Trophic effects of purines in neurons and glial cells
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Abbracchio, 1994, Purinoceptors: are there families of P2X and P2Y purinoceptors?, Pharmac. Ther., 64, 445, 10.1016/0163-7258(94)00048-4
Abbracchio, 1989, Adenosine receptors linked to adenylate cyclase activity in human neuroblastoma cells: modulation during cell differentiation, Neuroscience, 30, 819, 10.1016/0306-4522(89)90173-5
Abbracchio, 1993, Effect of purine analogs on astroglial cells in rat CNS primary cultures, Soc. Neurosci., 19, 88
Abbracchio, 1994, Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum, Neuroscience, 59, 67, 10.1016/0306-4522(94)90099-X
Abbracchio, 1995, A novel action for adenosine: apoptosis of astroglial cells in rat brain primary cultures, Biochem. biophys. Res. Commun., 213, 908, 10.1006/bbrc.1995.2215
Abbracchio, 1997, Modulation of apoptosis by adenosine in the central nervous system: a possible role for the A3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders, Ann. N.Y. Acad. Sci., 825, 11, 10.1111/j.1749-6632.1997.tb48410.x
Abbracchio, 1997, The A3 adenosine receptor mediates cell spreading reorganization of actin cytoskeleton, and distribution of Bcl-xL. Studies in human astroglioma cells, Biochem. biophys. Res. Commun., 241, 297, 10.1006/bbrc.1997.7705
Abraham, 1993, The multidrug resistance (mdr1) gene product functions as an ATP channel, Proc. natl Acad. Sci. USA, 90, 312, 10.1073/pnas.90.1.312
Al-Awqati, 1995, Regulation of ion channels by ABC transporters that secrete ATP, Science, 269, 805, 10.1126/science.7543697
Ando, 1990, Distribution of guanine and hypoxanthine in the integument of spawning-migrating Chum. salmon, Nippon Suisan Gakkaishi, 56, 551, 10.2331/suisan.56.551
Angielski, 1983, Transport of adenosine by renal brush border membranes, Pflügers Arch., 397, 75, 10.1007/BF00585174
Aruffo, 1987, Low doses of l-monosodium glutamate promote neuronal growth and differentiation in vitro, Dev. Neurosci., 9, 228, 10.1159/000111625
Balazas, 1988, Stimulation of the N-methyl-d-aspartate receptor has a trophic effect on differentiating cerebellar granule cells, Neurosci. Lett., 87, 80, 10.1016/0304-3940(88)90149-8
Balazas, 1988, N-methyl-d-aspartate promotes the survival of cerebellar granule cells in culture, Neuroscience, 27, 437, 10.1016/0306-4522(88)90279-5
Ballerini, 1993, TMB-8 and thapsigargin modulate purine release from dissociated primary cultures of rat brain astrocytes, Res. Commun. Chem. Path., 82, 167
Ballerini, 1995, P2-induced [Ca2+]i modification in rat cultured glial cells, Res. Commun. Mol Pathol. Pharmac., 87, 40
Ballerini, 1995, Influence of Ca2+ channel modulators on [3H]purine release from rat cultured glial cells, Neurochem. Res., 20, 627, 10.1007/BF01705538
Ballerini, 1996, Rat astroglial P2Z receptors regulate intracellular calcium and purine release, Neuroreport, 7, 2533, 10.1097/00001756-199611040-00026
Barbieri, 1998, Apoptosis by 2-chloro-2′-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells, Neurochem. Int., 32, 493, 10.1016/S0197-0186(97)00129-0
Beal, 1992, Mechanisms of excitotoxicity in neurologic diseases, FASEB J., 6, 3338, 10.1096/fasebj.6.15.1464368
Bean, 1990, ATP-activated channels in excitable cells, 196
Belhage, 1993, Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA, Neuroscience, 54, 1019, 10.1016/0306-4522(93)90592-4
Bender, 1990, The role of phosphoinositide hydrolysis in volume regulation in astrocytes, Abstr. Soc. Neurosci., 16, 667
BenEzra, 1978, Neovasculogenic ability of prostaglandins, growth factors and synthetic chemoattractants, Am. J. Ophthamol., 86, 455, 10.1016/0002-9394(78)90289-1
Berger, 1985, Distribution of guanine deaminase in mouse brain, J. Neurochem., 44, 1736, 10.1111/j.1471-4159.1985.tb07162.x
Biber, 1997, Adenosine Al receptor-mediated activation of phospholipase C in cultured astrocytes depends on the level of receptor expression, J. Neurosci., 17, 4956, 10.1523/JNEUROSCI.17-13-04956.1997
Bignami, 1991, Glial cells in the central nervous system, Disc. Neurosci., 8, 11
Blazynski, 1989, Displaced cholinergic, GABAergic amacrine cells in the rabbit retina also contain adenosine, Visual Neurosci., 3, 425, 10.1017/S0952523800005927
Boarder, 1995, G protein-coupled P2 purinoceptors: from molecular biology to functional responses, Trends Pharmac. Sci., 16, 133, 10.1016/S0165-6147(00)89001-X
Bolego, 1997, Characterization of the signaling pathways involved in ATP and basic fibroblast growth factor-induced astrogliosis, Br. J. Pharmac., 121, 1692, 10.1038/sj.bjp.0701294
Borgland, 1997, Uptake and release of [3H]formycin B via sodium dependent nucleoside transporters of mouse leukemic L1210/M.A27.1 cells, J. Pharmac. exp. Ther., 281, 347
Braas, 1986, Adenosine-containing neurons in the brain localized by immunocytochemistry, J. Neurosci., 6, 1952, 10.1523/JNEUROSCI.06-07-01952.1986
Braumann, 1986, Fate of cyclic nucleotides in PC12 cell cultures: uptake, metabolism and effects of metabolites on nerve growth factor-induced neurite outgrowth, J. Neurochem., 47, 912, 10.1111/j.1471-4159.1986.tb00697.x
Brewer, 1989, NMDA receptor regulation of neuronal morphology in cultured hippocampal neurons, Neurosci. Lett., 99, 268, 10.1016/0304-3940(89)90458-8
Brosh, 1990, Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain, J. Neurochem., 54, 1776, 10.1111/j.1471-4159.1990.tb01233.x
Brundege, 1997, Role of adenosine as a modulator of synaptic activity in the central. nervous system, Adv. Pharmac., 39, 353, 10.1016/S1054-3589(08)60076-9
Bruner, 1990, ATP-evoked arachidonic acid mobilization in astrocytes is via P2Y-purinergic receptor, J. Neurochem., 55, 1569, 10.1111/j.1471-4159.1990.tb04940.x
Bruno, 1994, Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death, Eur. J. Pharmac., 245, 109, 10.1016/0014-2999(94)90624-6
Bruno, 1997, The neuroprotective activity of group-II metabotropic glutamate receptors require new protein synthesis and involves a glial-neuronal interaction, J. Neurosci., 17, 1891, 10.1523/JNEUROSCI.17-06-01891.1997
Bruno, V., Battaglia, G., Ngomba, R. and Nicoletti, F. 1998. A role for TGF8 in in vitro and in vivo neuroprotection mediated by glial metabotropic glutamate receptors. In: Abstracts of the 6th Joint Meeting of Italian, Hungarian and Polish Pharmacological Societies, No. 5.
