Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene

Aprison, 1990, The discovery of the neurotransmitter role of glycine, 1 Axelrod, 1971, Noradrenaline: fate and control of its biosynthesis, Science, 173, 598, 10.1126/science.173.3997.598 Black, 1992, Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro, Cell, 69, 795, 10.1016/0092-8674(92)90291-J Blakely, 1991, Cloning and expression of a functional serotonin transporter from rat brain, Nature, 354, 66, 10.1038/354066a0 Borden, 1992, Molecular heterogeneity of the gamma-aminobutyric acid (GABA) transport system, J. Biol. Chem., 267, 21098, 10.1016/S0021-9258(19)36802-4 Christensen, 1984, Organic ion transport during seven decades. The amino acids, Biochim. Biophys. Acta, 779, 255, 10.1016/0304-4157(84)90012-1 Christensen, 1981, Role of system GLY in glycine transport in monolayer cultures of liver cells, Biochem. Biophys. Res. Commun., 98, 102, 10.1016/0006-291X(81)91875-1 Clark, 1992, Functional expression and CNS distribution of a β-alanine-sensitive neuronal GABA transporter, Neuron, 9, 337, 10.1016/0896-6273(92)90172-A Currie, 1981, Glial versus neuronal uptake of glutamate, J. Exp. Biol., 95, 181, 10.1242/jeb.95.1.181 Devereux, 1984, A comprehensive set of sequence analysis programs for the VAX, Nucl. Acids Res., 12, 387, 10.1093/nar/12.1Part1.387 Fagg, 1983, Amino acid neurotransmitters and their pathways in the mammalian central nervous system, J. Neurosci., 9, 701, 10.1016/0306-4522(83)90263-4 Fremeau, 1992, Molecular cloning and expression Of a high affinity l-proline transporter expressed in putative glutamatergic pathways of rat brain, Neuron, 8, 915, 10.1016/0896-6273(92)90206-S Giros, 1991, Cloning and functional characterizaton of a cocaine-sensitive dopamine transporter, FEBS Lett., 295, 149, 10.1016/0014-5793(91)81406-X Guastella, 1990, Cloning and expression of a rat brain GABA transporter, Science, 249, 1303, 10.1126/science.1975955 Guastella, 1992, Cloning, expression, and localization of a rat brain high-affinity glycine transporter, 89, 7189 Gubler, 1983, A simple and very efficient method for generating cDNA libraries, Gene, 25, 263, 10.1016/0378-1119(83)90230-5 Hedgvist, 1969, The relative role of recapture and of de novo synthesis for the maintenance of neurotransmitter homeostasis in noradrenergic nerves, Acta Physiol. Scand., 76, 270, 10.1111/j.1748-1716.1969.tb04470.x Henn, 1976, Neurotransmission and glial cells: a functional relationship?, J. Neurosci. Res., 2, 271, 10.1002/jnr.490020404 Hoffman, 1991, Cloning of a serotonin trasporter affected by antidepressants, Science, 254, 579, 10.1126/science.1948036 Holopainen, 1989, Uptake and release of glycine in cerebellar granule cells and astrocytes in primary culture: potassium-stimulated release from granule cells is calcium-depend, J. Neurosci. Res., 24, 374, 10.1002/jnr.490240306 Iversen, 1971, Role of transmitter uptake mechanisms in synaptic neurotransmission, Br. J. Pharmacol., 41, 571, 10.1111/j.1476-5381.1971.tb07066.x Johnson, 1987, Glycine potentiates the NMDA response in cultured mouse brain neurons, Nature, 325, 529, 10.1038/325529a0 Kanai, 1992, Primary structure and functional characterization of a high-affinity glutamate transporter, Nature, 360, 467, 10.1038/360467a0 Kanner, 1987, Mechanism of transport and storage of neurotransmitters, CRC Crit. Rev. Biochem., 22, 1, 10.3109/10409238709082546 Kilpatrick, 1990, Transcription of the rat and mouse proenkephalin genes is initiated at distinct sites in spermatogenic and somatic cells, Mol. Cell. Biol., 