Triglyceride Mobilization from Lipid Droplets Sustains the Anti-Steatotic Action of Iodothyronines in Cultured Rat Hepatocytes
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bell, 2008, Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance, Diabetes, 57, 2037, 10.2337/db07-1383
Bickel, 2009, PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores, Biochim. Biophys. Acta, 1791, 419, 10.1016/j.bbalip.2009.04.002
Boveris, 1973, The mitochondrial generation of hydrogen peroxide. General properties and the effect of hyperbaric oxygen, Biochem. J., 134, 707, 10.1042/bj1340707
Cavallo, 2013, 3,5-Diiodo-L-thyronine administration to hypothyroid rats rapidly enhances fatty acid oxidation rate and bioenergetic parameters in liver cells, PLoS ONE, 8, e52328, 10.1371/journal.pone.0052328
Crunk, 2013, Dynamic regulation of hepatic lipid droplet properties by diet, PLoS ONE, 8, e67631, 10.1371/journal.pone.0067631
de Lange, 2011, Nonthyrotoxic prevention of diet-induced insulin resistance by 3,5-diiodo-L-thyronine in rats, Diabetes, 60, 2730, 10.2337/db11-0207
Fugassa, 1983, RNA synthesis in primary cultures of adult rat hepatocytes, In vitro, 19, 299, 10.1007/BF02619508
Goldberg, 2012, Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway, Endocrinology, 153, 5143, 10.1210/en.2012-1572
Grasselli, 2008, Effects of 3,5-diiodo-L-thyronine administration on the liver of high fat diet-fed rats, Exp. Biol. Med. (Maywood.), 233, 549, 10.3181/0710-RM-266
Grasselli, 2011a, Direct effects of iodothyronines on excess fat storage in rat hepatocytes, J. Hepatol., 54, 1230, 10.1016/j.jhep.2010.09.027
Grasselli, 2011b, Non-receptor-mediated actions are responsible for the lipid-lowering effects of iodothyronines in FaO rat hepatoma cells, J. Endocrinol., 210, 59, 10.1530/JOE-11-0074
Grasselli, 2012, 3,5-Diiodo-L-thyronine modulates the expression of genes of lipid metabolism in a rat model of fatty liver, J. Endocrinol., 212, 149, 10.1530/JOE-11-0288
Grasselli, 2010, PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids, Int. J. Mol. Med., 25, 505, 10.3892/ijmm_00000370
Iguchi, 1993, Lipid peroxidation and disintegration of the cell membrane structure in cultures of rat lung fibroblasts treated with asbestos, J. Appl. Toxicol., 13, 269, 10.1002/jat.2550130409
Khor, 2013, Lipid droplet metabolism, Curr. Opin. Clin. Nutr. Metab. Care, 16, 632, 10.1097/MCO.0b013e3283651106
Kimmel, 2010, Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins, J. Lipid. Res., 51, 468, 10.1194/jlr.R000034
Kiss, 2014, Rab proteins implicated in lipid storage and mobilization, J. Biomed. Res., 28, 169, 10.7555/JBR.28.20140029
Koopman, 2001, Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids, Histochem. Cell Biol., 116, 63, 10.1007/s004180100297
Laemmli, 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0
Lanni, 2005, 3,5-diiodo-L-thyronine powerfully reduces adiposity in rats by increasing the burning of fats, FASEB J., 19, 1552, 10.1096/fj.05-3977fje
Lombardi, 1998, Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus, Biochem. J., 330, 521, 10.1042/bj3300521
Mangiullo, 2010, 3,5-diiodo-L-thyronine upregulates rat-liver mitochondrial F(o)F(1)-ATP synthase by GA-binding protein/nuclear respiratory factor-2, Biochim. Biophys. Acta, 1797, 233, 10.1016/j.bbabio.2009.10.009
Mollica, 2009, 3,5-diiodo-l-thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet, J. Hepatol., 51, 363, 10.1016/j.jhep.2009.03.023
Murphy, 2009, Lipid droplet-organelle interactions; sharing the fats, Biochim. Biophys. Acta, 1791, 441, 10.1016/j.bbalip.2008.07.004
Musso, 2009, Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD), Prog. Lipid. Res., 48, 1, 10.1016/j.plipres.2008.08.001
Ong, 2011, Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning, Hepatology, 53, 116, 10.1002/hep.24006
Pfaffl, 2001, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res, 29, e45, 10.1093/nar/29.9.e45
Pol, 2014, Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites, J. Cell Biol., 204, 635, 10.1083/jcb.201311051
Pu, 2011, Interactomic study on interaction between lipid droplets and mitochondria, Protein Cell, 2, 487, 10.1007/s13238-011-1061-y
Reid, 2008, Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis, J. Biol. Chem., 283, 13087, 10.1074/jbc.M800533200
Silvestri, 2015, BN-PAGE-based approach to study thyroid hormones and mitochondrial function, Methods Mol. Biol., 1241, 111, 10.1007/978-1-4939-1875-1_10
Smirnova, 2006, ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells, EMBO Rep., 7, 106, 10.1038/sj.embor.7400559
Stenmark, 2009, Rab GTPases as coordinators of vesicle traffic, Nat. Rev. Mol. Cell Biol, 10, 513, 10.1038/nrm2728
Sztalryd, 2006, Functional compensation for adipose differentiation- related protein (ADFP) by Tip47 in an ADFP null embryonic cell line, J. Biol. Chem., 281, 34341, 10.1074/jbc.M602497200
Thiam, 2013, The biophysics and cell biology of lipid droplets, Nat. Rev. Mol. Cell Biol., 14, 775, 10.1038/nrm3699
Towbin, 1979, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications, Proc. Natl. Acad. Sci. U.S.A., 72, 4350, 10.1073/pnas.76.9.4350
Watt, 2008, Regulation and function of triacylglycerol lipases in cellular metabolism, Biochem. J., 414, 313, 10.1042/BJ20080305
Wiechelman, 1988, Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation, Anal. Biochem., 175, 231, 10.1016/0003-2697(88)90383-1
Yao, 2013, Microsome-associated lumenal lipid droplets in the regulation of lipoprotein secretion, Curr. Opin. Lipidol., 24, 160, 10.1097/MOL.0b013e32835aebe7
Yu, 2015, Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment, Biochim. Biophys. Acta, 1853, 918, 10.1016/j.bbamcr.2015.01.020