Bulloch, 1989, Sprouting by intact helisoma neurons: role for glutamate, J. Neurosci. Res., 23, 384, 10.1002/jnr.490230404
Bulloch, 1990, Sprouting by isolated helisoma neurons: enhancement by glutamate, Int. J. Dev. Neurosci., 8, 391, 10.1016/0736-5748(90)90072-A
Burnstock, 1972, Purinergic nerves, Pharmac. Rev., 24, 509
Burnstock, 1978, A basis for distinguishing two types of purinergic receptor, 107
Burnstock, 1991, Distribution and roles of purinoceptor subtypes, Nucleos. Nucleotid., 10, 917, 10.1080/07328319108047230
Burnstock, 1993, Physiological and pathological roles of purines: an update, Drug Dev. Res., 28, 195, 10.1002/ddr.430280303
Caciagli, 1996, mGluRs and purinoceptors cooperate in regulating excitatory amino acid and purine release, Neuropsychopharmacology, 35, 24
Caciagli, 1988, Cultures of glial cells release purines under field electrical stimulation: the possible ionic mechanism, Pharmac. Res. Commun., 20, 935, 10.1016/S0031-6989(88)80122-X
Caciagli, 1989, Influence of PLA-PG system on purine release and cAMP content in dissociated primary glial cultures from rat striatum, Pharmac. Res., 21, 271, 10.1016/S1043-6618(89)80005-2
van Calker, 1979, Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells, J. Neurochem., 33, 999, 10.1111/j.1471-4159.1979.tb05236.x
Cantiello, 1994, External ATP and its analogs activate the cystic fibrosis transmembrane conductance regulator by a cyclic AMP-independent mechanism, J. Biol. Chem., 269, 11224, 10.1016/S0021-9258(19)78114-9
Cartmell, 1994, Modulation of cyclic AMP formation by putative metabotropic receptor agonists, Br. J. Pharmac., 111, 364, 10.1111/j.1476-5381.1994.tb14069.x
Casabona, 1994, Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices, Brain Res., 645, 13, 10.1016/0006-8993(94)91632-2
Ceballos, 1994, Differential. distribution of purine metabolizing enzymes between glia and neurons, J. Neurochem., 62, 1144, 10.1046/j.1471-4159.1994.62031144.x
Ceruti, 1977, Different pathways of apoptosis revealed by 2-chloro-adenosine and deoxy-d-ribose in mammalian astroglial cells, J. Neurosci. Res., 47, 372, 10.1002/(SICI)1097-4547(19970215)47:4<372::AID-JNR2>3.0.CO;2-B
Ceruti, 1997, 2-Chloro-adenosine-induced apoptosis of human ADF astroglioma cells, Abstracts of the Soc. Neurosci., 23, 71
Charriaut-Marlangue, 1996, Apoptotic feature of selective neuronal. death in ischemia, epilepsy and gp 120 toxicity, Trends Neurosci., 19, 109, 10.1016/S0166-2236(96)80039-7
Chen, 1996, ATP-evoked inositol phosphates formation through activation of P2U purinergic receptors in cultured astrocytes: Regulation by PKC subtypes a, d and q, GLIA, 17, 63, 10.1002/(SICI)1098-1136(199605)17:1<63::AID-GLIA6>3.0.CO;2-8
Chen, 1996, Effects of dietary nucleoside-nucleotide mixture on memory in aged and young memory deficient mice, Life Sci., 59, 325, 10.1016/0024-3205(96)00526-7
Chen, 1992, Release of endogenous adenosine and its metabolites by the activation of NMDA receptors in the rat hippocampus in vivo, Br. Pharmac., 106, 632, 10.1111/j.1476-5381.1992.tb14387.x
Chiu, 1994, Neurotransmitter-mediated signaling between axons and glial cells, GLIA, 11, 191, 10.1002/glia.440110213
Christjanson, 1993, Stimulation of astrocyte proliferation by purine and pyrimidine nucleotides and nucleosides, GLIA, 7, 176, 10.1002/glia.440070207
Churchill, 1990, Adenosine and renal function, 335
Ciccarelli, 1994, Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes, J. Neurosci. Res., 39, 556, 10.1002/jnr.490390507
Ciccarelli, 1996, Modulation by metabotropic glutamate receptors of GTP effect on rat astrocyte proliferation, Drug Dev. Res., 37, 168
Ciccarelli, R., Di Iorio, P., Middlemiss, P. J., Ballerini, P., D'Alimonte, J., Rathbone, M. P. and Caciagli, F. 1997. Potential neuroprotective effects of guanine-based purines released from rat cultured astrocytes. In: Proceedings of the 11 International EPHAR Meeting, Drug Targets in Heart and Brain Ischemia, p. 39.
Ciccarelli, A., Casabona, G., Di Iorio, P., Ballerini, P., D'Alimonte, I., Nicoletti, F. and Caciagli, F. 1998a. Adenosine Al and group 11 metabotropic glutamate receptors increase nerve growth factor and S100 protein production from rat cultured astrocytes. In: Abstracts of the 6th meeting of the Italian and Hungarian and Polish Pharmalogical Societies, No. 6.
Ciccarelli, 1998, Stimulation of nerve growth factor and S100 protein production from rat cultured astrocytes by adenosine Al and group 1.1 metabotropic glutamate receptors, Drug Dev. Res., 43, 51
Ciccarelli, 1999, Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia, GLIA, 25, 93, 10.1002/(SICI)1098-1136(19990101)25:1<93::AID-GLIA9>3.0.CO;2-N
Ciruela, 1996, Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors, FEBS Lett., 380, 219, 10.1016/0014-5793(96)00023-3
Clark, 1993, External GTP alters the motility and elicits an oscillating membrane depolarization in Paramecium tetraurelia, Proc. natl Acad. Sci. USA, 90, 3782, 10.1073/pnas.90.9.3782
Claude, 1988, Acidic fibroblast growth factor stimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long-term survival factor, Neuron, 1, 783, 10.1016/0896-6273(88)90126-2
Cloues, 1995, Properties of ATP-gated channels recorded from rat sympathetic neurons: voltage dependence and regulation by Zn ions, J. Neurochem., 73, 312
Collis, 1993, Adenosine receptor subtypes, Trends Pharmac. Sci., 14, 360, 10.1016/0165-6147(93)90094-Z
Craig, 1993, N-Methyl-d-aspartate and non-N-methyl-d-aspartate evoked adenosine release from rat cortical slices: distinct purinergic sources and mechanisms of release, J. Neurochem., 60, 1073, 10.1111/j.1471-4159.1993.tb03256.x
Crocker, 1997, Effect of AIT-082 on neurotrophin levels following spinal cord hemisection, Abstr. Soc. Neurosci., 23, 1149
Cunha, 1991, Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog, Eur. J. Pharmac., 197, 83, 10.1016/0014-2999(91)90368-Z
Cunha, 1993, Adenosine and adenine nucleotides are independently released from both the nerve terminals and the muscle fibres upon electrical stimulation of the innervated skeletal muscle of the frog, Pflügers Arch., 424, 503, 10.1007/BF00374914
