Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bigner, 1990, Cytogenetics and molecular genetics of malignant gliomas and medulloblastoma, Brain Pathol., 1, 12, 10.1111/j.1750-3639.1990.tb00633.x
Brazel, 2005, Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain, Aging Cell, 4, 197, 10.1111/j.1474-9726.2005.00158.x
Capela, 2002, LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal, Neuron, 35, 865, 10.1016/S0896-6273(02)00835-8
Deschavanne, 1996, A review of human cell radiosensitivity in vitro, Int. J. Radiat. Oncol. Biol. Phys., 34, 251, 10.1016/0360-3016(95)02029-2
Dontu, 2003, In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells, Genes Dev., 17, 1253, 10.1101/gad.1061803
Duensing, 2005, Guilt by association? p53 and the development of aneuploidy in cancer, Biochem. Biophys. Res. Commun., 331, 694, 10.1016/j.bbrc.2005.03.157
Fortunel, 2003, Comment on “‘Stemness’: Transcriptional profiling of embryonic and adult stem cells” and “A stem cell molecular signature.”, Science, 302, 393, 10.1126/science.1086384
Fujiwara, 2005, Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells, Nature, 437, 1043, 10.1038/nature04217
Gage, 1995, Isolation, characterization, and use of stem cells from the CNS, Annu. Rev. Neurosci., 18, 159, 10.1146/annurev.ne.18.030195.001111
Galli, 2004, Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma, Cancer Res., 64, 7011, 10.1158/0008-5472.CAN-04-1364
Giannini, 2005, Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme, Neuro-oncol., 7, 164, 10.1215/S1152851704000821
Haik, 2000, Fibroblast growth factor 2 up regulates telomerase activity in neural precursor cells, Oncogene, 19, 2957, 10.1038/sj.onc.1203596
Hecht, 1995, Cytogenetics of malignant gliomas: I. The autosomes with reference to rearrangements, Cancer Genet. Cytogenet., 84, 1, 10.1016/0165-4608(95)00091-7
Hemmati, 2003, Cancerous stem cells can arise from pediatric brain tumors, Proc. Natl. Acad. Sci. USA, 100, 15178, 10.1073/pnas.2036535100
Huang, 2004, Whole genome DNA copy number changes identified by high density oligonucleotide arrays, Hum. Genomics, 1, 287, 10.1186/1479-7364-1-4-287
Huntly, 2005, Leukaemia stem cells and the evolution of cancer-stem-cell research, Nat. Rev. Cancer, 5, 311, 10.1038/nrc1592
Kim, 2005, Identification of bronchioalveolar stem cells in normal lung and lung cancer, Cell, 121, 823, 10.1016/j.cell.2005.03.032
Kleihues, 2002, The WHO classification of tumors of the nervous system, J. Neuropathol. Exp. Neurol., 61, 215, 10.1093/jnen/61.3.215
Kondo, 2004, Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells, Genes Dev., 18, 2963, 10.1101/gad.309404
Kondo, 2004, Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line, Proc. Natl. Acad. Sci. USA, 101, 781, 10.1073/pnas.0307618100
Kubota, 2001, Identification of recurrent chromosomal rearrangements and the unique relationship between low-level amplification and translocation in glioblastoma, Genes Chromosomes Cancer, 31, 125, 10.1002/gcc.1126
Lendahl, 1990, CNS stem cells express a new class of intermediate filament protein, Cell, 60, 585, 10.1016/0092-8674(90)90662-X
Li, 2001, Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection, Proc. Natl. Acad. Sci. USA, 98, 31, 10.1073/pnas.98.1.31
Maher, 2001, Malignant glioma: genetics and biology of a grave matter, Genes Dev., 15, 1311, 10.1101/gad.891601
Mao, 2004, Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene, Nature, 432, 775, 10.1038/nature03155
McKay, 1997, Stem cells in the central nervous system, Science, 276, 66, 10.1126/science.276.5309.66
Mehrian Shai, 2005, Robustness of gene expression profiling in glioma specimen samplings and derived cell lines, Brain Res. Mol. Brain Res., 136, 99, 10.1016/j.molbrainres.2005.01.017
Morshead, 2004, Disguising adult neural stem cells, Curr. Opin. Neurobiol., 14, 125, 10.1016/j.conb.2004.01.008
Ostenfeld, 2000, Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation, Exp. Neurol., 164, 215, 10.1006/exnr.2000.7427
Pardal, 2003, Applying the principles of stem-cell biology to cancer, Nat. Rev. Cancer, 3, 895, 10.1038/nrc1232
Park, 2003, Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells, Nature, 423, 302, 10.1038/nature01587
Patrawala, 2005, Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2− cancer cells are similarly tumorigenic, Cancer Res., 65, 6207, 10.1158/0008-5472.CAN-05-0592
Phillips, 2006, Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis, Cancer Cell, 9, 157, 10.1016/j.ccr.2006.02.019
Rajagopalan, 2004, Inactivation of hCDC4 can cause chromosomal instability, Nature, 428, 77, 10.1038/nature02313
Ramalho-Santos, 2002, “Stemness”: transcriptional profiling of embryonic and adult stem cells, Science, 298, 597, 10.1126/science.1072530
Reynolds, 1992, A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes, J. Neurosci., 12, 4565, 10.1523/JNEUROSCI.12-11-04565.1992
Romer, 2005, Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics, Cancer Res., 65, 4975, 10.1158/0008-5472.CAN-05-0481
Sakakibara, 1996, Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell, Dev. Biol., 176, 230, 10.1006/dbio.1996.0130
Sanai, 2005, Neural stem cells and the origin of gliomas, N. Engl. J. Med., 353, 811, 10.1056/NEJMra043666
Shin, 2003, Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability, Cancer Cell, 4, 483, 10.1016/S1535-6108(03)00302-7
Singh, 2003, Identification of a cancer stem cell in human brain tumors, Cancer Res., 63, 5821
Singh, 2004, Identification of human brain tumour initiating cells, Nature, 432, 396, 10.1038/nature03128
Taylor, 2005, Radial glia cells are candidate stem cells of ependymoma, Cancer Cell, 8, 323, 10.1016/j.ccr.2005.09.001
Wiltshire, 2000, Comparative genetic patterns of glioblastoma multiforme: potential diagnostic tool for tumor classification, Neuro-oncol., 2, 164, 10.1093/neuonc/2.3.164
Yang, 2004, Aurora-A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells, Cancer Res., 64, 463, 10.1158/0008-5472.CAN-03-2907
Yuan, 2004, Isolation of cancer stem cells from adult glioblastoma multiforme, Oncogene, 23, 9392, 10.1038/sj.onc.1208311