Treatment perspectives for medication-related osteonecrosis of the jaw (MRONJ)

American Association of Oral and Maxillofacial Surgeons, 2007, American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws, J Oral Maxillofac Surg, 65, 369, 10.1016/j.joms.2006.11.003

Agrillo, 2012, Bisphosphonate-related osteonecrosis of the jaw (BRONJ): 5 year experience in the treatment of 131 cases with ozone therapy, Eur Rev Med Pharmacol Sci, 16, 1741

Assaf, 2014, Intraoperative efficiency of fluorescence imaging by Visually Enhanced Lesion Scope (VELscope) in patients with bisphosphonate related osteonecrosis of the jaw (BRONJ), J Craniomaxillofac Surg, 42, e157, 10.1016/j.jcms.2013.07.014

Badros, 2008, Natural history of osteonecrosis of the jaw in patients with multiple myeloma, J Clin Oncol, 26, 5904, 10.1200/JCO.2008.16.9300

Bedogni, 2014, Staging of osteonecrosis of the jaw requires computed tomography for accurate definition of the extent of bony disease, Br J Oral Maxillofac Surg, 52, 603, 10.1016/j.bjoms.2014.04.009

Carlson, 2014, Management of antiresorptive osteonecrosis of the jaws with primary surgical resection, J Oral Maxillofac Surg, 72, 655, 10.1016/j.joms.2013.12.007

Carlson, 2009, The role of surgical resection in the management of bisphosphonate-related osteonecrosis of the jaws, J Oral Maxillofac Surg, 67, 85, 10.1016/j.joms.2009.01.006

Cella, 2011, Autologous bone marrow stem cell intralesional transplantation repairing bisphosphonate related osteonecrosis of the jaw, Head Face Med, 7, 16, 10.1186/1746-160X-7-16

Cheung, 2010, Teriparatide therapy for alendronate-associated osteonecrosis of the jaw, N Engl J Med, 363, 2473, 10.1056/NEJMc1002684

Curi, 2011, Bisphosphonate-related osteonecrosis of the jaws–an initial case series report of treatment combining partial bone resection and autologous platelet-rich plasma, J Oral Maxillofac Surg, 69, 2465, 10.1016/j.joms.2011.02.078

Dayisoylu, 2013, The effects of adjunctive parathyroid hormone injection on bisphosphonate-related osteonecrosis of the jaws: an animal study, Int J Oral Maxillofac Surg, 42, 1475, 10.1016/j.ijom.2013.05.001

Dayisoylu, 2014, Does an alkaline environment prevent the development of bisphosphonate-related osteonecrosis of the jaw? An experimental study in rats, Oral Surg Oral Med Oral Pathol Oral Radiol, 117, 329, 10.1016/j.oooo.2013.11.490

Dore, 2009, Bone scintigraphy and SPECT/CT of bisphosphonate-induced osteonecrosis of the jaw, J Nucl Med, 50, 30, 10.2967/jnumed.107.048785

Fabbricini, 2009, Bone scintigraphy and SPECT/CT in bisphosphonate-induced osteonecrosis of the jaw, J Nucl Med, 50, 1385, 10.2967/jnumed.109.064568

Fleisher, 2008, Tetracycline-guided debridement and cone beam computed tomography for the treatment of bisphosphonate-related osteonecrosis of the jaw: a technical note, J Oral Maxillofac Surg, 66, 2646, 10.1016/j.joms.2008.07.021

Graziani, 2012, Resective surgical approach shows a high performance in the management of advanced cases of bisphosphonate-related osteonecrosis of the jaws: a retrospective survey of 347 cases, J Oral Maxillofac Surg, 70, 2501, 10.1016/j.joms.2012.05.019

Groetz KA, Piesold J-U, Al-Nawas B (2012) Bisphosphonat-assoziierte Kiefernekrose (BP-ONJ) und andere Medikamenten-assoziierte Kiefernekrosen. In AWMF online (http://www.awmf.org).

Guggenberger, 2013, Bisphosphonate-induced osteonecrosis of the jaw: comparison of disease extent on contrast-enhanced MR imaging, [18F] fluoride PET/CT, and conebeam CT imaging, AJNR Am J Neuroradiol, 34, 1242, 10.3174/ajnr.A3355

Harris, 1960, A microscopic method of determining rates of bone growth, Nature, 188, 1038, 10.1038/1881038a0

Hoefert, 2011, Relevance of a prolonged preoperative antibiotic regime in the treatment of bisphosphonate-related osteonecrosis of the jaw, J Oral Maxillofac Surg, 69, 362, 10.1016/j.joms.2010.06.200

Hoff, 2008, Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates, J Bone Miner Res, 23, 826, 10.1359/jbmr.080205

Hutchinson, 2010, Radiographic findings in bisphosphonate-treated patients with stage 0 disease in the absence of bone exposure, J Oral Maxillofac Surg, 68, 2232, 10.1016/j.joms.2010.05.003

Jabbour, 2012, The outcomes of conservative and surgical treatment of stage 2 bisphosphonate-related osteonecrosis of the jaws: a case series, Int J Oral Maxillofac Surg, 41, 1404, 10.1016/j.ijom.2012.05.012

Khan, 2014, Diagnosis and management of osteonecrosis of the jaw: a Systematic Review and International Consensus, J Bone Miner Res

Khosla, 2007, Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research, J Bone Miner Res, 22, 1479, 10.1359/jbmr.0707onj

Kos, 2013, Pamidronate enhances bacterial adhesion to bone hydroxyapatite. Another puzzle in the pathology of bisphosphonate-related osteonecrosis of the jaw?, J Oral Maxillofac Surg, 71, 1010, 10.1016/j.joms.2012.12.005

Lemound, 2012, Bisphosphonate-associated osteonecrosis of the mandible: reliable soft tissue reconstruction using a local myofascial flap, Clin Oral Investig, 16, 1143, 10.1007/s00784-011-0596-x

Lerman, 2013, Conservative management of bisphosphonate-related osteonecrosis of the jaws: staging and treatment outcomes, Oral Oncol, 49, 977, 10.1016/j.oraloncology.2013.05.012

Lesclous, 2009, Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation?, Bone, 45, 843, 10.1016/j.bone.2009.07.011

Lorenzo, 2013, Histology of the oral mucosa in patients with BRONJ at III stage: a microscopic study proves the unsuitability of local mucosal flaps, J Clin Med Res, 5, 22

Marx, 2005, Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment, J Oral Maxillofac Surg, 63, 1567, 10.1016/j.joms.2005.07.010

Mast, 2012, Incidence of maxillary sinusitis and oro-antral fistulae in bisphosphonate-related osteonecrosis of the jaw, J Craniomaxillofac Surg, 40, 568, 10.1016/j.jcms.2011.10.012

Montebugnoli, 2007, Biphosphonate-associated osteonecrosis can be controlled by nonsurgical management, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 104, 473, 10.1016/j.tripleo.2007.01.008

Montefusco, 2008, Antibiotic prophylaxis before dental procedures may reduce the incidence of osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates, Leuk Lymphoma, 49, 2156, 10.1080/10428190802483778

Mücke, 2011, Outcome of treatment and parameters influencing recurrence in patients with bisphosphonate-related osteonecrosis of the jaws, J Cancer Res Clin Oncol, 137, 907, 10.1007/s00432-010-0953-1

O'Ryan, 2009, Intravenous bisphosphonate-related osteonecrosis of the jaw: bone scintigraphy as an early indicator, J Oral Maxillofac Surg, 67, 1363, 10.1016/j.joms.2009.03.005

Otto, 2009, The role of inferior alveolar nerve involvement in bisphosphonate-related osteonecrosis of the jaw, J Oral Maxillofac Surg, 67, 589, 10.1016/j.joms.2008.09.028

Otto, 2010, Bisphosphonate-related osteonecrosis of the jaw: is pH the missing part in the pathogenesis puzzle?, J Oral Maxillofac Surg, 68, 1158, 10.1016/j.joms.2009.07.079

Otto, 2012, Bisphosphonate-related osteonecrosis of the jaws – characteristics, risk factors, clinical features, localization and impact on oncological treatment, J Craniomaxillofac Surg, 40, 303, 10.1016/j.jcms.2011.05.003

Otto, 2010, Osteonecrosis or metastases of the jaw or both? Case report and review of the literature, J Oral Maxillofac Surg, 68, 1185, 10.1016/j.joms.2009.09.052

Pautke, 2010, Tetracycline bone fluorescence: a valuable marker for osteonecrosis characterization and therapy, J Oral Maxillofac Surg, 68, 125, 10.1016/j.joms.2009.05.442

Pautke, 2011, Fluorescence-guided bone resection in bisphosphonate-related osteonecrosis of the jaws: first clinical results of a prospective pilot study, J Oral Maxillofac Surg, 69, 84, 10.1016/j.joms.2010.07.014

Pautke, 2009, Fluorescence-guided bone resection in bisphosphonate-associated osteonecrosis of the jaws, J Oral Maxillofac Surg, 67, 471, 10.1016/j.joms.2008.09.037

Pautke, 2006, In vivo tetracycline labeling of bone: an intraoperative aid in the surgical therapy of osteoradionecrosis of the mandible, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 102, e10, 10.1016/j.tripleo.2006.05.007

Pautke, 2010, Characterization of eight different tetracyclines: advances in fluorescence bone labeling, J Anat, 217, 76

Rauch, 2007, Intracortical remodeling during human bone development–a histomorphometric study, Bone, 40, 274, 10.1016/j.bone.2006.09.012

Ristow, 2014, Auto-fluorescence of the bone and its use for delineation of bone necrosis, Int J Oral Maxillofac Surg, 43, 1391, 10.1016/j.ijom.2014.07.017

Ruggiero, 2009, American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws–2009 update, J Oral Maxillofac Surg, 67, 2

Ruggiero, 2014, Medication-related osteonecrosis of the jaw – 2014 update, American Association of Oral and Maxillofacial Surgeons – AAOMS

Ruggiero, 2004, Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases, J Oral Maxillofac Surg, 62, 527, 10.1016/j.joms.2004.02.004

Schipmann, 2013, Osteopathology associated with bone resorption inhibitors – which role does Actinomyces play? A presentation of 51 cases with systematic review of the literature, J Oral Pathol Med, 42, 587, 10.1111/jop.12038

Sedghizadeh, 2008, Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy, J Oral Maxillofac Surg, 66, 767, 10.1016/j.joms.2007.11.035

Stockmann, 2010, Osteotomy and primary wound closure in bisphosphonate-associated osteonecrosis of the jaw: a prospective clinical study with 12 months follow-up, Support Care Cancer, 18, 449, 10.1007/s00520-009-0688-1

Van den Wyngaert, 2009, Initial experience with conservative treatment in cancer patients with osteonecrosis of the jaw (ONJ) and predictors of outcome, Ann Oncol, 20, 331, 10.1093/annonc/mdn630

Vescovi, 2012, Early surgical laser-assisted management of bisphosphonate-related osteonecrosis of the jaws (BRONJ): a retrospective analysis of 101 treated sites with long-term follow-up, Photomed Laser Surg, 30, 5, 10.1089/pho.2010.2955

Voss, 2012, Surgical treatment of bisphosphonate-associated osteonecrosis of the jaw: technical report and follow up of 21 patients, J Craniomaxillofac Surg, 40, 719, 10.1016/j.jcms.2012.01.005

Watters, 2013, Intravenous bisphosphonate-related osteonecrosis of the jaw: long-term follow-up of 109 patients, Oral Surg Oral Med Oral Pathol Oral Radiol, 115, 192, 10.1016/j.oooo.2012.05.017