Cunha, 1992, Adenosine A2a receptors stimulate acetylcholine release from nerve terminals of the rat hippocampus, Neurosci. Lett., 196, 41, 10.1016/0304-3940(95)11833-I
DaPrada, 1981, Vol. 2, 107
Daval, 1981, Release of radiolabelled adenosine derivatives from superfused synaptosome beds. Evidence for the output of adenosine, Biochem. Pharmac., 30, 2559, 10.1016/0006-2952(81)90583-9
Dawson, 1993, Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures, J. Neurosci., 13, 2651, 10.1523/JNEUROSCI.13-06-02651.1993
Di Iorio, 1988, Sodium and calcium-dependence of purine release from rat cerebral cortical slices, Pharmac. Res. Commun., 20, 51, 10.1016/S0031-6989(88)80078-X
Di Iorio, 1991, Al and A2 adenosine receptor involvement in controlling purine and acetylcholine release from rat hippocampal slices, Nucleos. Nucleoti., 10, 1237, 10.1080/07328319108047290
Di Iorio, 1995, Effect of DCG-IV-sensitive metabotropic glutamate receptors on purine and glutamate release from rat hippocampus slices and cultured astrocytes, Res. Commun. Mol. Pathol. Pharmac., 87, 57
Di Iorio, 1996, Interaction between Al adenosine and class 11 metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices, J. Neurochem., 67, 302, 10.1046/j.1471-4159.1996.67010302.x
Di Iorio, 1996, Al, mGluR2, GABAB receptors co-modulate purine and EAAs release from rat hippocampal synaptosomes, Drug Dev. Res., 37, 153
Di Iorio, 1998, Purinoceptor-mediated modulation of purine and neurotransmitter release from hippocampus, Pharmac. Res., 37, 169, 10.1006/phrs.1998.0286
Di Virgilio, 1990, Extracellular ATP as a possible mediator of cell-mediated cytotoxicity, Immun. Today, 11, 274, 10.1016/0167-5699(90)90111-L
Diamond, 1987, Evidence that endogenous β nerve growth factor is responsible for the collateral sprouting, but not the regeneration, of nociceptive axons in adult rats, Proc. natl Acad. Sci. USA, 84, 6596, 10.1073/pnas.84.18.6596
Diamond, 1992, Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF, J. Neurosci., 12, 1467, 10.1523/JNEUROSCI.12-04-01467.1992
Diamond, 1992, Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat, J. Neurosci., 12, 1454, 10.1523/JNEUROSCI.12-04-01454.1992
Dietzmann, 1994, Expression of P-glycoprotein as a multidrug resistance gene product in human reactive astrocytes and astrocytoma, Zentralblatt Pathologie, 140, 149
Divekar, 1971, Adenosine kinase of Sarcoma-180 cells. N6-substituted adenosines as substrates and inhibitors, Molec. Pharmac., 7, 663
Diverse-Pierluissi, 1991, Multiple actions of extracellular ATP on calcium currents in cultured bovine chromaffin cells, Proc. natl Acad. Sci. USA, 88, 1261, 10.1073/pnas.88.4.1261
Dragunow, 1990, Induction of c-fos mRNA and protein in neurons and glia after traumatic brain injury: pharmacological characterization, Exp. Neurol., 107, 236, 10.1016/0014-4886(90)90141-E
Drury, 1929, The physiological action of adenine compounds with special reference to their action on the mammalian heart, J. Physiol., 68, 214, 10.1113/jphysiol.1929.sp002608
Dunwiddie, 1985, The physiological role of adenosine in the central nervous system, Int. Rev. Neurobiol., 27, 63, 10.1016/S0074-7742(08)60556-5
Dusseau, 1988, Hypoxia-induced angiogenesis in chick chorioallantoic membranes: a role for adenosine, Respir. Physiol., 71, 33, 10.1016/0034-5687(88)90113-2
Dusseau, 1986, Stimulation of angiogenesis by adenosine on the chick chorioallantoic membrane, Circ. Res., 59, 163, 10.1161/01.RES.59.2.163
Eelles, 1983, Identification, development and regional distribution of ribonucleotide reductase in adult rat brain, J. Neurochem., 40, 1008, 10.1111/j.1471-4159.1983.tb08085.x
Enkvist, 1992, Activation of protein kinase C blocks astroglial gap junction communication and inhibits the spread of calcium waves, J. Neurochem., 59, 519, 10.1111/j.1471-4159.1992.tb09401.x
Erhardt, 1995, Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells, Mol. Cell. Biol., 15, 5524, 10.1128/MCB.15.10.5524
Eshleman, 1994, Release of dopamine via the human transporter, Molec. Pharmac., 45, 312
Ewing, 1993, Biliverdin reductase is heat resistant and coexpressed with constitutive and heat shock forms of heme oxygenase in brain, J. Neurochem., 61, 1015, 10.1111/j.1471-4159.1993.tb03615.x
de Felipe, 1993, The role of immediate early genes in the regeneration of the central nervous system, Adv. Neurol., 59, 263
Feuerstein, 1988, Activation of Al adenosine receptors decrease the release of serotonin in rabbit hippocampus, but not in the caudate nucleus, Naunyn-Schmiedeberg's Arch. Pharmac., 338, 664, 10.1007/BF00165632
Fischer, 1991, NGF improves spatial memory in aged rodents as a function of age, J. Neurosci., 11, 1889, 10.1523/JNEUROSCI.11-07-01889.1991
Fleysher, 1969, Synthesis and biological activity of some new N6-substituted purine nucleosides, J. Med. Chem., 12, 1056, 10.1021/jm00306a021
Folmar, 1980, The parr-smolt transformation (smoltification) and seawater adaptation in salmonids, Aqua-culture, 21, 1, 10.1016/0044-8486(80)90123-4
Foresta, 1992, Extracellular ATP is a trigger for the acrosome reaction in human spermatozoa, J. Biol. Chem., 26, 19443, 10.1016/S0021-9258(18)41795-4
Fox, 1978, The role of adenosine and 2-deoxyadenosine in mammalian cells, A. Rev. Biochem., 47, 655, 10.1146/annurev.bi.47.070178.003255
Franco, 1986, Heterogeneous localization of some purine enzymes in subcellular fractions of rat brain and cerebellum, Neurochem. Res., 11, 423, 10.1007/BF00965016
Frazer, 1979, Experimental angiogenesis in the chorioallantoic membrane, Bibl. Anat., 18, 25
Fredholm, 1995, Adenosine, adenosine receptors and the actions of caffeine, Pharmac. Toxic., 76, 93, 10.1111/j.1600-0773.1995.tb00111.x
Fredholm, 1988, How does adenosine inhibit neurotransmitter release?, Trends Pharmac. Sci., 9, 130, 10.1016/0165-6147(88)90194-0
Fredholm, 1979, Release of 3H-nucleotides from 3H-adenine labeled hypothalamic synaptosomes, Acta Physiol. Scand., 116, 285, 10.1111/j.1748-1716.1982.tb07142.x
Fredholm, 1994, Nomenclature and classification of purinoceptors, Pharmac. Rev., 46, 143
Frodin, 1994, Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells, J. biol. Chem., 269, 6207, 10.1016/S0021-9258(17)37589-0
Gailly, 1993, Post-receptor pathways of the ATP-induced relaxation in smooth muscle of the mouse vas deferens, Br. J. Pharmac., 110, 326, 10.1111/j.1476-5381.1993.tb13812.x
Ganassin, 1992, Effect of purine supplementation on the growth of salmonid cell lines in different mammalian sera, Cytotechnology, 8, 21, 10.1007/BF02540026
Ganassin, 1994, Enhancement of proliferation in cultures of Chinook salmon embryo cells by interactions between inosine and bovine sera, J. Cell. Physiol., 160, 409, 10.1002/jcp.1041600303
Gebicke-Harter, 1996, Both adenosine A1 and A2 receptors are required to stimulate microglial proliferation, Neurochem. Int., 29, 37, 10.1016/0197-0186(95)00137-9
Geffen, 1971, Synaptic vesicles in sympathetic neurons, Physiol. Rev., 51, 98, 10.1152/physrev.1971.51.1.98
Gemba, 1994, Glutamate efflux via the reversal of the sodium-dependent glutamate transporter caused by glycolytic inhibition in rat cultured astrocytes, Neuroscience, 63, 789, 10.1016/0306-4522(94)90523-1
Gerwins, 1992, ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol-1,4,5-triphosphate in smooth muscle cell line, J. biol. Chem., 267, 16081, 10.1016/S0021-9258(18)41969-2
Gille, 1992, Phosphorylation of transcription factor p62 TCF by MAP kinase stimulates ternary complex formation at c-fos promoter, Nature, 358, 414, 10.1038/358414a0
Giulian, 1989, The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain, J. Neurosci., 9, 4416, 10.1523/JNEUROSCI.09-12-04416.1989
Glasky, 1987, Isoprinosine (Inosine Pranobex BAN, INPX) in the treatment of AIDS and other acquired immunodeficiencies of clinical importance, Cancer Detec. Preven., 1, 597
Glasky, 1994, AIT-082 restores age-induced memory deficits and modulates neuritogenesis through a carbon monoxide/guanylate cyclase mechanism, IUPHAR, 72, 17.2.10
Glasky, 1995, A novel purine derivative AIT-082 increases synthesis of NGF, FGF-2 and NT-3 mRNA in astrocytes, Abstr. Soc. Neurosci., 21, 295
Glasky, 1996, Elevation of brain mRNA for neurotrophins by oral AIT-082 in mice, Abstr. Soc. Neurosci., 22, 751
Glaum, 1994, Inhibition of phosphoprotein phosphatases blocks metabotropic glutamate receptor effects in the rat nucleus solitarii, Molec. Pharmac., 45, 1221
Gnahn, 1983, NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain?, Brain Res., 285, 45, 10.1016/0165-3806(83)90107-4
Gordon, 1986, The hydrolysis of extracellular adenine nucleotides by cultured endothelial cells from pig aorta, J. biol. Chem., 261, 15496, 10.1016/S0021-9258(18)66740-7
Greene, 1976, Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to NGF, Proc. natl Acad. Sci. USA, 73, 2424, 10.1073/pnas.73.7.2424
Greene, 1982, PC12 pheochromocytoma cultures in neurobiological research, Adv. Cell. Neurobiol., 3, 373, 10.1016/B978-0-12-008303-9.50016-5
Griffiths, 1990, The role of adenosine in respiratory physiology, 381
Griffith, 1996, Nucleoside and nucleobase transport systems in mammalian cells, Biochim. Biophys. Acta, 1286, 153, 10.1016/S0304-4157(96)00008-1
Gu, 1995, Involvement of bidirectional adenosine transporters in the release of l-[3H]adenosine from rat brain synaptosomal. Preparations, J. Neurochem., 64, 2105, 10.1046/j.1471-4159.1995.64052105.x
Gubitz, 1996, Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals, J. Neurochem., 67, 374, 10.1046/j.1471-4159.1996.67010374.x
Gunning, 1981, Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells, J. cell. Biol., 89, 240, 10.1083/jcb.89.2.240
Guroff, 1981, The action of adenosine analogs on PC12 cells, J. Neurochem., 37, 1431, 10.1111/j.1471-4159.1981.tb06312.x
Gysbers, 1992, Guanosine and GTP enhance NGF stimulated neurite outgrowth in PC12 cells, Abstr. Soc. Neurosci., 18, 1000
Gysbers, 1992, Guanosine enhances NGF-stimulated neurite outgrowth in PC12 cells, Neuroreport, 3, 997, 10.1097/00001756-199211000-00013
Gysbers, 1996, GTP and guanosine synergistically enhance NGF-induced neurite outgrowth from PC12 cells, Int. J. Dev. Neurosci., 14, 19, 10.1016/0736-5748(95)00083-6
Gysbers, 1996, Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms, Neurosci. Lett., 47, 427
Gysbers, 1994, Extracellular guanosine and GTP stimulate NGF and FGF-2 synthesis by astrocytes, Abstr. Soc. Neurosci., 20, 1314
Gysbers, 1996, Extracellular GTP increases intracellular calcium in PC12 cells, Abstr. Soc. Neurosci., 23, 737
Haas, 1988, Endogenous adenosine inhibits hippocampal CAI neurones: further evidence from extra- and intracellular recordings, Naunyn-Schmiedeberg's Arch. Pharmac., 337, 561, 10.1007/BF00182732
Hagberg, 1987, Extracellular adenosine, inosine, hypoxanthine and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia, J. Neurochem., 49, 227, 10.1111/j.1471-4159.1987.tb03419.x
Harden, 1995, P2-Purinergic receptors: subtype-associated signaling responses and structure, A. Rev. Pharmac. Toxic., 35, 541, 10.1146/annurev.pa.35.040195.002545
Harkness, 1988, Hypoxanthine, xanthine and uridine in body fluids, indicators of ATP depletion, J. Chromatography, 429, 255, 10.1016/S0378-4347(00)83873-6
Hayashi, 1993, Role of metabotropic glutamate receptors in synaptic modulation in the accessory olfactory bulb, Nature, 366, 687, 10.1038/366687a0
Heese, 1997, Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a receptors, Neurosci. Lett., 231, 83, 10.1016/S0304-3940(97)00545-4
Heilbronn, 1995, 5′-Nucleotidase activates and an inhibitory antibody prevents neuritic differentiation of PC12 cells, Eur. J. Neurosci., 7, 1172, 10.1111/j.1460-9568.1995.tb01107.x
Henning, 1993, Characterization of P2-purinoceptor mediated cyclic AMP formation in mouse C2C12 myotubes, Br. J. Pharmac., 110, 133, 10.1111/j.1476-5381.1993.tb13782.x
Herman, 1993, Purine nucleoside uptake by mouse brain astrocytes, Abstr. Soc. Neurosci., 19, 59
Herman, 1994, Responses to cAMP depend on stage of neuronal differentiation of NGF-treated adrenal chromaffin cells, Dev. Biol., 161, 477, 10.1006/dbio.1994.1046
Hindley, 1994, Nitric oxide and carbon monoxide enhance neurite outgrowth from PC12 cells by activating soluble guanylate cyclase. IUPHAR Satellite Meeting. Nitric oxide in the Nervous System, Neuropharmacology, 11, 140
Hindley, 1994, Stimulation of reactive astrogliosis in vivo by extracellular ADP or an adenosine A2 receptor agonist, J. Neurosci. Res., 38, 399, 10.1002/jnr.490380405
