Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Nature - Tập 401 Số 6754 - Trang 708-712 - 1999
Federica Sallusto1, Danielle Lenig2, Reinhold Förster3, Martin Lipp3, Antonio Lanzavecchia2
1Basel Institute for Immunology, Switzerland
2Basel Institute for Immunology, Basel, Switzerland
3Max Delbrueck Center for Molecular Medicine Berlin‐Buch Germany

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Butcher,E. C. & Picker,L. J. Lymphocyte homing and homeostasis. Science 272, 60–66 (1996).

Banchereau,J. & Steinman,R. M. Dendritic cells and the control of immunity. Nature 392, 245–252 (1998).

MacLennan,I. C. et al. The changing preference of T and B cells for partners as T-dependent antibody responses develop. Immunol. Rev. 156, 53–66 (1997).

Garside,P. et al. Visualization of specific B and T lymphocyte interactions in the lymph node. Science 281, 96–99 (1998).

Mackay,C. R. Homing of naive, memory and effector lymphocytes. Curr. Opin. Immunol. 5, 423–427 (1993).

Austrup,F. et al. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385, 81–83 (1997).

Ahmed,R. & Gray,D. Immunological memory and protective immunity: understanding their relation. Science 272, 54–60 (1996).

Zinkernagel,R. M. et al. On immunological memory. Annu. Rev. Immunol. 14, 333–367 (1996).

Dutton,R. W., Bradley,L. M. & Swain,S. L. T cell memory. Annu. Rev. Immunol. 16, 201–223 (1998).

Gunn,M. D. et al. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl Acad. Sci USA 95, 258–263 (1998).

Campbell,J. J. et al. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279, 381–384 (1998).

Campbell,J. J. et al. 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3β receptor CCR7. J. Cell Biol. 141, 1053–1059 (1998).

Mackay,C. R., Marston,W. L. & Dudler,L. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J. Exp. Med. 171, 801–817 (1990).

Baggiolini,M. Chemokines and leukocyte traffic. Nature 392, 565–568 (1998).

Gunn,M. D. et al. Mice lacing expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 189, 451–460 (1999).

Michie,C. A., McLean,A., Alcock,C. & Beverley,P. C. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature 360, 264–265 (1992).

Baron,J. L., Madri,J. A., Ruddle,N. H., Hashim,G. & Janeway, C. A. Jr Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 177, 57–68 (1993).

Wu,L. et al. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185, 1681–1691 (1997).

Sallusto,F., Mackay,C. R. & Lanzavecchia,A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277, 2005–2007 (1997).

Tang,H. L. & Cyster,J. G. Chemokine up-regulation and activated T cell attraction by maturing dendritic cells. Science 284, 819–822 (1999).

Sallusto,F., Lenig,D., Mackay,C. R. & Lanzavecchia,A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187, 875–883 (1998).

Grewal,I. S. & Flavell,R. A. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16, 111–135 (1998).

Abbas,A. K., Murphy,K. M. & Sher,A. Functional diversity of helper T lymphocytes. Nature 383, 787–793 (1996).

Kagi,D., Ledermann,B., Burki,K., Zinkernagel,R. M. & Hengartner,H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 14, 207–232 (1996).

Casamayor-Palleja,M., Khan,M. & MacLennan,I. C. A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex. J. Exp. Med. 181, 1293–1301 (1995).

Hamann,D. et al. Phenotypic and functional separation of memory and effector human CD8+ T cells. J. Exp. Med. 186, 1407–1418 (1997).

Sprent,J., Tough,D. F. & Sun,S. Factors controlling the turnover of T memory cells. Immunol. Rev. 156, 79–85 (1997).

Tanchot,C. & Rocha,B. The organization of mature T-cell pools. Immunol. Today 19, 575–579 (1998).

Weng,N. P., Hathcock,K. S. & Hodes,R. J. Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential. Immunity 9, 151–157 (1998).