Two Antinematodal Phenolics from Knema hookeriana, a Sumatran Rainforest Plant

Zeitschrift fur Naturforschung - Section C Journal of Biosciences - Tập 55 Số 3-4 - Trang 300-304 - 2000
Yohannes Alen1, Shûhei Nakajima2, Teruhiko Nitoda3,4, Naomichi Baba2, Hiroshi Kanzaki2, Kazuyoshi Kawazu3
1The Graduate School of Natural Science and Technology, Department of Applied Bioscience and Biotechnology, Laboratory of Natural Products Chemistry, Okayama University, Tsushima naka 3-1-1, Okayama 700-8530, Japan. / Faculty of Agriculture, Okayama University, Tsushima naka 1-1-1, Okayama 700-8530, Japan / On Leave from Laboratory of Natural Products Chemistry Department of Pharmacy, Faculty of Mathematic and Natural Sciences, Andalas University, Padang, Indonesia
2The Graduate School of Natural Science and Technology, Department of Applied Bioscience and Biotechnology, Laboratory of Natural Products Chemistry, Okayama University, Tsushima naka 3-1-1, Okayama 700-8530, Japan. / Faculty of Agriculture, Okayama University, Tsushima naka 1-1-1, Okayama 700-8530, Japan
3Faculty of Agriculture, Okayama University, Tsushima naka 1-1-1, Okayama 700-8530, Japan
4Graduate School of Environmental and Life Science

Tóm tắt

Abstract The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimun effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/ bl.) or 0.018 and 0.073 μᴍ/cotton ball (μᴍ/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.

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Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Tập 55 Số 3-4

300-304

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