Hindley, 1997, Nitric oxide donors enhance neurotrophin-induced neurite outgrowth through a cGMP-dependent mechanism, J. Neurosci. Res., 47, 427, 10.1002/(SICI)1097-4547(19970215)47:4<427::AID-JNR8>3.0.CO;2-G
Ho, 1996, A novel P2-purinoceptor expressed by a subpopulation of astrocytes from the dorsal spinal cord of the rat, Br. J. Pharmac., 116, 2909, 10.1111/j.1476-5381.1995.tb15944.x
Hoehn, 1990, Role of excitatory amino acid receptors in K+- and glutamate-evoked release of endogenous adenosine from rat cortical slices, J. Neurochem., 54, 256, 10.1111/j.1471-4159.1990.tb13309.x
Hoffaker, 1984, Adenosine inhibits cell division and promotes neurite extension in PC12 cells, J. cell. Physiol., 120, 188, 10.1002/jcp.1041200212
Holmsen, 1987, Platelet secretion, 606
Huttemann, 1984, Ra adenosine receptors in human platelets. Characterization by 5′-N-ethylcarboxamido-[3H]-adenosine binding in relation to adenylate cyclase activity, Naunyn-Schimedeberg's Arch. Pharmac., 325, 226
Ikeda, 1995, Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: subtype-specific coupling to ion channel, Neuron, 14, 1029, 10.1016/0896-6273(95)90341-0
Imre, 1964, Studies on the mechanism of retinal neovascularization, Br. J. Ophthalmol., 48, 75, 10.1136/bjo.48.2.75
Ingerman, 1979, Direct measurement of platelet secretion in whole blood, Thromb. Res., 16, 335, 10.1016/0049-3848(79)90081-1
Ingi, 1995, Direct demonstration of a physiological role for carbon monoxide in olfactory receptor neurons, J. Neurosci., 15, 8214, 10.1523/JNEUROSCI.15-12-08214.1995
Jackish, 1985, Adenosine: an endogenous modulator of hippocampal noradrenaline release, Neuropharmacology, 24, 499, 10.1016/0028-3908(85)90055-3
James, 1993, Production of adenosine from extracellular ATP at the striatal cholinergic synapse, J. Neurochem., 60, 219, 10.1111/j.1471-4159.1993.tb05841.x
Jarvis, 1990, Adenosine in central nervous system function, 423
Johnston, 1989, Sodium-dependent uptake of nucleosides by dissociated brain cells from the rat, J. Neurochem., 52, 75, 10.1111/j.1471-4159.1989.tb10900.x
Jonzon, 1985, Release of purines, noradrenaline and GABA from rat hippocampal slices by field stimulation, J. Neurochem., 44, 217, 10.1111/j.1471-4159.1985.tb07133.x
Joseph, 1993, Neuronal death: cytoplasmic calcium and internucleosom al DNA fragmentation: evidence for DNA fragments being released from cells, Mol. Brain Res., 17, 70, 10.1016/0169-328X(93)90074-Y
Junard, 1990, Long-term administration of mouse nerve growth factor to adult rats with partial lesions of the cholinergic septohippocampal pathway, Exp. Neurol., 110, 25, 10.1016/0014-4886(90)90048-W
Juurlink, 1998, The hypoxanthine derivative AIT-082 promotes neurite formation and regeneration in cultured hippocampal neurons, Abstr. Soc. Neurosci., 24, 1941
Karkos, 1990, Purinergic neuromodulation, Fortschr. Neurol. Psychiatr., 58, 33, 10.1055/s-2007-1001168
Kastritsis, 1992, Stimulation of the P2Y purinergic receptor on type 1 astroglia results in inositol phosphate formation and calcium mobilization, J. Neurochem., 58, 1277, 10.1111/j.1471-4159.1992.tb11339.x
Keller, 1983, Ecto-adenosine triphosphate activity at the cholinergic nerve endings of the Torpedo electric organ, Life Sci., 33, 2635, 10.1016/0024-3205(83)90347-8
Kennedy, 1994, Adenosine and ATP: from receptor structure to clinical. applications, Trends Pharmac. Sci., 15, 311, 10.1016/0165-6147(94)90018-3
Kerr, 1972, Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics, Br. J. Cancer, 26, 239, 10.1038/bjc.1972.33
Kim, 1991, Purinergic stimulation of astroblast proliferation: guanosine and its nucleotides stimulate cell division in chick astroblasts, J. Neurosci. Res., 28, 442, 10.1002/jnr.490280318
Kimelberg, 1995, Astrocytic swelling due to hypotonic or high K+ medium causes inhibition of glutamate and aspartate uptake and increases their release, J. Cereb. Blood Flow Metab., 15, 409, 10.1038/jcbfm.1995.51
Kinlough-Rathbone, 1987, Endogenous mediators of platelet activation, Vol. III, 239
Kitazono, 1989, Involvement of calcium and protein kinase C in the activation of the Na+/H+ exchanger in cultured bovine aortic endothelial cells stimulated by extracellular ATP, Biochem. Biophys. Acta, 101.3, 152, 10.1016/0167-4889(89)90043-8
Kittner, 1997, Clinical trials in dementia with propentofylline, Ann. N.Y. Acad. Sci., 826, 307, 10.1111/j.1749-6632.1997.tb48481.x
Knopfel, 1995, Metabotropic glutamate receptors: novel targets for drug development, J. med. Chem., 38, 1417, 10.1021/jm00009a001
Knudsen, 1987, Evidence for negative control of growth by adenosine in the mammalian embryo Induction of Hmx/+ mutant limb outgrowth by adenosine deaminase, Differentiation, 33, 270, 10.1111/j.1432-0436.1987.tb01567.x
Kohno, 1996, Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A3 receptor agonists, Biochem. biophys. Res. Commun., 219, 904, 10.1006/bbrc.1996.0331
Kostyuk, 1994, Calcium stores in neurons and glia, Neuroscience, 63, 381, 10.1016/0306-4522(94)90537-1
Krishtal, 1988, Cation channels activated by extracellular ATP in rat sensory neurons, Neuroscience, 27, 995, 10.1016/0306-4522(88)90203-5
Kulkarni, 1996, Quantitative analysis of similarities and differences in neurotoxicities caused by adenosine and 2-deoxyadenosine in sympathetic neurons, J. Neurochem., 67, 778, 10.1046/j.1471-4159.1996.67020778.x
Lai, 1991, Metabolism of extracellular adenine nucleotides by cultured rat brain astrocytes, J. Neurochem., 57, 1510, 10.1111/j.1471-4159.1991.tb06345.x
Langercrantz, 1976, On the composition and function of large dense core vesicles in sympathetic nerves, Neuroscience, 1, 81, 10.1016/0306-4522(76)90002-6
Latini, 1996, A2 adenosine receptors: their presence and neuromodulatory role in the central nervous system, Gen. Pharmac., 27, 925, 10.1016/0306-3623(96)00044-4
Laurenssen, C. M., Middlemiss, P. J. and Rathbone, M. P. (1991) The role of purine nucleosides in the response of brain and other tissues to injury: I. Mechanism of action of guanosine, adenosine metabolites and deoxynucleosides and nucleotides. In: Abstracts of the 10th Annual Marcus Singer Symposium for Regeneration and Limb Development, p. 10 (No. 8).
