Tricking the devil with an engineered protein switch for ex vivo blood cell production
R. Windisch1, S. Soliman1, A. Hoffmann2,3, L. Chen-Wichmann1, C. Kellner1, E. Redondo-Monte4,5,6, L. Hartmann4,5,6, S. Schneider4,7,8, J. Bernhagen2, H. Klump9, A. Humpe1, P. Greif4,5,6, C. Wichmann1
1Department of Transfusion Medicine, Cell Therapeutics and Hemostaseology, University Hospital LMU Munich, Munich, Germany
2Department of Vascular Biology, Institute for Stroke and Dementia Research, LMU Munich, Munich, Germany
3Department of Anaesthesiology, University Hospital, LMU Munich, Munich, Germany
4Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
5German Cancer Consortium (DKTK), Munich, Germany
6German cancer Research Center (DKFZ), Heidelberg, Germany
7Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital LMU Munich, Munich, Germany
8Institute of Human Genetics, University Hospital, LMU Munich, Munich, Germany
9Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany