Treatment of Chronic Bone Infection

Gristina, 1985, Adherent bacterial colonization in the pathogenesis of osteomyelitis, Science, 228, 990, 10.1126/science.4001933 Gristina, 1985, Bacterial adherence to biomaterials and tissue. The significance of its role in clinical sepsis, J Bone Joint Surg Am, 67, 264, 10.2106/00004623-198567020-00014 Costerton, 2005, Biofilm theory can guide the treatment of device-related orthopaedic infections, Clin Orthop Relat Res, 437, 7, 10.1097/00003086-200508000-00003 Buchholz, 1970, Depot effects of various antibiotics mixed with Palacos resins, Chirurg, 41, 511 Klemm, 1979, Gentamicin-PMMA-beads in treating bone and soft tissue infections (author’s transl), Zentralbl Chir, 104, 934 Neut, 2001, Biomaterial-associated infection of gentamicin-loaded PMMA beads in orthopaedic revision surgery, J Antimicrob Chemother, 47, 885, 10.1093/jac/47.6.885 Nelson, 2014, Sonication of antibiotic spacers predicts failure during two-stage revision for prosthetic knee and hip infections, Clin Orthop Relat Res, 472, 2208, 10.1007/s11999-014-3571-4 Tunney, 1998, Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery, Antimicrob Agents Chemother, 42, 3002, 10.1128/AAC.42.11.3002 Chang, 1992, Microbial adherence on poly(methyl methacrylate) (PMMA) surfaces, J Biomed Mater Res, 26, 197, 10.1002/jbm.820260206 Saginur, 2006, Multiple combination bactericidal testing of staphylococcal biofilms from implant-associated infections, Antimicrob Agents Chemother, 50, 55, 10.1128/AAC.50.1.55-61.2006 van de Belt, 2001, Infection of orthopedic implants and the use of antibiotic-loaded bone cements. A review, Acta Orthop Scand, 72, 557, 10.1080/000164701317268978 Cierny, 2003, A clinical staging system for adult osteomyelitis, Clin Orthop Relat Res, 7, 10.1097/01.blo.0000088564.81746.62 El-Azizi, 2005, In vitro activity of vancomycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci, Ann Clin Microbiol Antimicrob, 4, 2, 10.1186/1476-0711-4-2 Fux, 2004, Detachment characteristics and oxacillin resistance of Staphyloccocus aureus biofilm emboli in an in vitro catheter infection model, J Bacteriol, 186, 4486, 10.1128/JB.186.14.4486-4491.2004 2012 Smith, 2005, Biofilms and antibiotic therapy: Is there a role for combating bacterial resistance by the use of novel drug delivery systems?, Adv Drug Deliv Rev, 57, 1539, 10.1016/j.addr.2005.04.007 Masquelet, 2000, Reconstruction of the long bones by the induced membrane and spongy autograft, Ann Chir Plast Esthet, 45, 346 Christou, 2014, The Masquelet technique for membrane induction and the healing of ovine critical sized segmental defects, PLoS One, 9, e114122, 10.1371/journal.pone.0114122 Karger, 2012, Treatment of post-traumatic bone defects by the induced membrane technique, Orthop Traumatol Surg Res, 98, 97, 10.1016/j.otsr.2011.11.001 Ilizarov, 1969, Replacement of defects of long tubular bones by means of one of their fragments, Vestn Khir Im I I Grek, 102, 77 Arora, 2012, Distraction osteogenesis using a monolateral external fixator for infected non-union of the femur with bone loss, J Orthop Surg, 20, 185, 10.1177/230949901202000210 Low, 1996, Infection of vascularized fibular grafts, Clin Orthop, 163, 10.1097/00003086-199602000-00022 Papakostidis, 2013, Distraction osteogenesis in the treatment of long bone defects of the lower limbs: Effectiveness, complications and clinical results; a systematic review and meta-analysis, Bone Joint J, 95-B, 1673, 10.1302/0301-620X.95B12.32385 Hazlett, 1954, The use of cancellous bone grafts in the treatment of subacute and chronic osteomyelitis, J Bone Joint Surg Br, 36-B, 584, 10.1302/0301-620X.36B4.584 Ammon, 2004, Allograft bone in two-stage revision of the hip for infection, J Bone Joint Surg Br, 86, 962, 10.1302/0301-620X.86B7.14292 Katz, 2009, Incorporation and immunogenicity of cleaned bovine bone in a sheep model, J Biomater Appl, 24, 159, 10.1177/0885328208095174 Friedlaender, 1991, Bone allografts: The biological consequences of immunological events, J Bone Joint Surg Am, 73, 1119, 10.2106/00004623-199173080-00001 Thoren, 1995, Increased bone ingrowth distance into lipid-extracted bank bone at 6 weeks. A titanium chamber study in allogeneic and syngeneic rats, Arch Orthop Trauma Surg, 114, 167, 10.1007/BF00443391 Greene, 1998, In vitro elution of tobramycin and vancomycin polymethylmethacrylate beads and spacers from Simplex and Palacos, Am J Orthop, 27, 201 Masri, 1998, Long-term elution of antibiotics from bone-cement: An in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system, J Arthroplasty, 13, 331, 10.1016/S0883-5403(98)90179-6 Bertazzoni Minelli, 2004, Release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty, J Antimicrob Chemother, 53, 329, 10.1093/jac/dkh032 Walenkamp, 2001, Gentamicin PMMA beads and other local antibiotic carriers in two-stage revision of total knee infection: A review, J Chemother, 13, 66, 10.1179/joc.2001.13.Supplement-2.66 Edin, 1996, Effect of cefazolin and vancomycin on osteoblasts in vitro, Clin Orthop Relat Res, 245 Buttaro, 2005, High active local levels of vancomycin without nephrotoxicity released from impacted bone allografts in 20 revision hip arthroplasties, Acta Orthop, 76, 336, 10.1080/00016470510030797 Witso, 2000, Cancellous bone as an antibiotic carrier, Acta Orthop Scand, 71, 80, 10.1080/00016470052943955 Witso, 1999, Adsorption and release of antibiotics from morselized cancellous bone. In vitro studies of 8 antibiotics, Acta Orthop Scand, 70, 298, 10.3109/17453679908997812 Buttaro, 2005, Vancomycin-supplemented impacted bone allografts in infected hip arthroplasty. Two-stage revision results, J Bone Joint Surg Br, 87, 314, 10.1302/0301-620X.87B3.14788 Winkler, 2000, In vitro release of vancomycin and tobramycin from impregnated human and bovine bone grafts, J Antimicrob Chemother, 46, 423, 10.1093/jac/46.3.423 Gorur, 2009, Biofilm removal with a dental water jet, Compend Contin Educ Dent, 30, 1 Fages, 1998, Viral inactivation of human bone tissue using supercritical fluid extraction, Asaio J, 44, 289, 10.1097/00002480-199807000-00009 Fages, 1994, Use of supercritical CO2 for bone delipidation, Biomaterials, 15, 650, 10.1016/0142-9612(94)90162-7 Frayssinet, 1998, Histological integration of allogeneic cancellous bone tissue treated by supercritical CO2 implanted in sheep bones, Biomaterials, 19, 2247, 10.1016/S0142-9612(98)00124-0 Watanakunakorn, 1982, Synergism between vancomycin and gentamicin or tobramycin for methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains, Antimicrob Agents Chemother, 22, 903, 10.1128/AAC.22.5.903 Gonzalez Della Valle, 2001, Effective bactericidal activity of tobramycin and vancomycin eluted from acrylic bone cement, Acta Orthop Scand, 72, 237, 10.1080/00016470152846547