Lazarowski, 1994, Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C, J. biol. Chem., 269, 11830, 10.1016/S0021-9258(17)32648-0
Lee, 1988, Kinetic and inhibitor specificity of adenosine transport in guinea pig cerebral cortical synaptosome: evidence for two nucleoside transporters, Neurochem. Int., 12, 483, 10.1016/0197-0186(88)90032-0
Lewin, 1992, On the role of nerve growth factor in the development of myelinated nociceptors, J. Neurosci., 12, 96
Lewin, 1993, Nerve growth factor-induced hyperalgesia in the neonatal and adult sensory neurons, Neuroscience, 13, 2136, 10.1523/JNEUROSCI.13-05-02136.1993
Lillien, 1985, Nerve growth factor is a mitogen for cultured chromaffin cells, Nature, 317, 632, 10.1038/317632a0
Linden, 1994, Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions, Trends Pharmac. Sci., 15, 298, 10.1016/0165-6147(94)90011-6
Lindsay, 1986, Reactive astrogliosis, Vol. 3, 231
Lloyd, 1995, Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices, Neurochem. Int., 26, 387, 10.1016/0197-0186(94)00144-J
Lloyd, 1993, Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation and energy depletion, Neurochem. Int., 23, 173, 10.1016/0197-0186(93)90095-M
Londos, 1980, Subclasses of external adenosine receptors, Proc. natl Acad. Sci. USA, 77, 2551, 10.1073/pnas.77.5.2551
MacDonald, 1985, Nature of extrasynaptosomal accumulation of endogenous adenosine evoked by K and veratridine, J. Neurochem., 45, 791, 10.1111/j.1471-4159.1985.tb04062.x
Maire, 1984, Release of adenosine, inosine and hypoxanthine from rabbit non-myelinated nerve fibres at rest and during activity, J. Physiol., 357, 67, 10.1113/jphysiol.1984.sp015489
Marks, 1991, Does carbon monoxide have a physiological function?, Trends Pharmac. Sci., 12, 185, 10.1016/0165-6147(91)90544-3
Marshall, 1995, Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated activation, Cell, 80, 179, 10.1016/0092-8674(95)90401-8
Martin, 1992, Synthesis and release of neuroactive substances by glial cells, GLIA, 5, 81, 10.1002/glia.440050202
Matsumoto, 1992, Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia, Brain Res., 579, 309, 10.1016/0006-8993(92)90066-I
McAuslan, 1983, Angiogenic factors and their assay: activity of formyl methionyl leucyl phenylalanine, adenosine diphosphate, heparin, copper and bovine endothelium stimulating factor, Microvas. Res., 26, 323, 10.1016/0026-2862(83)90080-8
McGeer, 1987, Other heterocyclic putative neurotransmitters: histamine and purines, 349
Meghji, 1989, Adenosine formation and release by embryonic chick neurons and glia in cell culture, J. Neurochem., 52, 1852, 10.1111/j.1471-4159.1989.tb09252.x
Meininger, 1990, Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells, In Vitro Cell. Dev. Biol., 28A, 529
Meininger, 1988, Adenosine and hypoxia stimulate proliferation and migration of endothelial cells, Am. J. Physiol., 255, H554
Meldrum, 1990, Excitatory amino acid neurotoxicity and neurodegenerative disease, Trends Neurosci., 11, 379
Middlemiss, P. T., Rathbone, M. P. and Hooftman, E. (1990) Purinergic stimulation of astrocyte proliferation: evidence for involvement of P1-A2 and P2Y receptors. In: Abstracts of the Canadian College of Neuropsychopharmacology, p. 23 (No. 7).
Middlemiss, 1995, AIT-082, a unique purine derivative, enhances nerve growth factor mediated neurite outgrowth from PC12 cells, Neurosc. Lett., 199, 131, 10.1016/0304-3940(95)12029-4
Middlemiss, 1995, Extracellular guanosine and guanosine-5′-triphosphate increase NGF synthesis and release from cultured mouse neopallial astrocytes, Brain Res., 677, 152, 10.1016/0006-8993(95)00156-K
Mitchell, 1993, Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus, Neuroscience, 13, 3439, 10.1523/JNEUROSCI.13-08-03439.1993
Miyamoto, 1982, Guanine deaminase from rat brain. Purification, characteristics and contribution to ammoniagenesis in the brain, J. Biochem., 91, 167, 10.1093/oxfordjournals.jbchem.a133673
Miyashita, 1984, Receptor mechanisms in fish chromatophores—IV. Adenosine receptors mediate pigment dispersion in guppy and catfish melanophores, Comp. Biochem. Physiol., 77C, 471
Morgan, 1987, Mapping patterns of c-fos expression in the central nervous system after seizure, Science, 237, 192, 10.1126/science.3037702
Murphy, 1991, Adenosine-dependent regulation of cyclic AMP accumulation in primary cultures of rat astrocytes and neurons, J. Neurosci. Res., 30, 631, 10.1002/jnr.490300406
Nabeshuma, 1994, Oral administration of NGF synthesis stimulators recovers reduced brain NGF content in aged rats and cognitive dysfunction in basal-forebrain-lesioned rats, Gerontology, 40, 46, 10.1159/000213627
Nagy, 1983, Adenosine triphosphate activity at the external surface of chicken brain synaptosomes, J. Neurochem., 40, 226, 10.1111/j.1471-4159.1983.tb12675.x
Nagy, 1986, Ecto-ATPase of mammalian synaptosomes. Identification and enzymic characterization, J. Neurochem., 47, 976, 10.1111/j.1471-4159.1986.tb00707.x
Nagy, 1989, Rat brain synaptosomal ATP:AMP-phosphotransferase activity, J. Neurochem., 53, 1166, 10.1111/j.1471-4159.1989.tb07410.x
Nakanishi, 1992, Molecular diversity of glutamate receptors and implications for brain function, Science, 258, 597, 10.1126/science.1329206
Neary, 1994, Signaling by ATP receptors in astrocytes, Neuroreport, 5, 1617, 10.1097/00001756-199408150-00019
Neary, 1988, ATP stimulates calcium influx in primary astrocyte cultures, Biochem. biophys. Res. Commun., 157, 1410, 10.1016/S0006-291X(88)81032-5
Neary, 1991, ATP-evoked calcium signal stimulates protein phosphorylation/dephosphorylation in astrocytes, Brain Res., 566, 89, 10.1016/0006-8993(91)91684-S
Neary, 1996, Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells, Trends Neurosci., 19, 13, 10.1016/0166-2236(96)81861-3
Needham, 1988, Endothelial cell functional response and increased vascular permeability induced by polycations, Lab. Invest., 59, 538
Nicoletti, 1996, Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?, Trends Pharmac. Sci., 19, 267
Nitta, 1994, Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats, Naunyn-Schmiedeberg's Arch. Pharmac., 349, 401, 10.1007/BF00170887
Norton, 1992, Quantitative aspects of reactive astrogliosis: a review, Neurochem. Res., 17, 877, 10.1007/BF00993263
Novales, 1970, A melanin-dispersing effect of cyclic adenosine monophosphate on Fundulus melanophores, J. cell. Physiol., 75, 133, 10.1002/jcp.1040750116
O'Regan, 1992, The selective adenosine receptor agonist CGS 21680 enhances excitatory amino acid release from the ischemic rat cerebral cortex, Neurosci. Lett., 138, 169, 10.1016/0304-3940(92)90498-V
Ogata, 1995, A possible mechanism for the hypoxia-hypoglycemia-induced release of excitatory amino acids from cultured hippocampal astrocyte, Neurochem. Res., 20, 737, 10.1007/BF01705543
Ogata, 1996, Potentiated cAMP rise in metabotropically stimulated rat cultured astrocytes by a Ca2+-related A1/A2 adenosine receptors cooperation, Eur. J. Neurosci., 8, 1124, 10.1111/j.1460-9568.1996.tb01280.x
