Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model
Sanne D'hondt1, Brecht Guillemyn1, Delfien Syx1, Sofie Symoens1, Riet De Rycke2,3,4,5, Leen Vanhoutte2,6, Wendy Toussaint2,6, Bart N. Lambrecht2,6,7,8, Anne De Paepe1, Douglas R. Keene9, Yoshihiro Ishikawa10, Hans Peter Bächinger10, Sophie Janssens2,6,7,8, Mathieu J.M. Bertrand2,3,7, Fransiska Malfait1
1Center for Medical Genetics, Ghent University and University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
2VIB Center for Inflammation Research, Technologiepark 927, 9052 Ghent, Belgium
3Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, 9052 Ghent, Belgium
4VIB Center for Plant Systems Biology, Technologiepark 927, 9052 Ghent, Belgium
5Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, 9052, Ghent, Belgium
6Laboratory of Immunoregulation and Mucosal Immunology, VIB Center for Inflammation Research, Technologiepark 927, 9052 Ghent, Belgium
7GROUP-ID Consortium, Ghent University and University Hospital, De Pindelaan 185, 9000 Ghent, Belgium
8Department of Internal Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
9Micro-imaging Center, Shriners Hospitals for Children Portland, 3101 SW Sam Jackson Park Rd, Portland, OR 97239, United States
10Department of Biochemistry and Molecular Biology, Oregon Health & Science University Portland and Shriners Hospitals for Children Portland, 3101 SW Sam Jackson Park Rd, Portland, OR 97239, United States