10, 3717, 10.1128/MCB.10.7.3717 Kilty, 1991, Cloning and expression of a cocaine-sensitive rat dopamine transporter, Science, 254, 578, 10.1126/science.1948035 Kita, 1982, Evidence for a glycinergic cortico-lateral hypothalamic inhibitory pathway in the rat, Brain Res., 235, 131, 10.1016/0006-8993(82)90202-5 Kozak, 1987, An analysis of 5′-noncoding sequences from 699 vertebrate mRNA's, Nucl. Acids Res., 15, 8125, 10.1093/nar/15.20.8125 Kyte, 1982, A simple method for displaying the hydrophatic character of a protein, J. Mol. Biol., 157, 105, 10.1016/0022-2836(82)90515-0 Liu, 1992, Cloning and expression of a glycine transporter from mouse brain, FEBS Lett., 305, 110, 10.1016/0014-5793(92)80875-H Malosio, 1991, Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain, EMBO J., 70, 2401, 10.1002/j.1460-2075.1991.tb07779.x McGreer, 1980, Possible corticohypothalamic glycinergic tract, Neurosci. Lett., 17, 85, 10.1016/0304-3940(80)90066-X Mezey, 1991, Coexpression of vasopressin and oxytocin in hypothalamic supraoptic neurons of lactating rats, Endocrinology, 129, 1814, 10.1210/endo-129-4-1814 Ohta, 1979, Inhibitory pathway from the frontal cortex to the hypothalamic ventromedial nucleus in the rat, Brain Res. Bull., 4, 231, 10.1016/0361-9230(79)90287-9 Pacholczyk, 1991, Expression cloning of a cocaine- and antidepressant-sensitive human nor-adrenaline transporter, Nature, 350, 350, 10.1038/350350a0 Pines, 1992, Cloning and expression of a rat brain L-glutamate transporter, Nature, 360, 464, 10.1038/360464a0 Purcell, 1990, Differential release of histamine and 5-hydroxytryptamine from rat mast cells: the contribution of amine uptake to the apparent pattern of secretion, Agents Actions, 30, 38, 10.1007/BF01968992 Pycock, 1981, The status of glycine as a supraspinal neurotransmitter, Life Sci., 28, 2679, 10.1016/0024-3205(81)90168-5 Sato, 1992, Regional distribution of cells expressing glycine receptor α2 subunit mRNA in the rat brain, Brain Res., 590, 95, 10.1016/0006-8993(92)91085-S Seed, 1987, An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2, Nature, 329, 840, 10.1038/329840a0 Shimada, 1991, Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA, Science, 254, 567, 10.1126/science.1948034 Smith, 1989, Alternative splicing in the control of gene expression, Annu. Rev. Genet., 23, 527, 10.1146/annurev.ge.23.120189.002523 Smith, 1992, Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors, Neuron, 8, 927, 10.1016/0896-6273(92)90207-T Snyder, 1970, Putative neurotransmitters in the brain: selective neuronal uptake, subcellular localization, and interaction with centrally acting drugs, Biol. Psychiatry, 2, 367 Storck, 1992, Structure, expression, and functional analysis of a Na+-dependent glutamate/aspartate transporter from rat brain, 89, 10955 Takada, 1987, Glycine: an alternative transmitter candidate of the pallidosubthalamic projection neurons in the rat, J. Comp. Neurol., 262, 465, 10.1002/cne.902620402 Usdin, 1991, Cloning of the cocaine-sensitive bovine dopamine transporter, 88, 11168 Yamauchi, 1992, Cloning of a Na+- and Cl−-dependent betaine transporter that is regulated by hypertonicity, J. Biol. Chem., 267, 649, 10.1016/S0021-9258(18)48543-2 Young, 1986, Vasopressin and oxytocin mRNAs in adrenalectomized and Brattleboro rats: analysis by quantitative in situ hybridization histochemistry, Mol. Brain Res., 1, 231, 10.1016/0169-328X(86)90029-X Zafra, 1989, Characteristics and adaptive regulation of glycine transport in cultured glial cells, Biochem. J., 258, 403, 10.1042/bj2580403