Olah, 1990, Adenosine receptor subtpes: characterization and therapeutic regulation, A. Rev. Pharmac. Toxic., 35, 581, 10.1146/annurev.pa.35.040195.003053
Oppenheim, 1991, Cell death during development of the nervous system, A. Rev. Neurosci., 14, 453, 10.1146/annurev.ne.14.030191.002321
Orrenius, 1995, Apoptosis: molecular mechanisms and implications for human disease, J. Internal Med., 237, 529, 10.1111/j.1365-2796.1995.tb00881.x
Palmer, 1995, Review. Neurotransmitter receptors, VII. Adenosine receptors, Neuropharmacology, 34, 683, 10.1016/0028-3908(95)00044-7
Pardridge, 1997, Brain microvascular and astrocyte localization of p-glycoprotein, J. Neurochem., 68, 1278, 10.1046/j.1471-4159.1997.68031278.x
Pasantes-Morales, 1990, Volume-sensitive release of taurine from cultured astrocytes: Properties and mechanism, GLIA, 3, 427, 10.1002/glia.440030514
Patterson, 1992, Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in Ca2+ evokes increases in BDNF and NT-3 mRNAs, Neuron, 9, 1081, 10.1016/0896-6273(92)90067-N
Pearce, 1987, Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells, FEBS Lett., 223, 143, 10.1016/0014-5793(87)80525-2
Pearce, 1989, ATP-evoked Ca2+ mobilization and prostanoid release from astrocytes: P2-purinergic receptors linked to phosphoinositide hydrolysis, J. Neurochem., 52, 971, 10.1111/j.1471-4159.1989.tb02549.x
Pearson, 1979, Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides, Nature, 281, 384, 10.1038/281384a0
Pechan, 1993, Glutamate induces the growth factors NGF, bFGF, the receptor FGF-RI and c-fos mRNA expression in rat astrocyte culture, Neurosci. Lett., 153, 111, 10.1016/0304-3940(93)90089-4
Peraldi, 1995, Regulation of the MAP kinase cascade in PC12 cells: B-Raf activates MEK-1 (MAP kinase or ERK kinase) and is inhibited by cAMP, FEBS Lett., 357, 290, 10.1016/0014-5793(94)01376-C
Phillis, 1991, Brain adenosine and transmitter amino acid release from the ischemic rat cerebral cortex: effects of the adenosine deaminase inhibitor deoxycoformycin, J. Neurochem., 56, 644, 10.1111/j.1471-4159.1991.tb08198.x
Pin, 1995, The metabotropic glutamate receptors structure and functions, Neuropharmacology, 34, 1, 10.1016/0028-3908(94)00129-G
Pintor, 1992, Presence of diadenosine polyphosphates-Ap4A and Ap5A-in rat brain synaptic terminals. Ca2+ dependent release evoked by 4-aminopyridine and veratridine, Neurosci. Lett., 136, 141, 10.1016/0304-3940(92)90034-5
Porter, 1995, Adenosine receptors modulate [Ca2+]i in hippocampal astrocytes in situ, J. Neurochem., 65, 1515, 10.1046/j.1471-4159.1995.65041515.x
Pulverer, 1991, Phosphorylation of c-jun mediated by MAP kinases, Nature, 353, 670, 10.1038/353670a0
Pyke, K. (1972) The induction of maturation in neuroblastoma. MSc Thesis, McMaster University, Hamilton, Ontario, Canada.
Ramirez, 1998, The effects of AIT-082 on septodentate sprouting after unilateral entorhinal cortex lesions in the rat, Drug Dev. Res., 43, 58
Rathbone, 1972, Metabolism and biological effects of N6-(2-isopentenyl)-adenosine on a cell line derived from circulating leukocytes of a patient with chronic myelogenous leukemia, Cancer Res., 32, 1647
Rathbone, 1993, Hippocampal neurons in vitro respond to extracellular guanosine and GTP with neurite outgrowth and branching, Abstr. Soc. Neurosci., 19, 88
Rathbone, M. P., Middlemiss, P. J. and Kim, J.-K. 1990a. Purine nucleosides and nucleotides stimulate proliferation of serum starved astrocytes in tissue culture. In: Abstracts of the 4th Canadian Neuro-Oncology Meeting, p. 16 (No. 5).
Rathbone, 1990, Stimulation of astrocyte proliferation by purine nucleosides and nucleotides through A2 and purine P2Y receptors, Abstr. Soc. Neurosci., 16, 1000
Rathbone, 1990, Stimulation of astrocyte proliferation by picomolar concentrations of purine nucleotides: implications for neural development, Abstracts of the 8th Biennial Meeting, International Society for Developmental Neuroscience, 8, 115
Rathbone, 1991, Purine nucleosides and nucleotides stimulate astrocyte proliferation in vitro and astrogliosis in vivo, Abstr. Soc. Neurosci., 17, 550
Rathbone, 1991, Extracellular guanosine increases astrocyte cAMP: inhibition by adenosine A2 antagonists, Neuroreport, 2, 661, 10.1097/00001756-199111000-00007
Rathbone, 1992, Extracellular purine nucleosides stimulate cell division and morphogenesis: pathological and physiological implications, Med. Hypotheses, 37, 232, 10.1016/0306-9877(92)90193-G
Rathbone, 1992, Purinergic stimulation of cell division and differentiation: mechanisms and pharmacological implications, Med. Hypotheses, 37, 213, 10.1016/0306-9877(92)90190-N
Rathbone, 1992, Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types, In Vitro Cell. Dev. Biol., 28A, 529, 10.1007/BF02634137
Rathbone, 1992, Adenosine and its nucleotides stimulate proliferation of chick astroblasts and human astrocytoma cells, Neurosci. Res., 13, 1, 10.1016/0168-0102(92)90030-G
Rathbone, 1997, Effects of guanosine and 2-chloroadenosine on C6 glioma cell growth, Abstr. Soc. Neurosci., 23, 71
Rathbone, 1998, The trophic effects of purines and purinergic signaling in pathogenic reactions of astrocytes, Alzheimer Dis. Assoc. Disord., 12, S36, 10.1097/00002093-199803001-00006
Recklies, 1974, Stimulation of nerve fiber growth from cultured sympathetic explants, Can. J. Physiol. Pharmac., 52, 840, 10.1139/y74-109
Redzic, 1998, Endogenous nucleosides in the guinea-pig eye: analysis of transport and metabolites, Exp. Eye Res., 66, 315, 10.1006/exer.1997.0424
Ribeiro, 1995, Purinergic inhibition on neurotransmitter release in the central nervous system, Pharmac. Toxic., 77, 299, 10.1111/j.1600-0773.1995.tb01031.x
Richardson, 1987, ATP release from affinity-purified rat cholinergic nerve terminals, J. Neurochem., 48, 622, 10.1111/j.1471-4159.1987.tb04138.x
Richter-Landsberg, 1986, The role of cAMP in nerve growth factor-promoted neurite outgrowth in PC12 cells, J. Cell. Biol., 102, 821, 10.1083/jcb.102.3.821
Rudge, 1993, Astrocyte-derived neurotrophic factors, 267
Rudolphi, 1992, Neuroprotective role of adenosine in cerebral ischemia, Trends Pharmac. Sci., 13, 439, 10.1016/0165-6147(92)90141-R
Rusanescu, 1995, Calcium influx induces neurite outgrowth through a Src-Ras signaling cassette, Neuron, 15, 1415, 10.1016/0896-6273(95)90019-5
Salter, 1995, ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord, J. Neurosci., 15, 2961, 10.1523/JNEUROSCI.15-04-02961.1995
Scheimann, 1991, ATP causes release of intracellular Ca2+ via the phosphoinositide metabolism in pregnant guinea pig myometrium, Am. J. Physiol., 261, E665
Schwartz, 1990, Beta-adrenergic receptor regulation, through cyclic AMP, of nerve growth factor expression in rat cortical and cerebellar astrocytes, Cell. mol. Neurobiol., 10, 447, 10.1007/BF00711186
Sei, 1997, Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons, Drug Dev. Res., 40, 267, 10.1002/(SICI)1098-2299(199703)40:3<267::AID-DDR7>3.0.CO;2-I
