1994, A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells, Science, 265, 808, 10.1126/science.7914033
Rouse, 1994, A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins, Cell, 78, 1027, 10.1016/0092-8674(94)90277-1
Lee, 1994, A protein kinase involved in the regulation of inflammatory cytokine biosynthesis, Nature, 372, 739, 10.1038/372739a0
Freshney, 1994, Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27, Cell, 78, 1039, 10.1016/0092-8674(94)90278-X
Kumar, 2003, p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases, Nat Rev Drug Discov, 2, 717, 10.1038/nrd1177
Badger, 1996, Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function, J Pharmacol Exp Ther, 279, 1453
Badger, 2000, Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis, Arthritis Rheum, 43, 175, 10.1002/1529-0131(200001)43:1<175::AID-ANR22>3.0.CO;2-S
Pargellis, 2003, Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis, Curr Opin Investig Drugs, 4, 566
Wada, 2005, R-130823, a novel inhibitor of p38 MAPK, ameliorates hyperalgesia and swelling in arthritis models, Eur J Pharmacol, 506, 285, 10.1016/j.ejphar.2004.11.013
Thalhamer, 2008, MAPKs and their relevance to arthritis and inflammation, Rheumatology (Oxford), 47, 409, 10.1093/rheumatology/kem297
Derijard, 1995, Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms, Science, 267, 682, 10.1126/science.7839144
Raingeaud, 1996, MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway, Mol Cell Biol, 16, 1247, 10.1128/MCB.16.3.1247
Jiang, 1997, Structure-function studies of p38 mitogen-activated protein kinase: loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection, J Biol Chem, 272, 11096, 10.1074/jbc.272.17.11096
Bellon, 1999, The structure of phosphorylated p38γ is monomeric and reveals a conserved activation-loop conformation, Structure, 7, 1057, 10.1016/S0969-2126(99)80173-7
Salvador, 2005, Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases, Nat Immunol, 6, 390, 10.1038/ni1177
Mittelstadt, 2005, Activating p38 MAPK: new tricks for an old kinase, Cell Cycle, 4, 1189, 10.4161/cc.4.9.2043
Rudd, 2005, MAPK p38: alternative and nonstressful in T cells, Nat Immunol, 6, 368, 10.1038/ni0405-368
Ashwell, 2006, The many paths to p38 mitogen-activated protein kinase activation in the immune system, Nat Rev Immunol, 6, 532, 10.1038/nri1865
Salvador, 2005, The autoimmune suppressor Gadd45α inhibits the T cell alternative p38 activation pathway, Nat Immunol, 6, 396, 10.1038/ni1176
Jirmanova, 2009, Genetic disruption of p38α Tyr323 phosphorylation prevents T-cell receptor-mediated p38α activation and impairs interferon-γ production, Blood, 113, 2229, 10.1182/blood-2008-04-153304
Arnett, 1988, The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis, Arthritis Rheum, 31, 315, 10.1002/art.1780310302
Van der Linden, 1984, Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria, Arthritis Rheum, 27, 361, 10.1002/art.1780270401
Prevoo, 1995, Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis, Arthritis Rheum, 38, 44, 10.1002/art.1780380107
Salvador, 2002, Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome, Immunity, 16, 499, 10.1016/S1074-7613(02)00302-3
Hardin, 2007, Generalized linear models and extensions
Garfield, 2005, Regulation of p38 MAP kinase in CD4+ lymphocytes by infliximab therapy in patients with rheumatoid arthritis, Clin Immunol, 116, 101, 10.1016/j.clim.2005.04.010
Liu, 2007, T cell-directed therapies: lessons learned and future prospects, Nat Immunol, 8, 25, 10.1038/ni1429
Isaacs, 2008, Therapeutic T-cell manipulation in rheumatoid arthritis: past, present and future, Rheumatology (Oxford), 47, 1461, 10.1093/rheumatology/ken163
Ge, 2002, MAPKK-independent activation of p38α mediated by TAB1-dependent autophosphorylation of p38α, Science, 295, 1291, 10.1126/science.1067289
Ohkusu-Tsukada, 2004, Regulation of the maintenance of peripheral T-cell anergy by TAB1-mediated p38α activation, Mol Cell Biol, 24, 6957, 10.1128/MCB.24.16.6957-6966.2004
Kim, 2005, p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection, J Immunol, 174, 4178, 10.4049/jimmunol.174.7.4178
Zhou, 2006, Determinants that control the specific interactions between TAB1 and p38α, Mol Cell Biol, 26, 3824, 10.1128/MCB.26.10.3824-3834.2006
Diskin, 2007, Structures of p38α active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation, J Mol Biol, 365, 66, 10.1016/j.jmb.2006.08.043
Mittelstadt, 2009, T cell receptor-mediated activation of p38α by mono-phosphorylation of the activation loop results in altered substrate specificity, J Biol Chem, 284, 15469, 10.1074/jbc.M901004200