Sevigny, 1995, Purification of pancreas type-I ATP diphosphohydrolase and identification with the 5′-p-fluorosulphonylbenzoyladenosine ATP analogue, Biochem. J., 312, 351, 10.1042/bj3120351
Shinoda, 1990, Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells, Biochem. Pharmac., 39, 1813, 10.1016/0006-2952(90)90130-D
Shinozaki, 1994, Neuron damage induced by some potent kainoids and neuroprotective action of new agonists for metabotropic glutamate receptors, Eur. Neurol., 34, 2, 10.1159/000119534
Si, 1996, Adenosine and propentofylline inhibit the proliferation of cultured microglial cells, Exp. Neurol., 137, 345, 10.1006/exnr.1996.0035
Silinsky, 1975, On the association between transmitter secretion and release of adenine nucleotides from mammalian motor nerve terminals, J. Physiol., 247, 145, 10.1113/jphysiol.1975.sp010925
Silinsky, 1984, On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings, J. Physiol., 346, 243, 10.1113/jphysiol.1984.sp015019
Slocum, 1972, N6-(△-isopentenyl) adenosine (IPAdo); uptake, metabolism, and site of action in Sarcoma-180 cells (S-180), Proc. Am. Ass. Cancer Res., 13, 70
Smuts, 1981, Rapid nasal pit formation in mouse embryos stimulated by ATP-containing medium, J. exp. Zoo., 216, 409, 10.1002/jez.1402160309
de Souza, 1991, The involvement of ecto-ATPase activity in the phosphorylation of intracellular proteins by the addition of extracellular [32P]ATP in PC12 cells, Neurochem. Int., 19, 581, 10.1016/0197-0186(91)90079-S
de Souza, 1995, Purine and pyrimidine nucleotides activate distinct signalling pathways in PC12 cells, J. Neurosci. Res., 41, 753, 10.1002/jnr.490410606
Sperlagh, 1995, ATP acts as fast neurotransmitter in rat habenula: neurochemical and enzyme cytochemical evidence, Neuroscience, 66, 915, 10.1016/0306-4522(94)00588-V
Spranger, 1990, Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo, Eur. J. Neurosci., 2, 69, 10.1111/j.1460-9568.1990.tb00382.x
Surprenant, 1996, The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P), Science, 272, 735, 10.1126/science.272.5262.735
Szatkowski, 1994, Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms, Trends Neurosci., 17, 359, 10.1016/0166-2236(94)90040-X
Szeberenyi, 1994, Cellular components of nerve growth factor signaling, Biochem. Biophys. Acta, 1222, 187, 10.1016/0167-4889(94)90168-6
Szondy, 1994, Adenosine stimulates DNA fragmentation in human thymocytes by Ca2+-mediated mechanisms, Biochem. J., 396, 877, 10.1042/bj3040877
Tanabe, 1992, A family of metabotropic glutamate receptors, Neuron, 8, 169, 10.1016/0896-6273(92)90118-W
Terrian, 1989, ATP release, adenosine formation and modulation of dynorphin and glutamic acid release by adenosine analogues in rat hippocampal mossy fiber synaptosomes, J. Neurochem., 53, 1390, 10.1111/j.1471-4159.1989.tb08529.x
Thompson, 1995, Apoptosis in the pathogenesis and treatment of disease, Science, 267, 1456, 10.1126/science.7878464
Todorov, 1994, Inhibitory and facilitatory effects of purines on transmitter release from sympathetic nerves, J. Pharmac. exp. Ther., 268, 985
Toms, 1996, Latest eruptions in metabotropic glutamate receptors, Trends Pharmac. Sci., 17, 429, 10.1016/S0165-6147(96)01006-1
Trams, 1974, On the sidedness of plasma membrane enzymes, Biochim. Biophys. Acta, 345, 180, 10.1016/0005-2736(74)90257-0
Uemura, 1991, Neurochemical analysis of focal ischemia in rats, Stroke, 22, 1548, 10.1161/01.STR.22.12.1548
Van Wylen, 1986, Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia, J. Cerebral Blood Flow Metab., 6, 522, 10.1038/jcbfm.1986.97
Verma, 1993, Carbon monoxide: a putative neural messenger, Science, 259, 381, 10.1126/science.7678352
Wagner, 1978, Chemical and physical characterization of cholinergic synaptic vesicles, Biochemistry, 17, 1199, 10.1021/bi00600a010
Wang, 1997, Functional and molecular characteristics of Na-dependent nucleoside transporters, Pharmac. Res., 14, 1524, 10.1023/A:1012113931332
White, 1977, Direct detection of depolarization-induced release of ATP from synaptosomal preparation, Nature, 267, 67, 10.1038/267067a0
White, 1978, Release of ATP from a synaptosomal preparation by elevated extracellular K and by veratridine, J. Neurochem., 30, 329, 10.1111/j.1471-4159.1978.tb06534.x
Wieraszko, 1989, Stimulation-dependent release of adenosine triphosphate from hippocampal slices, Brain Res., 3, 244, 10.1016/0006-8993(89)90567-2
Williams, 1986, Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection, Proc. natl Acad. Sci. USA, 83, 9231, 10.1073/pnas.83.23.9231
Williams, 1984, Adenosine a selective neuromodulator in the mammalian CNS?, Trends Neurosci., 7, 164, 10.1016/S0166-2236(84)80129-0
Wojcik, 1983, Location of adenosine release and adenosine A2 receptors to rat striatal neurons, Life Sci., 33, 755, 10.1016/0024-3205(83)90781-6
Wu, 1997, Presynaptic inhibition of elicited neurotransmitter release, Trends Neurosci., 20, 204, 10.1016/S0166-2236(96)01015-6
Wu, 1978, Distribution and release of adenosine triphosphate in rat brain, Neurochem. Res., 3, 563, 10.1007/BF00963759
Yao, 1997, Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists, Biochem. biophys. Res. Commun., 3232, 317, 10.1006/bbrc.1997.6290
Yeung, 1986, Temporary inhibition of the initiation of motility of demembranated hamster sperm by high concentrations of ATP, Int. J. Androl., 9, 359, 10.1111/j.1365-2605.1986.tb00898.x
Yoon, 1991, Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus, J. Neurosci., 11, 1375, 10.1523/JNEUROSCI.11-05-01375.1991
Yoshida, 1992, Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astocytes by fibroblast growth factor and other cytokines, Brain Res., 569, 14, 10.1016/0006-8993(92)90364-F
Zetterstrom, 1990, Adenosine agonists can both inhibit and enhance in vivo striatal dopamine release, Eur. J. Pharmac., 180, 137, 10.1016/0014-2999(90)90601-2
Zetterstrom, 1982, Purine levels in the intact brain. Studies with an implanted perfused hollow fiber, Neurosci. Lett., 29, 111, 10.1016/0304-3940(82)90338-X
Zhang, 1988, ATP secretion and extracellular protein phosphorylation by CNS neurons in primary culture, Brain Res. Bull., 21, 459, 10.1016/0361-9230(88)90159-1
Zheng, 1991, Extracellular ATP as a trigger for apoptosis or programmed cell death, J. Cell. Biol., 112, 279, 10.1083/jcb.112.2.279
Ziche, 1982, Role of prostaglandin El and copper in angiogenesis, J. natl Cancer Inst., 69, 475
Ziegler, 1981, Differential effects of cyclic AMP and cholera toxin on nerve growth factor from adrenal medullary chromaffin and pheochromocytoma cells, Brain Res., 227, 622, 10.1016/0165-3806(81)90014-6
Zimmerman, 1996, Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system, Prog. Neurobiol., 49, 589, 10.1016/0301-0082(96)00026-3
Zimmermann, 1996, The roles of 5′-nucleotidase in the nervous system, Drug Dev. Res., 37, 138
Zoeteweij, 1992, Involvement of intracellular Ca2+ and K+ in dissipation of the mitochondrial membrane potential and cell death induced by extracellular ATP in hepatocytes, Biochem. J., 288, 207, 10.1042/bj2880207